Top Remote C# Jobs in San Diego, CA

Develop, design, integrate, test, and maintain software for radiation therapy medical devices. Build treatment-planning systems, implement automated tests, troubleshoot issues, contribute to architecture and requirements, and support high-performance computational solutions. Collaborate across software, systems, testing, product, and clinical teams while following rigorous quality and regulatory processes. Some travel under 10% may be required.

Lead the design and development of scalable .NET services and APIs for a real-time trading platform. Own systems through production, contribute to architecture and observability, support incident response, mentor engineers, and drive cross-team technical initiatives. Collaborate with product and design while occasionally contributing to React and TypeScript frontend development. Build reliable, high-throughput distributed systems and improve engineering standards, tooling, testing, and operational excellence.

Design, develop, and maintain scalable billing and invoicing systems using C# and PHP. Lead architecture, code reviews, mentoring, CI/CD improvements, monitoring, database optimization, security, and PCI DSS compliance. Use Claude and Cursor in daily development while validating generated code for correctness, security, performance, and maintainability. Collaborate across Product, Engineering, QA, and support teams to deliver reliable payment-processing services and resolve complex technical issues.

Designs and governs Dynamics 365 Sales, Field Service, and Business Central solutions, Dataverse data models, integrations, security, and deployment pipelines. Builds and reviews C# plugins, JavaScript, Power Automate flows, and integration code; improves synchronization reliability and monitoring. Partners with business leaders, supports acquisitions and migrations, maintains architecture governance, and provides senior technical guidance without direct reports.

Build and maintain full-stack capabilities for Octane’s loan servicing ecosystem using Python, Django, PostgreSQL, and React. Design scalable APIs, data-integrity safeguards, and user interfaces; write automated tests; troubleshoot complex bugs; optimize performance; participate in code reviews; collaborate cross-functionally; and mentor junior engineers while using AI-assisted development tools.

Leads and develops a globally distributed engineering team while shaping technical strategy, modernizing a SaaS platform, and building scalable solutions with .NET, React, APIs, and cloud technologies. Responsibilities include mentoring engineers, influencing architecture, improving CI/CD, reliability, delivery practices, and advancing responsible AI adoption across engineering.

Leads and develops a globally distributed software engineering team while remaining 50% hands-on. Responsibilities include driving technical strategy and modernization, building scalable SaaS solutions with .NET, React, APIs, and cloud technologies, improving CI/CD and reliability, mentoring engineers, influencing architecture, and advancing responsible AI use across engineering.

Develop and improve Azure Kubernetes Service capabilities across Linux and Windows, building reliable container orchestration and cloud infrastructure at global scale. Responsibilities include advancing Kubernetes components, improving service quality, accelerating engineering velocity, automating incident prevention and remediation, and integrating AI tools into development workflows. The role focuses on distributed systems, containers, Kubernetes, DevOps tooling, and AI/ML workload infrastructure.

Design, build, test, deploy, and operate secure, reliable, scalable software and production services. Partner with customers and stakeholders to translate business needs into technical solutions, lead technical workstreams, and deliver outcomes end-to-end. Apply engineering best practices including code review, automated testing, CI/CD, observability, and documentation. Preferred work includes deploying AI or LLM solutions using cloud AI platforms, model evaluation, monitoring, and data-quality practices.

Develops, tests, deploys, maintains, and improves .NET web applications for a federal government client. Translates user stories into software, designs application components and data models, develops vendor interfaces, performs code reviews, monitors system metrics, and creates technical and user documentation. The role participates in Agile processes, supports reporting requests, maintains existing systems, and contributes to software delivery and continuous improvement. Candidates need at least two years of .NET development experience and must be able to obtain Public Trust clearance.

Develops, tests, documents, maintains, and enhances software solutions using Appian and related technologies. Integrates Appian with external systems and services, resolves technical problems, remediates security vulnerabilities, improves performance, and participates in planning and user-story analysis. The role follows software development processes, documents standards, and mentors engineers while helping prioritize work for a development team.

Develops, configures, tests, documents, deploys, and supports business applications for clinical trial operations. The role involves C# and ASP.NET MVC development, database object design, defect resolution, site support, source control, change management, and collaboration with project and solution teams. Work must follow software development standards, SLAs, SOPs, Good Clinical Practice, 21 CFR Part 11, and other regulatory requirements.

