Top Remote Machine Learning Jobs in San Luis Obispo, CA

Leads complex AI client projects from requirements gathering through delivery, serving as the primary client contact and coordinating Sales, Operations, Product, and Engineering. Responsibilities include defining scopes and delivery plans, managing risks, quality, timelines, budgets, profitability, and KPIs, resolving execution challenges, and improving scalable processes for AI project delivery.

Develops and productionizes deep learning and machine learning perception models for robotics and recycling sortation. Responsibilities include experimenting with neural network architectures, designing computer vision solutions, conducting statistical experiments, deploying successful models, collaborating with data, modeling, and cloud infrastructure teams, and improving ML infrastructure.

Analyze and characterize conversational audio data, identify underrepresented areas, and build active-learning and human-in-the-loop workflows. Develop representative benchmarks, automate model adaptation, and create reusable data analysis and scoring systems. Partner with research, engineering, and data teams to run experiments, improve models, organize data, and translate complex findings into measurable product improvements.

Develops, calibrates, validates, and maintains credit risk models, including PD, LGD, and EAD models, for lending, collections, loss forecasting, capital planning, and stress testing. Analyzes large datasets, evaluates model performance, documents model changes, supports systems testing, and communicates statistical insights to stakeholders and management. Collaborates across the credit union to improve risk-return strategies and reporting.

Leads Lyra Health’s AI/ML engineering roadmap, scales and mentors machine learning teams, and drives production-grade systems for clinical applications. Responsibilities include people leadership, quarterly planning, technical architecture, design reviews, model governance, ML SDLC oversight, and deployment of reliable microservices on Kubernetes. The role partners with product, data science, and clinical stakeholders while ensuring safety, operational excellence, cloud scalability, and compliance for sensitive healthcare data.

Leads complex enterprise SaaS delivery programs for major banks, owning governance, client and executive relationships, commercial controls, risk management, regulatory deadlines, third-party coordination, and successful go-live. The role requires deep financial crime compliance technology experience, including AML, KYC, transaction monitoring, sanctions screening, or case management platforms, plus proven Tier 1 bank implementations, program turnaround expertise, cloud delivery, and senior stakeholder credibility.

Lead independent validation and ongoing monitoring of complex financial and analytics models, including ALM, loss forecasting, loan transition, corporate finance, and engagement models. Identify weaknesses, communicate findings, guide remediation, and strengthen model governance. Collaborate with Finance, Quantitative Research, Growth Analytics, Internal Audit, Internal Controls, Accounting, and Compliance to maintain Affirm’s model risk framework and address audit, regulatory, and examiner requests.

Leads Tala’s Machine Learning Engineering team in building and operating platforms for model development, real-time inference, streaming features, batch processing, deployment, monitoring, and production reliability. Manages and develops 4–6 engineers, owns delivery and prioritization, provides architectural leadership, improves engineering practices and SLOs, and partners with Data Science, Data Engineering, Product, Credit, and Business Development teams.

Leads enterprise innovation strategy and cross-domain solution architecture across AI, data, cloud, software engineering, ITSM, DevSecOps, and cybersecurity. Designs scalable, secure solutions; develops reusable accelerators and innovation frameworks; supports federal proposals, capture efforts, and technical writing; advises senior government stakeholders; and drives cross-functional collaboration, capability development, and technology adoption in GovCon environments.

Sell Omnifold’s AI-driven forecasting and optimization platform to enterprise customers across supply chain, manufacturing, CPG, retail, and logistics. Responsibilities include self-sourcing pipeline, engaging senior executives, managing complex multi-stakeholder sales cycles, quantifying ROI, closing six- and seven-figure deals, maintaining CRM accuracy, forecasting, and helping build the company’s sales playbook and go-to-market strategy.

Develop and lead data science and machine learning initiatives, including exploratory analysis, predictive modeling, experimentation, recommendation systems, user classification, model monitoring, and production deployment. Partner with product, marketing, analytics, and engineering teams to convert user insights into automated services. Manage projects throughout their lifecycle, support strategic ML planning, and deliver solutions for personalization, cross-selling, and retargeting.

Consult as a fractional data scientist for hedge funds, private equity firms, and family offices. Lead data science initiatives: build infrastructure, develop and deploy models, create portfolio dashboards, monitor post-deployment performance, and partner with investment teams to turn data into actionable investment insights. Advise on vendor selection, data quality, technology stacks, KPIs, and governance.

