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Top Massachusetts Biotech Startups (226)

Click Therapeutics
Healthtech • Biotech • App development
We deliver safe and effective digital treatments to patients in need.

Click Therapeutics, Inc., develops, validates, and commercializes software as prescription medical treatments for people with unmet medical needs. As a leading innovator of Digital Therapeutics™, Click delivers accessible, clinically proven, FDA-regulated prescription treatments to the smartphone in your hand. Click’s treatments are defined by a commitment to applying technical and scientific rigor and patient-centric design to the development process. This...

Click Therapeutics
Aura Biosciences
Biotech • Pharmaceutical
Boston
120 Employees
Hiring Now

Aura Biosciences is a clinical-stage biotechnology company focused on developing precision therapies for solid tumors that aim to preserve organ function. Our lead candidate, bel-sar (AU-011), is currently in late-stage development for early choroidal melanoma and in early-stage development in other ocular oncology indications and bladder cancer. Aura Biosciences is headquartered in Boston, MA. Our mission is to grow as...

Aura Biosciences
Kelonia Therapeutics
Biotech • Pharmaceutical
Boston
62 Employees
Hiring Now

Kelonia is pioneering a new wave of genetic medicines using its next generation gene delivery platform. The company’s simple and elegant cutting-edge in vivo gene delivery technology uses a few potent lentiviral vector-like particles to precisely and efficiently deliver in vivo genetic cargo to the desired target tissue, and only that tissue, every time. With an initial focus on developing...

Kelonia Therapeutics
Genomics
Biotech
4 Offices
164 Employees
Hiring Now

We are a pioneering healthcare company that aims to transform health through the power of genomics. The company was formed in 2014 by four world-leading statistical and human geneticists at the University of Oxford, including Professor Sir Peter Donnelly and Professor Gil McVean. We use large-scale genetic information to realise preventative medicine and improve drug discovery. We're a world-leader in...

Genomics
Pulmovant
Software • Biotech
Waltham
48 Employees
Hiring Now

Pulmovant is a clinical-stage biotechnology company committed to transforming the lives of patients with pulmonary diseases and is a Roivant (Nasdaq: ROIV) company. Pulmovant’s first investigational candidate, mosliciguat, is designed to provide a novel, once-daily, inhaled treatment option for patients with pulmonary hypertension associated with Interstitial Lung Disease (PH-ILD). Mosliciguat is a potential first-in-class soluble guanylate cyclase activator with a...

Pulmovant
Dianthus Therapeutics
Waltham
34 Employees
Hiring Now

Dianthus is a biotechnology company dedicated to designing and delivering the next generation of best-in-class monoclonal antibodies with improved selectivity and potency. Led by a multidisciplinary team of seasoned biotech entrepreneurs and scientists, we are pioneering selective antibodies of validated and emerging complement targets to allow people with rare and severe autoimmune diseases live healthier lives to their fullest potential.

Dianthus Therapeutics
Invivyd
Biotech • Pharmaceutical
Waltham
96 Employees
Hiring Now

Invivyd is a biopharmaceutical company on a mission to rapidly and perpetually deliver antibody-based therapies that protect vulnerable people from the devastating consequences of circulating viral threats, beginning with SARS-CoV-2. ​​Invivyd’s technology works at the intersection of evolutionary virology, predictive modeling, and antibody engineering, and is designed to identify high-quality, long-lasting antibodies with the potential to resist viral escape. The...

Invivyd
Atavistik Bio
Cambridge
28 Employees
Hiring Now

Atavistik Bio is a new, privately-held biopharmaceutical company focused on the discovery and development of novel therapies for metabolic diseases and cancer. Our high-throughput platform for the unbiased identification of metabolite-protein interactions will enable the discovery of first-in-class drugs inspired and empowered by nature’s own mechanisms of allosteric control. Our unique approach marries this validated platform with structure-aided drug design...

