Top Remote Python Jobs in Washington, DC

Build and maintain end-to-end web applications powering sales and operations. Design tools for quoting, scheduling, and fulfillment, integrate AI into products, collaborate on UX, ship high-impact features, and contribute to architecture, deployment, and engineering culture.

Own and operate core corporate IT systems including identity, endpoints, cloud infrastructure, and automations. Administer AWS, ServiceNow, MDM, and SaaS integrations; build workflows, govern AI tools, handle Tier 3 incidents and on-call duties, and partner with Security, People, and Enterprise apps to ensure reliability, security, and compliance.

Develop, design, and maintain production software for autonomous mission management of a satellite constellation. Contribute to architecture, implement scalable algorithms in Python and Go, support production operations, on-call rotations, launches, and cross-team integration for automated constellation operations.

Design, build, and operate scalable AWS-based platform infrastructure for data processing. Improve pipeline automation, monitoring, security, and reliability. Lead CI/CD, IaC (Terraform/Scalr), network design, and incident response; collaborate with cross-functional teams and participate in on-call rotation. Integrate AI tools to streamline development and troubleshooting.

Design, provision, and manage cloud infrastructure using IaC (Terraform/Pulumi). Build and optimize Docker containers, CI/CD pipelines, container compute (EKS/GKE/ECS/Fargate/Cloud Run), serverless functions, networking, storage, and databases. Implement cloud security and compliance controls, automate operations with code (Go/Python/Node.js/Bash), and ensure monitoring and high uptime while working independently with cross-functional teams and clients.

Senior technical authority for IBM AIX and Power Systems architecture, engineering, migration, performance tuning, automation, and resiliency. Lead large-scale OS and hardware migrations, own lifecycle management, incident escalation/RCA, HA/DR design, and mentor L3 engineers while ensuring governance, compliance, and vendor coordination.

Design, build, and manage data pipelines, integrations, ML and rules-based classification, and applications. Collaborate with data scientists and cross-functional Scrum teams, drive technical strategy, innovate practices, and mentor junior engineers.

Build and scale secure, high-performance backend systems and APIs that connect onchain protocols and offchain infrastructure. Own integrations with custodians, KYC/identity, payments, and third-party blockchain tooling. Collaborate with smart contract and frontend teams, enforce backend standards, and support ops, investor services, and compliance with automation and observability tooling.

Design, build, and maintain a modern AWS-based data lake/lakehouse and ETL/ELT pipelines ingesting Qualtrics, HubSpot, archival and external datasets. Implement data harmonization, governance, quality, and monitoring. Enable AI/LLM and agentic workflows, support analytics and Qlik integrations, document data assets, and collaborate across teams to produce insights, dashboards, and data products.

Develop and deploy options pricing and execution models for digital asset derivatives. Research volatility dynamics and microstructure, build backtests handling path dependency and costs, design hedging and delta management, collaborate with engineers to move strategies into live infrastructure, and monitor real-time Greeks and P&L to iterate on models.

Lead design, architecture, and hands-on implementation of scalable healthcare SaaS systems. Drive interoperability (HL7, FHIR, EDI), mentor engineers, liaise with stakeholders, manage technical risk, and ensure quality, performance, security, and innovation.

Lead test strategy within sprint teams, design and maintain automated API and UI tests and frameworks, create test plans and metrics, find and track defects, and improve CI/CD, security, and performance testing using automation and AI tools.

The Software Engineer II will develop backend services and APIs while also contributing to frontend React components, focusing on digital services for federal clients.

Engineer software that connects AI-driven platforms to datacenter power infrastructure. Develop control strategies and optimize energy use and AI workloads.

The Senior Technology Site Reliability Engineer is responsible for maintaining and optimizing infrastructure and applications, ensuring reliability and performance while automating processes and collaborating with teams.

Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.

Build and maintain scalable backend systems and data pipelines for healthcare workflows. Collaborate cross-functionally to automate provider and patient workflows, prototype features, ship production-ready code, and ensure systems are maintainable and scalable.

Design and build scalable backend systems, data pipelines, and cloud infrastructure. Own CI/CD, containerization, databases, and reliability; collaborate with tech leads to deliver secure, production-grade solutions for startups in a fully remote environment.

Build and optimize high-throughput de-identification pipelines for large clinical datasets, execute QA, run and tune pipelines in health system cloud environments, reduce errors and costs, and collaborate with privacy and clinical informatics stakeholders.

Join as a full-stack software engineer to design, develop, and maintain web applications and services. Collaborate cross-functionally, write clean code, perform code reviews, debug issues, and stay current with industry trends.

We are seeking a Software Engineer with 1-3 years of experience to join our technology enablement program and focus on Zoho technologies. The role involves designing and implementing digital transformation solutions, requires technical and soft skills, and offers hands-on training and client-facing work.

Manage and optimize large-scale Ubuntu and RHEL servers, perform upgrades, patching, performance tuning, security hardening, backups and disaster recovery. Maintain configuration management and deployment pipelines (Ansible/Puppet/Terraform), monitor system health, troubleshoot OS/hardware/network issues, collaborate with DevOps/Cloud teams for provisioning, and produce documentation, SOPs, and audit reports.

As a Backend Engineer, design and manage backend infrastructure, develop microservices, optimize data systems, collaborate with teams, and participate in on-call rotations.

Design high-performance C++ libraries for automated PCB design challenges, mentoring peers and shaping technical direction while collaborating with experts in various fields.

Design and build AI-powered backend services, optimizing performance and scalability while collaborating with cross-functional teams to integrate generative AI models.