Top Massachusetts Machine Learning Startups (99)

At Kensho, we leverage S&P Global’s world class data to research, develop and implement leading AI and machine learning capabilities that drive fact-based, objective decision making. Data is at the heart of Kensho, and it’s our technology. We build and deploy solutions that make that data accessible, insightful, relevant and transformative.

MORSE is a specially selected team of scientists, engineers, and software developers who use asymmetric and unconventional approaches to deploy practical solutions that solve difficult multi-disciplinary problems faced by the US National Security Ecosystem.

ASI is a dual-use software company that deploys predictive AI to the world's most complex operating environments. Backed by leading investors–including Andreessen Horowitz, Renegade Partners, and Spark Capital–we actively manage over 40% of all US air traffic across both public and private sector air operations. Partnering with major airlines like United and Alaska, we optimize thousands of flights daily, delivering...

mabl is empowering software testers who are aiming to keep pace with today’s dev culture of high-paced software delivery. Making it easy for testers to create and run automated UI tests at scale, mabl buys back hours of time every week and finally brings functional UI testing to the modern era.

Gradient AI is revolutionizing Group Health and P&C insurance with AI-powered solutions that help insurers predict risk more accurately, improve profitability, and automate underwriting and claims. Our SaaS platform taps into one of the industry’s largest data lakes—tens of millions of policies and claims—to deliver deep, actionable insights. Trusted by leading carriers, MGAs, TPAs, and self-insured employers, Gradient AI has...

Rhino Federated Computing solves one of the biggest challenges in AI: seamlessly connecting siloed data through federated computing. The Rhino Federated Computing Platform (Rhino FCP) serves as the ‘data collaboration tech stack’, extending from providing computing resources to data preparation & discoverability, to model development & monitoring — all in a secure, privacy-preserving environment. To do this, Rhino FCP offers...

Lightmatter is a startup photonics company that has pioneered a new paradigm in processor chip architecture that uses photons instead of electrons. Now the leader in the photonic AI compute “space race,” this new class of high performance semiconductors is the foundation of Lightmatter’s mission to enable the growth of computing, reduce harmful emissions associated with this growth, and democratize...

Chloris Geospatial uses industry-leading technology to measure the amount of carbon stored in terrestrial ecosystems. Our state-of-the-art machine learning algorithms fuse data from multiple Earth observation satellites to provide high-quality above-ground biomass stock and change and forest cover/change data. Chloris supports companies and governments with monitoring data and insights into carbon and forest dynamics, for trustworthy investments in nature-based solutions. From...

Atomscale is building the future of atomic-scale engineering, applying AI to enable new material innovations.

At Activ Surgical, our mission is for every surgical imaging system to deliver intelligent information that reduces surgical complication rates, ushering in a new standard of patient care and safety. Having completed the world’s first autonomous robotic surgery of soft tissue in 2018, the company is focused on enhanced, real-time visualization capabilities for surgeons that combine advanced augmented reality (AR),...

Manifold is an AI platform purpose-built for the life sciences industry, addressing a critical challenge: despite major advances in biology, data generation, and AI, progress in drug development has slowed due to fragmented data, brittle infrastructure, and workflows not designed for secure collaboration or AI-driven analysis. The Problem We Solve: Life sciences is a $2 trillion industry where productivity directly impacts patient...

FundGuard is the new era investment accounting utility that is transforming legacy investment operations with our AI-powered, cloud native and multi-asset class SaaS platform for asset managers, asset owners, custodian banks and fund administrators. Led by an experienced team of technology innovators and industry experts, our mission is to help investors around the world to accumulate and grow their assets safely...

Each year, billions are spent on pesticides and fertilizers, yet most never reach the crops - resulting in costly waste and significant environmental harm. We’re changing that. By using machine learning, computer vision, and fluid dynamics, AgZen optimizes chemical application in real time, reducing input use, minimizing pollution, and protecting both yields and ecosystems. Founded out of MIT and backed by...

Lendbuzz is an AI-based auto finance platform that helps consumers with thin or no credit history obtain financing when purchasing a car. Powered by machine learning and proprietary algorithms, Lendbuzz can assess the creditworthiness of consumers with limited credit history—a group underserved by traditional banks. Through their auto dealership partners, Lendbuzz offers consumers attractive financing solutions while opening up opportunities...

Aquant's Service Intelligence platform gives field service teams the AI-powered tools they need to accurately troubleshoot business challenges as well as problems out in the field. Using a combination of Service Language Processing and Machine Learning, service leaders obtain actionable insights into the state of their organization, enabling them to make data-driven decisions. It also equips technicians with the knowledge...

Upgraid combines a vast array of data in our AI platform to understand the physical condition of any building. What equipment is in the building, how old is it, and when will it need to be replaced? What energy is being consumed? What is the condition of the roof, insulation, and windows? We put this information in the hands of...

Asimov builds tools to program living cells. By integrating mammalian synthetic biology, computer-aided design, and machine learning, our multi-disciplinary team is advancing the design and manufacture of biologics and gene therapies.

Modulate designs and builds prosocial voice intelligence, empowering platforms to transform voice interactions into safe, trustworthy experiences. Our flagship product, ToxMod, is a proactive voice moderation system that goes beyond keyword scanning. Utilizing layered machine learning models—designed to detect emotional tone, speech patterns, conversational context, and intent—ToxMod identifies toxic behaviors as they occur. This nuanced approach allows moderators and trust-and-safety teams...

Mobi’s Collaborative AI platform transforms how companies do business by enhancing their employee’s capabilities and enriching their customer’s experiences. Mobi’s technology builds on seven decades of research and advances in computing power to improve productivity, efficiency, and decision-making at scale. Companies work with us to use their data intelligently and AI thoughtfully, to make their digital offerings more human, and...

Matterworks is developing advanced AI-powered software and proprietary chemistry reagents to enable real-time, quantitative metabolomics to accelerate the research, development, and manufacturing of biologic therapeutics. Metabolomics measures all the small molecules a cell needs to function. In spite of its far-reaching potential impact across life science disciplines, adoption of metabolomics remains limited and lags behind other ‘omic techniques due to a...