Top Remote Python Jobs in San Diego, CA

Reposted 6 Days AgoSaved
Remote
Remote San Diego, CA
166K-331K Annually
Senior level
166K-331K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead and grow a developer experience team responsible for monorepo strategy, CI/CD, build systems, developer environments, and onboarding. Improve engineering velocity, CI reliability, and developer trust; establish standards, adopt AI-assisted workflows, and partner with infra/ML teams to remove friction for large-scale AI research.
Top Skills: BazelBuild SystemsCC#C++Ci/CdJavaJavaScriptMonorepo ManagementPython
Reposted 6 Days AgoSaved
Remote
Remote San Diego, CA
190K-220K Annually
Senior level
190K-220K Annually
Senior level
Artificial Intelligence • Information Technology • Software • Cybersecurity
The Senior Fullstack Software Engineer will design, implement, and maintain features for Conveyor's SaaS platform, involving both backend and frontend work, while collaborating closely with team members and mentoring juniors.
Top Skills: AWSPostgresPythonReactRestful ApisRuby On Rails
Reposted 6 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
150K-200K Annually
Mid level
150K-200K Annually
Mid level
Artificial Intelligence • Food • Software • Hospitality
Build and ship end-to-end features for a restaurant operating system, lead architecture and technical execution, define product roadmap with cross-functional teams, and maintain high-quality CI/CD and productionized systems.
Top Skills: Aws LambdaAws ServerlessAws Step FunctionsCi/CdDistributed SystemsGoJavaJavaScriptPythonReactTypescript
Reposted 6 Days AgoSaved
Remote
Remote San Diego, CA
190K-220K Annually
Senior level
190K-220K Annually
Senior level
Artificial Intelligence • Information Technology • Software • Cybersecurity
Design, build, and maintain AI-powered B2B SaaS products across frontend, backend, and AI. Own projects end-to-end, collaborate with product and design, ensure maintainability, mentor teammates, and inform roadmap and implementation decisions.
Top Skills: Ai Coding ToolsAWSLlmsPostgresPythonReactRestful ApisRuby On Rails
Reposted 6 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
150K-200K Annually
Mid level
150K-200K Annually
Mid level
Artificial Intelligence • Food • Software • Hospitality
Build and maintain Python backend services and serverless architectures for a restaurant operations platform. Ship end-to-end features, design robust systems, and help define product roadmap. Implement CI/CD and productionization, collaborate with product and GTM teams, and contribute to team culture and technical execution.
Top Skills: Aws LambdaAws ServerlessAws Step FunctionsCi/CdGoJavaJavaScriptPythonReactTypescript
Reposted 6 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
150K-200K Annually
Mid level
150K-200K Annually
Mid level
Artificial Intelligence • Food • Software • Hospitality
Build and ship backend systems and robust architectures for SMB and enterprise restaurant customers. Drive end-to-end development including planning, CI/CD, and productionization. Collaborate on product roadmap, iterate from user feedback, and contribute to team culture and growth.
Top Skills: Ci/CdGoJavaJavaScriptPythonTypescript
Reposted 6 Days AgoSaved
Remote
Remote San Diego, CA
Junior
Junior
Artificial Intelligence • Insurance • Software • Automation
Build and maintain backend services and APIs, write unit tests, debug and optimize systems, support migration from Supabase to cloud, improve reliability, and integrate AI/RPA workflows while learning under senior mentorship.
Top Skills: AIAWSAzureGCPJavaScriptNode.jsPostgresPythonReactRobotic Process Automation (Rpa)Supabase
Reposted 6 Days AgoSaved
Remote or Hybrid
Remote San Diego, CA
120K-200K Annually
Mid level
120K-200K Annually
Mid level
Fintech • Professional Services • Financial Services
Build and scale a fintech platform across accounting, tax, and banking. Own feature lifecycle from design to deployment, write backend and frontend code, improve infrastructure and reliability, and collaborate with product and design to deliver customer-focused features.
