Top Senior IT Jobs in Charleston, SC

Lead and coordinate IT and security audits across cloud infrastructure, application security, IAM, vendor risk, and blockchain products; shape audit roadmap; produce executive- and Board-level reports; drive remediation and validate corrective actions; partner with technology leaders and mentor audit staff.

Lead end-to-end IT and security audits across cloud infrastructure, application security, IAM, vendor risk, and blockchain products. Plan and execute fieldwork, produce evidence-based reports for senior leaders and the Audit Committee, mentor junior auditors, validate remediation, and partner with Engineering and Security to improve controls while maintaining audit independence.

Provide Tier 2 technical support and own escalations across devices, apps, and cloud platforms. Administer enterprise SaaS (Google Workspace, Atlassian, Okta, Jamf, Slack), perform root cause analysis, build SOPs/KB content, partner with cross-functional teams, and use automation and generative AI responsibly to reduce tickets and improve service.

The Senior Solutions Architect II leads the design and implementation of large-scale solutions, drives innovation, and mentors team members. They also collaborate on pre-sales with Sales teams and serve as technical escalation points for complex issues.

Lead Coinbase's global IT and security audit program, delivering complex cross-functional audits across cloud, infrastructure, cybersecurity, IAM, data protection, and third-party risk. Manage and develop a global audit team, partner with first- and second-line stakeholders to drive integrated assurance, and report executive-level findings to senior leadership and the Audit Committee. Modernize audit execution through data analytics, automation, and generative AI to enable continuous monitoring and automated evidence retrieval.

Lead architecture and delivery of IT automations and integrations across platforms (n8n, Airflow, Temporal, Jira). Act as technical DRI for complex automation projects, partner with Security and IAM, build reusable frameworks and documentation, establish engineering standards and code review practices, and mentor peers.

Lead end-to-end execution of enterprise IT systems initiatives, unblock technical bottlenecks, integrate and consolidate tooling, drive user adoption and training, build dashboards and post-mortems, and serve as strategic liaison between IT domains and business stakeholders to deliver cross-functional IT programs.

Own IT-specific Sarbanes-Oxley (SOX) compliance for ITGCs and ITACs. Assess SOX readiness for systems and process changes, maintain control documentation, coordinate walkthroughs and remediation, liaise with internal/external auditors, review SOC reports, oversee testing programs, and identify automation and AI opportunities to strengthen controls and reporting.

Support risk assessment, audit planning, and oversight of audit management and staff. Provide advisory services and ensure compliance with standards.

The Lead Technical Support Engineer resolves complex technical issues, provides mentorship, collaborates with teams, and improves support systems.

The role involves developing, testing, and maintaining computer programs, supporting complex analyses, managing development efforts, and ensuring alignment with organizational methodologies.

The Technical Project Manager oversees IT project planning, execution, and delivery within the government sector, ensuring stakeholder coordination and compliance with regulations.

The Test Manager designs and executes comprehensive testing processes, manages testing events, oversees engineering activities, ensures effective schedule and resource allocation, and maintains quality assurance for large-scale systems integration.

Manage IT vendor and procurement operations including negotiating SaaS, hardware, and services contracts; drive renewals; onboard new vendors ensuring compliance; partner with Legal, Finance, and InfoSec; maintain procurement documentation; support technology asset procurement and improve procurement policies and processes.

Lead and execute remote technical implementations for dental practices from signing through go-live. Configure PMS integrations, set up remote access and network configurations, manage AWS-hosted Windows VMs/ETL, handle support volume, liaise with MSPs, and improve onboarding processes and automation while partnering with cross-functional teams.

The Senior IT Infrastructure Engineer will enhance automation and integration efforts while managing cloud services, CI/CD pipelines, and Kubernetes operations.

Design, build, and maintain automation and CI/CD for secure cloud and software delivery. Develop scripts, pipelines, and IaC; support vulnerability remediation, troubleshooting, documentation, and mentor junior engineers to ensure compliant, repeatable deployments.

Support and mature enterprise FinOps practices for cloud and AI environments. Monitor and report spend, enforce tagging and cost allocation, track AI-specific metrics (tokens, GPU hours), identify optimization opportunities, maintain FinOps tooling and dashboards, and provide financial inputs for governance and PMO reviews.

Lead end-to-end deployments of Medicaid MMIS/MES and related Health IT systems. Plan, schedule, and manage go-lives, deployment readiness, integrations, and installation of network equipment. Maintain implementation plans, coordinate cross-functional teams and stakeholders, ensure CMS/state compliance, and provide status reporting. Remote role with 25–50% travel.

Lead complex, FAR-compliant sourcing and procurement initiatives, manage end-to-end RFPs/RFQs, negotiate supplier agreements, ensure regulatory compliance and risk mitigation, engage suppliers, and improve processes while mentoring the procurement team.

Serve as embedded IT risk partner for engineering and technology teams, owning IT SOX readiness, control design, testing coordination, remediation oversight and auditor liaison. Assess ITGCs and application controls across cloud, DevOps, CI/CD, IAM and Kubernetes environments. Drive control automation, continuous monitoring, evidence quality, and translate technical risks into practical guidance for engineers, Finance, and external auditors.

Lead Manhattan Active WM solution design and multi-site rollout, migrate legacy WMS/TMS/WES/WCS, define processes and standards, validate warehouse hardware and automation, manage integrations, testing, cutover, go-live stabilization, documentation, and mentor internal teams.

Perform hands-on application, API, and AWS cloud penetration testing and vulnerability assessments for CMM systems to support ATO packages. Validate NIST 800-53 controls, document findings and exploitation steps, produce SARs, and work with DevSecOps and engineering teams to remediate and retest issues. Support RMF Step 3, CI/CD security, container and cloud security testing, threat modeling, and security integration into Agile sprints.

Lead and execute demand generation strategy for internal IT buyers: build GTM playbook, run integrated inbound/outbound campaigns, own pipeline metrics and reporting, partner with Sales/Rev Ops/Marketing to drive pipeline and revenue.

Lead IT SOX Compliance Coordinator supports IT SOX program: perform SOX controls, manage audits and walkthroughs, maintain control inventories and SOPs, remediate deficiencies, coordinate with auditors and application owners, and recommend process improvements to ensure IT control compliance.