Top Senior Machine Learning Jobs in Charleston, SC

YesterdaySaved
Remote or Hybrid
Charleston, SC
160K-240K Annually
Senior level
160K-240K Annually
Senior level
Artificial Intelligence
Design, train, and deploy scalable ML models (generative, classification, regression). Define feature roadmaps, collaborate with engineering to implement code and APIs, adapt ML methods for distributed/GPU environments, and create evaluation/annotation programs for fine-tuning and performance measurement.
Top Skills: Apache BeamSparkApi DevelopmentDistributed SystemsGpuPythonPyTorchTensorFlow
YesterdaySaved
Remote
Charleston, SC
115K-145K Annually
Senior level
115K-145K Annually
Senior level
Other
Design, build, and deploy scalable AI/ML systems and pipelines. Develop reusable Python packages, RAG/LLM integrations, agentic workflows, evaluation/monitoring frameworks, optimized data queries, and MLOps practices while collaborating across cross-functional teams.
Top Skills: Agentic ArchitecturesAutogenAWSAzureCi/CdContainerizationDatabricksDistributed Computing FrameworksGCPHugging FaceLangchainLanggraphLlamaindexLlm IntegrationMlopsNonrelational DatabasesPythonRelational DatabasesRetrieval-Augmented Generation (Rag)
YesterdaySaved
In-Office or Remote
Charleston, SC
Senior level
Senior level
Information Technology
Design, train, evaluate, and deploy predictive transportation and delivery ML models (primarily XGBoost). Perform EDA, feature engineering, experiment design, and statistical evaluation. Build production ML pipelines and MLOps practices on Google Vertex AI. Collaborate with data engineering and supply chain stakeholders to translate operational needs into scalable solutions.
Top Skills: AWSAzureGCPGoogle Vertex AiPythonSQLXgboost
YesterdaySaved
Remote
Charleston, SC
140K-180K Annually
Senior level
140K-180K Annually
Senior level
Software • Analytics • Cybersecurity
Design, build, and own production ML and LLM-powered product features (chat, RAG, semantic search, data extraction). Write maintainable code and docs, debug issues, collaborate with product and design, follow Agile practices, and stay current on AI/ML methods.
Top Skills: AWSAzureDockerHugging FaceJavaJavaScriptKerasKnowledge DistillationKubernetesLarge Language Models (Llms)MxnetNode.jsPostgresPrompt EngineeringPythonPyTorchRetrieval-Augmented Generation (Rag)Scikit-LearnSemantic SearchTensorFlowTypescript
YesterdaySaved
Remote
Charleston, SC
Senior level
Senior level
Gaming • Machine Learning • News + Entertainment • Design • Conversational AI • Generative AI
Own and improve recommendation and search systems across feed, discovery, and search. Build retrieval and ranking (candidate generation, embeddings, two-tower models), run experiments, create user/content/session representations, and ship production ML systems with monitoring to improve retention, engagement, and content distribution.
Top Skills: A/B ExperimentationCandidate GenerationContextual BanditsData PipelinesEmbedding-Based RetrievalEmbeddingsLlm-Powered RankingMultimodal Content UnderstandingOnline ServingProduction Ml SystemsRanking SystemsRecommendation SystemsReinforcement LearningSearchSemantic SearchTwo-Tower Models
24 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Artificial Intelligence • Marketing Tech • Software
The Senior Product Manager will set product direction, own the development lifecycle, collaborate with teams, and ensure high-quality outputs. This role requires strong opinions on product quality and customer insights.
Top Skills: AIMachine LearningProduct Management
24 Days AgoSaved
Remote or Hybrid
Charleston, SC
Senior level
Senior level
Artificial Intelligence • Natural Language Processing • Software
Lead the strategy and execution of product marketing efforts, create compelling narratives for products, and collaborate with cross-functional teams to enhance user adoption and achieve growth objectives.
Top Skills: Machine LearningNlpSaaS
YesterdaySaved
Remote
Charleston, SC
136K-167K Annually
Senior level
136K-167K Annually
Senior level
Fashion
Design, develop, and maintain scalable ML and AI platform infrastructure for model training, deployment, feature engineering, candidate generation, agent deployment, and observability. Collaborate with data scientists and engineers, support platform operations, drive improvements, codify best practices, and influence platform investments to enable production ML systems at scale.
Top Skills: AnyscaleAWSFastapiGenerative AiGoKafkaLanggraphLangsmithPostgresPythonRayRedis
Reposted YesterdaySaved
Remote
Charleston, SC
128K-165K Annually
Senior level
128K-165K Annually
Senior level
Financial Services
The Senior Analyst in Predictive Analytics and Machine Learning develops and maintains statistical models to support business decisions, monitors model performance, and collaborates with stakeholders across the company.
Top Skills: PythonRSASSQL
24 Days AgoSaved
In-Office or Remote
Charleston, SC
250K-290K Annually
Senior level
250K-290K Annually
Senior level
Hardware • Security • Software • Cybersecurity
The Director of Computer Vision will lead technical vision, research, and execution in developing scalable AI-driven computer vision solutions, managing teams, and enhancing performance metrics.
Top Skills: Computer VisionMachine LearningMlops
Reposted 24 Days AgoSaved
In-Office or Remote
Charleston, SC
Senior level
Senior level
Logistics • Software
Lead the Decision Science function, designing ML models, overseeing experimentation frameworks, and ensuring model adoption across the company, driving operational and commercial improvements.
Top Skills: BigQueryDbtMachine Learning
Reposted 24 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Artificial Intelligence • Fintech • Software • Financial Services
The role involves building, deploying, and maintaining ML infrastructure, optimizing systems, and ensuring production reliability while collaborating with data scientists and product teams.
Top Skills: AWSFlinkMachine LearningPythonScalaSpark
New

Cut your apply time in half.

