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Top Massachusetts Biotech Startups (225)

Click Therapeutics
Healthtech • Biotech • App development
We deliver safe and effective digital treatments to patients in need.

Click Therapeutics, Inc., develops, validates, and commercializes software as prescription medical treatments for people with unmet medical needs. As a leading innovator of Digital Therapeutics™, Click delivers accessible, clinically proven, FDA-regulated prescription treatments to the smartphone in your hand. Click’s treatments are defined by a commitment to applying technical and scientific rigor and patient-centric design to the development process. This...

Click Therapeutics
Matterworks
Big Data • Machine Learning • Software • Analytics • Biotech
Somerville, Massachusetts, USA
25 Employees
15 Benefits Hiring Now
AI-Powered Tools to Engineer Biology

Matterworks is developing advanced AI-powered software and proprietary chemistry reagents to enable real-time, quantitative metabolomics to accelerate the research, development, and manufacturing of biologic therapeutics. Metabolomics measures all the small molecules a cell needs to function. In spite of its far-reaching potential impact across life science disciplines, adoption of metabolomics remains limited and lags behind other ‘omic techniques due to a...

Matterworks
Seaport Therapeutics
Boston, Massachusetts, USA
2 Employees
Hiring Now

Seaport Therapeutics is a clinical-stage biopharmaceutical company advancing the development of novel neuropsychiatric medicines in areas of high unmet patient needs. We have a proven strategy of advancing clinically validated mechanisms previously held back by limitations we overcome with our proprietary Glyph technology platform. All the therapeutic candidates in our pipeline of first and best-in-class medicines are based on the...

Seaport Therapeutics
Nanopath
Biotech
Cambridge, Massachusetts, USA
26 Employees
Hiring Now

Nanopath is a molecular diagnostics company disrupting traditional testing methodologies. We aim to improve the health of women by providing granular and clinically actionable information within a single office visit.

Nanopath
Atavistik Bio
Cambridge, Massachusetts, USA
28 Employees
Hiring Now

Atavistik Bio is a new, privately-held biopharmaceutical company focused on the discovery and development of novel therapies for metabolic diseases and cancer. Our high-throughput platform for the unbiased identification of metabolite-protein interactions will enable the discovery of first-in-class drugs inspired and empowered by nature’s own mechanisms of allosteric control. Our unique approach marries this validated platform with structure-aided drug design...

Atavistik Bio
Sail Biomedicines
Artificial Intelligence • Healthtech • Biotech
Somerville, Massachusetts, USA
122 Employees
Hiring Now

We work at the frontier of programmable medicines. We power our bioplatform and product candidates by harnessing evolution and AI. We operate with purpose and urgency on behalf of people everywhere. We aim to generate life-changing impact for the world

Sail Biomedicines
Praxis Precision Medicines, Inc.
Healthtech • Biotech
Boston, Massachusetts, USA
160 Employees
Hiring Now
The era of genetic neuroscience has arrived

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. Praxis is applying insights into the genetic mutations that drive excitation-inhibition imbalance in diseases to select biological targets for rare and more prevalent neurological disorders. We share a common vision of reshaping the human condition into...

Praxis Precision Medicines, Inc.
Remix Therapeutics
Cambridge, Massachusetts, USA
62 Employees
Hiring Now

Remix Therapeutics is a biotechnology company developing novel small molecule therapies designed to reprogram RNA processing and treat disease in entirely new ways.

Remix Therapeutics
Landmark Bio
Biotech
Watertown, Massachusetts, USA
81 Employees
42 Benefits Hiring Now
Landmark helps fast-track discovery research and bring life-changing therapies to more patients.

Landmark Bio is a collective endeavor launched by leaders from academia, the life sciences industry, and world-renowned research hospitals to accelerate development and industrialization of next-generation genomic medicine. Inspired by recent advancements in cell and gene therapy, Landmark Bio was established to remove barriers in drug development, create accessible capability, expertise, and solutions, and offer a collaboration platform to advance manufacturing...

Landmark Bio
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Synterex
Biotech
Dedham, Massachusetts, USA
32 Employees
Hiring Now

Synterex is a woman-owned, disability-owned business that provides clinical solutions, including publishing, clinical science, project management, medical and regulatory writing services, and IT collaboration services, from process development and optimization to document production. Our staffers are seasoned and dedicated, with extensive experience doing the work hands-on as well as building and leading teams. We are committed to applying our years of...

