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Top Massachusetts Biotech Startups (210)

Click Therapeutics
Healthtech • Biotech • App development
We deliver safe and effective digital treatments to patients in need.

Click Therapeutics, Inc., develops, validates, and commercializes software as prescription medical treatments for people with unmet medical needs. As a leading innovator of Digital Therapeutics™, Click delivers accessible, clinically proven, FDA-regulated prescription treatments to the smartphone in your hand. Click’s treatments are defined by a commitment to applying technical and scientific rigor and patient-centric design to the development process. This...

Click Therapeutics
Conagen
Biotech
Bedford, Massachusetts, USA
61 Employees

Conagen is an accomplished biotechnology company located in the greater Boston biotech corridor. We innovate and develop synthetic biology solutions for supporting global partners across a spectrum of current and developing markets. From our proprietary strain development to fermentation and process scale-up, Conagen impacts partners’ abilities to sell and market products in the food, nutrition, flavor and fragrance, pharmaceutical, and...

Conagen
REGENHU
3D Printing • Other • Biotech
Boston, Massachusetts, USA
35 Employees

REGENHU is a provider of 3D Bioprinters, and has developed, manufactured and distributed innovative hardware and software tools for 3D Bioprinting applications since 2007. We are a pioneer in the field and our global customer portfolio comprises leading universities as well as key players in the biotech industry, pharma, cosmetics, and MedTech. We are rapidly expanding our world class team of...

REGENHU
MOMA Therapeutics
Boston, Massachusetts, USA
69 Employees

We’re on a mission to unlock molecular machines by understanding and respecting their complexities. We’ll be working incredibly hard to discover their untapped potential because we believe they are the key to delivering the next generation of precision medicines. We are unapologetically scientific, and we know this will help us achieve our mission to get new medicines to people in...

MOMA Therapeutics
Ark Biotech
Software • Biotech
Boston, Massachusetts, USA
10 Employees
6 Benefits
Bioreactor simulation software to get life-saving medicine to market faster

At Ark, we are transforming bioprocessing by championing a model-first approach that combines biology, chemistry, and physics with the predictive power of machine learning and AI. By replacing traditional trial-and-error methods with hybrid models, we empower organizations to predict outcomes, optimize processes, and scale with precision—dramatically reducing R&D timelines, cutting costs, and increasing accessibility to life-saving therapies and innovative products....

Ark Biotech
Scorpion Therapeutics
2 Offices
90 Employees

Scorpion Therapeutics was founded to expand the reach of precision medicine to more people with cancer. The company is integrating cutting-edge technologies across target discovery, medicinal chemistry, and translational medicine to deliver Precision Oncology 2.0, a pipeline of targeted small-molecule drugs that overcome the limitations of existing treatments. Scorpion’s experienced leadership team is executing a fit-to-purpose model to efficiently unlock...

Scorpion Therapeutics
FogPharma
Healthtech • Biotech • Pharmaceutical
Cambridge, Massachusetts, USA
141 Employees

FogPharma is developing a new class of drugs to address the limitations of today’s precision medicines and achieve universal druggability. The company is pioneering the discovery, development and commercialization of HeliconTM peptides, a new drug modality that uniquely combines the broad targeting power of monoclonal antibodies with the cell-penetrating ability of small molecules. HeliconTM peptides hold the promise, not only...

FogPharma
Beaconcure
Artificial Intelligence • Machine Learning • Software • Biotech • Pharmaceutical
2 Offices
40 Employees

Beaconcure supports biopharmaceutical companies and CROs with Verify, a secure online workspace for AI-enabled clinical study analysis validation. Designed in partnership with trusted large pharmaceutical companies and used in an increasing number of approved products, Verify streamlines validation workflows, reduces error rates, and increases efficiency compared to traditional processes. Beaconcure is revolutionizing the way new drugs and vaccines are approved for...

Beaconcure
Parallel Bio
Biotech
Cambridge, Massachusetts, USA
7 Employees

Parallel Bio created a human 'immune system in a dish' to discover drugs and immunotherapies more likely to work in patients.

Parallel Bio
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Genialis
Biotech
Boston, Massachusetts, USA
29 Employees

Genialis is a computational precision medicines company unravelling complex biology to find new ways to address disease. ResponderID™, Genialis’ clinical biomarker discovery platform, defines, models, and validates actionable biomarkers and optimally positions novel drugs to accelerate translational research and clinical development. Genialis is trusted by biopharma and big pharma alike, and together, we bring precision to medicine.

