Top Senior Machine Learning Jobs in Kansas City, MO

Design, implement, and scale ML-based solutions for search and advertising; define data collection, evaluation, and production serving strategies; analyze data to inform development; communicate cross-functionally; produce technical reports; and stay current with advances in LLMs, vision models, and generative AI.

Own end-to-end production ML systems for search, recommendations, and ranking: architecture, training pipelines, inference, deployment, monitoring, drift detection, and retraining. Partner with data, product, and backend teams to ship reliable, low-latency ML-driven product experiences and set standards for ML infrastructure and model health.

Lead development and refinement of machine learning pricing models (especially reinforcement learning) for Airbnb hosts. Collaborate with data scientists, product, and engineers to design, test, integrate, and monitor models, analyze performance, and prioritize projects to improve host outcomes.

The Senior Machine Learning Engineer at Grailed will enhance personalization and recommendations, develop AI/ML solutions, and collaborate across departments for data-driven insights.

Industry Expert who reviews and defends advanced AI/ML and systems engineering projects, chairs architecture and executive review panels, hosts occasional technical sessions, and sets standards for instructors. The role requires production-scale engineering experience, live architecture critique, a public technical footprint, strong English, and expertise in agentic systems, LLM evaluation, model serving, cloud infrastructure, distributed systems, observability, RAG, and enterprise deployments.

Build and deploy LLM-powered agents, workflows, and production integrations using platform templates, pipelines, and guardrails. Develop and run evaluation suites, integrate business systems and data sources, instrument cost and quality telemetry, and collaborate with business users to iterate within bounded scopes. The role requires strong Python and TypeScript, API development, prompt and context engineering, and production experience with agents, RAG, and tool use.

Build and deploy LLM-powered agents and workflows using templates, pipelines, and guardrails. Develop comprehensive evaluations, integrate AI solutions with business systems and data sources, and instrument applications for cost and quality telemetry. Collaborate with business users to iterate within defined scopes. The role requires strong Python and TypeScript skills, production experience with LLM applications, API development, prompt and context engineering, retrieval, and healthcare data handling.

Own end-to-end ML lifecycle for pricing and underwriting: improve model accuracy and coverage, reduce infrastructure cost, deploy and monitor production models on AWS, run experiments/backtests, and collaborate with domain experts to inform model improvements and product APIs.

Build and operate production machine learning systems for Airbnb Payments, including LLM agents, real-time fraud detection, anomaly detection, personalization, and checkout optimization. Design, train, deploy, monitor, and continuously improve batch and streaming AI applications at global scale. Partner with product, engineering, operations, and data science teams, establish model governance and testing standards, and mentor engineers.

Lead development of new credit line management programs by designing, testing, and scaling policies. Own end-to-end analytical work using SQL/Python, partner with Data Science and Product, and present data-driven recommendations to senior stakeholders to improve spend recovery, utilization, and line-management performance.

Lead the integration of AI and digital solutions in manufacturing processes, driving adoption and measurable impact on efficiency, quality, and performance.

As a Senior Machine Learning Engineer, you will enhance diffusion models, conduct research, collaborate on system implementations, and communicate findings effectively.

The Principal Product Manager - Growth will lead growth initiatives, focusing on user engagement, retention, and the use of AI to enhance product strategies and experiences.

Design, build, and deploy machine learning systems for controlling quantum processors. Develop reinforcement learning and Bayesian methods for QEC calibration, and work cross-functionally with product and R&D teams.

The Senior Technical Architect will lead AI SDLC transformations, create architectural solutions, mentor teams, and drive innovation in regulated industries.

As a Regional Sales Director, you'll lead a sales team, develop business plans, and drive sales growth by managing complex cycles and nurturing talent.

Own the full lifecycle of production classification and detection models, including transformer fine-tuning, entity detection, behavioral risk scoring, training, serving, versioning, evaluation, drift detection, and retraining. Build SageMaker-based ML systems and define output contracts supporting audit and policy enforcement. Lead the evaluation harness and mentor a co-op while operating as the company’s sole ML engineer.

Designs, builds, documents, tests, and maintains large-scale data pipelines across platforms and sources. Performs ETL and ELT while ensuring data governance, security, quality, validation, anomaly detection, and compliance. Collaborates with architects, analysts, and stakeholders to translate business needs into technical solutions, develops data models, and mentors junior data engineers.

Own the full lifecycle of clinical text extraction models, from problem framing and annotation strategy through production deployment, evaluation, monitoring, and retraining. Build clinical NLP pipelines, establish defensible quality and error-analysis systems, and apply LLMs using rigorous evaluation, observability, and cost controls. Partner with clinical data and backend engineering teams while addressing PHI protection, de-identification, auditability, and access controls. As the first ML hire, set technical direction and potentially build and lead the future ML team.

Designs and operates production multi-agent AI systems, LLM workflows, scoring and optimization algorithms, and closed-loop autonomous processes. Responsibilities include AI model evaluation, production monitoring, governance, third-party AI integration, federated data retrieval, and identifying patentable inventions. The role requires deep machine learning expertise, algorithm development, and deployment experience across complex operational environments.

As a Machine Learning Engineer, you will design, build, and deploy ML models for underwriting at Stripe Capital, ensuring performance while collaborating with multiple teams.

Lead end-to-end product strategy and delivery for a core marketplace area, collaborating with engineering, UX, and design. Conduct qualitative and quantitative research, run agile sprints, measure results with analytics, and pioneer AI/ML product features and workflows to improve user experience and platform impact.

Lead go-to-market for Mapboxs AI products: define positioning, messaging, and launch strategy; drive customer research, sales enablement, content, and cross-functional alignment to accelerate adoption of AI-powered location capabilities.

Lead development and application of analytics, statistical models, and dashboards to support R&D Quality oversight. Integrate clinical, safety, lab, and operational data to identify risks, support audit/inspection readiness, enable RBQM, and provide actionable quality insights and recommendations to cross-functional partners.

Lead strategic vision and execution of next-generation bioinformatics technologies. Identify and evaluate emerging computational methods, translate research into production-grade pipelines and prototypes, support product roadmaps and technology transfer, and partner cross-functionally to commercialize genomic and AI-driven healthcare solutions.