Top Massachusetts Machine Learning Startups (100)

At Kensho, we leverage S&P Global’s world class data to research, develop and implement leading AI and machine learning capabilities that drive fact-based, objective decision making. Data is at the heart of Kensho, and it’s our technology. We build and deploy solutions that make that data accessible, insightful, relevant and transformative.

mabl is empowering software testers who are aiming to keep pace with today’s dev culture of high-paced software delivery. Making it easy for testers to create and run automated UI tests at scale, mabl buys back hours of time every week and finally brings functional UI testing to the modern era.

Gradient AI is revolutionizing Group Health and P&C insurance with AI-powered solutions that help insurers predict risk more accurately, improve profitability, and automate underwriting and claims. Our SaaS platform taps into one of the industry’s largest data lakes—tens of millions of policies and claims—to deliver deep, actionable insights. Trusted by leading carriers, MGAs, TPAs, and self-insured employers, Gradient AI has...

MORSE is a specially selected team of scientists, engineers, and software developers who use asymmetric and unconventional approaches to deploy practical solutions that solve difficult multi-disciplinary problems faced by the US National Security Ecosystem.

ASI is a dual-use software company that deploys predictive AI to the world's most complex operating environments. Backed by leading investors–including Andreessen Horowitz, Renegade Partners, and Spark Capital–we actively manage over 40% of all US air traffic across both public and private sector air operations. Partnering with major airlines like United and Alaska, we optimize thousands of flights daily, delivering...

Atomscale is building the future of atomic-scale engineering, applying AI to enable new material innovations.

Eight Sleep is building a predictive health platform powered by sleep, now used by 200k+ members nightly across 30+ countries. Our products combine hardware, software, AI, and biometric sensing to turn the bed into an always-on system that can measure physiology, regulate temperature in real time, and adapt throughout the night to improve sleep, recovery, and long-term health. The impact is...

Charles River Analytics conducts leading-edge AI, robotics, and human-machine interface R&D and leverages that R&D to create custom solutions. We bring foundational research to life, creating human-centered intelligent systems at the edge of what’s possible, through deep partnerships with our customers. We hire and nurture smart people so they can solve hard problems at the intersection of human and machine intelligence....

Matterworks is developing advanced AI-powered software and proprietary chemistry reagents to enable real-time, quantitative metabolomics to accelerate the research, development, and manufacturing of biologic therapeutics. Metabolomics measures all the small molecules a cell needs to function. In spite of its far-reaching potential impact across life science disciplines, adoption of metabolomics remains limited and lags behind other ‘omic techniques due to a...

Aquant's Service Intelligence platform gives field service teams the AI-powered tools they need to accurately troubleshoot business challenges as well as problems out in the field. Using a combination of Service Language Processing and Machine Learning, service leaders obtain actionable insights into the state of their organization, enabling them to make data-driven decisions. It also equips technicians with the knowledge...

Each year, billions are spent on pesticides and fertilizers, yet most never reach the crops - resulting in costly waste and significant environmental harm. We’re changing that. By using machine learning, computer vision, and fluid dynamics, AgZen optimizes chemical application in real time, reducing input use, minimizing pollution, and protecting both yields and ecosystems. Founded out of MIT and backed by...

Mobi’s Collaborative AI platform transforms how companies do business by enhancing their employee’s capabilities and enriching their customer’s experiences. Mobi’s technology builds on seven decades of research and advances in computing power to improve productivity, efficiency, and decision-making at scale. Companies work with us to use their data intelligently and AI thoughtfully, to make their digital offerings more human, and...

Manifold is an AI platform purpose-built for the life sciences industry, addressing a critical challenge: despite major advances in biology, data generation, and AI, progress in drug development has slowed due to fragmented data, brittle infrastructure, and workflows not designed for secure collaboration or AI-driven analysis. The Problem We Solve: Life sciences is a $2 trillion industry where productivity directly impacts patient...

Chloris Geospatial uses industry-leading technology to measure the amount of carbon stored in terrestrial ecosystems. Our state-of-the-art machine learning algorithms fuse data from multiple Earth observation satellites to provide high-quality above-ground biomass stock and change and forest cover/change data. Chloris supports companies and governments with monitoring data and insights into carbon and forest dynamics, for trustworthy investments in nature-based solutions. From...

Lightmatter is a startup photonics company that has pioneered a new paradigm in processor chip architecture that uses photons instead of electrons. Now the leader in the photonic AI compute “space race,” this new class of high performance semiconductors is the foundation of Lightmatter’s mission to enable the growth of computing, reduce harmful emissions associated with this growth, and democratize...

Lendbuzz is an AI-based auto finance platform that helps consumers with thin or no credit history obtain financing when purchasing a car. Powered by machine learning and proprietary algorithms, Lendbuzz can assess the creditworthiness of consumers with limited credit history—a group underserved by traditional banks. Through their auto dealership partners, Lendbuzz offers consumers attractive financing solutions while opening up opportunities...

Upgraid combines a vast array of data in our AI platform to understand the physical condition of any building. What equipment is in the building, how old is it, and when will it need to be replaced? What energy is being consumed? What is the condition of the roof, insulation, and windows? We put this information in the hands of...

Asimov builds tools to program living cells. By integrating mammalian synthetic biology, computer-aided design, and machine learning, our multi-disciplinary team is advancing the design and manufacture of biologics and gene therapies.

Monalee is a climate tech company that is accelerating the adoption of home solar, storage, and EV charging. Powered by advanced machine learning and by removing salespeople and system designers from the process, Monalee makes it possible for homeowners across the nation to go solar at half the price compared to traditional solar companies in their area. Founded in June 2022...

TruVideo is the leader in communication technology for the transportation industry, providing innovative, AI-powered video and messaging solutions that build trust and improve customer experiences. Today, thousands of dealerships and service centers use TruVideo and our technology powers the tools and solutions of the largest DMS companies in the world.