Use ourAI Assistantto automatically fill your job applications.

Use For Free
Application Tracker Preview
Reposted 24 Days AgoSaved
Remote
Charleston, SC
179K-186K Annually
Senior level
179K-186K Annually
Senior level
Artificial Intelligence • Software
Lead pre-sales technical engagements for Conversational and Generative AI solutions, collaborate across teams, and design value-driven demos for enterprise customers.
Top Skills: AIAPIsAsrCloud ServicesConversational AiGenerative AiLlmsMachine LearningNluSpeech-To-Text EnginesTts
Reposted 24 Days AgoSaved
Remote
Charleston, SC
170K-200K Annually
Senior level
170K-200K Annually
Senior level
Healthtech • Pharmaceutical • Hospitality
Manage the development and implementation of Evio Compass, an analytic product identifying patient risks, while guiding cross-functional teams to drive customer success and enhance ML/AI product features.
Top Skills: AIAnalyticsData ScienceDigital Health ToolsMachine Learning
Reposted 24 Days AgoSaved
Remote
Charleston, SC
86K-145K Annually
Senior level
86K-145K Annually
Senior level
Fintech • Payments • Financial Services
The role involves researching, developing, and implementing AI solutions, optimizing models, integrating AI into workflows, and collaborating with teams to enhance business efficiency.
Top Skills: APIsArtificial IntelligenceData PipelinesMachine LearningMicroservices
2 Days AgoSaved
Remote
Charleston, SC
175K-220K Annually
Senior level
175K-220K Annually
Senior level
Software
Design, build, and ship AI-powered observability features using LLMs and agentic workflows. Rapidly prototype, iterate with real users, integrate AI into alerting, runbooks, and developer workflows, and ensure solutions are scalable, maintainable, and production-ready while collaborating cross-functionally.
Top Skills: AWSAzureGCPGenerative AiLlmsObservability ToolsPrompt Engineering
Reposted 2 Days AgoSaved
Remote
Charleston, SC
221K-292K Annually
Senior level
221K-292K Annually
Senior level
Financial Services
Lead design, deployment, and monitoring of predictive models for credit risk, collections, and operations. Drive adoption of modern ML and MLOps, mentor data scientists, define strategic roadmap, advise senior leadership, and ensure model governance and regulatory compliance.
Top Skills: AWSAzureGCPKubeflowMlflowPythonRSASSQL
Reposted 2 Days AgoSaved
Remote
Charleston, SC
203K-245K Annually
Senior level
203K-245K Annually
Senior level
HR Tech • Software
The Machine Learning Engineer will execute the full ML lifecycle, collaborating on model implementation and improving customer experiences through data-driven insights.
Top Skills: AirflowSparkBeamJavaKerasPythonPyTorchScalaSQLTensorFlowVertexai
Reposted 2 Days AgoSaved
Remote
Charleston, SC
157K-294K Annually
Senior level
157K-294K Annually
Senior level
Artificial Intelligence • Software
Lead the end-to-end machine learning lifecycle for AI products, managing data pipelines and model development to optimize performance and accuracy in production.
Top Skills: AWSGCPJaxNumpyPandasPythonPyTorchTensorFlow
Reposted 2 Days AgoSaved
Remote or Hybrid
Charleston, SC
153K-198K Annually
Senior level
153K-198K Annually
Senior level
AdTech • Digital Media • eCommerce • Marketing Tech • Mobile • Software
The Senior Machine Learning Engineer will manage the full ML lifecycle, collaborating with teams to develop scalable systems that improve product decisions and empower monetization strategies.
Top Skills: AirflowAWSDbtPythonPyTorchRedisScikit-LearnSparkSQLTensorFlow
Reposted 2 Days AgoSaved
Remote
Charleston, SC
190K-240K Annually
Senior level
190K-240K Annually
Senior level
Healthtech
The Staff Machine Learning Engineer will lead ML initiatives, develop AI systems, optimize pipelines, and mentor team members to automate healthcare processes.
Top Skills: AirflowBedrockHugging FaceMlflowPythonPyTorchSagemakerScikit-LearnVertex AiW&B
Reposted 2 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Artificial Intelligence • Automotive • Transportation
Lead research on humanistic AI for autonomous systems. Collaborate with teams, design experiments, and publish findings in top-tier publications.
Top Skills: C++Python
Reposted 2 Days AgoSaved
Remote
Charleston, SC
185K-271K Annually
Senior level
185K-271K Annually
Senior level
Productivity • Software • Conversational AI
Lead the design and operation of Twilio's ML and data platform, architecting cloud-native pipelines and implementing MLOps best practices while mentoring engineers and collaborating across teams.
Top Skills: AWSC++EksFlinkGoJavaKafkaKinesisKubeflowKubernetesMlflowNoSQLPythonSagemakerScalaSparkSQLTerraformVertex Ai
Reposted 25 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Artificial Intelligence • Big Data • Big Data Analytics
Seeking a Senior Researcher to evaluate and optimize video datasets for training generative video models, ensuring data quality and effectiveness through analysis and characterization.
Top Skills: Computer ScienceMachine LearningStatistics
Reposted 25 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Software • Analytics • Consulting • Financial Services
Lead technical solution development for military and Federal civilian health capture and proposal efforts, ensuring technical compliance and producing quality architecture designs.
Top Skills: AgileAWSAzureData GovernanceData PipelinesDevOpsETLFhirGCPHl7Machine LearningSafe
All Filters
JobType
New Jobs
Job Category
Experience
Industry
Company Name
Company Size

Sign up now Access later

Create Free Account