Top Senior Software Engineer Jobs in Indianapolis, IN

Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
225K-265K Annually
Senior level
225K-265K Annually
Senior level
Software
The Senior Software Engineer will enhance patient experiences by developing modern software for doctor's offices, contributing to product features, and participating in client feedback.
Top Skills: AILinuxPostgresPython
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
140K-200K Annually
Senior level
140K-200K Annually
Senior level
Big Data • HR Tech • Mobile • Software • Database
The role involves building data processing pipelines, deploying cloud technologies, and writing code in a Kubernetes environment, focusing on big data technologies.
Top Skills: Amazon Kinesis Data AnalyticsApache BeamApache FlinkApache HudiApache KafkaAzure DatabricksCassandraDelta LakeDockerFlumeGoogle Cloud DataflowHadoopHbaseHiveKubernetesMongoDBNifiSpark
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
250K-300K Annually
Senior level
250K-300K Annually
Senior level
Software
The Staff Software Engineer will upgrade patient experience by developing features for a healthcare software platform, leading the product development throughout the process.
Top Skills: AILinuxPostgresPython
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
140K-200K Annually
Senior level
140K-200K Annually
Senior level
Software
As a Senior Software Engineer, you will design and optimize APIs, develop cloud functions, and collaborate with product teams to enhance user experiences at Speechify.
Top Skills: GCPKotlinKotlin Multiplatform
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Software
The Senior Software Engineer will build and maintain foundational services and SDKs, optimize functionality, and collaborate on product solutions using Kotlin.
Top Skills: GCPKotlinKotlin Multiplatform
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Information Technology • Consulting
Design, develop, and optimize data infrastructure, focusing on GCP, ETL/ELT workflows, and data governance, while collaborating with cross-functional teams.
Top Skills: Apache AirflowDatabricksDataformDbtFivetranGCPPythonSparkSQL
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
200K-225K Annually
Senior level
200K-225K Annually
Senior level
Healthtech • Telehealth
Lead the development of product features, mentor engineers, optimize system architecture, and ensure best practices in a high-performance team.
Top Skills: Ant DesignHerokuNestjsNext.JsNode.jsPostgresReactRedisTypeormTypescript
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
195K-220K Annually
Senior level
195K-220K Annually
Senior level
Healthtech • Software
As a Senior Software Engineer, you will develop efficient systems to enhance healthcare delivery and collaborate with various teams to innovate features for patient care tools.
Top Skills: CGoJavaPythonRuby
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
180K-245K Annually
Senior level
180K-245K Annually
Senior level
Software
Lead design and implementation of scalable APIs and agent communication layers for an AI-agent driven advertising marketplace. Build high-throughput backend systems, integrate agent frameworks and adtech partners, drive architecture for authentication and protocols, mentor engineers, and prototype agent communication patterns while collaborating with product and design.
Top Skills: A2A ProtocolsAi Agent FrameworksAuth/VersioningAWSBigQueryCloud StorageEvent-Driven ServicesGCPMcp ServersNode.jsPostgresReactRedisRestTypescript
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Artificial Intelligence • Machine Learning • Natural Language Processing • Software
As a Staff Software Engineer, you will architect and build high-impact systems, mentor engineers, solve complex technical challenges, and lead cross-organizational initiatives in a fast-paced AI infrastructure environment.
Top Skills: AWSAzureGCPIacKubernetes
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
200K-250K Annually
Senior level
200K-250K Annually
Senior level
Blockchain
Design and build core systems for a new application using Solana's infrastructure. Focus on low-latency, reliable services, and implement security measures.
Top Skills: CC++GoRustSolana
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
170K-300K Annually
Senior level
170K-300K Annually
Senior level
Fintech • Software
Build and operate full-stack, production-ready systems: design and ship AI-native mortgage automation, integrate third-party lending APIs, and architect scalable AWS infrastructure and job processing. Mentor engineers and ensure security, observability, and high reliability.
Top Skills: ApolloAWSCloudFormationDockerEcsElasticacheElasticsearchExpressGraphQLKafkaLlmsNode.jsPostgresRdsReactTerraformTypescript
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Reposted 2 Days AgoSaved
Remote or Hybrid
Indianapolis, IN
Senior level
Senior level
Artificial Intelligence • Software • Cybersecurity
The Staff Software Engineer will lead technical vision and execution, drive architectural decisions, mentor engineers, and ensure code quality and scalability.