Top Skills: AxumCloud RunCloud SqlDjangoGCPNext.JsPostgresPub/SubPythonReactRustSlonikSqlxTerraformTypescript
Reposted 6 Days AgoSaved
Remote
Remote San Diego, CA
Expert/Leader
Expert/Leader
Blockchain • Software • Financial Services • Cryptocurrency
Own backend and AI infrastructure for autonomous trading agents. Build the Go-based agent runtime, execution and data layers, real-time trading systems, deployment platform, model hosting migration, telemetry, CI/CD, monitoring, and incident response. Develop production services primarily in Go, Python, and TypeScript while operating AWS EKS infrastructure. The role requires end-to-end ownership of reliable, low-latency systems managing real-time trading and financially sensitive positions.
Top Skills: Amazon EksAnthropicAWSBigQueryCi/CdClickhouseGoGoogleHyperliquidKubernetesMcpNode.jsOpenclawPostgresPythonRailwayRedisTelegramTensorrt-LlmTgiTimescaledbTypescriptVllmWebsocketsYaml
Reposted 6 Days AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Blockchain • Software • Financial Services • Cryptocurrency
Design and operate secure, scalable, highly available infrastructure for a low-latency decentralized exchange and blockchain network. Own infrastructure automation, CI/CD, Kubernetes performance, observability, security, incident response, disaster recovery, cost optimization, and reliability practices. Mentor engineers, document systems, and participate in on-call rotations while supporting high-throughput trading workloads.
Top Skills: ArgocdAWSBased RollupBashCloudFormationDockerEfkElkEthereumGCPGithub ActionsGitlab CiGoGrafanaHashicorp VaultIamIstioKmsKubernetesLinkerdOpentelemetryPrometheusPulumiPythonRustTerraformWeb3Zero-Knowledge Proofs
6 Days AgoSaved
Remote
Remote San Diego, CA
90K-120K Annually
Mid level
90K-120K Annually
Mid level
Robotics • Biotech • Pharmaceutical • Automation
Provides remote, onsite, and customer-site technical support for laboratory automation platforms. Manages customer cases, troubleshoots software, hardware, networking, robotic, and database issues, deploys and debugs integration code, performs upgrades and configuration changes, trains customers, collaborates with field and internal teams, and documents resolutions and process improvements.
Top Skills: C#Laboratory Automation SoftwarePythonRelational DatabasesRobotic ArmsSerial CommunicationsTcp/Ip
6 Days AgoSaved
Remote
Remote San Diego, CA
90K-120K Annually
Mid level
90K-120K Annually
Mid level
Robotics • Biotech • Pharmaceutical • Automation
Supports laboratory automation customers by managing technical cases, troubleshooting software, hardware, networking, and robotics systems, and deploying integration code. Configures databases, performs upgrades and configuration changes, trains customers, collaborates with field service and software teams, documents issues, and drives resolutions. The role is remote with office and customer-site work and requires approximately 30% domestic travel.
Top Skills: C#Laboratory Automation SoftwarePythonRelational DatabasesRoboticsSerial CommunicationsTcp/Ip
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6 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
138K-219K Annually
Senior level
138K-219K Annually
Senior level
Cloud • Security • Software • Cybersecurity
Design, develop, test, implement, maintain, and support custom web applications and software solutions involving internet security, content delivery, APIs, and cloud computing. Build new applications and platform capabilities, improve existing functionality, contribute to automated unit, functional, integration, and end-to-end testing, and troubleshoot distributed systems and web services.
Top Skills: APIsAutomated TestingCloud ComputingDistributed SystemsJ2EeMicrosoft Sql ServerPerlPythonRestSpringUnix Shell ScriptingWeb Services
6 Days AgoSaved
Remote
Remote San Diego, CA
167K-192K Annually
Entry level
167K-192K Annually
Entry level
Aerospace • Defense • Manufacturing
Develops, integrates, verifies, and validates software for autonomous unmanned aircraft systems. Leads system-level integration and testing across laboratory, ground, flight, HITL, SITL, and simulator environments; analyzes telemetry and test data, troubleshoots anomalies, documents results, and supports corrective actions. Collaborates across software, systems, controls, avionics, and flight-test teams, mentors engineers, coordinates integration activities, and ensures safety, regulatory, and technical compliance.
