Top Senior Machine Learning Jobs in Charleston, SC

Reposted 3 Days AgoSaved
Remote
Charleston, SC
164K-205K Annually
Senior level
164K-205K Annually
Senior level
Automotive • Insurance • Machine Learning • Mobile • Software
As a Lead Machine Learning Engineer at Root, you'll build scalable ML systems, partner with data scientists, and improve operational practices for customer lifetime value modeling.
Top Skills: AirflowAWSAzureDagsterDatabricksDbtGCPMlflowPythonSnowflakeSparkTerraform
Reposted 3 Days AgoSaved
Remote
Charleston, SC
158K-208K Annually
Senior level
158K-208K Annually
Senior level
Biotech
Lead the strategy and implementation of AI solutions in R&D, driving adoption and improving operational efficiency through advanced analytics. Collaborate with cross-functional teams to design AI/ML models and evaluate new technologies.
Top Skills: AWSAzureDatabricksNumpyPandasPower BIPythonPyTorchRR ShinySASScikit-LearnSQLTensorFlow
Reposted 4 Days AgoSaved
Remote
Charleston, SC
165K-185K Annually
Senior level
165K-185K Annually
Senior level
Cloud • Software
The role involves leading ML client engagements, shaping strategies, advising on ML architecture, and influencing project outcomes, while guiding teams and driving business value.
Top Skills: Amazon KinesisApache KafkaSparkAWSDockerGenaiHuggingfaceJaxKubeflowKubernetesLlmopsMlMlflowMlopsPysparkPyTorchScikit-LearnTensorFlowXgboost
Reposted 4 Days AgoSaved
Remote
Charleston, SC
140K-215K Annually
Senior level
140K-215K Annually
Senior level
Cloud • Software
The AI/ML Engineering Manager leads a team of ML engineers and architects, managing hiring, performance, and customer engagements while providing technical guidance in ML operations and architecture.
Top Skills: Amazon Web Services (Aws)Apache KafkaSparkDockerHuggingfaceKubernetesMlflowPysparkPyTorchSagemakerScikit-LearnTensorFlow
Reposted 4 Days AgoSaved
In-Office or Remote
Charleston, SC
92K-203K Annually
Senior level
92K-203K Annually
Senior level
Information Technology
The AI Strategist leads AI initiative ideation and planning, collaborates across departments to define use cases, and ensures alignment with strategic and regulatory goals.
Top Skills: Adobe FireflyAgentspaceAws BedrockConfluenceFaissHaystackLangchainLanggraphMiroModel-Context ProtocolN8NPineconePortkeyPostgresSharepointSupabase
Reposted 4 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Gaming • Software
As a Senior ML Engineer, you'll own ML-driven features from modeling to deployment, drive innovation in generative AI, and mentor junior members.
Top Skills: AILlmsMlMlops
Reposted 4 Days AgoSaved
Remote
Charleston, SC
159K-219K Annually
Senior level
159K-219K Annually
Senior level
Artificial Intelligence • Big Data • Cloud • Information Technology • Machine Learning
As a Senior AI Engineer, you will develop and optimize Generative AI applications, manage AI pipelines, collaborate with clients, and ensure production delivery with MLOps best practices.
Top Skills: GCPGoogle GeminiGpt-4LangchainLlamaindexPgvectorPythonVector Databases
4 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Information Technology • Consulting
Design and improve ML training frameworks, modularize experiments, adapt fire-hazard detection algorithms for varied electrical environments, build scalable pipelines for high-frequency sensor data, and develop dashboards and tooling to monitor model performance and drift while collaborating across product, data science, and fire safety teams.
Top Skills: GitLinuxMakePythonShell ScriptingSsh
Reposted 4 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Payments • Software
As a Machine Learning Engineer, you will design, build, and deploy ML models for underwriting at Stripe Capital, ensuring performance while collaborating with multiple teams.
Top Skills: PyTorchSparkTensorFlowXgboost
Reposted 4 Days AgoSaved
Remote
Charleston, SC
165K-210K Annually
Senior level
165K-210K Annually
Senior level
Marketing Tech
Lead a team of data scientists developing ML-driven products, managing infrastructure, training models, and ensuring production quality while collaborating with senior leadership.
Top Skills: DockerJaxKubernetesPythonPyTorchSQLTensorFlowTerraform
Reposted 4 Days AgoSaved
Remote
Charleston, SC
185K-215K Annually
Senior level
185K-215K Annually
Senior level
Software
The role involves designing, training, and evaluating ML models, optimizing performance, and collaborating with teams to implement AI technologies in products.
Top Skills: KubeflowMlflowPythonPyTorchTensorFlowWeights & Biases
Reposted 5 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Machine Learning • Software
Lead and grow the AI/ML Engineering team, manage core AI/ML platform development, ensure production-grade service operational excellence, and develop product strategies.
Top Skills: AIJavaMlPythonRustScala
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29 Days AgoSaved
Remote
Charleston, SC
225K-255K Annually
Senior level
225K-255K Annually
Senior level
Security
The Sr. Director, Marketing Planning & Transformation will lead integrated marketing strategies and AI execution, optimize marketing operations, and drive team success in a fast-paced environment.
Top Skills: AIGenerative AiHubspotMachine LearningMarketoPredictive AnalyticsSalesforce
Reposted 6 Days AgoSaved
In-Office or Remote
Charleston, SC
150K-300K Annually
Senior level
150K-300K Annually
Senior level
AdTech • Artificial Intelligence • Information Technology • Mobile • Software
The Senior Machine Learning Engineer will design, train, and deploy ML models for optimizing revenue in advertising, taking ownership of product development and leading the ML discipline.
