Top Senior Data Science Jobs in Indianapolis, IN

Lead evaluation and data strategy for advanced AI, vision, and perception systems. Define metrics, build evaluation frameworks, audit artifacts, prioritize fixes, and translate model behavior into product decisions and data-improvement loops to ensure production readiness and downstream usefulness.

Provide analytics and data-driven insights for CoverMyMeds clients, prioritize work that drives commercial outcomes, build relationships with account teams, apply statistical and predictive methods, monitor portfolio health, deliver client-facing visuals and recommendations, support complex requests and escalations, and inform strategic decisions across product, analytics, and operations.

The Principal Data Scientist will design, develop, and deploy machine learning models, innovating methodologies and collaborating across teams to enhance financial decision-making and risk management.

Develop and deploy production-grade machine learning and AI solutions for fleet analytics, logistics optimization, forecasting, anomaly detection, predictive maintenance, and operational decision-making. Build batch and real-time data pipelines, MLOps workflows, streaming analytics, LLM and RAG systems, analytical data models, and stakeholder dashboards using cloud platforms. Collaborate cross-functionally to translate business challenges into scalable data science solutions while supporting model governance, monitoring, experimentation, and documentation.

Own the analytical function for a business area such as growth, product, AI and automation, or strategic partnerships. Define business problems, metrics, reports, analyses, and experiments; generate actionable insights; communicate recommendations; and drive decisions and outcomes with cross-functional stakeholders. The role requires strong SQL or Python skills, independent data work, analytical problem-solving, and leadership-level influence.

Own end-to-end data science for a core business area such as growth, product, AI and automation, or strategic partnerships. Define business problems, metrics, reports, analyses, and experiments; surface insights; and drive recommendations and decisions with cross-functional stakeholders. The role requires independent data work, strong analytical thinking, clear communication, and ownership of ambiguous problems that deliver measurable business impact.

Leads technical support for VA healthcare AI citizen developers, developing and validating supervised, unsupervised, and reinforcement learning models. Builds synthetic healthcare data cohorts, designs secure cloud-based data science workflows, collaborates with federal stakeholders, interprets analytical results, mentors developers, and ensures model quality, documentation, privacy, governance, and regulatory compliance.

Lead end-to-end data science for a priority vertical (Insurance), building, validating, and deploying ML models that drive ROAS and lead quality. Partner with stakeholders and ML engineering to monitor live performance, iterate models, and identify new modeling opportunities to improve revenue and media efficiency.

Design, develop, and evaluate conversational AI agents and generative AI products. Collaborate with AI scientists, ML engineers, and Responsible AI/Model Validation teams to ensure state-of-the-art, ethical solutions and support deployment and integration of conversational systems.

The Lead Risk Analytics Data Scientist will develop risk pricing, design data models, automate workflows, and communicate insights to leadership. Responsibilities include owning the risk narrative, building analytics foundations, and utilizing AI to enhance efficiency.

Oversee development, validation, monitoring, and governance of consumer credit risk models used for loss forecasting, credit decisioning, regulatory reporting, and risk management. Apply statistical, econometric, and machine learning methods to PD, LGD, and EAD models; support CECL, stress testing, and macroeconomic scenario analysis. Assess model performance, data quality, and compliance while communicating findings to senior leaders, auditors, regulators, and other stakeholders.

Lead development and deployment of large-scale LLM and GenAI solutions for cybersecurity. Drive research strategy, model training, evaluation, safety/red-teaming, and cross-functional productization. Mentor data scientists, set technical standards, and represent the team through publications and thought leadership.

Develop and refine predictive models, perform exploratory data analysis, and generate AI-driven insights for DoD missions. Integrate multi-source data, apply geospatial analytics, iterate models via Agile sprints, produce performance and cost reports, and optimize analytic workflows for operational deployment.

