Top Remote Python Jobs in San Diego, CA

Design, develop, and maintain production-scale APIs and distributed systems in Golang on Kubernetes. Provide technical leadership, participate in design reviews, write tests and documentation, collaborate cross-functionally, improve developer workflows including AI-assisted tooling, and support on-call operations.

You will design and implement scalable backend systems integrating August infrastructure with third-party DeFi protocols while collaborating with engineering teams.

The Principal GNC Engineer will drive spacecraft GNC architecture, perform verification and validation, develop tools and algorithms, and support launch operations, while mentoring engineers.

As a Staff Software Engineer at Saris AI, you will lead the design and architecture of core systems, build AI-powered software for financial workflows, and drive engineering excellence while collaborating with product and leadership teams.

The Full Stack Engineer will architect, implement, and maintain user-facing applications, improve UX, and design internal tools while collaborating with a team in a startup environment.

Lead statistical programming for multiple clinical development projects, ensuring quality and compliance while collaborating with cross-functional teams and overseeing data analysis.

Build and maintain pipelines and web scrapers to create a large case-law dataset, implement metadata extraction (citations, overruling/appeals), ensure scraper reliability, optimize core utilities, expose data via APIs/websockets, and benchmark/evaluate tasks.

The Senior Cloud Database Engineer at Marqeta will automate AWS Aurora, improve database performance, and ensure high availability across multiple regions. Responsibilities include contributing to technical vision, disaster recovery solutions, and mentoring junior engineers.

The Full Stack Engineer will develop and maintain scalable web applications, design system architecture, optimize performance, and collaborate with teams for code reviews in a hybrid work environment.

As a Senior Backend Engineer at Akkio, you'll design and build backend systems for an AI-driven platform, lead projects, mentor junior engineers, and optimize cloud infrastructure.

The role involves designing and implementing SaaS solutions, leading development teams, ensuring high software engineering standards, and maintaining system performance.

The Senior Backend Data Engineer will extend data ingestion and processing pipelines, build APIs and backend services, and provide technical leadership.

The GTM Systems Engineer will manage the commercial technology stack, focusing on CRM administration, data integrity, tooling automation, and cross-functional collaboration to enhance sales and marketing operations.

As an iOS Engineer, you'll design and implement the mobile app's upload flows, optimize performance, and collaborate with backend and ML teams on features.

The Data Engineer will build and manage scalable data pipelines and databases, collaborate on architecture, and drive data systems towards real-time capabilities in a fast-paced, innovative environment.

Design, scale, and operate secure AWS cloud infrastructure (EKS, IAM, RBAC); build and maintain IaC (Terraform/Terragrunt), GitHub Actions CI/CD, Datadog observability, and Python automation; document runbooks, participate in on-call rotations, postmortems, and Agile workflows to improve reliability and security.

Lead full-flow physical implementation for LPU ASICs: synthesis, floorplanning, place & route, timing closure, UPF/LEC low-power flows, and tapeout. Collaborate with IP, front-end, PnR and sign-off teams to optimize PPA and resolve bottlenecks. Architect automated, data-driven EDA methodologies, implement scripts and AI-assisted optimizations, and ensure sign-off quality including power grid, EMIR, and DFT integration for high-speed SerDes blocks.

As a Senior Database Site Reliability Engineer, you'll design, implement, and maintain PostgreSQL systems, ensure reliability, automate maintenance tasks, and participate in incident response.

Own CI/CD, reliability, and deployment infrastructure for GTM systems (Salesforce, NetSuite, MuleSoft, Workato) and AI agent workloads on GCP and AWS. Build pipelines, observability, environment lifecycle, secrets management, IaC, container security, and runbooks. Partner with developers, Security, and IT to enforce guardrails, perform incident RCAs, and automate tooling to increase deployment safety and velocity.

The Senior Game Build Engineer will improve infrastructure reliability, automate builds, and maintain build systems for various platforms in a large-scale game development project.

Develop and deliver solutions in a DevSecOps environment using cloud-native technologies, focusing on containerized applications, CI/CD pipelines, and data services.

The Verification Engineer will ensure the functionality and quality of digital designs, develop verification environments, and collaborate with RTL design engineers to deliver reliable silicon.

Seeking an experienced DFT Verification Engineer to ensure ASIC DFT logic correctness, building robust verification environments, and collaborating with design engineers on high-quality silicon delivery.

The DevOps Engineer will design and maintain cloud infrastructure for game development, create CI/CD pipelines, promote cloud security, and respond to support issues, enhancing team collaboration and automation.

The role involves validating clocking structures in products, developing test plans, automation, and partnering with design teams to ensure high-quality verification of ASIC designs.