Top Senior Machine Learning Jobs in Kansas City, MO

Design, fine-tune, evaluate, and deploy LLM-driven, user-facing browser features using RAG, embeddings, prompt engineering, and modern ML tooling. Lead end-to-end model lifecycle, run production experiments, collaborate with product and engineering, and document and review work with an emphasis on privacy, latency, and usability.

Lead MLOps for production ML lifecycle: deploy and serve models, build scalable reproducible pipelines for large protein-design workloads, implement CI/CD and observability, optimize GPU/accelerated compute, and enable self-service tooling for researchers.

Consult as a fractional data scientist for hedge funds, private equity firms, and family offices. Lead data science initiatives: build infrastructure, develop and deploy models, create portfolio dashboards, monitor post-deployment performance, and partner with investment teams to turn data into actionable investment insights. Advise on vendor selection, data quality, technology stacks, KPIs, and governance.

Lead client-facing architecture and delivery of production-grade GenAI systems. Design scalable LLM, agentic, RAG, recommender, and LTR solutions, manage client engagements, mentor ML engineering teams, and oversee project lifecycle from discovery to deployment and monitoring.

Build and productionize ML models and data infrastructure to analyze millions of chaos engineering experiments, detect and explain failures, recommend automated remediation, and integrate AI-driven failure analysis into Gremlin's product using techniques like causal inference, graph ML, time-series modeling, and reinforcement learning.

Lead architecture and technical strategy for Lyra's ML and generative AI platform. Design training, fine-tuning, and low-latency inference infrastructure (RAG, vector DBs), set ML/AI SDLC standards (dataset lineage, CI/CD, evaluation, monitoring), partner with cross-functional clinical and product teams, mentor senior engineers, deliver prototypes and critical code, and ensure secure, reliable production ML systems.

The Senior Manager, Data Science/ML will lead a team to enhance product innovation through data science, focusing on ML and experimentation frameworks that boost customer engagement. Responsibilities include defining product strategy, building ML models, and collaborating with cross-functional teams to shape product roadmaps.

The Senior ML Engineer will automate component placement on PCBs, working on R&D and production using ML and optimization techniques.

As a Senior/Staff ML Systems Engineer at Quilter, you'll design and maintain ML infrastructure for automated PCB component placement, manage data pipelines, and lead systems design reviews while ensuring project efficiency and reliability within a fully distributed team.

The role involves owning and delivering AI-powered features for Calendly, collaborating with multiple teams, and applying machine learning solutions for product enhancement.

Build and operate high-throughput experimentation and recommendation infrastructure. Design APIs and services, use agentic AI workflows (LLMs) for development, ensure performance and reliability, participate in on-call, mentor teammates, and codify AI-native engineering practices.

The role involves managing the ML lifecycle, developing scalable ML systems, and collaborating on AI-first product solutions focusing on Large Quantitative Models.

As a Senior Machine Learning Engineer, develop LLM evaluation frameworks and agentic AI workflows to extract insights from conversations and optimize customer experiences.

Build and expand in-database ML model catalog: implement new model types, ensure framework parity with scikit-learn/Spark ML, optimize training and inference at petabyte scale, extend SQL-level linear algebra, and collaborate across teams to deliver correct, performant ML features and documentation.

Design, build, and productionize ML systems focused on information extraction, retrieval, ranking, and recommendation. Own full ML lifecycle from feature engineering to deployment, observability, and evaluation. Collaborate with data, infra, and product teams to scale serving for streaming and batch inference and improve models using dataset engineering and graph/embedding techniques.

Design and implement system-level debugging, validation, and observability platforms. Build automated anomaly collection/analysis, visualization and root-cause tools, failure classification and monitoring frameworks. Extend compilers, runtimes and programming interfaces for profiling and instrumentation, improve bring-up and low-level debug workflows, lead cross-functional initiatives, support incident response, and establish debuggability and reliability best practices.

Build and maintain data and model layers for an AI decision‑support system: data ingestion, probabilistic record matching, calibrated scoring, provenance‑tracked retrieval and grounded generation, and secure production pipelines. Ensure explainability, auditability, and accredited deployment in a controlled government cloud environment.

Design and build data and model layers for an accredited AI decision-support system: record matching, calibrated scoring, provenance-tracked retrieval and generation, secure ingestion pipelines, model packaging/serving, and instrumentation for audit and accreditation.

Build and operate model validation, quantization, and safety systems for production ML. Develop pipelines for security scanning, optimization (quantization/pruning), routing, prompt management, and evaluation frameworks measuring accuracy, performance, and safety across model lifecycles.

Lead design, development, and production deployment of ML models and GenAI/LLM solutions to optimize clinical trial workflows. Build scalable pipelines, monitoring, and CI/CD for robust production use. Collaborate cross-functionally, mentor junior engineers, and communicate technical results to technical and non-technical stakeholders.

Lead and mentor engineering teams while owning platform architecture (React, Node/Express, Postgres, AWS). Drive TypeScript migration, design ETL and AI/LLM integration frameworks, ensure reliability and observability, manage delivery, incidents, and hiring, and define technical strategy for production ML/AI systems.

Lead development and refinement of machine learning pricing models (especially reinforcement learning) for Airbnb hosts. Collaborate with data scientists, product, and engineers to design, test, integrate, and monitor models, analyze performance, and prioritize projects to improve host outcomes.

Lead a 4-6 engineer team owning the internal data warehouse and end-to-end ML Ops lifecycle: experimentation, training pipelines, deployment, and monitoring. Provide technical leadership, collaborate with cross-functional partners, define platform standards, and coach engineers to deliver reliable, scalable data and ML infrastructure that powers product analytics and identification features.

Build and prototype supervised ML models to predict ad campaign delivery outcomes (reach, frequency, contention). Own feature engineering, evaluation frameworks, interpretability, and partner with ML engineers to deploy and monitor models at scale. Collaborate across product, engineering, and sales to drive adoption and measure lift versus simulation baselines.

Lead the design and delivery of a production-grade localization ML stack for autonomous vehicles: architect models for landmark-based localization across sensors, own data and evaluation pipelines, drive feature development to deployment, define failure modes and safety coverage, and mentor engineers while integrating cutting-edge multimodal and foundation-model techniques into robust, real-time localization systems.