Top Senior Machine Learning Jobs in Kansas City, MO

Drive net-new enterprise customer acquisition from lead generation through contract closure. Build C-level relationships, develop account strategies, manage CRM pipelines and forecasts, negotiate complex contracts, and close large AI, machine learning, and data talent engagements. Partner with marketing, customer success, and talent teams to deliver customer outcomes and expand Factored AI’s enterprise footprint.

Own the production lifecycle for machine learning and LLM-backed systems, including training and post-training pipelines, inference serving, model releases, monitoring, retrieval infrastructure, and cost and latency optimization. Partner with AI researchers and engineering teams to move prototypes into reliable production capabilities across customer tenants. Develop ETL and GraphQL features, enforce tenant isolation, and support deployments in regulated or customer-controlled environments.

Designs, deploys, and scales production AI agents and agentic workflows within enterprise Java and Spring applications. Establishes evaluation, monitoring, guardrail, safety, testing, observability, deployment, and operational standards for LLM systems. Leads architectural decisions across AI services and microservices, productionizes models, evaluates emerging technologies, mentors engineers, and influences technical strategy across teams.

Lead the design and implementation of large-scale AI and machine learning systems for Yahoo Search across multiple teams. Define data strategies, evaluation frameworks, and scalable production-serving approaches. Drive technical alignment among engineering, product, design, and research teams; guide adoption of large language models, vision models, generative AI, and agentic AI; and oversee data analysis informing strategic product decisions.

Build and operate scalable ML infrastructure and platform capabilities across cloud and on-premises environments. Develop Python-based developer tooling, services, and production systems supporting experimentation, distributed training, model deployment, and operations. Lead complex initiatives from architecture through rollout, improve reliability and developer productivity, and partner with ML and infrastructure teams. The role emphasizes Kubernetes, AWS, distributed compute, GPU-intensive workloads, observability, and production excellence.

You will tackle AI challenges, develop scalable software and collaborate with teams to enhance healthcare navigation using AI solutions.

Partner with functional leaders to translate business strategy into people strategy. Own org design, performance management, compensation, talent development, engagement, and retention. Provide coaching on career pathing, change management, and sensitive employee issues. Use people data to generate insights and recommendations, build compliant HR policies, manage global employee relations, and collaborate with People Team COEs to deliver cohesive people programs at scale.

Serve as second-in-command for Coinbase Derivatives' Market Regulation Department, leading day-to-day regulatory compliance, managing exams and audits, advising on CFTC Core Principles, reviewing surveillance escalations and enforcement actions, and coordinating cross-functional regulatory workstreams to ensure the DCM meets obligations and resolves findings timely.

Develop and maintain open-source Python frameworks and ML developer tools, architect scalable libraries, grow early-stage projects, build real-time streaming capabilities, integrate modern frontend technologies, and collaborate with open-source contributors and the broader developer community.

Drives operational excellence through data analysis, dashboards, process improvements, and cross-functional project leadership. The role embeds with business units to manage day-to-day operations, investigate trends, answer strategic questions, implement workflows, coordinate stakeholders, track deliverables, and present insights to technical and non-technical audiences. It serves as a strategic partner to operations leadership in a fast-paced, ambiguous environment.

Develop experimental AI techniques for agentic marketing applications, especially image and video generation. Build proofs of concept, autonomous evaluation and improvement systems, realistic AI-generated video, and brand-aligned creative generation workflows. The role requires strong quantitative and probabilistic thinking, backend architecture skills, creativity with LLM applications, and product intuition.

Drive MSSP partner growth across AMER by recruiting, onboarding, activating, and expanding strategic managed security service provider relationships. Develop territory recruitment plans, executive partnerships, joint business plans, and indirect routes to market. Help partners launch managed security services, generate pipeline, increase revenue, and accelerate time-to-revenue. Collaborate with sales, channel, marketing, services, and technical teams while managing forecasts, opportunities, executive reviews, and revenue objectives.

Lead the technical side of enterprise sales for autonomous systems and physical AI customers. Own discovery, architecture reviews, demonstrations, proofs of concept, evaluations, deployments, and expansions. Translate customer workflows into solutions, address technical objections, and collaborate with Product and Engineering. Build scalable sales engineering processes, technical content, evaluation frameworks, and operating models while supporting strategic automotive OEM and enterprise opportunities.