Top Skills: AWSDockerGCPGoKubernetesMySQLNext.JsPostgresPythonReactTypescript
Reposted 2 Days AgoSaved
Remote or Hybrid
Indianapolis, IN
Senior level
Senior level
Artificial Intelligence • Software • Cybersecurity
Design and develop scalable backend services and APIs, building frontend applications, collaborating on features, and ensuring system reliability. Lead technical projects and improve engineering practices.
Top Skills: AWSDockerGCPGoKubernetesMySQLNext.JsPostgresPythonReactTypescript
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
121K-163K Annually
Senior level
121K-163K Annually
Senior level
Information Technology • Software
The Senior Software Engineer will design and develop IMS TM and DB-compatible technologies, providing architectural leadership and mentoring while optimizing mission-critical applications for modern environments.
Top Skills: AWSAzureCC++CobolIbm ImsKubernetesPl/IZ/Os
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Software
As a Senior Software Engineer, you will design and develop backend systems, optimize application performance, and mentor team members while building intuitive front-end features.
Top Skills: AWSDockerJavaPostgresReactSQLTerraformTypescript
Reposted 2 Days AgoSaved
In-Office or Remote
Indianapolis, IN
121K-219K Annually
Senior level
121K-219K Annually
Senior level
Cloud • Security • Software • Cybersecurity
The Senior Software Engineer will manage Akamai's cloud storage solution, lead system design, development, and support, collaborating with various teams to enhance product offerings.
Top Skills: CouchdbGitLinuxNoSQLPerlPythonShellStashUnix
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
195K-229K Annually
Senior level
195K-229K Annually
Senior level
Software
Join Vanta as a Senior Software Engineer to lead and mentor teams, driving projects on identity systems and improving security infrastructure.
Top Skills: OidcPolicy-Based Access ControlRbacSAML
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
190K-270K Annually
Senior level
190K-270K Annually
Senior level
Artificial Intelligence
Design and build scalable backend components and indexing pipelines for semantic and hybrid retrieval, build retrieval orchestration and knowledge-graph services, improve retrieval quality via evaluation and observability, design APIs, and optimize latency, throughput, cost, reliability, and security for large-scale AI inference and retrieval workloads.
Top Skills: C++ElasticEmbeddingsGoHybrid RetrievalJavaKnowledge GraphKubernetesLlmsObservability FrameworksOpensearchPineconePulumiPythonRagRustSemantic SearchTerraformVector Databases
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
165K-185K Annually
Senior level
165K-185K Annually
Senior level
Digital Media • Professional Services • Consulting • Financial Services
Own server-side and infrastructure for Fool.com using Next.js and TypeScript. Build route handlers, server components, API integrations, caching (Redis/Cloudflare), AWS/Docker deployments, observability with DataDog, and end-to-end tests with Playwright. Optimize SEO crawler surface, sitemaps, canonicalization, and collaborate with front-end, content, and platform teams.
Top Skills: AWSCi/CdClaude CodeCloudflareCmsCursorDatadogDockerNext.JsPlaywrightRedisTypescript
Reposted 2 Days AgoSaved
In-Office or Remote
Indianapolis, IN
135K-170K Annually
Senior level
135K-170K Annually
Senior level
Biotech
The Senior Software Engineer will design and develop scalable digital healthcare solutions, integrating AI capabilities and collaborating cross-functionally while leading technical initiatives in software development.
Top Skills: AWSAzureGCPNext.JsNode.jsPythonReact
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
128K-267K Annually
Senior level
128K-267K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
As a Senior Software Engineer, you will develop and optimize high-performance APIs, ensuring reliable, low-latency access to user data and collaborating closely with various teams on essential API infrastructure.
Top Skills: AWSBigQueryComposerDataflowGCPGkeGoGrpcJavaJwtOauth 2.0PythonRedisRest ApiSpanner
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
144K-299K Annually
Senior level
144K-299K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
As a Principal Software Dev Engineer, lead full-stack engineering, oversee complex initiatives, mentor engineers, and align technical strategies with business goals to enhance content management systems.
Top Skills: AIAWSCloud TechnologiesFastapiLarge Language ModelsNext.JsPythonReactTypescript
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Automotive
As a Senior Software Engineer (Backend), you will design and implement scalable applications, collaborate with agile teams, and mentor junior members while ensuring high code quality and performance.
Top Skills: AWSJavaJavaScriptMySQLReactSpring
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
150K-175K Annually
Senior level
150K-175K Annually
Senior level
Information Technology
As a Senior Software Engineer, you will architect and implement Python-based systems, lead feature design and delivery, ensure scalability and reliability, and mentor junior engineers.
Top Skills: Aws CloudPostgresPythonRestful Apis
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