Synterex
ZAGENO Inc.
Biotech
Cambridge, Massachusetts, USA
147 Employees
Hiring Now

ZAGENO is on a mission to accelerate scientific innovation by streamlining biotech purchasing processes with its award-winning, first-of-its-kind e-commerce platform. With over 25 million product SKUs available from more than 5,000 unique product brands, ZAGENO makes online shopping for any research material convenient, efficient and reliable. The ZAGENO experience includes its Scientific Score, a best-in-class product rating system that offers...

ZAGENO Inc.
Spear Bio
Biotech
Boston, Massachusetts, USA
37 Employees
Hiring Now

Spear Bio, founded in 2021, is a well-funded and rapidly growing start-up headquartered in Woburn, Massachusetts. Spear Bio’s proprietary technology, Successive Proximity Extension Amplification Reaction (SPEAR), employs a unique 2-factor authentication mechanism to precisely measure protein biomarkers at attomolar levels from sub-microliter sample volumes, enabling unprecedented sensitivity. We are dedicated to revolutionizing early disease diagnosis and monitoring, empowering clinicians and...

Spear Bio
Alloy Therapeutics, Inc.
Boston, Massachusetts, USA
106 Employees
Hiring Now

Alloy Therapeutics is a biotechnology ecosystem company empowering the global scientific community to make better medicines together. Through a community of partners, we democratize access to tools, technologies, services, and company creation capabilities that are foundational for discovering and developing therapeutic biologics. We provide affordable, non-exclusive access to the entire drug discovery community from academic scientists, small and medium biotech,...

Alloy Therapeutics, Inc.
BioPharma Consulting JAD Group
Biotech • Pharmaceutical
Cambridge, Massachusetts, USA
39 Employees
Hiring Now

BioPharma Consulting JAD Group provides a complete portfolio of technical support and solutions for the FDA regulated industry. We deliver solutions with a flexible cost effective approach to meet your company’s needs. BPC JAD group is a company created to help our customers bridge the gap between their business strategy and results. Our mission is to help our clients succeed by...

BioPharma Consulting JAD Group
Flare Therapeutics
Cambridge, Massachusetts, USA
41 Employees
Hiring Now

Our team ‘brings it’ every day for one mission: to conquer transcription factors and create cutting-edge medicines for patients. Flare is lighting up a new therapeutic space with an entirely different approach to decipher the biology of transcription factors to develop small molecule medicines. Based on insights from the seminal work of our scientific founders, Flare’s team is leveraging the power...

Flare Therapeutics
eGenesis
Biotech
Cambridge, Massachusetts, USA
97 Employees
Hiring Now

eGenesis is revolutionizing the field of transplantation with an unparalleled, multiplexed gene editing platform for the development of human-compatible organs, tissues and cells. Harnessing the latest gene-editing techniques, eGenesis has the capability to solve the global organ crisis by providing an alternative to allotransplantation. eGenesis is uniquely positioned to reinvigorate the field of xenotransplantation by addressing both the key virology...

eGenesis
Cullinan Oncology
Cambridge, Massachusetts, USA
88 Employees
Hiring Now

Cullinan Oncology is dedicated to creating new standards of care for patients with cancer. We innovate without borders to find the most promising clinic-ready cancer therapies, whether from our own discovery efforts or through exceptional engagement with our academic and industry partners. Anchored in a deep understanding of immuno-oncology and translational cancer medicine, we leverage our scientific excellence in small molecules and...

Cullinan Oncology
SENDA Biosciences
Cambridge, Massachusetts, USA
102 Employees
Hiring Now

Senda Biosciences, Inc. is uniquely positioned to transform human health by harnessing millions of years of evolution to program targeted, potent and tunable medicines. Nature has provided the codes to program human cells – both within the cell (mRNA), and, remarkably, to the cell - using what surrounds it. The trillions of non-human cells in the human ecosystem have evolved...

SENDA Biosciences
Pulmovant
Software • Biotech
Waltham, Massachusetts, USA
48 Employees
Hiring Now

Pulmovant is a clinical-stage biotechnology company committed to transforming the lives of patients with pulmonary diseases and is a Roivant (Nasdaq: ROIV) company. Pulmovant’s first investigational candidate, mosliciguat, is designed to provide a novel, once-daily, inhaled treatment option for patients with pulmonary hypertension associated with Interstitial Lung Disease (PH-ILD). Mosliciguat is a potential first-in-class soluble guanylate cyclase activator with a...

Pulmovant
Dyno Therapeutics
Watertown, Massachusetts, USA
96 Employees
Hiring Now

Dyno Therapeutics is a Cambridge based, VC-backed biotech startup that uses next-gen DNA technologies and machine learning to engineer Adeno-associated Virus (AAV) capsids for effective delivery of gene therapies

Dyno Therapeutics

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