Top Skills: CC++Data Acquisition SystemsDdsDevOpsHardware-In-The-Loop (Hitl)IntegrityMatlabMavlinkModel-Based DesignPythonRequirements ManagementRosRos2Simulation And ModelingSimulinkSoftware-In-The-Loop (Sitl)Test AutomationVxworks
6 Days AgoSaved
Remote
Remote San Diego, CA
100K-181K Annually
Senior level
100K-181K Annually
Senior level
eCommerce • Software
Build and own rule evaluation engine components for Shippo’s customer-facing data products. Develop high-throughput Python and FastAPI backend services, event-driven integrations, PostgreSQL data models, and React configuration interfaces. Ship features end-to-end with feature flags, testing, observability, and production validation. Collaborate with Data Science, Analytics Engineering, and Product teams, participate in on-call response, contribute to technical design, and help onboard teammates.
Top Skills: ClaudeCursorFastapiKafkaPostgresPythonReact
6 Days AgoSaved
Remote
Remote San Diego, CA
135K-170K Annually
Mid level
135K-170K Annually
Mid level
Artificial Intelligence • Marketing Tech • Mobile • Software
Build and improve distributed data applications powering large-scale audience segmentation and personalized messaging. Own well-scoped features end to end, including design, implementation, testing, deployment, and operation. Collaborate with engineering, product, and design teams while developing expertise in distributed systems, data pipelines, real-time processing, databases, and platform performance.
Top Skills: AlgorithmsData PipelinesDistributed SystemsGoJavaNon-Relational DatabasesObject-Oriented DesignPythonReal-Time ProcessingRelational Databases
Reposted 6 Days AgoSaved
Remote or Hybrid
Remote San Diego, CA
150K-225K Annually
Senior level
150K-225K Annually
Senior level
Artificial Intelligence • Fintech • Machine Learning • Natural Language Processing • Business Intelligence
Lead architecture and implementation of reliability platforms and SRE practices for a production SaaS. Build self-service reliability tooling, drive AIOps automation, advance observability (monitoring, tracing, profiling), lead incident response and postmortems, mentor engineers, and embed production readiness across teams to achieve 99.99% uptime.
Top Skills: AWSAzureContinuous ProfilingDatadogDnsElkGCPGoGrafanaHttp/SKubernetesLoad BalancingOpentelemetryPrometheusPythonTcp/Ip
6 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
140K-219K Annually
Senior level
140K-219K Annually
Senior level
Cloud • Security • Software • Cybersecurity
Develop and deploy automated system tests for distributed systems, improve testing methodologies, validate test plans and cases, and collaborate with developers and QA teams. The role involves software QA, test automation framework development, root cause analysis, functional, stability, integration, and performance testing, plus solving large-scale systems testing challenges using programming and related internet technologies.
Top Skills: C++Ci/CdDistributed SystemsGitJavaScriptMercurialPrestoPythonSQLTest Automation FrameworksTestrail
6 Days AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Information Technology
Designs and leads secure, scalable cloud infrastructure architectures across AWS, Azure, and GCP. Responsibilities include cloud migration and modernization, infrastructure automation, CI/CD, platform engineering, governance, security, compliance, observability, reliability, and cost optimization. The role also advises clients and executives, leads architecture workshops, develops cloud adoption strategies, and mentors engineering teams.
Top Skills: Apptio CloudabilityArm TemplatesAWSAws Cost ExplorerAws EcsAws FargateAzureAzure Cost ManagementAzure DevopsAzure Kubernetes ServiceAzure MonitorBashCi/CdCloud NetworkingCloudFormationCloudhealthCloudwatchContainersEncryptionFinopsGCPGcp Operations SuiteGithub ActionsGoogle Cloud RunIamInfrastructure As CodeJenkinsKey ManagementKubernetesPythonService MeshesSreTerraformVirtualization
6 Days AgoSaved
Remote
Remote San Diego, CA
Mid level
Mid level
Healthtech
Manage AWS cloud infrastructure, CI/CD pipelines, Terraform-based infrastructure, containers, monitoring, and operational automation. Administer Microsoft 365, Entra ID, Intune, Windows, and macOS devices. Support onboarding, offboarding, remote technical issues, identity and access management, IT assets, documentation, security standards, and incident troubleshooting while collaborating with engineering, security, operations, and vendors.
