Top Senior Machine Learning Jobs in Charleston, SC

29 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Healthtech • Software • Automation
Lead strategy and build 0->1 AI products that streamline complex healthcare workflows across providers, pharmacies, patients, and pharma partners. Own roadmap, requirements, metrics, and product performance; partner with engineering, data, clinical, and commercial teams to launch and iterate AI-enabled solutions that drive adoption and measurable business and patient outcomes.
Top Skills: AgileAIAi PlatformsAnalyticsExperimentationMachine LearningSaaS
Reposted One Month AgoSaved
Remote
Charleston, SC
150K-215K Annually
Senior level
150K-215K Annually
Senior level
Artificial Intelligence • Machine Learning • Software • Defense
Develop scalable machine learning services for data enrichment, managing the ML lifecycle from model training to deployment, and ensuring performance and reliability standards.
Top Skills: Hugging FaceKubernetesOnnxPyTorchRayTensorFlowTensorrtVllm
One Month AgoSaved
Remote
Charleston, SC
200K-250K Annually
Senior level
200K-250K Annually
Senior level
Machine Learning • Software
Lead backend architecture and implementation for scalable, reliable cloud-hosted web products. Mentor engineers, set standards, integrate agentic AI coding tools, design systems applying ML to large datasets, and balance customer-facing features with technical debt and performance.
Top Skills: Agentic Engineering ToolsAi Coding AgentsCloud ServicesDistributed SystemsJavaMachine LearningRustScalaWeb Applications
One Month AgoSaved
Remote or Hybrid
Charleston, SC
130K-175K Annually
Senior level
130K-175K Annually
Senior level
Other • Software • PropTech
Lead end-to-end product areas that improve build speed, cost accuracy, margin, and throughput. Own strategy, roadmap, and execution for complex financial and operational data products, integrate AI/ML into workflows, write precise requirements, instrument metrics, run experiments, and drive cross-functional outcomes with construction, finance, sales, design, and engineering teams.
Top Skills: AgentsLlmsMachine LearningSQL
One Month AgoSaved
Remote
Charleston, SC
185K-245K Annually
Senior level
185K-245K Annually
Senior level
Healthtech
Lead the Contracts product roadmap for a B2B healthcare SaaS platform, applying deep reimbursement and managed care expertise. Partner with AI engineers to build contract-understanding models, drive adoption, iterate on workflows, create business cases, and coordinate cross-functionally with Legal, Finance, Sales, and SMEs to ensure compliant, revenue-aligned contract execution.
Top Skills: AIB2B SaasDocument ManagementFinancial Modeling SoftwareMachine Learning
One Month AgoSaved
Remote
Charleston, SC
142K-308K Annually
Senior level
142K-308K Annually
Senior level
Healthtech • Insurance
Lead engineering team to define and execute threat detection, platform, analytics, and automation roadmaps. Advance automated, AI-augmented detection and response across SIEM/EDR/NDR/SOAR and cloud environments, partner with Incident Response, and drive measurable risk reduction via metrics and team development.
Top Skills: AICloud Security ToolsEdrIpsMachine LearningNdrOrchestrationSecurity AnalyticsSecurity AutomationSIEMSoar
Reposted One Month AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Logistics • Transportation
Embed with customers to discover needs, design and implement production-grade integrations (APIs, data pipelines, event-driven workflows), deploy and troubleshoot solutions, train IT teams, and drive adoption and measurable business outcomes.
Top Skills: Auth0CRMData PipelinesErpEvent-Driven ArchitectureMachine LearningMessage QueuesNode.jsOauth2PythonRest ApisSAMLSQLTmsTypescriptWebhooks
7 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Artificial Intelligence • Machine Learning • Analytics
Own end-to-end computer vision and machine learning projects for power grid infrastructure, from problem framing and research experimentation through production deployment and monitoring. Develop detection, segmentation, classification, anomaly detection, and foundation-model solutions; build data pipelines, serving systems, experiment tracking, and model versioning. Conduct error analysis, benchmarking, tuning, code reviews, and testing while translating client requirements into reliable production models and communicating technical decisions and limitations.
