Top Remote C# Jobs in San Diego, CA

Develop and maintain software applications supporting genetic testing and clinical reporting workflows. Collaborate with geneticists, bioinformaticians, laboratory professionals, and business stakeholders to define requirements and architecture. Troubleshoot defects, ensure data accuracy and system reliability, document processes, support continuous improvement, and comply with security, regulatory, and organizational requirements.

Designs, develops, tests, and deploys Microsoft Power Platform and Dataverse solutions for clients. Builds Power Automate flows, C# plugins, JavaScript customizations, Power Apps, integrations, and data migrations. Defines requirements, manages project scope and deliverables, delegates work to offshore developers, and maintains customer relationships while delivering projects on time and within budget.

Own and evolve Swyfft’s partner-facing insurance API, including resource design, versioning, backward compatibility, authentication, rate limiting, error handling, metrics, documentation, and contract testing. Build production C# code, maintain the translation layer between public APIs and internal systems, support partner integrations, and collaborate with QA and product. The role requires substantial public API experience, strong API security and multi-tenancy knowledge, and fluency in C#, ASP.NET Core, SQL Server, and Azure.

Design, build, and implement Dynamics 365 solutions in a cloud/microservice environment. Develop C#/.NET plugins, APIs, and Azure Functions; participate in requirements analysis, code reviews, testing, deployment, and SDLC documentation. Collaborate with Agile teams, interface with clients, mentor junior developers, and support VA federal projects.

Design, build, test, and operate production-grade, secure, and scalable software and services. Partner with customers to translate requirements into technical designs, drive engineering best practices (CI/CD, testing, observability), deliver end-to-end solutions, lead technical workstreams, and apply AI/LLM approaches where appropriate to produce production-ready outcomes.

Designs, develops, maintains, and troubleshoots scalable software applications using .NET, SQL Server, UI frameworks, and cloud technologies. Collaborates with product owners, developers, testers, and technology leads; participates in code reviews; writes documented code; and improves software development practices.

Lead performance engineering for massive-scale HPC and AI workloads across InfiniBand-connected GPU clusters. Diagnose communication bottlenecks, analyze fabric behavior, tune RDMA and QoS, develop telemetry tooling, optimize topology-aware communication, benchmark distributed workloads, and collaborate with operations and hardware vendors on next-generation interconnects.

Lead the design and development of Azure Compute Fleet capabilities that orchestrate Virtual Machine Scale Sets across regions. Build distributed control-plane services, APIs, and workflows for capacity placement, scaling, failover, and lifecycle management. Collaborate across Azure engineering teams, drive AI-enabled engineering improvements, participate in on-call operations, and improve reliability, observability, performance, and recovery for hyperscale cloud services.

Design, build, operate, and support backend services powering an enterprise AI platform. Responsibilities include developing APIs, gateways, orchestration, tenancy, entitlements, metering, integrations, governed data access, and distributed platform capabilities. The engineer owns services across design, implementation, testing, deployment, monitoring, reliability, and support while addressing failure modes, consistency, idempotency, and scalability.

Build and improve Azure Kubernetes Service capabilities for Linux and Windows containers. Develop distributed cloud infrastructure, automation, observability tooling, and reliability improvements at global scale. Support AI-native infrastructure, including GPU orchestration, model deployment, inference, and platform operations. Accelerate engineering workflows, prevent production incidents, integrate AI tools, and contribute to Kubernetes and cloud-native platform innovation.

Develop and support full-stack software using C#, .NET Core, ReactJS, MVC, LINQ, REST APIs, and SQL Server. Responsibilities include designing, testing, deploying, troubleshooting, and upgrading applications; maintaining data feeds and interfaces; participating in software reviews; supporting continuous improvement; and collaborating with internal and external customers. The role is remote within the United States, requires US citizenship, may require security clearance eligibility, and may involve 5% travel.

Develop, test, maintain, and support enterprise applications and services using C#, .NET, ASP.NET Core, Web API, Entity Framework Core, and SQL Server. Responsibilities include API and database integration, code reviews, automated testing, debugging, performance improvements, release readiness, production troubleshooting, and collaboration with product, architecture, QA, and operations teams.

Design, develop, deploy, and support enterprise integrations for tolling systems using C#, .NET, Azure, SAP, CRM, IVR, APIs, middleware, and external platforms. Build secure REST APIs, microservices, Azure Functions, and Service Bus solutions; optimize high-volume data flows and IVR experiences; integrate payment, traffic management, and backend systems; document technical solutions, testing, impacts, and standards compliance.