Designs AI risk stratification and evaluation methodologies for Veterans Health Administration systems, assessing performance, fairness, value, and post-deployment monitoring. Provides technical guidance on machine learning, healthcare data models, cohorts, synthetic data, and pilot evaluations. Develops risk management materials and supports governance decisions through quantitative analysis. Requires extensive applied data science experience, advanced education, and expertise in healthcare-focused machine learning.

Lead statistical modeling, AI/ML evaluation, data governance, data quality assurance, and executive analytics for VA EHR modernization. Build reproducible R-based analytics, reporting pipelines, dashboards, and governed data products using R, SQL, Python, Git, and cloud platforms. Evaluate model reliability, bias, drift, and operational value; integrate complex healthcare data; define metrics and validation rules; and advise stakeholders on auditable analytical practices.

Develop and deploy AI, machine learning, statistical, and adaptive process-control models for bioprocess optimization. Analyze sensor, batch, and experimental data; improve fermentation and downstream processing productivity, yield, cost, and scalability. Collaborate with engineers and scientists to integrate data science solutions into manufacturing and R&D operations, enhance data pipelines and modeling frameworks, and communicate findings to technical and non-technical stakeholders.

Lead research and experimentation to measure ad campaign performance and effectiveness. Design evaluation frameworks, build measurement solutions, develop models for lift, conversion, and attribution, run experiments and analyses, partner with product/engineering/design/sales, present insights, mentor teammates, and foster technical community and culture.

Lead design, execution, and interpretation of A/B tests and quasi-experiments; apply causal inference methods; partner with product, engineering, and marketing; mentor data scientists; build experimentation frameworks; extract and analyze data using SQL and Python; communicate results to stakeholders.

Leads enterprise manufacturing AI, machine learning, and Industry 4.0 initiatives across multiple plants. Develops and deploys solutions for predictive maintenance, process and quality optimization, energy efficiency, throughput, and OEE improvement. Establishes scalable data and AI platforms, governance, and MLOps standards while integrating industrial data sources. Leads and mentors data science teams, prioritizes projects, allocates resources, partners with cross-functional manufacturing stakeholders, and presents strategic recommendations and business cases to executives.

Senior Data Scientist partnering with Product, Engineering, and Design teams to analyze user behavior, product performance, and marketplace dynamics. Responsibilities include developing metrics and reporting frameworks, designing experiments, diagnosing business trends, analyzing marketplace behavior, and aligning stakeholders on analytical priorities. The role uses SQL and Python alongside BigQuery, dbt Cloud, Airflow, Tableau, and Statsig, with a focus on product analytics, experimentation, and data-informed decision-making.

Develop and deploy statistical and machine learning models supporting credit risk, fraud, collections, and marketing. Responsibilities include data exploration, model design, testing, production monitoring, performance analysis, governance, and stakeholder communication. The role partners with Legal and Compliance, translates business questions into analytical solutions, researches new methods, and provides data-driven recommendations to leadership.

Design and deploy predictive forecasting and analytics to support Revenue operations. Build models for forecasting, churn, expansion, and pipeline analytics; create scalable dashboards; partner with Revenue Operations, Finance, and Data Engineering to improve data quality, KPI governance, and executive reporting to drive data-driven decisions and AI readiness.

Own end-to-end modeling for vendor matching, order routing, and supply-chain optimization. Build predictive, causal, RL and OR solutions; design autonomous decision logic; quantify counterfactual impact; ship production models with data engineering; mentor senior data scientists; write technical design docs; partner on quarterly priorities and expand into revenue cycle and finance domains.

Senior individual contributor who drives product analytics, experimentation, and applied modeling. Owns growth and performance analyses, designs experiments with robust statistical evaluation, builds repeatable reporting, and partners with Product, Engineering, Operations, Clinical, and Finance to translate data into actionable product and operational decisions.

Build and scale production-ready generative AI applications: design multi-agent workflows, implement advanced RAG with vector DBs, integrate/swap LLMs, fine-tune models, and deploy scalable FastAPI/Docker services with monitoring and optimization for latency, cost, and reliability.