Top Skills: Apple Business ManagerAWSBashCi/CdCloudwatchConditional AccessDockerEc2Exchange OnlineFilevaultGitIamJamf ProKandjiKubernetesLinuxMfaMicrosoft 365Microsoft Defender For EndpointMicrosoft Entra IdMicrosoft IntuneMosyleOnedrivePythonRoute 53S3SharepointTeamsTerraformTerragruntVpcVpnWindows Autopilot
6 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
95K-115K Annually
Expert/Leader
95K-115K Annually
Expert/Leader
Healthtech • Financial Services
Designs, implements, secures, and supports hybrid enterprise networks across Azure, AWS, on-premises data centers, offices, and remote locations. Responsibilities include cloud connectivity, routing, switching, firewalls, VPNs, monitoring, troubleshooting, Zero Trust controls, high availability, disaster recovery, and Infrastructure as Code automation. The engineer leads migration and modernization initiatives, coordinates with vendors, supports office deployments, documents network environments, participates in on-call support, and mentors junior staff.
Top Skills: Amazon Route 53Amazon Web Services (Aws)AnsibleArm TemplatesAws CloudformationAws Direct ConnectAws Transit GatewayAws VpcAws VpnAzure Application GatewayAzure BicepAzure DnsAzure ExpressrouteAzure FirewallAzure Private LinkAzure Virtual NetworksCisco CatalystCisco MerakiCisco NexusCisco Secure FirewallDnsElastic Load BalancingFortinetInfrastructure As CodeLanAzurePalo AltoPowershellPythonRest ApisSd-WanTerraformVpnWanWlanZero Trust
6 Days AgoSaved
Remote
Remote San Diego, CA
230K-250K Annually
Senior level
230K-250K Annually
Senior level
Artificial Intelligence • Insurance • Software • Automation
Leads and develops software engineers through mentorship, feedback, hiring, and career growth. Partners with product and design to deliver secure, scalable, reliable features; guides architecture and engineering best practices; improves processes, velocity, and execution; and translates customer and business needs into technical roadmaps. The role requires hands-on leadership in a high-growth startup environment and ownership of engineering culture, performance, reliability, and talent development.
Top Skills: AWSDockerGraphQLNode.jsPostgresPythonReactTypescript
6 Days AgoSaved
Remote
Remote San Diego, CA
Junior
Junior
Information Technology • Consulting
Develop data integration, health information exchange, and IRIS application solutions for healthcare and other clients. Responsibilities include designing robust distributed applications, defining project specifications, selecting implementation strategies, collaborating directly with clients, and contributing to large-scale InterSystems IRIS and HealthShare implementations. Strong communication and software development skills are essential, with healthcare IT and healthcare data integration expertise highly valued.
Top Skills: .NetCC#C++C-CdaCaché ObjectscriptCcdFhirHl7Intersystems HealthconnectIntersystems HealthshareIntersystems IrisJavaJavaScriptMumpsPythonSQLTrakcareX12
6 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
140K-219K Annually
Senior level
140K-219K Annually
Senior level
Cloud • Security • Software • Cybersecurity
Develop and lead automated testing for software features and major releases on Agile teams. Design object-oriented automation frameworks, automate tests using Python or similar languages, perform white-box, black-box, functional, and performance testing, investigate defects, manage test lab environments, estimate testing efforts, mentor engineers, and report testing status.
Top Skills: CC++JavaLinuxPython
Reposted 6 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
120K-261K Annually
Senior level
120K-261K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Design, build, test, and operate production-grade, secure, and scalable software and services. Partner with customers to translate requirements into technical designs, drive engineering best practices (CI/CD, testing, observability), deliver end-to-end solutions, lead technical workstreams, and apply AI/LLM approaches where appropriate to produce production-ready outcomes.
Top Skills: AIAutomated TestingCC#C++Ci/CdCloud Ai PlatformsJavaJavaScriptLlmObservabilityPrompt EngineeringPythonRetrieval-Augmented Approaches
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