Develop and deliver full-stack features using .NET Core, C#, React or Angular, REST APIs, and MySQL. Write unit and integration tests, troubleshoot issues, optimize performance, and improve system reliability. Collaborate with technical and product teams, participate in code reviews, and independently own features from implementation through delivery. The role requires strong communication in English and supports remote work from Latin America.

Design and evolve the architecture of DraftKings’ regulated prediction-markets exchange. Own the technical roadmap, distributed-system foundations, scalability, reliability, performance, operational health, and resilience testing. Collaborate with product, infrastructure, platform, brokers, market makers, and clearing partners. Contribute hands-on to critical systems, guide design standards, mentor engineers, and implement AI tooling and guardrails for engineering workflows.

Provides technical leadership for architecture and evolution of large-scale distributed data platforms supporting Azure network telemetry. Designs streaming and batch systems, establishes reusable engineering patterns, drives cross-team technical strategy, and owns capabilities from design through production operations. Ensures scalability, reliability, security, performance, data quality, and operational excellence while mentoring engineers and influencing technical leaders. The role also involves architectural reviews, dependency management, risk reduction, and applying AI or machine learning approaches to operational systems.

Designs and develops software to automate onboarding, validation, management, tracking, and lifecycle operations for new hardware deployed in Microsoft datacenters. Responsibilities include requirements analysis, system design, coding, debugging, optimization, reliability engineering, monitoring, on-call support, and incident response. The role collaborates with Azure teams and stakeholders while improving scalability, security, availability, observability, and performance across cloud and distributed systems.

Leads architecture and production delivery of a near-real-time observability platform for large-scale AI supercomputers. Responsibilities include telemetry ingestion, processing, storage, querying, topology and health modeling, 1P/3P data convergence, AI-assisted anomaly detection, technician dashboards, repair validation, security, reliability, cross-team technical leadership, and mentoring.

Design and build healthcare messaging solutions using C# .NET, RESTful APIs, Azure, and DaVinci FHIR. Develop web services, map healthcare message structures, write unit and integration tests, review code, troubleshoot production issues, and deploy software to Azure. Collaborate across teams, mentor junior engineers, manage complex projects, and improve prior authorization workflows.

Leads full-cycle technical implementations of a cloud-native digital banking platform, including requirements discovery, configuration, custom development, integrations, testing, data migration, environment management, deployment, and production support. Serves as the primary technical client contact, translates business needs into solutions, troubleshoots technical issues, coordinates cross-functional delivery, and improves implementation processes, documentation, tooling, and reusable components.

Designs, deploys, documents, monitors, and diagnoses cloud-based distributed services and client applications. Provides escalation support, supports AI-enabled software development, manages scaling and databases, maintains CI/CD environments, tests APIs, and monitors application releases and dependencies. The role collaborates across development and operations teams in a fast-moving product company.

Designs, develops, and supports scalable backend services, REST and gRPC APIs, automated testing, monitoring, and continuous delivery. Leads system architecture and technical initiatives, performs code reviews, mentors engineers, troubleshoots production issues, and documents designs and operational procedures. The role also supports major customer implementations and integrations on the IBM iSeries platform while collaborating with product, engineering, and customer stakeholders.

Develop and maintain full-stack healthcare applications using C#, .NET, ASP.NET Core, JavaScript, and SQL Server. Design APIs, services, background jobs, database procedures, and responsive interfaces; troubleshoot across application and deployment layers; write automated tests; modernize legacy systems; build secure healthcare integrations; and protect sensitive data. Collaborate with product, QA, support, and implementation teams while participating in design reviews, code reviews, testing, and release validation.

Design and lead development of high-performance networking infrastructure for large-scale AI training and inference in Azure. Architect low-latency, low-jitter communication frameworks, optimize distributed systems, benchmark scalability, resolve complex networking issues, and improve reliability, observability, and performance. Mentor engineers, create technical designs, manage dependencies, and participate in on-call operations for critical services.

Supports the design, development, testing, maintenance, and troubleshooting of web applications using C#, ASP.NET, JavaScript, HTML, ExtJS, and SQL Server. Responsibilities include writing code and database queries, debugging application and performance issues, providing Tier-3 support, participating in Agile/Scrum ceremonies and code reviews, and documenting software modules and fixes.

Build and evolve scalable backend systems and APIs for a large SaaS platform. Partner with Product, Design, and QA from ideation through deployment, contribute to microservices architecture, improve testing and observability, identify operational risks, and mentor teammates. The role emphasizes reliable, maintainable solutions, strong collaboration, architectural decision-making, and continuous improvement.