Top Remote Python Jobs in San Diego, CA

Lead the technical vision for complex systems, drive architectural strategies, write production-ready code, and align teams for public sector compliance.

As a Software & Data Engineer, you will design data pipelines, deploy AI tools, build data warehouses, and integrate systems for clients, ensuring data quality and performance.

You will manage AWS infrastructure, automate deployments, debug application issues, and improve the operational health of Metabase Cloud.

Design, build, operate, and evolve backend services and runtime infrastructure for cloud orchestration and job execution. Own distributed, asynchronous systems, APIs, workers, persistence, and service-to-service coordination. Improve reliability, observability, testing, and operational tooling; lead cross-team designs and mentor engineers.

Join a remote Strategic Projects engineering team to turn AI-native prototypes into production-grade services. You will harden demos (LLM gateways, proxies, sandboxes), implement observability, error handling, and security practices, work with reference customers on integrations, and ensure agent-generated code meets production review and operational standards.

Build full-stack features for AI voice and chat products using TypeScript, Node.js, React, and Python. Integrate ASR/TTS and LLM improvements, optimize production systems for latency and cost, participate in on-call rotations, and collaborate with ML and product teams to scale enterprise AI conversations.

Develop high-fidelity RGB and LWIR camera models and synthetic-data pipelines in Unreal Engine, stream sensor outputs to ROS 2, implement noise/artifacts and target injection, manage 3D asset pipelines, and optimize headless/real-time simulation for perception and Target State Estimation testing and CI/CD integration.

Lead platforms engineering for scalable cloud infrastructure: design and implement Kubernetes-based systems, optimize data pipelines with AI, refactor stateful services to be stateless, improve autoscaling and reliability, own data ingestion/export, build internal developer tools, enforce security and testing standards, mentor engineers, and participate in on-call rotations.

Build and own the GTM tech stack and integrations, create demo environments seeded with realistic data, embed AI agents into sales workflows, stand up revenue data infrastructure (pipeline, forecasting, attribution), and automate customer service flows. Partner closely with Sales, Marketing, Customer Success, and Product Engineering to measure adoption and impact.

First dedicated QA hire responsible for test planning, building and maintaining automated test suites across a TypeScript+Python stack, integrating tests into CI/CD, running regression and performance tests, identifying and verifying bugs, improving observability, and documenting QA processes.

Lead design, architecture, and delivery of enterprise web, mobile, backend and cloud solutions. Provide technical and people leadership across Agile teams, enforce engineering best practices (CI/CD, DevSecOps, observability), mentor engineers, manage delivery risks, and drive platform modernization and production readiness.

Lead architectural strategy and modernization for large-scale distributed systems. Design modular, extensible services, migrate legacy monoliths to microservices, optimize AWS infrastructure and costs, document and visualize systems, facilitate cross-functional design, mentor engineering teams, and scout emerging technologies.

Lead design, build, and scale GridUnity's cloud SaaS platform. Own end-to-end features, mentor engineers, drive architecture, improve scalability, reliability, security, and data practices while collaborating with product teams.

Design, develop, and optimize system software and firmware for SoC-based O-RAN infrastructure. Implement power-management policies (DVFS, clock/power gating, thermal control), analyze RU/DU workloads, build performance and power models, create measurement and test tooling, validate on simulation/emulation and silicon, and influence SoC and platform architectures for 5G/6G deployments.

Work on a DevOps/SRE platform team to build and maintain Kubernetes clusters, IaC, CI/CD pipelines, identity management, monitoring, certificate lifecycle, and security compliance. Troubleshoot deployments, support on-call incidents, document runbooks/ADRs, mentor junior engineers, and contribute to strategic platform planning and automation to ensure a reliable, secure, and scalable cloud platform.

As an Automation QA Engineer, you'll design and implement test frameworks for Oracle projects, focusing on automation testing for APIs and web interfaces, collaborating with development teams to identify and resolve defects.

The role involves developing and maintaining Oracle HCM integrations, ensuring the accuracy and security of data flows, and mentoring junior developers.

The Senior Oracle Payroll Integrations Developer will design, develop, and maintain integrations across payroll systems, ensuring data integrity and compliance while optimizing performance and scalability.

Design, automate, deploy, and operate large-scale software-defined storage and Kubernetes platforms in a private cloud. Build IaC and GitOps workflows (Ansible, Terraform, Helm, Git), implement CI/CD for infra, manage backups, monitoring, and observability, troubleshoot cross-domain issues, participate in on-call/incident response, and produce runbooks and documentation.

Design, implement, and operate large-scale DNS and multi-tenant Kubernetes infrastructure in private cloud. Automate provisioning with IaC (Ansible, Terraform/Pulumi, Python), build CI/CD and GitOps pipelines, implement monitoring/alerting (Prometheus/Loki/Grafana), harden for HA and DR, perform deep troubleshooting across storage, hypervisors and networking, participate in on-call incident response, and collaborate on change management with global teams.

Operate and lead data-center LAN infrastructure in a 24/7 SaaS environment. Own troubleshooting, incident response, and change management across Cisco Nexus, Palo Alto, and F5 platforms. Drive projects, architecture (VXLAN/EVPN), automation (Ansible, Terraform, Python), observability (Prometheus, Grafana, SolarWinds), and cloud networking (AWS, GCP). Mentor junior engineers, participate in on-call rotation, and define operational standards, reliability metrics (SLI/SLO), and preventive engineering.

Architect, implement, and operate a multi-tenant OpenStack private cloud. Automate provisioning with Ansible/Terraform/Pulumi, extend core OpenStack services, build CI/CD update pipelines, implement monitoring/observability, harden for HA and DR, perform deep troubleshooting, and participate in on-call incident response and upstream contributions.

Design, build, and maintain full‑stack features across frontend (TypeScript + React) and backend (Python, Node.js, or JVM languages). Own end-to-end development, testing, CI, databases, and cloud/distributed systems. Mentor engineers, participate in code reviews and pair programming, and work in an agile, remote team.

Senior full-stack engineer responsible for designing and building end-to-end features across frontend (TypeScript + React) and backend (JVM languages, Python/Node.js). Owns code quality, testing, CI, and collaborates in agile teams. Mentors junior engineers, participates in code reviews and pair-programming, and works with cloud, databases, and distributed systems. Remote role with occasional in-person meetups.

As a Senior Software Engineer at Vanta, you will design and build internal tools for go-to-market teams, focusing on applications that enhance sales and customer engagement, employing modern tech and AI workflows.