Lead positioning, messaging, go-to-market strategy, launches, channel enablement, competitive intelligence, and analyst relations for Sophos’ AI cybersecurity solutions. Translate complex technical capabilities into buyer- and partner-focused narratives, build launch assets and sales tools, and coordinate cross-functional execution across product, sales, marketing, and research teams. The role also develops customer feedback loops, competitive battlecards, and category-defining market perspectives.

Lead load and generation interconnection studies, including steady-state, short-circuit, and dynamic analyses. Develop power-flow and stability models, establish study methodologies, evaluate system upgrades and grid-enhancing technologies, and present recommendations to utilities, developers, regulators, and customers. Serve as a power systems subject-matter expert, help connect planning assessments with utility operations, and collaborate with AI and automation teams to improve study efficiency and accuracy.

Leads enterprise data, analytics, business intelligence, and AI strategy across healthcare payer functions. Partners with executives to prioritize analytics initiatives, build reporting and predictive insight capabilities, establish data governance and accountability, and drive measurable business outcomes. Oversees cross-functional teams, enterprise application development, Azure architecture, quality automation, DevOps, and intelligent automation while engaging C-suite and board stakeholders.

Leads the development of partner enablement programs for Databricks and Snowflake ecosystems. Establishes strategies, governance, stakeholder relationships, learning pathways, workshops, bootcamps, champion networks, and readiness frameworks for technical and business audiences. Translates data, AI, analytics, and lakehouse use cases into scalable learning experiences, aligns programs with partnership growth objectives, measures engagement and effectiveness, and continuously improves initiatives based on partner feedback and business impact.

The Enterprise Account Executive will drive revenue growth by managing complex sales cycles, closing deals with Fortune 500 companies, and understanding both technical and business needs.

Leads complex technical programs supporting government and defense missions, managing scope, schedules, budgets, risks, customer relationships, and multidisciplinary teams. Provides technical direction across software development, cloud architecture, data engineering, operations research, analytics, and decision support. Oversees modeling, optimization, machine learning, dashboards, and executive recommendations while engaging senior government stakeholders. Supports proposals, capture activities, technical reviews, and continuous improvement initiatives.

Leads business insights and analytics for Rocket Pharma’s gene therapy portfolio, with emphasis on rare cardiology. Responsibilities include disease modeling, patient-identification analytics, forecasting, market research, real-world data integration, analytics platform development, and market-development strategy. The role partners cross-functionally with IT, vendors, field teams, and external analytics providers while translating fragmented data into strategic recommendations and ensuring compliant use of analytics and market research investments.

Partner with healthcare clients to design, prototype, and deploy production-grade AI/LLM solutions. Lead discovery, architecture, cloud integration, and delivery while troubleshooting distributed systems and driving measurable client outcomes.

Design, develop, and evaluate large-scale multimodal foundation models for biological research. Build hybrid LLM and graph neural network architectures, relational foundation models, and distributed multi-GPU training systems. Apply deep learning theory to biological data, transition research prototypes into scalable production systems, publish peer-reviewed research, and mentor junior staff while collaborating across scientific and engineering teams.

Build and deploy scalable AI and machine learning products for clinical research, including patient recruitment, enrollment forecasting, and study feasibility. Develop ML models, LLM-powered agents, data pipelines, and MLOps infrastructure using cloud services and CI/CD automation. Collaborate with cross-functional teams to integrate AI into clinical research workflows, monitor model performance, and advance reliable, unbiased solutions that improve patient outcomes.

Leads Yahoo’s Detection Engineering team within Threat Detection and Response. Responsibilities include developing cybersecurity detection strategy, managing detection engineers, building and maintaining detection rules, supporting investigations, conducting threat hunting and purple-team activities, integrating threat intelligence, and applying data science and AI to identify adversaries. The role also guides sprint delivery, researches emerging threats, and collaborates with security leadership, incident response, insider threat, and advanced cyber threat teams.

Own and prioritize the product backlog, facilitate Agile ceremonies, write user stories and functional specifications, define acceptance criteria, and align engineering, design, and stakeholders. The Product Owner tracks delivery progress, oversees testing and validation, incorporates user feedback and performance metrics, and improves team workflows through clear documentation and proactive communication.

The Senior Data Scientist will analyze large-scale customer data, investigate behavioral questions, design and automate studies, and translate findings into actionable recommendations. The role includes maintaining analytics frameworks, documenting methodologies, writing white papers, and communicating insights across the company. Candidates should be independent, comfortable with ambiguity, and experienced with SQL and Redshift. Python or R, machine learning, Spark, A/B testing, and cross-functional experience are preferred.