Top Senior Machine Learning Jobs in Charleston, SC

25 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Angel or VC Firm • Automotive • Transportation
Lead Data Science initiatives, build AI/ML solutions, and mentor teams in a collaborative environment, driving innovation in a leading construction equipment venture.
Top Skills: AIAWSAzureData BricksData EngineeringDbtDockerFivetranGCPKubernetesMachine LearningSnowflakeTerraform
2 Days AgoSaved
Remote
Charleston, SC
300K-375K Annually
Senior level
300K-375K Annually
Senior level
AdTech • Marketing Tech
Lead design, build, and operation of end-to-end production ML systems for ranking, rewards, ROAS/LTV prediction, personalization, and offer optimization. Own feature pipelines, training, inference, experimentation, monitoring, retraining, and MLOps. Partner with Data Engineering, BI, Product, and Engineering to connect ML to business outcomes, mentor engineers, and drive an AI-first engineering culture.
Top Skills: Apache IcebergEmbeddingsExperimentation/A-B Testing FrameworksFeature PlatformsKafkaMlopsModel ServingStreaming/Near-Real-Time Decisioning
2 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Artificial Intelligence • Edtech • HR Tech • Software
Design, build, deploy, and operate production-grade AI/ML and LLM systems (including RAG and agentic pipelines). Integrate AI capabilities with product workflows, run evaluation and monitoring, optimize model and system performance, and apply strong engineering practices (testing, CI/CD, versioning).
Top Skills: Ci/CdCloudLlmsPythonRag
2 Days AgoSaved
Remote
Charleston, SC
165K-190K Annually
Senior level
165K-190K Annually
Senior level
Big Data
Design and implement production ML features, close behavior gaps with common frameworks, investigate divergences, improve performance and stability, and document designs and tests for geospatial and large-scale ML workflows.
Top Skills: C++JavaScalaScikit-LearnSpark MlXgboost
2 Days AgoSaved
In-Office or Remote
Charleston, SC
144K-230K Annually
Senior level
144K-230K Annually
Senior level
Healthtech
Lead design, development, and delivery of ML, DL, and Generative AI systems for production. Apply prescriptive analytics, optimization, recommendation, and reinforcement learning. Build and evaluate models, run experiments, develop prototypes, benchmark methods, and collaborate with business partners to translate data into actionable recommendations and influence strategy.
Top Skills: Artificial Intelligence (Ai)Data VisualizationDeep LearningGenerative AiMachine Learning (Ml)OptimizationPredictive AlgorithmsPrescriptive AnalyticsRecommendation SystemsReinforcement LearningStatistical Modeling
2 Days AgoSaved
Remote or Hybrid
Charleston, SC
Senior level
Senior level
Information Technology • Database • Consulting
Design, build, and operate end-to-end ML pipelines including data ingestion, feature engineering, training, deployment, and monitoring. Deploy and scale models on AWS or GCP, implement CI/CD, containerization, orchestration, model lifecycle management, observability, and mentor junior engineers to productionize personalization, recommendation, and NLP solutions.
Top Skills: Apache AirflowAws EksAws LambdaAws SagemakerAws Step FunctionsCloudFormationDockerFeastGcp Cloud FunctionsGcp Vertex AiGithub ActionsGkeGrafanaJenkinsKfservingKubernetesMlflowPrometheusPythonPyTorchRay ServeScikit-LearnSeldonSparkSQLTensorFlowTerraform
2 Days AgoSaved
In-Office or Remote
Charleston, SC
Senior level
Senior level
Agency • Information Technology
Design, develop, and deploy end-to-end machine learning models using statistical and ML algorithms. Prepare and enrich data, implement scalable PySpark/Databricks solutions, and collaborate with product and engineering to create personalized customer experiences and actionable insights.
Top Skills: DatabricksJupyter NotebooksNumpyPandasPysparkPythonPyTorchScikit-LearnSparkTensorFlow
2 Days AgoSaved
Remote
Charleston, SC
48K-170K Annually
Senior level
48K-170K Annually
Senior level
Agency • Information Technology
Design, develop, fine-tune, and deploy generative AI models (GANs, VAEs, transformers). Collaborate with cross-functional teams, troubleshoot model issues, document work, and communicate technical concepts to non-technical stakeholders while staying current on research.