Design, develop, deploy, and operate cloud-scale Azure regional networking infrastructure spanning router hardware, operating systems, optical transceivers, and distributed orchestration systems. Lead architecture and cross-team technical initiatives, write maintainable code, improve reliability, observability, performance, and automation, apply AI-driven engineering practices, and mentor engineers while collaborating with hardware, supply chain, datacenter operations, research, vendors, and senior leaders.

Provides technical leadership for enterprise-scale software supporting healthcare revenue cycle operations. Designs scalable applications, APIs, microservices, integrations, cloud-native solutions, and healthcare interoperability workflows using HL7, FHIR, and EDI/X12. Leads architecture, automation, security, performance, code reviews, troubleshooting, modernization, and technical strategy while collaborating with product, operations, analytics, infrastructure, and engineering teams.

Build and support complex features across C#/.NET back-end services and React front ends. Responsibilities include technical design, API and data modeling, secure and tested coding, production troubleshooting, code reviews, mentoring, documentation, and improving engineering practices. Collaborate with Product, QA, DevOps, Technical Leads, and architecture teams while balancing delivery, maintainability, performance, accessibility, observability, and security.

Own the architecture, implementation, and operational excellence of major Azure Boost DPU software components. Develop low-level systems software spanning operating systems, virtualization, networking, storage, device management, and hardware interfaces. Lead complex cross-functional initiatives, optimize hyperscale performance and reliability, resolve system-level issues, establish engineering practices, influence platform architecture, and mentor engineers across Azure infrastructure teams.

Lead development of AI infrastructure for large-scale GPU training and inference. Design workload scheduling, serving, orchestration, resource governance, failover, and multitenant Kubernetes platforms. Build reliable C# and Go services, optimize GPU fleet performance, and drive observability, diagnostics, and production operations. Provide technical leadership, architectural direction, mentoring, and cross-team collaboration across cloud infrastructure, hardware, networking, and AI deployment teams.

Designs, develops, and supports full-stack enterprise applications using cloud and web technologies. Provides technical leadership in architecture, solution design, documentation, application lifecycle management, and production troubleshooting. Collaborates with stakeholders, mentors developers, establishes development standards, and delivers scalable solutions integrating ERP and other business systems.

Designs, builds, scales, and operates distributed CI/CD services supporting millions of builds, tests, and releases. Develops code for Azure-based infrastructure spanning virtual machines, containers, and custom lab environments. Responsibilities include requirements analysis, architecture and design documentation, estimation, debugging, optimization, operational playbooks, on-call incident response, monitoring, reliability improvements, and mentoring engineers.

Lead the rearchitecture and development of a cloud-native Banking as a Service platform. Design scalable APIs, microservices, event-driven systems, and partner integrations using modern cloud, DevOps, observability, and security practices. Drive architectural strategy, technical debt reduction, incident response, code quality, compliance, and continuous delivery. Mentor engineers, collaborate with product and architecture teams, evaluate emerging technologies, and own capabilities through project delivery.

Leads complex software initiatives from architecture through delivery while remaining hands-on. Designs scalable cloud-native systems, mentors engineers, drives code quality, testing, CI/CD, observability, technical debt reduction, and production reliability. Partners with Product, QA, Security, Infrastructure, and leadership to align technical execution with business objectives. Requires deep Microsoft-stack, Azure, distributed systems, database, and automated testing expertise.

Manage and improve cloud-based database infrastructure supporting a mission-critical SaaS platform. Responsibilities include database observability, performance tuning, troubleshooting, migrations, schema improvements, high availability, disaster recovery, incident response, and root-cause analysis across SQL Server and PostgreSQL. The role also automates operational processes, standardizes configurations and deployments, supports Engineering and SRE teams, and manages database tickets and maintenance activities.

Performs manual functional, regression, exploratory, and smoke testing for C#, Visual Studio, and .NET applications. Develops test plans, test cases, and acceptance criteria; identifies coverage gaps; documents defects and risks; and participates in Agile sprint planning, refinement, and defect triage. Collaborates with cross-functional teams to support quality releases and is expected to develop proficiency in software testing, debugging, version control, CI/CD, and relevant testing tools.

Build secure, reliable cloud and AI software solutions from prototype through production. Partner directly with customers and multidisciplinary teams to translate business goals into technical requirements, architect scalable services, and deliver measurable outcomes. Provide technical leadership, mentor engineers, establish reusable frameworks, apply responsible engineering practices, and support deployment, observability, adoption, and knowledge transfer. The role may involve designing and operating AI or LLM-based systems and traveling up to 25%.