Top Senior Machine Learning Jobs in Indianapolis, IN

Lead technical pre-sales for large Oil, Gas & Energy accounts, define and implement Databricks-based data and ML/AI strategies, build technical champions, mentor teammates, and drive enterprise adoption through technical leadership and value selling.

Lead design, execution, and interpretation of A/B tests and quasi-experiments; apply causal inference methods; partner with product, engineering, and marketing; mentor data scientists; build experimentation frameworks; extract and analyze data using SQL and Python; communicate results to stakeholders.

Design, productionize, and deploy machine learning forecasting models for ad inventory and campaign performance in low-latency, real-time advertising environments. Build scalable simulation, budgeting, and pacing systems; collaborate with cross-functional teams to deploy models at scale and optimize ad monetization.

Lead research and experimentation to measure ad campaign performance and effectiveness. Design evaluation frameworks, build measurement solutions, develop models for lift, conversion, and attribution, run experiments and analyses, partner with product/engineering/design/sales, present insights, mentor teammates, and foster technical community and culture.

Lead integration of GenAI into game engines and production pipelines. Prototype AI-native gameplay with designers, optimize inference latency and memory to preserve framerate, build automation tools for asset and design workflows, mentor engineers, and translate research and open-source models into production-ready systems aligned with player experience.

Build and operate scalable, highly available ML/LLM serving and compute infrastructure. Own long-term platform vision, deliver zero-to-one projects, partner cross-functionally, optimize performance and capacity, and support production ML models at scale.

Lead design and execution of scalable experimentation frameworks for Netflix Ads. Develop auction-based, biddable media models, solve cold-start measurement problems globally, apply causal inference and ML, partner with product and engineering, and translate analytic results into strategic recommendations to optimize marketplace dynamics and member experience.

Lead design of Netflix's ads consumer experiences, building GenAI-powered pipelines, prototyping AI-driven ad formats, ensuring privacy/regulatory compliance, collaborating with product, engineering, and data science to scale personalized advertising across surfaces.

Lead integration of state-of-the-art AI/ML into Netflixs content platform and publishing tools. Build roadmaps, incubate ML systems from idea to production, partner with researchers and engineers, automate promotional asset creation, optimize distribution and localization, and measure impact with data-driven evaluation.

Lead design, execution, and optimization of scaled lifecycle campaigns across email and in-product channels. Use marketing automation, behavioral data, and ML techniques to personalize journeys, drive activation, revenue, retention, and cross-sell. Analyze performance, generate insights, and collaborate with Growth, Product, Engineering, Data Science, Analytics, Sales, and Marketing stakeholders.

As a Staff Applied ML Scientist, you will develop and maintain fraud detection models, conduct research on fraud types, and collaborate across teams to drive product development and real-time decision-making.

As a Senior Applied ML Scientist, you'll develop fraud detection models, research new fraud types, and write production code while collaborating across teams to enhance SentiLink's identity verification solutions.

As a Principal Software Engineer, you'll architect and code backend services and ML models, integrate them with Salesforce, and mentor junior engineers.

Lead and build a team that drafts and submits state-specific rating rules, underwriting guidelines, and forms; manage filing execution via SERFF, handle objection responses, coordinate cross-functional stakeholders, establish operating rhythms, improve documentation and controls, and coach staff to scale filing expertise and regulatory execution.

Contribute to building and scaling ML development infrastructure for Copilot: design and optimize CI/CD for large-scale training, build developer tools, maintain multi-cloud infrastructure, and deploy/host models for inference and data generation while collaborating with cross-functional teams to improve reliability, performance, and model development workflows.

Lead and build Adelphi's end-to-end talent acquisition function, focusing initially on sourcing and closing Forward Deployed AI Engineers for defense and intelligence customers. Own full-cycle recruiting, structured scorecard-based interviewing, candidate experience, offer negotiation, recruiting infrastructure, and vendor/tool management while partnering with executive leadership.

Own strategy and execution to expand Pagaya's auto asset class: drive end-to-end enterprise sales to OEMs, banks, and dealers; close complex deals; build C-level relationships; coordinate across Risk, Tech, Product, Legal, and Data; monitor market trends; and evangelize Pagaya externally.

The Senior Product Manager will set product direction, own the development lifecycle, collaborate with teams, and ensure high-quality outputs. This role requires strong opinions on product quality and customer insights.

Lead the Decision Science function, designing ML models, overseeing experimentation frameworks, and ensuring model adoption across the company, driving operational and commercial improvements.

Lead Data Science initiatives, build AI/ML solutions, and mentor teams in a collaborative environment, driving innovation in a leading construction equipment venture.

Lead sales operations for seller acquisition at a marketplace: design pipeline and lead flows, remove onboarding friction, build SOT dashboards and forecasts, track listing health and KPIs, design incentive and quota programs, own CRM and sales enablement, and implement AI-driven automation and predictive analytics to scale seller and listing growth.

Lead and align ML, data, and engineering teams to define multi-year AI roadmaps, deliver production ML solutions, ensure robust data pipelines, set success metrics tied to business outcomes, and grow/mentor senior managers and engineers.

Own end-to-end modeling for vendor matching, order routing, and supply-chain optimization. Build predictive, causal, RL and OR solutions; design autonomous decision logic; quantify counterfactual impact; ship production models with data engineering; mentor senior data scientists; write technical design docs; partner on quarterly priorities and expand into revenue cycle and finance domains.

Lead and build a data science organization to create a prediction engine for vendor matching, order routing, and supply chain optimization. Anchor projects to P&L, design measurement and experiment frameworks, ship rapid wins, hire and coach data scientists, work hands-on in modeling and technical design, partner with product and engineering (Snowflake), and evolve systems toward agentic AI while reporting impact in dollar terms.

Build, ship, and own end-to-end ML models for vendor matching, order routing, and supply-chain optimization. Partner with data engineering to productionize models, quantify impact, document work, and implement decision logic components toward agentic AI in a fast-moving healthcare startup environment.