Top Senior Data Science Jobs in Indianapolis, IN

6 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Software
The Senior Data Scientist will design ML-based entity resolution systems, build and refine NLP and ML models, and translate model results into business impact while supporting data strategy and improving data pipelines.
Top Skills: AWSAzureElasticsearchGCPLucenePythonPyTorchScikit-LearnSnowflakeSQLTensorFlowXgboost
Reposted 6 Days AgoSaved
Remote
Indianapolis, IN
142K-196K Annually
Senior level
142K-196K Annually
Senior level
Healthtech
Design and implement AI agents for autonomous goal management, evaluating alignment with human intent and integrating safety mechanisms while leading AI/ML system development.
Top Skills: AutogenJaxLangchainLanggraphPythonPyTorchSQL
Reposted 6 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Consumer Web
Seeking a Senior Data Scientist to analyze user behavior, collaborate with teams, develop metrics, and drive analytical priorities in a two-sided marketplace.
Top Skills: AirflowDbt CloudGitGoogle BigqueryPythonSQLStatsigTableau
Reposted 7 Days AgoSaved
Remote
Indianapolis, IN
160K-200K Annually
Senior level
160K-200K Annually
Senior level
AdTech • Fintech • Marketing Tech
The Senior Data Scientist will develop machine learning models, conduct A/B tests, and work with behavioral data to enhance customer engagement and partner ROI.
Top Skills: AirflowAWSDbtGCPPythonPyTorchSparkSQLXgboost
Reposted 8 Days AgoSaved
In-Office or Remote
Indianapolis, IN
Senior level
Senior level
Gaming • Web3
As a Senior Data Scientist, you will own data, collaborate with engineers and stakeholders, and build tools for analytics and dashboards to inform business decisions.
Top Skills: AirflowEmrImply DruidKafkaPythonRScalaSQLTrino
Reposted 8 Days AgoSaved
Remote
Indianapolis, IN
183K-224K Annually
Senior level
183K-224K Annually
Senior level
Fintech
As a Principal Data Scientist, you'll design and deploy cutting-edge machine learning models to drive financial success for customers and guide technical teams.
Top Skills: AirflowKubernetesMachine LearningMlflowNumpyPandasScikit-LearnSpark
Reposted 8 Days AgoSaved
Remote
Indianapolis, IN
183K-224K Annually
Senior level
183K-224K Annually
Senior level
Fintech
The Principal Data Scientist will design, develop, and deploy machine learning models, innovating methodologies and collaborating across teams to enhance financial decision-making and risk management.
Top Skills: AirflowBentomlChalkDvcKubernetesMachine LearningMlflowNumpyPandasPydata StackScikit-LearnSpark
Reposted 9 Days AgoSaved
Remote
Indianapolis, IN
140K-165K Annually
Senior level
140K-165K Annually
Senior level
Fintech • Payments
The Sr. Data Scientist will optimize risk solutions using machine learning and statistical methods, develop models, mentor juniors, and collaborate with stakeholders on credit risk management.
Top Skills: Aws SagemakerLightgbmPandasPythonRScikit-LearnSQL
Reposted 10 Days AgoSaved
Remote
Indianapolis, IN
180K-230K Annually
Senior level
180K-230K Annually
Senior level
Information Technology
As a Senior Data Scientist, you'll develop fraud detection models, perform detailed analyses, and work closely with teams to drive product innovation and business outcomes.
Top Skills: Aws Ec2Aws RdsAws RedshiftAws S3PostgresPython 3
11 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Healthtech • Professional Services • Biotech • Pharmaceutical
The Senior Data Scientist will manage data collection, design study protocols, train juniors, lead report development, and support innovative analytics tools.
Top Skills: Data AnalysisMachine LearningProject Management FrameworksStatistical Analysis
11 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Healthtech • Professional Services • Biotech • Pharmaceutical
The Senior Data Scientist oversees data collection and preparation, designs study protocols, leads report development, trains junior employees, and manages project workstreams while collaborating with team members to optimize business performance.
Top Skills: Data ManagementProject Management FrameworksQuantitative Analysis
11 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Big Data • Marketing Tech • Analytics
As a Data Engineering Analyst Lead/Scientist, you will engineer consumer attributes, apply statistical techniques, build visualizations, and collaborate across teams to maximize impact in financial services.
Top Skills: AWSPythonSQLTableau
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11 Days AgoSaved
Remote
Indianapolis, IN
106K-168K Annually
Senior level
106K-168K Annually
Senior level
Other • Social Impact
The Senior Data Scientist will integrate data from various sources, analyze web performance, and provide insights for strategic decision-making. Responsibilities include developing automated systems for content coverage, tracking metrics, and designing experiments to assess new initiatives' impact.
Top Skills: AhrefsBigQueryDruidHiveJupyterMatomoPrestoPythonQuartoSemrushSparkSQLSuperset
Reposted 11 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Artificial Intelligence • Big Data • Information Technology
Design, build, and deploy end-to-end production ML systems for audience targeting, lookalike generation, and propensity scoring. Own ML lifecycle from experimentation to production monitoring, leverage distributed/cloud platforms, implement vector similarity and embedding systems, engineer scalable features, and collaborate with engineering and product teams to ensure model quality and operational reliability.
Top Skills: Aws S3Ci/CdDatabricksFaissGitPythonSnowflakeSparkSQL
Reposted 11 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Security
The Geospatial Scientist leads data management initiatives, oversees data governance, and ensures quality and compliance of geospatial data for DHS.
