Top Remote Python Jobs in San Diego, CA

Reposted 18 Days AgoSaved
Remote
Remote San Diego, CA
Mid level
Mid level
Sales • Software • Design
The Prototype Engineer will integrate AI/ML capabilities into Higharc's products, develop tools for autonomous agents, and collaborate with research and product teams. Responsibilities include pushing prototypes to production and understanding homebuilding complexities.
Top Skills: Ai/MlAPIsCi/CdHuggingfaceLlm ApisPythonPyTorchRag ArchitecturesReactTypescriptVector Databases
Reposted 18 Days AgoSaved
Remote
Remote San Diego, CA
Mid level
Mid level
Information Technology • Consulting
As a Software & Data Engineer, you will design data pipelines, deploy AI tools, build data warehouses, and integrate systems for clients, ensuring data quality and performance.
Top Skills: Ai ToolsAWSAzureBigQueryCircleCIDbtDockerGCPHubspotLookerPower BIPythonRedshiftSalesforceSigmaSnowflakeSQLTerraformZendesk
Reposted 18 Days AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Big Data
You will manage AWS infrastructure, automate deployments, debug application issues, and improve the operational health of Metabase Cloud.
Top Skills: AWSDatadogGoGrafanaKubernetesPrometheusPythonTerraform
Reposted 18 Days AgoSaved
Remote
Remote San Diego, CA
120K-175K Annually
Senior level
120K-175K Annually
Senior level
Big Data • Machine Learning • Software • Analytics
Design, build, operate, and evolve backend services and runtime infrastructure for cloud orchestration and job execution. Own distributed, asynchronous systems, APIs, workers, persistence, and service-to-service coordination. Improve reliability, observability, testing, and operational tooling; lead cross-team designs and mentor engineers.
Top Skills: C++Ci/CdContainersCpython AbiDockerEvent-Driven ArchitectureGitGoGrpcJavaKubernetesMessaging/Queueing SystemsNode.jsNumpyObservability ToolingOpensslPythonRelational DatabasesRest ApisRustTypescriptVenvVirtualenvWix
Reposted 19 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
129K-172K Annually
Senior level
129K-172K Annually
Senior level
Insurance • Real Estate
Design, build, test, and maintain secure, scalable cloud-native full‑stack applications on Azure. Implement APIs, microservices, and AI-enabled features (LLMs, RAG, Azure OpenAI). Apply CI/CD, observability, secure SDLC, and mentor teammates while collaborating with product, architecture, DevOps, and security to deliver production-ready solutions.
Top Skills: Azure Ai ServicesAzure App ServicesAzure DevopsAzure FunctionsAzure OpenaiCi/Cd PipelinesCosmos DbDockerGitGitGitlabJavaScriptKubernetesLinuxLlmsMongoDBMySQLNpmPostgresPythonRagReactRest ApisSQL ServerTypescriptVector DatabasesWindows
19 Days AgoSaved
Remote or Hybrid
Remote San Diego, CA
110K-130K Annually
Senior level
110K-130K Annually
Senior level
Information Technology • Database • Consulting
Design, deploy, automate, and support Cloudera Data Platform clusters and Hadoop ecosystem services. Build Ansible automation and CI/CD for provisioning, configuration, patching, monitoring, security integrations (Kerberos/LDAP/TLS), capacity planning, disaster recovery, and on-call operations to support data ingestion, processing, and analytics workloads.
Top Skills: Active DirectoryAirflowAnsibleBashCentosCloudera Data Platform (Cdp)Cloudera ManagerGitGrafanaHdfsHiveImpalaJenkinsKafkaKerberosLdapOoziePrometheusPythonRhelRole-Based Access ControlSolrSparkSplunkSQLTlsYarn
19 Days AgoSaved
Remote
Remote San Diego, CA
130K-200K Annually
Senior level
130K-200K Annually
Senior level
Software
Design, implement, test, and maintain low-level embedded firmware for ARM Cortex-M systems. Debug hardware/software issues using lab equipment, develop Python host tools, support hardware bring-up, CI/CD and automated testing, resolve manufacturing and field issues, and participate in architecture, code reviews, and documentation.