Atavistik Bio
eGenesis
Biotech
Cambridge
97 Employees
Hiring Now

eGenesis is revolutionizing the field of transplantation with an unparalleled, multiplexed gene editing platform for the development of human-compatible organs, tissues and cells. Harnessing the latest gene-editing techniques, eGenesis has the capability to solve the global organ crisis by providing an alternative to allotransplantation. eGenesis is uniquely positioned to reinvigorate the field of xenotransplantation by addressing both the key virology...

eGenesis
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Dyno Therapeutics
Watertown
96 Employees
Hiring Now

Dyno Therapeutics is a Cambridge based, VC-backed biotech startup that uses next-gen DNA technologies and machine learning to engineer Adeno-associated Virus (AAV) capsids for effective delivery of gene therapies

Dyno Therapeutics
Adams Clinical
Watertown
182 Employees
Hiring Now

Adams Clinical is a network of 6 clinical research sites throughout the US that studies how well medicines treat Psychiatric and Neurological conditions.

Adams Clinical
2020 Onsite
Healthtech • Biotech
Boston
64 Employees
Hiring Now
Quality Ocular Endpoint Protection Through Point-of-Need Ophthalmic Assessments for Clinical Trials

2020 Onsite (also known as 20/20 Onsite) is the only provider solely dedicated to point-of-need eye assessments for clinical trials, proven to meet screening timelines, improve retention rates, and fast-track trials. With over 85,000 eye exams performed, support for 45 clinical trials, and an average of 11+ years of ophthalmic expertise per clinical employee, 20/20 Onsite delivers unmatched mobile ophthalmic experience...

2020 Onsite
Keros Therapeutics
Healthtech • Biotech • Pharmaceutical
Lexington
150 Employees
Hiring Now

Keros is a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization of novel treatments for patients suffering from rare hematologic and musculoskeletal disorders with high unmet medical need

Keros Therapeutics
Remix Therapeutics
Cambridge
62 Employees
Hiring Now

Remix Therapeutics is a biotechnology company developing novel small molecule therapies designed to reprogram RNA processing and treat disease in entirely new ways.

Remix Therapeutics
Praxis Precision Medicines, Inc.
Healthtech • Biotech
Boston
160 Employees
Hiring Now
The era of genetic neuroscience has arrived

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. Praxis is applying insights into the genetic mutations that drive excitation-inhibition imbalance in diseases to select biological targets for rare and more prevalent neurological disorders. We share a common vision of reshaping the human condition into...

Praxis Precision Medicines, Inc.
Naveris
Biotech
Natick
50 Employees
Hiring Now

Our mission at NAVERIS is to deliver innovations in technology with the potential to transform cancer detection, drug development, and clinical trials. Early detection of malignant cancers is critical to ensuring that tumors can be effectively treated with a favorable prognosis for patients. To this end, we are developing several related technologies with the potential to offer highly sensitive and specific...

Naveris
Labviva
Information Technology • Biotech
Boston
65 Employees
Hiring Now

Revolutionizing life sciences procurement. AI-powered digital purchasing platform for complete transparency into your supply chain Labviva integrates with your existing purchasing software to provide you with actionable insights to make better decisions. Keep your current suppliers, contract pricing, and your purchasing software and processes. Our digital marketplace offers unparalleled visibility into your procurement process, to empower informed decisions to drive...

Labviva
Sail Biomedicines
Artificial Intelligence • Healthtech • Biotech
Somerville
122 Employees
Hiring Now

We work at the frontier of programmable medicines. We power our bioplatform and product candidates by harnessing evolution and AI. We operate with purpose and urgency on behalf of people everywhere. We aim to generate life-changing impact for the world

Sail Biomedicines
Nabla Bio
Artificial Intelligence • Software • Biotech
Cambridge
22 Employees
Hiring Now

We develop AI and wet-lab technologies that enable the rational design of developable, selective, and functional drugs against previously undruggable targets. To maximize the patient impact of our platform, we collaborate with leading pharmaceutical companies, including AstraZeneca, Bristol Myers Squibb and Takeda, to expand their pipelines with high-quality drug candidates. If successful we could double the number of disease-relevant drug targets...

Nabla Bio
Scholar Rock
Healthtech • Information Technology • Biotech • Pharmaceutical
Cambridge
187 Employees
Hiring Now

Scholar Rock is a biopharmaceutical company that discovers, develops, and delivers life-changing therapies for people with serious diseases that have high unmet need. As a global leader in the biology of the transforming growth factor beta (TGFβ) superfamily of cell proteins and named for the visual resemblance of a scholar rock to protein structures, the clinical-stage company is focused on...

Scholar Rock

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