Top Senior Machine Learning Jobs in Charleston, SC

As Director of AI/ML, lead the ML organization, set technical vision, mentor a high-performing team, and contribute to model development and production deployment.

The AI & Data Science Director will lead AI strategies, foster technical leadership, support team development, and integrate generative AI into products.

Lead high-impact strategy and BizOps workstreams including M&A diligence, investor relations, new-market expansion, and cross-market operations. Frame ambiguous, board-level problems, build analysis and recommendations, align stakeholders, and own execution end-to-end while leveraging AI and automation.

The AI Sales Executive drives new business growth and expands client relationships by selling AI-driven solutions for engineering and manufacturing sectors, managing the full sales cycle with a consultative approach.

The Senior Generative AI Engineer will design and deploy AI/ML solutions, focusing on Generative AI systems and their operational excellence across various sectors like R&D and Clinical Trials.

The Technical Product Owner will lead product initiatives by defining requirements, managing the product backlog, and ensuring successful payment integrations while collaborating with engineering and risk teams.

This role involves leading strategic planning, product innovation, and cross-functional collaboration to enhance pharmacy analytics and drive growth initiatives for CVS Health.

Conduct ML research for query understanding, ranking, clustering, and AI-powered search. Prototype and productionize algorithms, define data and evaluation requirements, design scalable systems, collaborate with engineers, run experiments, and publish patents/papers to integrate state-of-the-art ML into Yahoo Search products.

Design and deploy production recommendation and retrieval engines, build data orchestration pipelines for multiple modalities, implement agentic workflow frameworks, and prototype, optimize, and scale models with monitoring, governance, and low-latency SLAs.

Lead design, training, fine-tuning, and deployment of ML and generative models (LLMs, diffusion). Build scalable MLOps pipelines, vectorization and data ingestion, integrate models into microservices for low-latency inference, implement evaluation/alignment/bias-mitigation, optimize models (quantization, distillation), and mentor engineers while influencing the AI product roadmap.

As a Senior Machine Learning Engineer, you will design and maintain ML systems for content recommendations, search, and spam detection, while augmenting user experience and system performance.

Design real-world ML and NLP tasks, build reference solutions and evaluation frameworks in Python, assess LLM outputs for correctness and reasoning, identify failure modes, create scoring rubrics, and collaborate with experts to improve model capabilities. Part-time, remote contractor (~20 hours/week).

Lead design and delivery of scalable AI systems for autonomous threat detection and response. Build and productionize LLMs, graph reasoning engines, streaming feature pipelines, and orchestration frameworks. Own evaluation, reliability, and cross-functional collaboration while mentoring engineers and experimenting with RAG, tool-calling agents, and multi-modal models.

The AI/Machine Learning Engineer will develop systems for automating health benefits decisions, integrating large language models with rule-driven patterns, and ensuring compliance with regulations.

Lead design, development, and productionization of advanced ML models and data pipelines. Drive architecture, experimentation, validation, and best practices while mentoring ML engineers and delivering scalable, business-driving AI solutions.

Lead architecture and delivery of scalable, production-grade ML/AI platforms and Python SDKs. Design Agentic AI and multi-agent systems, build FastAPI services, implement CI/CD, observability with Galileo, mentor engineers, and troubleshoot distributed AI systems for high availability and performance.

The Machine Learning Engineer will develop software solutions, optimize data pipelines, and deploy machine learning models using cloud platforms and best practices.

Design, build, and deploy high-throughput ML and LLM-powered personalization and agentic systems at consumer scale. Process petabyte-scale data, optimize real-time inference, implement resilient fallback paths, and balance latency, cost, and model quality while collaborating across engineering and product teams.

Lead a team to develop groundbreaking technology combining NLP, big data, and AI to enhance digital communication and interaction.

The GTM role focuses on increasing revenue through new sales and partnerships, understanding client needs, and communicating product value.

Design, build, and scale low-latency distributed platform components; define technical vision and architecture; collaborate with product and ML teams; evaluate build-vs-buy decisions; prototype research breakthroughs and deliver robust, production-grade services.

Lead full-cycle enterprise sales into Fortune 500 retailers, marketplaces, and travel companies. Manage eight-figure deals with C-suite and technical buyers, coordinate internal resources, build procurement-ready ROI/business cases, run pilots/A-B tests, and drive land-and-expand growth while shaping GTM playbooks.

Lead definition and delivery of AI-powered capabilities for a sustainability real-estate data platform. Shape roadmap, partner with customers and data science, own end-to-end features, define evaluation and trust frameworks, and ensure data foundations support AI. Drive cross-functional alignment and use AI tools in product workflow.

Lead design and implementation of real-time, event-driven data ecosystems powering personalization. Define self-service data infrastructure, governance, and architecture standards. Provide cross-team technical oversight, mentor engineers, ensure production reliability and cost optimization, participate in deployments and on-call, and collaborate on roadmaps and OKRs.

Lead credit analytics for the Send Now Pay Later product: build and own valuation and vintage models, manage credit policies, monitor portfolio health and NPL trends, integrate ML scorecards, and evaluate alternative data to optimize approvals and loss performance.