Top Senior Data Science Jobs in Charleston, SC

Reposted 21 Hours AgoSaved
Remote
Charleston, SC
170K-272K Annually
Senior level
170K-272K Annually
Senior level
Cloud • Fintech • Food • Information Technology • Software • Hospitality
Lead design and delivery of scalable ML systems across the full lifecycle for recommendations, demand forecasting, targeting, and personalization. Collaborate with engineers, product, and stakeholders to set architecture, metrics, and production best practices; mentor data scientists; lead experimentation and deploy/monitor models using cloud and MLOps tooling.
Top Skills: AthenaAWSBedrockDistributed Data ProcessingDynamoDBGlueLlm Fine-TuningMlopsPythonPyTorchReal-Time InferenceRlhfSagemakerScikit-LearnSQLTensorFlow
Reposted 21 Hours AgoSaved
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Remote
Charleston, SC
Easy Apply
236K-295K Annually
Senior level
236K-295K Annually
Senior level
Artificial Intelligence • Enterprise Web • Information Technology • Productivity • Sales • Software • Database
Lead product analytics to inform strategy and optimize user experience: translate business questions into analysis, build reliable analytics infrastructure, run A/B tests and ML/statistical analyses, track funnels and cohorts, support 0-to-1 product launches, and communicate actionable insights to cross-functional teams.
Top Skills: A/B TestingAmplitudeHeapLookerMachine LearningMixpanelPythonRSASSQLStatistical Analysis
YesterdaySaved
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Remote or Hybrid
Charleston, SC
Easy Apply
160K-194K Annually
Senior level
160K-194K Annually
Senior level
Artificial Intelligence • Insurance • Machine Learning • Software • Analytics
Lead complex modeling projects combining deep learning, LLMs, and traditional techniques. Prototype, deploy, and monitor production models, mentor data scientists, collaborate with engineering/product, and translate results into business impact for insurance customers.
Top Skills: APIsBig DataCi/CdDockerExperiment TrackingFederated LearningGlmJupyterLlmsMlopsModel ServingNeural NetworksPipeline OrchestrationPythonTime Series ModelingTransformersXgboost
12 Days AgoSaved
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Remote
Charleston, SC
Easy Apply
207K-244K Annually
Senior level
207K-244K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Lead end-to-end pricing experimentation and strategy for consumer and business products. Design and analyze A/B tests, build pricing models and production-grade data pipelines, partner cross-functionally, and present actionable recommendations to senior leadership.
Top Skills: Generative AiPythonRSQL
Reposted 18 Days AgoSaved
Remote
Charleston, SC
200K-240K Annually
Senior level
200K-240K Annually
Senior level
Fintech • Information Technology • Software
As a Staff Data Scientist at SentiLink, you will develop fraud detection models, conduct analyses, collaborate across teams, and drive the development of financial risk products.
Top Skills: AWSPostgresPython 3
Reposted 21 Hours AgoSaved
Remote
Charleston, SC
160K-220K Annually
Senior level
160K-220K Annually
Senior level
Fintech • Financial Services
Lead and deliver end-to-end data science projects: design, build, deploy, and monitor ML/statistical models for credit risk, pricing, collections, and fraud. Partner with cross-functional teams to integrate models into production, set model development standards, mentor engineers, and maintain reliable ML pipelines and monitoring systems.
Top Skills: AWSGitPythonSagemakerSQL
Reposted 21 Hours AgoSaved
Easy Apply
Remote
Charleston, SC
Easy Apply
180K-212K Annually
Senior level
180K-212K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Own and evolve revenue calibration models tying CX interactions to revenue, design causal inference and experimentation frameworks, build LLM-powered classification/NLP pipelines, productionize models with Analytics Engineers, define segmentation and behavioral signals, and ensure statistical rigor for executive reporting and regulatory defensibility.
Top Skills: A/B TestingCausal InferenceGeminiGenerative AiGleanLibrechatLlmMlNlp
YesterdaySaved
Remote or Hybrid
Charleston, SC
151K-323K Annually
Senior level
151K-323K Annually
Senior level
Consumer Web • Coupons • Healthtech • Social Impact • Pharmaceutical
Lead and deliver productionized ML solutions across audience, marketing, pharma direct, and employer analytics. Design segmentation, propensity, attribution, and identity models; apply causal inference and experimentation; operationalize models with MLOps; evaluate generative AI/LLM use cases; set technical roadmap and mentor data scientists to drive measurable business impact.