Top Skills: BertDeep LearningGansGptNlpPrompt EngineeringPythonPyTorchTensorFlowTransformer ModelsVaes
2 Days AgoSaved
In-Office or Remote
Charleston, SC
42K-148K Annually
Senior level
42K-148K Annually
Senior level
Agency • Information Technology
Design, develop, fine-tune, and deploy generative AI models using deep learning and transformer architectures. Collaborate cross-functionally, troubleshoot model issues, optimize performance, document work, and communicate technical concepts to non-technical stakeholders.
Top Skills: Bert)Deep LearningGansNlpPrompt EngineeringPythonPyTorchTensorFlowTransformers (GptVaes
2 Days AgoSaved
In-Office or Remote
Charleston, SC
62K-217K Annually
Senior level
62K-217K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production Generative AI applications: orchestrate multi-agent workflows, implement advanced RAG with vector DBs, integrate and fine-tune LLMs, develop scalable FastAPI/async backends, containerize with Docker, and optimize GenAI systems for latency, cost, and reliability.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLocal LlmsMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchRagTensorFlowVector DatabasesVector Search
2 Days AgoSaved
Remote
Charleston, SC
47K-166K Annually
Senior level
47K-166K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production-grade ML and AI systems end-to-end, combining classical ML, deep learning, and LLM/agentic integrations. Implement MLOps, monitoring, CI/CD, model serving, vector search/RAG pipelines, and scalable APIs; mentor engineers and drive engineering best practices.
Top Skills: AnthropicAutogenChromaCi/CdCrewaiDockerFastapiFlaskGeminiHadoopKubernetesLangchainLanggraphLlamaindexLoraMilvusMlflowNumpyOpenaiPandasPineconePrompt EngineeringPythonPyTorchQloraRagSagemakerScikit-LearnSparkSQLTensorFlowVector SearchVertex AiWeaviate
2 Days AgoSaved
In-Office or Remote
Charleston, SC
79K-276K Annually
Senior level
79K-276K Annually
Senior level
Agency • Information Technology
Build and scale production Generative AI applications: design multi-agent systems and LangGraph workflows, implement advanced RAG with LlamaIndex and vector DBs, integrate and fine-tune various LLMs, and deploy containerized FastAPI services with monitoring, CI/CD, and performance/cost optimizations.
Top Skills: Api SecurityAsync PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiGenai OptimizationHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm QuantizationLocal Llm DeploymentModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector SearchWorkflow Design
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2 Days AgoSaved
In-Office or Remote
Charleston, SC
48K-170K Annually
Senior level
48K-170K Annually
Senior level
Agency • Information Technology
Lead architecture, design, and delivery of Generative AI and ML solutions. Build scalable ML pipelines, LLM and RAG-based applications, vector DB integrations, and agent workflows. Drive MLOps, CI/CD, observability, security, and enterprise model orchestration. Provide technical leadership, mentor engineers, run Agile development, and shape AI strategy through POCs and platform innovation.
Top Skills: Agent-Based Ai WorkflowsAi ApisAi ObservabilityCi/CdLlmsMlopsModel OrchestrationRagVector Databases
2 Days AgoSaved
In-Office or Remote
Charleston, SC
62K-217K Annually
Senior level
62K-217K Annually
Senior level
Agency • Information Technology
Design, build, and scale production Generative AI applications: multi-agent systems, advanced RAG pipelines, LLM integration and fine-tuning, scalable FastAPI backends, vector search, monitoring, and Dockerized deployments.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLocal LlmsLocal Model QuantizationModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
2 Days AgoSaved
In-Office or Remote
Charleston, SC
53K-188K Annually
Senior level
53K-188K Annually
Senior level
Agency • Information Technology
Design, build, and productionize generative AI solutions: advanced Python development, LLM prompt engineering and fine-tuning, agent frameworks, RAG pipelines with vector DBs, API and cloud deployment, MLOps/LLMOps, model evaluation and Responsible AI practices, and translate business needs into scalable AI applications.
Top Skills: AdkAWSAzureETLFaissFastapiFine-TuningGCPLangchainLanggraphLlmsMicroservicesMlopsPineconePrompt EngineeringPythonRestRetrieval-Augmented Generation (Rag)Streaming
2 Days AgoSaved
In-Office or Remote
Charleston, SC
56K-196K Annually
Senior level
56K-196K Annually
Senior level
Agency • Information Technology
Build and scale production-ready generative AI applications: design multi-agent workflows, implement advanced RAG with vector DBs, integrate/swap LLMs, fine-tune models, and deploy scalable FastAPI/Docker services with monitoring and optimization for latency, cost, and reliability.