Top Skills: Ci/CdCnnsDockerDrone MetadataFastapiFoundation ModelsGisGitGithub ActionsLightningMl DevopsModel QuantizationNumpyOpencvPandasPydanticPytestPythonPython Type HintingPyTorchScikit-LearnTransformersVision Language Models
8 Days AgoSaved
Remote
Charleston, SC
211K-249K Annually
Senior level
211K-249K Annually
Senior level
Big Data • Food • Mobile • Payments
Build and improve machine learning systems for ad ranking, relevance, and optimization. Responsibilities include developing active learning and LLM-assisted labeling workflows, owning experimentation and evaluation, and deploying low-latency inference services. The role partners with product, data, and platform teams to improve advertiser performance and user engagement while ensuring production reliability, scalability, latency, and data quality. Candidates will use Python, Go, AWS, distributed systems, and AI-assisted development tools.
Top Skills: AWSAws BedrockChatgptClaudeGithub CopilotGoLangchainLlmsPythonVector Databases
Reposted One Month AgoSaved
Remote
Charleston, SC
144K-299K Annually
Senior level
144K-299K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
Lead the development of deep learning models for email data, optimize models, design evaluation frameworks, integrate products, and mentor junior researchers.
Top Skills: GCPHugging FaceMachine LearningNatural Language ProcessingPythonPyTorchTensorFlow
Reposted One Month AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Automotive
Lead strategy, roadmap, and delivery for Tekmetric's SaaS product for auto repair shops. Own user research, AI/ML product initiatives, cross-functional alignment, go-to-market coordination, and measurement of business outcomes. Train internal teams and iterate on features from concept through launch and optimization.
Top Skills: AmplitudeCloudFullstoryGenerative AiHeapMachine LearningMixpanelPendoSaaS
Reposted One Month AgoSaved
Remote
Charleston, SC
220K-250K Annually
Senior level
220K-250K Annually
Senior level
Events • Greentech • Logistics • Software • Transportation • Travel
Lead design and production deployment of ML models focused on pricing, availability, forecasting, and optimization. Build data infrastructure, governance, testing/monitoring, and dashboards. Partner with executives and cross-functional teams, mentor others, and establish scalable data-science practices and experimentation frameworks.
Top Skills: LlmsMachine LearningNlpPythonRSQL
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One Month AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Professional Services • Software
Lead and grow a team of Conversation Designers to build and scale conversational AI experiences. Partner with Product, Engineering, Analytics, and ML teams to drive strategy, tooling, evaluation, and quality practices. Recruit and remove roadblocks, own strategic initiatives, and remain hands-on in designing, testing, and improving AI-driven conversational products.
Top Skills: A/B TestingAi ToolsEvaluation FrameworksLlmsMachine Learning
One Month AgoSaved
Remote
Charleston, SC
Senior level
Senior level
AdTech
Lead full sales cycle to drive CTV performance advertising growth in North America: prospect, close, launch and scale CTV budgets, manage key advertiser relationships, collaborate cross-functionally, represent Jampp at events (20% travel), and provide local feedback to improve global initiatives.
Top Skills: AttributionConnected Tv (Ctv)Creative OptimizationMachine LearningMobile AdvertisingPerformance MarketingProgrammatic Advertising
One Month AgoSaved
Remote
Charleston, SC
Senior level
Senior level
eCommerce
Lead development and deployment of cutting-edge ML models for pricing, design and analyze experiments, collaborate with product and engineering, present findings to stakeholders, and lead technical projects to influence team output and business metrics.
Top Skills: AIMachine LearningMachine Learning AlgorithmsPython
One Month AgoSaved
In-Office or Remote
Charleston, SC
38K-136K Annually
Senior level
38K-136K Annually
Senior level
Agency • Information Technology
Senior Business Systems Analyst responsible for capturing functional requirements for agent-facing servicing applications, defining integrations/APIs with core banking systems, translating needs into user stories and acceptance criteria, supporting testing and releases, analyzing workflows to improve agent productivity, and identifying AI/ML opportunities for fraud detection and automation.
Top Skills: AIAPIsCore Banking SystemsMachine Learning
Reposted One Month AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Artificial Intelligence • Software
Lead development and optimization of web scraping pipelines to extract, clean, and store large-scale web data. Handle dynamic content, pagination, distributed scraping, database design with NoSQL, deploy jobs to cloud, and monitor systems for reliability and data quality. Support ML-based data cleaning and categorization.