Top Skills: Arm Cortex-MCCi/CdClangCmakeGccGitI2CJtagLinker ScriptsLinuxLogic AnalyzerMakeOscilloscopeProtocol AnalyzerPytestPythonRaspberry Pi Rp2040Rp2350SpiStatic AnalysisSwdUartUnit TestingUsbUsb-Pd
19 Days AgoSaved
Remote
Remote San Diego, CA
163K-226K Annually
Mid level
163K-226K Annually
Mid level
Software
Join a remote Strategic Projects engineering team to turn AI-native prototypes into production-grade services. You will harden demos (LLM gateways, proxies, sandboxes), implement observability, error handling, and security practices, work with reference customers on integrations, and ensure agent-generated code meets production review and operational standards.
Top Skills: AbacAPIsClaude CodeCoding AgentsCursorGoLlmsMfaNetworkingOauthObservabilityOidcPythonRbacRustSAMLScimTailscaleTypescript
19 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
192K-269K Annually
Senior level
192K-269K Annually
Senior level
Aerospace
Develop and own end-to-end, high-fidelity simulation frameworks for large multi-beam phased-array satellite communication systems. Model digital/hybrid beamforming, array performance, RF impairments, satellite geometry, and link budgets. Perform Monte Carlo and corner-case analysis, generate coverage/SINR maps, evaluate architecture tradeoffs, and translate results into antenna, RF, and digital implementation requirements. Collaborate with cross-functional teams and support correlation with hardware measurements and system testing.
Top Skills: 3Gpp5GAntenna ArraysAsicBeamformingC/C++CudaFpgaGpuMatlabOfdmPhased ArraysPythonRf
19 Days AgoSaved
Remote
Remote San Diego, CA
Mid level
Mid level
Artificial Intelligence • Information Technology • Software
Build and operate an AWS-native data lake and AI gateway. Implement and maintain lakehouse architecture (Iceberg) using Glue, Athena, and S3; manage infrastructure as code (Terraform); run reliable data pipelines; operate LLM gateway/Bedrock; enforce security, IAM, networking, and secrets controls; partner with IT and Security.
Top Skills: Amazon AthenaAmazon BedrockAmazon S3Apache IcebergApi ProxiesAws GlueAws IamAws PrivatelinkInfrastructure-As-CodeLlm GatewayPythonTerraformVpc
19 Days AgoSaved
Remote
Remote San Diego, CA
140K-170K Annually
Mid level
140K-170K Annually
Mid level
Artificial Intelligence • Software • Generative AI • Automation
Operate and harden Blitzy's self-hosted, Kubernetes-based AI platform inside customer-controlled secure cloud environments. Own deployments, upgrades, capacity planning, observability, incident response, and customer-facing technical coordination while championing security and feeding operational learnings back into the product roadmap.
Top Skills: Alerting)BashCloud (Aws/Gcp/Azure)Container OrchestrationGoInfrastructure-As-CodeKubernetesMetricsObservability (LoggingPulumiPythonTerraformTracing
19 Days AgoSaved
Remote
Remote San Diego, CA
130K-190K Annually
Senior level
130K-190K Annually
Senior level
Other
Build full-stack features for AI voice and chat products using TypeScript, Node.js, React, and Python. Integrate ASR/TTS and LLM improvements, optimize production systems for latency and cost, participate in on-call rotations, and collaborate with ML and product teams to scale enterprise AI conversations.
Top Skills: Automatic Speech RecognitionAWSAzureCi/CdConversational AiGCPGoogle Cloud ServicesKubernetesLlm Prompt EngineeringLlmsMetrics Logging MonitoringMySQLNode.jsPostgresPythonReactRustTelephonyText To SpeechTypescript
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19 Days AgoSaved
Remote
Remote San Diego, CA
134K-184K Annually
Senior level
134K-184K Annually
Senior level
Healthtech
Lead the migration from legacy Azure services to a Kubernetes-based, containerized microservices platform. Design, build, and scale infrastructure, implement observability (monitoring/alerting/logging), drive incident response and SLOs, automate with IaC and CI/CD, optimize cost and networking, mentor teams, and document systems to ensure reliable, scalable healthcare platform operations.