Lead product strategy, requirements, and roadmap development for Honeywell Forge cloud applications serving utilities. Own AI and analytics capabilities for grid operations, DER management, rate design, and utility programs. Conduct customer and market discovery, competitive analysis, and voice-of-customer research. Partner with solution architects, sales, customers, and engineering to prioritize and deliver B2B SaaS products that generate measurable utility operational value.

Lead product strategy, requirements, roadmap, and AI capabilities for Honeywell Forge cloud applications serving utilities. Conduct customer and competitive discovery, translate utility workflows into product investments, define commercial opportunities, and partner with engineering to prioritize and deliver cloud-native B2B software. The role focuses on AI for grid operations, DER management, rate design, and utility program performance while ensuring measurable operational value.

Lead technical direction for high-impact machine learning initiatives, from research and experimentation through production deployment. Build and fine-tune LLMs, document understanding systems, model-serving infrastructure, evaluation frameworks, and data feedback loops. Establish standards for model quality, calibration, reproducibility, and responsible deployment while mentoring ML engineers and influencing organizational roadmaps. The role requires hands-on software and ML engineering expertise, production-scale model development, and strong statistical judgment.

Own the global consumer engagement and personalization domain across digital channels. Assess current capabilities, define multi-year strategy and roadmap, recommend personalization infrastructure investments, and translate priorities into shipped products. Partner with engineering, data science, design, marketing, legal, and regional teams to deliver scalable experiences. Establish metrics, run cross-market experiments, optimize performance, and make global versus localized decisions. Influence executives, mentor product managers, and apply AI, identity resolution, and generative AI to personalization.

Manage the AI opportunity roadmap for Risk Services, prioritizing use cases, coordinating internal data science teams and external vendors, translating business needs into requirements, and supporting AI governance, compliance, explainability, auditability, implementation, adoption, and benefits realization. The role focuses on business outcomes and solution delivery rather than hands-on model development.

Own and develop SandboxAQ’s intellectual property function, including patent portfolio strategy, invention harvesting, prosecution, lifecycle management, outside counsel oversight, freedom-to-operate analyses, trademark clearance, and trade secret programs. Partner with scientists, engineers, and business teams to protect innovations, inform product strategy, support transactions, and build scalable IP processes in a fast-growing AI-focused company.

Manage paid media strategies and campaigns across search, social, display, and programmatic channels. Advise clients using integrated paid, organic, and analytics data; oversee campaign performance, keyword research, ad copy, landing page recommendations, and presentations. Build client relationships, mentor account associates, collaborate with SEO and data teams, and use AI to improve workflows and outcomes.

Develop and lead paid media strategies across search, social, display, and programmatic channels. Manage campaign strategy, performance analysis, testing, optimization, and integrated paid and organic recommendations. Consult with clients, present results, build relationships, mentor account associates, and identify data-driven growth opportunities. Use AI tools to improve workflows and contribute insights across the team.

Build and lead Nebius’s federal affairs function in Washington, D.C. Develop policy strategy across AI regulation, trade, energy, infrastructure, and national security; establish bipartisan relationships with Congress and executive agencies; represent the company in federal initiatives and coalitions; assess regulatory risks; coordinate with legal, communications, and infrastructure teams; manage outside lobbying partners; and hire staff as the function scales.

Lead research, architecture, and production deployment of large-scale algorithms for budget pacing, bid optimization, and marketplace balancing in Yahoo’s DSP. Apply control theory, optimization, and machine learning to real-time systems, while establishing AI-augmented research and engineering workflows. Own multi-quarter initiatives, define evaluation frameworks, guide technical strategy, collaborate with product and engineering leadership, mentor scientists and engineers, and communicate complex research and architectural decisions to executives.

Owns end-to-end development of datasets, reinforcement learning environments, and evaluations for coding agents and software engineering models. Leads engineers, researchers, QA professionals, and data creators; establishes quality processes, pipelines, validation, and review workflows. Collaborates directly with frontier AI labs, fine-tunes models, builds benchmarks, develops automation and internal tools, and supports customer-facing enablement. The role combines hands-on technical leadership, engineering management, operational execution, research, and industry thought leadership.

Lead the strategy, design, deployment, and scale-up of AI-powered health products across the Global South. Own product roadmaps, execution, government-system integration, stakeholder adoption, partnerships, grant development, and portfolio expansion. Collaborate with engineering, machine learning, program, and domain teams to deliver sustainable, measurable public-health impact.