Top Skills: Arcgis EnterpriseEsri Geoportal ServerGeoplatform.GovGis Systems
Reposted 11 Days AgoSaved
Remote
Indianapolis, IN
95K-159K Annually
Senior level
95K-159K Annually
Senior level
Retail • Sports
Lead the design and implementation of AI-driven search algorithms and models. Collaborate with teams to optimize search performance and personalize user experiences. Mentor junior staff and stay updated on latest AI advancements.
Top Skills: Azure DevopsElasticJIRAKafkaLangchainOpenaiPythonPyTorchSolrSparkTensorFlow
Reposted 11 Days AgoSaved
Remote
Indianapolis, IN
150K-170K Annually
Senior level
150K-170K Annually
Senior level
Biotech
Lead development and operationalization of LLM, agentic, and image AI solutions for diagnostics. Build multimodal datasets, implement RAG and agent workflows, apply ML and statistical methods (DoE, Bayesian optimization, causal/survival/longitudinal), analyze RWE/RWD, and integrate insights across clinical, regulatory, and product teams to drive diagnostic and business impact.
Top Skills: Agentic AiAzureBayesian OptimizationCausal InferenceClaimsConfluenceDatabricksDesign Of ExperimentsDevice Telemetry/LogsImage AiLlmsLongitudinal MethodsModern Ml FrameworksPythonRRegistries)Retrieval-Augmented Generation (Rag)Rwe/Rwd (EhrSharepointSnowflakeSurvival AnalysisVector Databases
Reposted 11 Days AgoSaved
Remote
Indianapolis, IN
150K-170K Annually
Senior level
150K-170K Annually
Senior level
Healthtech • Other • Software • Biotech
Lead development and operationalization of LLMs, agentic and image AI solutions; build multimodal datasets; develop production-grade models, RAG pipelines and agent workflows; run RWE analytics and Bayesian optimization for assay/R&D acceleration; deploy solutions on Azure/Snowflake/Databricks and integrate insights into clinical, regulatory, and product programs.
Top Skills: Agent WorkflowsAgentic AiAzureBayesian OptimizationCausal MethodsConfluenceDatabricksDesign Of Experiments (Doe)Image AiLlmsLongitudinal MethodsModern Ml FrameworksPythonRRagSharepointSnowflakeSurvival AnalysisVector Databases
Reposted 11 Days AgoSaved
Remote
Indianapolis, IN
150K-170K Annually
Senior level
150K-170K Annually
Senior level
Healthtech
Lead development and operationalization of LLM, agentic, and image AI solutions for diagnostics. Build multimodal datasets, develop production-grade models and RAG/agent pipelines, perform RWE analytics, and integrate insights across clinical, regulatory, R&D, and product teams to drive diagnostic performance and patient impact.
Top Skills: Agentic AiAzureAzure OpenaiClaudeCodexConfluenceDatabricksDelta LakeHugging FaceImage AiLlamaLlmsMistralMlflowPythonRRagSharepointSnowflakeVector DatabasesVs Code
Reposted 12 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Big Data • Analytics • Business Intelligence • Big Data Analytics
The Senior Data Scientist will analyze manufacturing data to improve quality and optimize processes through advanced analytics, with a focus on driving cost and waste reduction.
Top Skills: AIData ScienceMachine Learning
Reposted 12 Days AgoSaved
Remote
Indianapolis, IN
215K-260K Annually
Senior level
215K-260K Annually
Senior level
Security • Software
Lead Data Scientist responsible for creating ML-driven risk assessments and AI workflows within a SaaS security platform, ensuring effective decision-making and system reliability.
Top Skills: AIMachine LearningStatistical Modeling
13 Days AgoSaved
Remote
Indianapolis, IN
165K-185K Annually
Senior level
165K-185K Annually
Senior level
Cloud • Marketing Tech • Sales • Software
As a Senior GTM Data Scientist, you will develop predictive models, analyze experiments, and provide actionable insights to GTM teams.
Top Skills: AirflowDatabricksDbtNumpyPandasPythonRScikit-LearnSnowflakeSQL
Reposted 23 Days AgoSaved
In-Office or Remote
Indianapolis, IN
Senior level
Senior level
Consulting
Lead data science efforts to define metrics, build models of user and business behavior, design and analyze A/B tests, develop LLM-driven applications, maintain analytics and a data lakehouse, create dashboards, and partner cross-functionally to deliver actionable insights that drive product and business decisions.
Top Skills: Ai AgentsAmazon BedrockAnthropic ApiAWSAzureAzure Ai FoundryClaude CodeCsvCursorData LakehouseJIRAJSONLlmsN8NOpenai ApiOpenai CodexParquetPower BIPythonRagSnowflakeSQLXlsx
Reposted 14 Days AgoSaved
Remote
Indianapolis, IN
185K-225K Annually
Senior level
185K-225K Annually
Senior level
Software • Cryptocurrency
As a Data Scientist, you'll empower the company with data insights, develop metrics and experiments, and collaborate with various teams to drive product decisions.
Top Skills: PythonRSQL
Reposted 14 Days AgoSaved
Remote or Hybrid
Indianapolis, IN
180K-225K Annually
Senior level
180K-225K Annually
Senior level
Edtech • Fintech • Financial Services
The Lead Data Scientist will build pricing systems, lead experiments, mentor teammates, and influence strategy across various departments based on data-driven insights.
Top Skills: AirflowAWSDbtLookerPythonRSQL
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