Top Skills: .NetAWSAzureAzure Entra IdBashC#DatadogGCPGithub ActionsGitlab Ci/CdGrafanaHelmKubernetesPrometheusPythonTerraform
19 Days AgoSaved
Remote
Remote San Diego, CA
145K-175K Annually
Mid level
145K-175K Annually
Mid level
Aerospace • Defense • Manufacturing
Develop high-fidelity RGB and LWIR camera models and synthetic-data pipelines in Unreal Engine, stream sensor outputs to ROS 2, implement noise/artifacts and target injection, manage 3D asset pipelines, and optimize headless/real-time simulation for perception and Target State Estimation testing and CI/CD integration.
Top Skills: BlenderBlueprintC++Ci/CdCompute ShadersFlir BosonGitGpu ProgrammingJsbsimMayaNvidia JetsonPhotogrammetryPx4 SitlPythonRos 2Strive_InterfacesStrive_MsgsTensorrtUnreal Engine
19 Days AgoSaved
Remote
Remote San Diego, CA
143K-197K Annually
Senior level
143K-197K Annually
Senior level
Healthtech • HR Tech
Design, develop, and deploy Python- and Java-based scalable REST APIs for a multi-tenant web platform. Collaborate with product, data science, and clinical partners, and ensure software quality, security, and engineering best practices.
Top Skills: JavaMulti-Tenant Web ApplicationsPythonRest ApisSpring
19 Days AgoSaved
Remote
Remote San Diego, CA
95K-135K Annually
Senior level
95K-135K Annually
Senior level
Real Estate • Financial Services • PropTech
Lead AWS-based SRE activities for products migrated from on-prem: ensure reliability, observability, automation, CI/CD (GitOps), Kubernetes/EKS operations, Terraform IAC, database/RDS administration, networking and security, and collaborate with development and platform teams to optimize SaaS operations.
Top Skills: AmiArgocdAWSAws Elastic BeanstalkAws Transfer FamilyAws Well-Architected FrameworkAzure DevopsBashCloudwatchCurlDockerEc2EksFluxcdGitGitopsHTTPIstioKubernetesLinkerdLoad Balancer (Elb/Alb)PowershellPythonRdsService MeshSQLTerraformWget
19 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
Senior level
Senior level
Software
Develop and execute test plans for SiGe ASICs and high-speed mixed-signal devices. Perform RF/mm-wave probing and characterization, troubleshoot electrical/RF/thermal/software issues, compare measurements with simulations, build bench hardware/software for characterization, qualify test stations (Gage R&R, SPC), document test solutions, and coordinate cross-functional test development schedules.
Top Skills: CC++CadenceEm SimulationJmpMatlabNoise Figure AnalyzerOscilloscopePnaPythonSpiceSQLVb.NetVector Network Analyzer (Vna)
19 Days AgoSaved
Remote
Remote San Diego, CA
190K-230K Annually
Senior level
190K-230K Annually
Senior level
Artificial Intelligence • Legal Tech • Software
Lead platforms engineering for scalable cloud infrastructure: design and implement Kubernetes-based systems, optimize data pipelines with AI, refactor stateful services to be stateless, improve autoscaling and reliability, own data ingestion/export, build internal developer tools, enforce security and testing standards, mentor engineers, and participate in on-call rotations.
Top Skills: BashElasticsearchGCPKafkaKubernetesLinuxPostgresPub/SubPythonRubyTerraform
19 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
Mid level
Mid level
Artificial Intelligence • Machine Learning • Productivity • Software
Build and own the GTM tech stack and integrations, create demo environments seeded with realistic data, embed AI agents into sales workflows, stand up revenue data infrastructure (pipeline, forecasting, attribution), and automate customer service flows. Partner closely with Sales, Marketing, Customer Success, and Product Engineering to measure adoption and impact.