Top Skills: AWSAzureDatabricksEmrExperimentation PlatformsFeature StoreGCPGenerative AiLlmsMlopsModel MonitoringNumpyPandasPostgresPysparkPythonPyTorchRedshiftScikit-LearnSparkTensorFlow
YesterdaySaved
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Remote or Hybrid
Charleston, SC
Easy Apply
190K-235K Annually
Senior level
190K-235K Annually
Senior level
Artificial Intelligence • Insurance • Machine Learning • Software • Analytics
Lead high-impact modeling initiatives using deep learning, LLMs, and traditional methods. Prototype, deploy, and monitor hybrid models on large insurance datasets, drive MLOps standards, and communicate results to nontechnical stakeholders to realize business impact.
Top Skills: Deep LearningFederated LearningGlmJupyterLarge Language ModelsMlopsPythonSequence ModelingTime Series ModelingTransformersXgboost
YesterdaySaved
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Remote or Hybrid
Charleston, SC
Easy Apply
135K-165K Annually
Senior level
135K-165K Annually
Senior level
Artificial Intelligence • Insurance • Machine Learning • Software • Analytics
Lead end-to-end development and deployment of predictive and hybrid deep learning/LLM models for insurance use cases. Prototype, validate, and productionize models using modern ML frameworks and MLOps, collaborate with product and engineering, and communicate technical results to stakeholders to drive measurable business impact.
Top Skills: APIsAWSAzureCi/CdDatabricksDockerExperiment TrackingFederated LearningGCPJupyterLightgbmLlmsModel ServingNeural NetworksNumpyPandasPipeline OrchestrationPythonPyTorchRelational DatabasesScikit-LearnSQLTensorFlowTime Series ModelingTransformersXgboost
3 Days AgoSaved
Remote
Charleston, SC
193K-261K Annually
Senior level
193K-261K Annually
Senior level
Artificial Intelligence • Cloud • Consumer Web • Productivity • Software • App development • Data Privacy
Lead product-focused analytics and experimentation to improve core experience and AI initiatives. Build propensity models and segmentation, create automated dashboards and executive reports, run and monitor experiments, and partner cross-functionally to translate analysis into business impact and drive product decisions.
Top Skills: PythonRSQL
Reposted 3 Days AgoSaved
Remote
Charleston, SC
192K-228K Annually
Senior level
192K-228K Annually
Senior level
Healthtech • Social Impact • Software • Telehealth
This role drives data-driven decision-making in product analytics, collaborating with cross-functional teams to generate actionable insights and evaluate new launches to enhance platform growth.
Top Skills: AirflowDbtHexLookerPythonRTableau
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5 Hours AgoSaved
Remote or Hybrid
Charleston, SC
Senior level
Senior level
Software
Design and deploy ML systems for enterprise search, recommendations, retrieval, and AI agents. Build scalable data/ML pipelines, evaluation frameworks, and metrics. Apply statistics, experimentation, and causal inference to guide product decisions. Collaborate cross-functionally, prototype LLM-based capabilities (embeddings, RAG), and mentor junior team members.
Top Skills: Agent Orchestration FrameworksEmbeddingsFoundation ModelsLlmsPythonRetrieval SystemsRetrieval-Augmented Generation (Rag)SQLVector Databases
5 Hours AgoSaved
Remote or Hybrid
Charleston, SC
179K-217K Annually
Senior level
179K-217K Annually
Senior level
Software
Lead design and deployment of ML systems for enterprise search, retrieval, recommendations, and AI agents. Build scalable data/ML pipelines, evaluation frameworks, and KPIs. Apply statistics, causal inference, experimentation, and analysis to guide product strategy. Prototype and productionize LLM-based features, mentor junior staff, and collaborate cross-functionally.
Top Skills: Agent Orchestration FrameworksEmbedding ModelsEmbeddingsFoundation ModelsLlmsPythonRetrieval SystemsRetrieval-Augmented Generation (Rag)SQLVector Databases
Reposted 5 Hours AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Professional Services
Design and implement data-centric cybersecurity solutions: develop ML algorithms and automation for security tools; discover, parse, map, and transform legacy RMF artifacts into OSCAL; migrate and analyze security data; reproduce dashboards/workflows in eGRC; collaborate with Professional Services; produce migration assessments and reports.
