Top Remote Python Jobs in San Diego, CA

Lead reliability, observability, and resilience for cloud-based financial SaaS. Define SLOs/SLIs, design monitoring/tracing, own incident response and runbooks, build IaC and automation, implement AIOps, perform chaos and load testing, and write production-grade Python tooling while ensuring security and compliance.

Lead administration and support of corporate Microsoft infrastructure, VDI/RDS access platforms, virtualization, storage, backups, and cloud services. Perform AD domain/forest migrations, replace legacy VDI and load‑balancing stacks, maintain documentation, resolve incidents to SLA, participate in projects and on‑call rotation, and collaborate with NOC, InfoSec, DevOps, and L2 teams.

Design, implement, and operate low-latency, high-throughput C++, Go, and Python services for real-time sensor ingestion, tracking, inference, and data pipelines. Build IPC/messaging interfaces, optimize data structures and Protobuf serialization, deploy containerized services on Kubernetes (Argo/Helm) in GCP, and implement observability, testing with historic/simulated data, and end-to-end O&M.

Design, build, and maintain no-code/low-code and custom-code automations for influencer programs: discovery, onboarding, contracts, content tracking, reporting, and payments. Own integrations, webhooks, error handling, secrets management, and data validation (SQL) while partnering with marketing, finance, legal, and BI.

Design, build, and lead AWS-based contact center solutions (Amazon Connect, Salesforce Service Cloud Voice). Develop integrations, implement CloudFormation/Lambda, apply IaC and CI/CD, perform code reviews, provide technical advisory, documentation and training, and ensure secure, scalable architectures.

Design and build React-based applications, support component design and deployment practices, implement data storage and scalable performance optimizations, work with clients and technical leads, apply UI/UX principles, testing at all levels, collaborate on code reviews and agile delivery.

Embed with U.S. government and military customers to deploy, integrate, debug, and maintain C2 software in austere operational environments. Build integrations, troubleshoot distributed systems, contribute to core services, support on-call and nonstandard hours, and travel extensively to ensure mission reliability and deliver field-driven product improvements.

Build end-to-end production features across backend, frontend, and database. Integrate LLM APIs and agentic workflows into products and internal developer tools. Improve CI/CD, deployment, and developer infrastructure. Debug production issues on GCP and containerized services; participate in code reviews and architecture discussions on a small collaborative team.

Embed with customers to discover needs, design and implement production-grade integrations (APIs, data pipelines, event-driven workflows), deploy and troubleshoot solutions, train IT teams, and drive adoption and measurable business outcomes.

Configure and implement Alkami digital banking products and third-party integrations, troubleshoot technical issues, perform testing and validation, document configurations, coordinate with project managers and vendors, and support clients through implementation and post-go-live stabilization.

Design and develop core backend systems and APIs for AI applications, ensuring performance and reliability while collaborating with frontend teams.

Designs and develops silicon photonics integrated circuits, managing the entire development process, including testing and analysis for cutting-edge photonic devices and systems-on-chip.

As a Senior Fullstack Engineer, you'll architect and build a high-concurrency auction engine, leveraging AI for enhanced user experiences and system reliability.

As a Senior Fullstack Engineer, you'll build financial systems, design lending infrastructure, implement payment integrations, and create user interfaces, ensuring correctness and reliability.

Design, build, and operate scalable backend services and APIs for a SaaS platform using Python/FastAPI. Ensure reliability, performance, and observability across distributed systems. Work with PostgreSQL, SQLAlchemy, Temporal, Redis, AWS, and Terraform. Build frontend features with React and TypeScript, integrate third-party APIs, adopt AI-assisted development tools, mentor engineers, and drive architecture and developer experience improvements.

As a Database Reliability Engineer at ClickHouse, you'll improve reliability, manage escalation processes, support incident response, and enhance database performance while collaborating across teams.

Design and build operational data systems, including pipelines, storage layers, and APIs for near real-time enforcement and insights, balancing streaming and batch paradigms.

The role involves building and debugging components across the stack, focusing on patient care coordination tools, while collaborating with AI technology.

Design, implement, and operate hybrid-cloud infrastructure and platform services. Automate infrastructure (IaC), manage Kubernetes (EKS and on-prem), provision distributed systems (Spark, Kafka, databases), build CI/CD pipelines, improve cloud governance/security, and collaborate with trading, development, and operations teams to maintain reliable production systems.

The Senior Forward Deployed Engineer will deploy and validate AQNav systems, drive success during tests, communicate with stakeholders, and bridge operations with research and engineering.

The Senior Backend Engineer will lead client projects, build AI solutions, and develop technical standards while mentoring junior engineers.

Lead design and delivery of customer-facing data product applications, building full-stack experiences (frontend, backend, APIs) using TypeScript, React, Node.js, and Python. Partner with Product and data teams to convert analytics and prototypes into production-grade workflows, establish software engineering best practices, mentor engineers, and prioritize customer value through testing, observability, and operational ownership.

The Senior Full Stack Engineer builds and ships features across frontend and backend systems, working with various frameworks and databases, while collaborating on technical specifications and improving developer experiences.

The Senior Software Engineer will develop orchestration and autoscaling for the Lucenia search platform, working with cloud technologies and Kubernetes to manage services and mentor team members.

Manage a team developing accelerated image and data compression libraries. Define project goals, roadmap, and scope; ensure execution and delivery; elevate engineering practices; collaborate with internal and external customers and the open-source community while fostering an inclusive, innovative environment.