Top Skills: ApolloClayCRMCustom GptsFirefliesGongHubspotMakeN8NPythonSalesforceSlackSQLTypescriptZapier
Reposted 19 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
160K-180K Annually
Senior level
160K-180K Annually
Senior level
Healthtech
Lead design and delivery of scalable, cloud-native healthcare systems and real-time data pipelines. Architect event-driven, batch/stream hybrid solutions, integrate clinical data standards, optimize performance and costs, mentor engineers, and collaborate with product and stakeholders to deploy resilient, compliant services.
Top Skills: Amazon KinesisAmazon RedshiftApache AirflowApache FlinkApache KafkaAWSCcdaDatadogDicomDynamoDBFastapiFhirFlaskGoogle BigqueryHl7 V2Hl7 V3JavaKafka StreamsKibanaKubernetesNoSQLPythonSnowflakeSpark StreamingSpring BootSQL
19 Days AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Artificial Intelligence • Big Data • Machine Learning
Design and lead large-scale AWS migrations (rehost/replatform), architect cloud infrastructure and platforms, automate migrations with IaC and scripting, troubleshoot OS/database issues, and implement hybrid networking and security best practices.
Top Skills: Alb)AnsibleArtifactoryAuto Scaling (Asg)Aws (VpcAws CloudformationAws EcrAws MgnAws Migration EvaluatorAws SsmBash/ShellBoto3CdkChefCloudendureCloudtrailCloudwatchControl TowerCore JavaDirect ConnectDmsDockerDouble-TakeEc2EksEsxGitIamJenkinsKmsKubernetesLambdaLanding ZoneMigration HubMongoDBNsxPostgresPuppetPythonRdsRedisS3ScalaSmsSnsSonarqubeSqsTerraformVcenterVm Export/Import)VmotionVmware (Vsphere
19 Days AgoSaved
Remote
Remote San Diego, CA
120K-160K Annually
Senior level
120K-160K Annually
Senior level
Information Technology • Software • Cybersecurity
Design, build, and maintain scalable web applications, APIs, and backend services across multiple stacks. Make architectural decisions, remediate technical debt, lead client communication and demos, participate in agile teams and code reviews, uphold testing and debugging practices, and contribute to internal best practices and thought leadership.
Top Skills: AWSAzureC#/.NetDatadogDjangoDockerGitGoGrafanaGraphQLGrpcJavaJestKafkaKubernetesMinitestNode.jsOpentelemetryPostgresPythonReactRestRspecRtlRuby On RailsRustSentryTerraform
19 Days AgoSaved
Remote
Remote San Diego, CA
80K-130K Annually
Mid level
80K-130K Annually
Mid level
Artificial Intelligence • Information Technology • Software
First dedicated QA hire responsible for test planning, building and maintaining automated test suites across a TypeScript+Python stack, integrating tests into CI/CD, running regression and performance tests, identifying and verifying bugs, improving observability, and documenting QA processes.
Top Skills: CypressDockerFastapiGitGithub ActionsGraphQLJestK6PlaywrightPostgresPostmanPytestPythonRedisRenderRestTemporalTypescriptUnittest
19 Days AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Artificial Intelligence • Cloud • Information Technology • Software
Design and build scalable, secure cloud-native backend systems in AWS. Implement event-driven architectures, async concurrent processing, data pipelines, serverless services, and REST APIs (Flask/FastAPI). Ensure performance, caching, testing, debugging, and cloud security (IAM, encryption, authentication).
Top Skills: Asynchronous ProgrammingAWSCachingEmbedding-Based SearchEncryptionFastapiFlaskGenaiIamJwtLlm ApisMessage QueuesNetwork IsolationOauthPub/SubPythonRagRestful ApisServerlessVector Databases
19 Days AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Software
Lead design and hands-on delivery of cloud-first solutions on Microsoft Azure and related platforms. Translate stakeholder requirements into architecture patterns, document designs, mentor teams, build POCs, migrate legacy apps, and apply AI responsibly to improve delivery and quality.
Top Skills: Agentic FrameworksAksAzure Container AppsAzure Data FactoryAzure DatabricksAzure SynapseDocumentdbGithub ActionsGithub Advanced SecurityGithub EnterpriseIstioM365AzureMicrosoft FabricMicrosoft FoundryPower BIPowershellPythonRagRhelSQL ServerTerraformUbuntuWindows
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