Top Skills: Asynchronous ProgrammingAWSAzureBeautifulsoupCassandraCSSDistributed ScrapingDomGCPHTMLJavaScriptMachine LearningMongoDBMultithreadingPythonScrapySelenium
One Month AgoSaved
Remote
Charleston, SC
165K-185K Annually
Senior level
165K-185K Annually
Senior level
Artificial Intelligence • Insurance • Software • Automation
Lead end-to-end enterprise customer engagements and onboarding for large insurance clients, run program timelines and executive reporting, design and deploy AI agents and internal tooling, own the CE operations roadmap and knowledge base, drive cross-functional resolution of technical/operational issues, and continuously improve efficiency and quality across the Client Engagement team.
Top Skills: AIAi AgentsAPIsJSONMachine Learning
Reposted One Month AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Information Technology • Software • Cybersecurity • Automation
Lead global marketing strategy and GTM to scale Aisle into a market leader. Own brand, PR, product positioning, full-funnel demand generation, ABM, marketing tech stack, RevOps, attribution, budget/agency management, and grow a multidisciplinary marketing team aligned to revenue targets.
Top Skills: AbmAIAttribution/Analytics/DashboardsCRMIntent Data PlatformsMachine LearningMarketing AutomationRevops
9 Days AgoSaved
In-Office or Remote
Charleston, SC
110K-120K Annually
Senior level
110K-120K Annually
Senior level
Healthtech • Other • Professional Services • Social Impact
Operate Dataiku and Databricks environments supporting production analytics and machine-learning pipelines. Responsibilities include promoting data-science projects to production, packaging Python environments, configuring monitoring and alerting, triaging pipeline failures, administering platform users and policies, coordinating with data owners, tracking operational demand, writing runbooks, and supporting automation design reviews. The role requires strong operational judgment, Python and AWS experience, clear incident communication, and effective support for data scientists transitioning projects from development to production.
Top Skills: Amazon RedshiftAmazon S3Amazon SagemakerAWSAws IamDatabricksDataikuDominoMicrosoft FabricPythonUvVenv
Reposted One Month AgoSaved
Remote
Charleston, SC
161K-222K Annually
Senior level
161K-222K Annually
Senior level
Healthtech • HR Tech
Lead product strategy and execution for data and AI platforms, driving GenAI/LLM initiatives, cross-functional collaboration, responsible AI governance, experimentation (A/B testing), measurement of model impact, and mentoring product teams to embed scalable ML capabilities into clinical and member experiences.
Top Skills: Advanced AnalyticsAgentic AiAi InfrastructureCloudData EngineeringData ScienceDeep LearningEnterprise SaasGenerative AiLarge Language Models (Llms)Machine LearningOnline Controlled A/B Testing
Reposted One Month AgoSaved
Remote
Charleston, SC
171K-201K Annually
Senior level
171K-201K Annually
Senior level
Fintech • Analytics • Financial Services
Design, build, and scale backend systems and APIs for high-transaction consumer products. Collaborate with product, credit, compliance, support, and analytics teams. Contribute to code reviews, technical planning, security, and operational excellence. Mentor peers and promote engineering best practices.
Top Skills: .Net (C#)APIsAugmentCursorFactoryMachine Learning
Reposted One Month AgoSaved
In-Office or Remote
Charleston, SC
180K-220K Annually
Senior level
180K-220K Annually
Senior level
Marketing Tech
Lead the development and implementation of machine learning solutions, managing a team to drive strategic decisions and innovative business outcomes.
Top Skills: Artificial IntelligenceMachine LearningStatistical Techniques
Reposted One Month AgoSaved
Remote
Charleston, SC
128K-267K Annually
Senior level
128K-267K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
Design, implement, and scale ML-based solutions for search and advertising; define data collection, evaluation, and production serving strategies; analyze data to inform development; communicate cross-functionally; produce technical reports; and stay current with advances in LLMs, vision models, and generative AI.
Top Skills: Deep LearningGenerative AiJavaLarge Language ModelsMachine LearningNatural Language ProcessingPythonVision Models
9 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Edtech • Software
Industry Expert who reviews and defends advanced AI/ML and systems engineering projects, chairs architecture and executive review panels, hosts occasional technical sessions, and sets standards for instructors. The role requires production-scale engineering experience, live architecture critique, a public technical footprint, strong English, and expertise in agentic systems, LLM evaluation, model serving, cloud infrastructure, distributed systems, observability, RAG, and enterprise deployments.
Top Skills: A/B TestingAdkAPIsAWSCi/CdCrewaiDistributed SystemsKubernetesLangchainLanggraphLlm Evaluation HarnessesLlm ObservabilityLlm-As-JudgeLlmsLoraMcpModel ServingPeftRagSftTerraform
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