Genialis
Anodyne Nanotech, Inc
Boston, Massachusetts, USA
16 Employees

Anodyne Nanotech, Inc. is a preclinical-stage biotech company developing differentiated, transdermal forms of high-value drugs. The company’s macroporous microneedle technology provides the first practical and cost-effective platform, Hero Patch, to deliver clinically meaningful doses of macromolecules such as monoclonal antibodies or small molecules (such as ibuprofen) for fast and sustained delivery. We pride ourselves on providing a painless experience for...

Anodyne Nanotech, Inc
Reverie Labs
Healthtech • Machine Learning • Biotech • Pharmaceutical
Cambridge, Massachusetts, USA
25 Employees
33 Benefits
Reverie Labs places computation, chemistry, and creativity at the center of drug discovery.

Reverie Labs is a pharmaceutical company that uses its innovative computational chemistry and machine learning tools to accelerate its drug discovery programs. Reverie's primary goal is to develop kinase inhibitors that address the unmet needs of patients.

Reverie Labs
Orionis Biosciences
Waltham, Massachusetts, USA
43 Employees

Orionis Biosciences is a life sciences company pioneering technological innovation in genome-scale drug discovery and tunable molecular design of novel therapeutic drug modalities. Our technologies and pipeline include proprietary A-Kine™ biologics and Allo-Glue™ small molecule platforms with broad, innovative applications to the reprogramming of disease states. The company is currently advancing multiple novel immunotherapies for the treatment of cancer.

Orionis Biosciences
Elektrofi
Biotech
Boston, Massachusetts, USA
38 Employees

Elektrofi is a biotechnology company focused on improving administration for a wide range of medicines including monoclonal antibodies, therapeutic proteins, and other large molecule drugs. Its breakthrough formulation platform enables stabilized, highly concentrated formulations for subcutaneous administration. The company is using this technology to transform therapies that are administered intravenously, and to enhance injectable products by reducing the volume and...

Elektrofi
Allonnia
Biotech
Boston, Massachusetts, USA
35 Employees

Allonnia is a bio-ingenuity company™ dedicated to extracting value where others see waste. We believe that elegant solutions to the world’s biggest problems will be found in the world’s smallest organisms. So, we’re pioneering novel approaches and imaginative combinations in biotechnology and engineering to solve waste challenges in nature, using nature. We are focused on three key sectors of mining, industry,...

Allonnia
Matchpoint Therapeutics
Cambridge, Massachusetts, USA
27 Employees

Matchpoint is a biotechnology company harnessing the power of covalency to discover precision covalent medicines to transform the treatment of immune diseases and other serious illnesses. The company's proprietary Advanced Covalent Exploration (ACE) platform integrates advanced chemoproteomics, machine learning and covalent chemistry library evolution. Matchpoint has an emerging pipeline of novel covalent medicines initially focused on immunology. For more information,...

Matchpoint Therapeutics
Nested Therapeutics
Cambridge, Massachusetts, USA
39 Employees

We are Nested Therapeutics, a biotech company inspired by service and driven by a desire to make a meaningful impact. We are creative innovators who challenge our own assumptions as we strive to find new, overlooked areas of opportunity to design therapeutics for a perfect fit. We embrace diverse perspectives and experiences in a space for everyone to add value...

Nested Therapeutics
Fortis Life Sciences
Boston, Massachusetts, USA
122 Employees

Fortis partners with diagnostics and life sciences companies to design, validate, and manufacture solutions to solve their complex development problems. Fortis’ tailored approach and end-to-end capabilities accelerate the work of its customers as they bring the next generation of medicines and diagnostics to market. Fortis serves a global customer base and has offices across the world including four R&D sites...

Fortis Life Sciences
Voyager Therapeutics
Cambridge, Massachusetts, USA
131 Employees
Hiring Now

We are Voyager Therapeutics, a pre-clinical stage biotech compelled by curiosity and powered by persistence. Voyagers are bold innovators who are energized in unlocking the full potential of AAV gene therapy employing our TRACER™ capsid discovery platform. Our resolve is to advance the field of AAV gene therapy, and through our innovative capsids, we are extending the reach and impact...

Voyager Therapeutics
Matterworks
Big Data • Machine Learning • Software • Analytics • Biotech
Somerville, Massachusetts, USA
25 Employees
15 Benefits Hiring Now
AI-Powered Tools to Engineer Biology

Matterworks is developing advanced AI-powered software and proprietary chemistry reagents to enable real-time, quantitative metabolomics to accelerate the research, development, and manufacturing of biologic therapeutics. Metabolomics measures all the small molecules a cell needs to function. In spite of its far-reaching potential impact across life science disciplines, adoption of metabolomics remains limited and lags behind other ‘omic techniques due to a...

Matterworks

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