Top Skills: AgileAIAws GovcloudD3FendEgrcIaasMachine LearningExcelMicrosoft WordMitre Att&CkOscalRmfSaaSScriptingSdlcSharepointSIEMSoarSsp
Reposted 21 Hours AgoSaved
Remote
Charleston, SC
175K-234K Annually
Senior level
175K-234K Annually
Senior level
Information Technology • Other • Social Media
As a Senior Data Scientist, you'll optimize search relevance, retrieve content, analyze data, and collaborate with teams to enhance product strategies.
Top Skills: Ml ModelsNumpyPandasPythonScikit-LearnSQL
Reposted 21 Hours AgoSaved
Remote
Charleston, SC
220K-250K Annually
Senior level
220K-250K Annually
Senior level
Events • Greentech • Logistics • Software • Transportation • Travel
Lead design and production deployment of ML models focused on pricing, availability, forecasting, and optimization. Build data infrastructure, governance, testing/monitoring, and dashboards. Partner with executives and cross-functional teams, mentor others, and establish scalable data-science practices and experimentation frameworks.
Top Skills: LlmsMachine LearningNlpPythonRSQL
YesterdaySaved
Remote
Charleston, SC
172K-280K Annually
Senior level
172K-280K Annually
Senior level
Artificial Intelligence • Consumer Web • Information Technology • Real Estate • Software • PropTech
Build and deploy end-to-end ML models for renter acquisition, supply optimization, ranking, personalization, and marketplace optimization. Lead technical projects from problem framing through experimentation, launch, monitoring, and iteration. Apply statistical methods, causal inference, and rigorous A/B testing. Partner cross-functionally, mentor other data scientists, and raise modeling and experimentation standards.
Top Skills: AirflowDbtGCPMlopsPythonPyTorchScikit-LearnSQLTensorFlowXgboost
Reposted 2 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Internet of Things
Lead data-driven strategy by partnering with senior executives, design and deliver sophisticated analytical solutions on large-scale data, build trusted cross-functional relationships, and mentor data scientists to raise analytical quality across the organization.
Top Skills: PythonRSQL
Reposted 2 Days AgoSaved
Remote
Charleston, SC
163K-218K Annually
Senior level
163K-218K Annually
Senior level
Internet of Things
Lead data-driven strategy by partnering with senior executives to deliver rigorous analytical solutions. Design and implement sophisticated analyses on large-scale data, build trusted cross-functional relationships, mentor data scientists, and influence long-term product and business decisions.
Top Skills: PythonRSQL
Reposted 8 Days AgoSaved
Remote
Charleston, SC
180K-230K Annually
Senior level
180K-230K Annually
Senior level
Fintech • Information Technology • Software
As a Senior Data Scientist, you'll develop fraud detection models, perform detailed analyses, and work closely with teams to drive product innovation and business outcomes.
Top Skills: Aws Ec2Aws RdsAws RedshiftAws S3PostgresPython 3
Reposted 8 Days AgoSaved
Easy Apply
Remote
Charleston, SC
Easy Apply
160K-200K Annually
Senior level
160K-200K Annually
Senior level
Artificial Intelligence • Enterprise Web • Information Technology • Productivity • Sales • Software • Database
The Senior Data Scientist will analyze data to drive product strategy, optimize performance, and support product launches, collaborating with cross-functional teams.
Top Skills: A/B TestingAmplitudeHeapLookerMachine LearningMixpanelPythonRSASSQL
Reposted 4 Days AgoSaved
In-Office or Remote
Charleston, SC
Senior level
Senior level
Insurance
Senior individual contributor responsible for leading pet/P&C insurance pricing model development (GLMs and ML), owning end-to-end projects, performing EDA and root-cause analysis, communicating results to stakeholders, and mentoring junior team members.
Top Skills: GlmMachine LearningPythonRegression ModelingSQLStatistical Inference
Reposted 4 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Artificial Intelligence • Healthtech • Machine Learning
Develop and tune ML models, productionize and deploy strategies for ML systems, and align cross-functionally to communicate performance metrics.
Top Skills: PysparkPythonPyTorchSQL
Reposted 4 Days AgoSaved
Remote
Charleston, SC
24K-185K Annually
Senior level
24K-185K Annually
Senior level
Cloud • Marketing Tech • Sales • Software
Design, build, and deploy predictive GTM models (LTV, attribution, propensity). Lead experimentation and causal analyses, define KPI measurement frameworks, partner with Data Engineering, and translate statistical insights into actionable recommendations for Sales, Marketing, and Customer Success.
Top Skills: AirflowDatabricksDbtNumpyPandasPythonRScikit-LearnSnowflakeSQL
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