Top Skills: Async PythonCi/CdClaudeDockerFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm Quantization/HostingModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector Databases
2 Days AgoSaved
In-Office or Remote
Charleston, SC
62K-217K Annually
Senior level
62K-217K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production-grade generative AI applications: orchestrate multi-agent systems, implement advanced RAG with vector DBs, fine-tune and host LLMs, optimize GenAI workflows, and deliver scalable FastAPI-based backend services with Docker and monitoring.
Top Skills: Api SecurityAsynchronous ProgrammingCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm QuantizationLocal LlmsModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
2 Days AgoSaved
In-Office or Remote
Charleston, SC
62K-217K Annually
Senior level
62K-217K Annually
Senior level
Agency • Information Technology
Design, build, and scale production Generative AI systems: multi-agent orchestration, advanced RAG with vector databases, LLM integration and fine-tuning, scalable FastAPI backends, Dockerized deployment, monitoring, and GenAI optimization for latency, cost, and reliability.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLocal Llm DeploymentMulti-Agent Systems (Mas)OpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
2 Days AgoSaved
In-Office or Remote
Charleston, SC
79K-276K Annually
Senior level
79K-276K Annually
Senior level
Agency • Information Technology
Design, build, and scale production Generative AI applications including multi-agent systems, advanced RAG pipelines, and local/frontier LLM deployments. Implement high-performance backends with FastAPI and async Python, fine-tune and quantize models, integrate vector databases and retrieval systems, and deploy/monitor containerized AI services for reliability, latency, and cost optimization.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLocal Llm Quantization/HostingModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchRagTensorFlowVector Databases
2 Days AgoSaved
In-Office or Remote
Charleston, SC
44K-154K Annually
Senior level
44K-154K Annually
Senior level
Agency • Information Technology
Design, develop, and deploy machine learning and deep learning models; build end-to-end ML pipelines including preprocessing, training, evaluation, and deployment; perform feature engineering on large datasets; deploy and monitor models on cloud platforms; collaborate with cross-functional teams to integrate AI solutions and retrain models as needed.
Top Skills: AWSAzureCi/CdComputer VisionDockerGCPHadoopKubernetesLlmsNlpPythonPyTorchScikit-LearnSparkSQLTensorFlow
2 Days AgoSaved
In-Office or Remote
Charleston, SC
56K-196K Annually
Senior level
56K-196K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production-ready generative AI applications: architect multi-agent workflows, implement advanced RAG with vector DBs, integrate/swap LLMs, fine-tune models, and deliver scalable FastAPI-based services with monitoring, CI/CD, and containerized deployment.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
2 Days AgoSaved
In-Office or Remote
Charleston, SC
53K-188K Annually
Senior level
53K-188K Annually
Senior level
Agency • Information Technology
Build, optimize, and scale production Generative AI applications. Design multi-agent systems and LangGraph workflows, implement advanced RAG with LlamaIndex and vector DBs, fine-tune and deploy LLMs, and create high-performance FastAPI async backends. Improve latency, cost, and reliability, containerize services with Docker, and manage monitoring, API security, and CI/CD for ML deployments.
Top Skills: Api SecurityAsync PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm Quantization/HostingLocal Model DeploymentModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
2 Days AgoSaved
In-Office or Remote
Charleston, SC
50K-177K Annually
Senior level
50K-177K Annually
Senior level
Agency • Information Technology
Operate and monitor ML/AI models and agentic systems in production. Build AI observability, logging, tracing, and evaluation pipelines. Monitor LLM outputs, detect drift and model degradation, and maintain data/feature pipelines. Develop CI/CD, model versioning, experiment tracking, and automate alerts and incident remediation while collaborating with data scientists and platform teams.
2 Days AgoSaved
In-Office or Remote
Charleston, SC
71K-249K Annually
Senior level
71K-249K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production generative AI applications: orchestrate multi-agent workflows, implement advanced RAG with vector databases, integrate/benchmark LLMs, fine-tune models, and deploy scalable FastAPI-based services with monitoring, CI/CD, and Dockerized production pipelines.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm QuantizationLocal Llm DeploymentModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchRagTensorFlowVector DatabasesVector Search
2 Days AgoSaved
In-Office or Remote
Charleston, SC
53K-188K Annually
Senior level
53K-188K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production-grade generative AI systems: multi-agent orchestration, advanced RAG with vector databases, integrate/swap LLMs, fine-tune models, optimize prompts and latency, and containerize services with monitoring and CI/CD.
Top Skills: Api SecurityAsynchronous ProgrammingCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLocal LlmsModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchQuantizationRagTensorFlowVector Databases
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