Top Senior Software Engineer Jobs in Indianapolis, IN

Lead hands-on full-stack development for Ruby on Rails, TypeScript, and React applications. Shape technical direction, design reliable APIs and data flows, optimize relational database performance, and deliver responsive front-end experiences. Lead projects end to end, mentor engineers, review and refactor code, collaborate cross-functionally, and explore AI-assisted engineering and LLM automation while protecting sensitive healthcare data.

Leads the design, development, deployment, maintenance, and support of scalable web applications. Responsibilities include coding, debugging, code reviews, API-first development, performance optimization, testing, cloud-native deployments, database and caching strategy, production monitoring, incident response, mentoring engineers, and cross-functional collaboration with product, design, customers, and vendors.

Design and scale platform infrastructure, backend services, developer tooling, CI/CD pipelines, and secure cloud-native systems. Improve developer experience, reliability, observability, and incident response while establishing security and compliance controls. Partner with engineering and product leaders to shape architecture and platform strategy, mentor engineers, and support customer-facing logistics projects. The role uses Python, AWS, Terraform, containers, orchestration, event-driven architectures, and relational databases.

Lead design and implementation of Headway's insurance systems (eligibility, pricing, matching, claims). Build data-intensive, ML-powered platforms and automation, mentor engineers, write high-impact code, and improve accuracy and reliability across state and payer complexity to scale insurance-covered therapy.

Designs and develops scalable customer-facing web applications and microservices APIs. Leads complex system architecture, performs code reviews, mentors engineers, defines technical implementations, and guides engineering vision. Maintains sustainable business systems, supports compliance initiatives, and improves development processes. The role requires Java and Spring experience, cloud technologies, relational databases, REST and event-driven architectures, containerization, front-end development, and software lifecycle expertise.

Lead quality engineering for a backend-heavy Immigration AI platform. Design test plans and cases, establish test environments, execute manual and automated testing, build custom frameworks and tooling, and test REST, asynchronous, event-driven, and backend services. Mentor engineers, conduct code reviews, identify automation opportunities, apply GenAI and LLMs, perform load and stress testing, and improve testing pipeline scalability, performance, and efficiency.

Leads Node.js sub-team architecture, technical standards, and complex full-stack development across frontend, mobile, and backend platforms. Builds React, TypeScript, Next.js, React Native, and Node.js features; designs APIs, authentication, caching, and data models; mentors engineers; and owns performance, testing, CI/CD, security, scalability, and HIPAA-compliant delivery.

Lead end-to-end feature development across frontend and backend for an enterprise data analytics platform. Design, implement, and maintain React UIs, backend services, APIs, databases, and distributed systems. Collaborate with Product, UX, and Engineering, mentor engineers, improve quality through testing/CI, and introduce new technologies including AI-assisted development.

Build and maintain on-chain smart contracts and backend services for branded USDC-backed stablecoins. Own issuance, reserves, mint/burn, and rewards systems; drive architecture, security, and operational excellence; ship features with product and design partners and ensure well-tested, auditable production deployments.

Own quality engineering for high-throughput payment systems by architecting automated regression, performance, stress, and load testing. Build emulators for external payment systems, integrate quality gates into CI/CD pipelines, validate microservices, event-driven architectures, and databases, and use Prometheus and Grafana for observability. Apply AI-assisted testing, synthetic data generation, and edge-case analysis while mentoring engineers and preventing incidents through telemetry-driven testing and post-mortems.

Build and scale ML-optimized HPC infrastructure, manage Kubernetes-based GPU/TPU superclusters, optimize for AI/ML training, and mentor teams while innovating in ML infrastructure.

Build and maintain reliable, secure, scalable backend systems for Lithic’s product platform. Own projects end to end across API key management, reliability, audit logging, search, and API infrastructure. Improve system reliability, reduce technical debt, participate in on-call rotations, and lead team process improvements while collaborating asynchronously across time zones.

Build and operate highly scalable storage infrastructure supporting petabyte-scale imagery data. Responsibilities include developing backend services and APIs, managing object storage and metadata indexing, tuning Elasticsearch, improving disaster recovery, monitoring performance, responding to incidents, contributing to architecture and roadmaps, and advising engineers. The role requires strong production software engineering experience with Go or Python, cloud-native systems, relational and non-relational databases, and highly available services.

Lead technical strategy and architecture for Affirm Bank's cloud, data, vendor integrations, and operational tooling. Design, build, and operate high-stakes systems end-to-end, own incident response, vendor selection, and the Bank↔Affirm Inc integration boundary. Ensure examiner-ready documentation, compliance, reliability, and observability while mentoring engineers and pushing AI-assisted engineering practices to increase velocity and product safety.

Build and improve frontend interfaces for DogByte and other internal products used by veterinary hospitals. Own projects from problem framing through production release, collaborate with Design and Product, uphold accessibility and performance standards, evolve shared components and design systems, review technical work, and contribute to backend or full-stack development as needed. Apply AI tools thoughtfully across development workflows while maintaining quality and reliability.

Lead architecture and implementation of software for autonomous UAS systems; mentor engineers; ensure compliance with aerospace standards; optimize CI/CD pipelines.

Develop and enhance the new Stores platform while supporting various e-commerce tools to improve seller success online.

As a Senior Fullstack Software Engineer at Vanta, you will lead complex projects, set technical direction, design and develop new functionalities, and contribute to the engineering culture while mentoring other engineers.

The Software Engineer will develop and support the MEMX Trading system, focusing on high throughput event-sourcing applications and resolving production issues.

Seeking experienced Senior Backend Engineers to join a collaborative team, focusing on backend systems, shared services, and product features aimed at improving user experiences and monetization.

The Senior Full Stack Software Engineer will oversee technical development in a B2B SaaS healthcare environment, mentor junior engineers, and lead product features.

The Senior Web Software Engineer will build and maintain web components, own features from inception to production, implement designs, partner with teams, and impact product evolution.

As a Senior Backend Software Engineer at Step, you'll own features from inception to production, improve Kotlin services, ensure code quality, and work collaboratively in a small team.

The Senior Mobile Software Engineer will develop user-facing features for a cross-platform app, ensuring code quality and functionality throughout the entire lifecycle of features.

Design, implement, and ship end-to-end features across backend services and a React web client for a multi-tenant ERP. Own schema design, migrations respecting row-level security, integrations with platform services, and deliver high-quality, performant code with CI/CD, tests, and code review. Leverage AI coding assistants responsibly and collaborate cross-functionally to evolve shared platform libraries and developer tooling.