Top Skills: AWSClickhouseDatadogGoKubernetesLightgbmOnnxPythonXgboost
Reposted 6 Days AgoSaved
Remote
Charleston, SC
205K-270K Annually
Senior level
205K-270K Annually
Senior level
Artificial Intelligence • Other • Sales • Software
The role involves developing and optimizing machine learning systems for voice experiences, focusing on speech recognition and language understanding. Responsibilities include training models, ensuring performance metrics, and collaborating with cross-functional teams for successful deployment.
Top Skills: Hugging FacePyTorchTensorFlow
Reposted 6 Days AgoSaved
Remote
Charleston, SC
178K-198K Annually
Senior level
178K-198K Annually
Senior level
Healthtech • Software
The role involves applying AI/ML techniques to develop model systems for healthcare, collaborating across teams, and conducting R&D.
Top Skills: SparkAWSAzureAzure Data LakeDatabricksGCPHugging Face TransformersJavaLightgbmNumpyPandasPythonPyTorchScikit-LearnScipySQL
Reposted 6 Days AgoSaved
Remote
Charleston, SC
220K-270K Annually
Senior level
220K-270K Annually
Senior level
Automotive • Machine Learning • Robotics • Software • Transportation
The Lead Machine Learning Engineer will design and evaluate models for autonomous driving systems, mentor junior engineers, and utilize large datasets to improve ML capabilities at May Mobility.
Top Skills: CameraLidarLinuxPythonPyTorchRadar
7 Days AgoSaved
Remote
Charleston, SC
163K-218K Annually
Senior level
163K-218K Annually
Senior level
Internet of Things
Design, fine-tune, evaluate, and deploy LLM-driven, user-facing browser features using RAG, embeddings, prompt engineering, and modern ML tooling. Lead end-to-end model lifecycle, run production experiments, collaborate with product and engineering, and document and review work with an emphasis on privacy, latency, and usability.
Top Skills: Browser Web TechnologiesClassificationEmbedding-Based RetrievalGenerative AiHugging FaceIntent ModelingLangchainLarge Language Models (Llms)Natural Language Processing (Nlp)On-Device Model OptimizationPrivacy-Preserving MlPrompt EngineeringRayRetrieval-Augmented Generation (Rag)SummarizationWeights & Biases
Reposted 7 Days AgoSaved
Remote
Charleston, SC
175K-220K Annually
Senior level
175K-220K Annually
Senior level
Artificial Intelligence • Fintech • Machine Learning • Software • Financial Services
Lead the development of device intelligence and fingerprinting systems by designing backend services, collaborating on integrations, and applying advanced machine learning algorithms to enhance security and combat fraud.
Top Skills: AWSAzureDockerGoGCPKubernetesPyTorchScikit-LearnSQL
Reposted 7 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Machine Learning • Software
Develop, evaluate, and deploy AI systems and machine learning models, focusing on NLP and multimodal models. Collaborate with teams and publish research.
Top Skills: Information RetrievalLarge Language ModelsNatural Language ProcessingPandasRetrieval-Augmented GenerationTorchTransformersTransformers
Reposted 7 Days AgoSaved
Remote
Charleston, SC
180K-200K Annually
Senior level
180K-200K Annually
Senior level
Artificial Intelligence • Software
The Senior ML Engineer will automate component placement on PCBs, working on R&D and production using ML and optimization techniques.
Top Skills: Cuda C++PyTorch
Reposted 7 Days AgoSaved
Remote
Charleston, SC
180K-200K Annually
Senior level
180K-200K Annually
Senior level
Artificial Intelligence • Software
As a Senior/Staff ML Systems Engineer at Quilter, you'll design and maintain ML infrastructure for automated PCB component placement, manage data pipelines, and lead systems design reviews while ensuring project efficiency and reliability within a fully distributed team.
Top Skills: AICi/CdHigh-Performance ComputingMl
Reposted 7 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Artificial Intelligence • Other • Sales • Software
As a Senior Machine Learning Engineer, develop LLM evaluation frameworks and agentic AI workflows to extract insights from conversations and optimize customer experiences.
Top Skills: Hugging FaceLlmNlpNltkPyTorchSpacyTensorFlow
8 Days AgoSaved
Remote
Charleston, SC
119K-217K Annually
Senior level
119K-217K Annually
Senior level
Kids + Family • Mobile
Build and operate high-throughput experimentation and recommendation infrastructure. Design APIs and services, use agentic AI workflows (LLMs) for development, ensure performance and reliability, participate in on-call, mentor teammates, and codify AI-native engineering practices.
Top Skills: Apache KafkaAWSClaude CodeConfluent CloudConfluent PlatformContainerized DeploymentsCursorDatadogFeature StoresFlinkGithub ActionsGithub CopilotGrafanaJavaKafka StreamsLlmsMavenNexusPrometheusSchema RegistrySpring Boot
8 Days AgoSaved
Remote
Charleston, SC
196K-227K Annually
Senior level
196K-227K Annually
Senior level
Real Estate • Travel • PropTech
Lead development of cutting-edge LLM and Agentic AI systems for Airbnb customer support, from research and prototyping to production deployment. Collaborate with product, design, and engineering to build scalable ML infrastructure, improve model performance, and implement evaluation, fine-tuning, and guardrails for chat and voice assistants.
Top Skills: Agentic AiAutogenDistillationGrpoLanggraphLlmLlm Evaluation FrameworksMl InfrastructureMlopsModel ServingMulti-Agent OrchestrationPretrainingPrompt EngineeringRagReactRlhfSft
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