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Top Data Science Jobs in Charleston, SC
Fintech
Build and deploy machine learning models for credit and fraud risk, analyze portfolio performance, monitor models in production, develop risk strategies, collaborate with engineering and cross-functional partners, and conduct high-impact ad-hoc analyses to inform business decisions.
Top Skills:
MlopsPythonSQL
Artificial Intelligence • Consumer Web • Information Technology • Real Estate • Software • PropTech
Build and deploy end-to-end ML models for renter acquisition, supply optimization, ranking, personalization, and marketplace optimization. Lead technical projects from problem framing through experimentation, launch, monitoring, and iteration. Apply statistical methods, causal inference, and rigorous A/B testing. Partner cross-functionally, mentor other data scientists, and raise modeling and experimentation standards.
Top Skills:
AirflowDbtGCPMlopsPythonPyTorchScikit-LearnSQLTensorFlowXgboost
Information Technology • Consulting
Build production AI retrieval and knowledge systems for rare disease research at NIH. Model biomedical ontologies in PostgreSQL, develop semantic search, retrieval-augmented services, ranking, evaluation, and observability, and deliver user interfaces with Next.js, React, and TypeScript. Deploy and operate services in on-premises and HPC Kubernetes environments, including GPU inference. Collaborate with NIH staff, clinicians, and researchers, and contribute to scientific publications.
Top Skills:
Ci/CdDockerFastapiFull-Text SearchGa4GhGitHelmHpoKubernetesLitellmLlm ApisMedcptMeshMondoNext.JsObo FoundryOllamaPgvectorPostgresPydanticPytestPythonReactStatefulsetsTypescriptUmlsVllm
Information Technology • Consulting
Build and operate agentic AI systems for rare disease research, including multi-turn workflows, structured and validated outputs, tool calling, prompt testing, evaluation suites, asynchronous execution, streaming, observability, and failure handling. Collaborate with NIH staff, clinicians, geneticists, researchers, and patient communities to translate needs into reliable data models and system behavior. Own components through deployment, establish AI engineering standards, and contribute to scientific manuscripts, abstracts, and conference posters.
Top Skills:
Anthropic Agent SdkArize PhoenixAsynchronous PythonBraintrustCi/CdConcurrent PythonDockerFastapiGitHpoKubernetesLangfuseLanggraphLangsmithLitellmLlm ApisMcpMeshMondoObo FoundryOllamaOpenai Agent SdkPostgresPydanticPydantic AiPytestPythonStreamingStructured GenerationTool CallingUmlsVector SearchVllm
Information Technology • Legal Tech • Professional Services • Analytics • Business Intelligence
Develop and deploy NLP and machine learning models for classification, sentiment analysis, entity extraction, information retrieval, and user intent detection across large-scale legal, financial, news, and business datasets. Design scalable data science pipelines, evaluate modern AI algorithms and tools, translate business needs into technical solutions, and collaborate with product and engineering teams. Mentor junior scientists and contribute to model deployment, monitoring, maintenance, and development best practices.
Top Skills:
Aws Ec2Aws LambdaCaffeCaffe2Deep LearningElasticsearchGensimInformation RetrievalJanusgraphJavaKerasLarge Language ModelsLdaMachine LearningMlopsMxnetNeptuneNlpNumpyOpennlpPandasPythonPyTorchScalaScikit-LearnSolrSpacySparkSQLStanford NlpTensorFlow
Cybersecurity
The role involves deploying data science solutions in cybersecurity, collaborating with customers and teams to operationalize models and enhance security insights.
Top Skills:
APIsGitPythonSQL
Big Data • eCommerce
Design, validate, and deploy scalable statistical and distributional models for enterprise consumer analytics. Implement rigorous methodologies, convert ad-hoc analyses into version-controlled analytical libraries, and partner with Data Engineering to optimize performance and scale compute workloads (including cloud/Databricks). Deliver reproducible analytics powering dashboards and LLM-driven applications, with a focus on panel and transaction-level consumer data.
Top Skills:
DatabricksLlm (Large Language Models)PythonRSQL
Insurance
Senior individual contributor responsible for leading pet/P&C insurance pricing model development (GLMs and ML), owning end-to-end projects, performing EDA and root-cause analysis, communicating results to stakeholders, and mentoring junior team members.
Top Skills:
GlmMachine LearningPythonRegression ModelingSQLStatistical Inference
Artificial Intelligence • Healthtech • Machine Learning
Develop and tune ML models, productionize and deploy strategies for ML systems, and align cross-functionally to communicate performance metrics.
Top Skills:
PysparkPythonPyTorchSQL
Travel
Lead end-to-end machine learning and advanced analytics projects: frame problems, build and deploy predictive/prescriptive models, design ETL pipelines, create dashboards and A/B test metrics, and deliver actionable insights to business stakeholders to improve fleet, pricing, and ridesharing products.
Top Skills:
BigQueryDatabricksETLEvent-Driven ArchitecturesPythonSQLStreaming DataTableau
Food
Develop, validate, and improve machine learning models (regression, classification, forecasting, optimization). Prepare data, perform feature engineering, train and evaluate models, and support deployment with Data/ML Engineering. Communicate results, document methods, and collaborate on experiments and cross-functional initiatives.
Top Skills:
AWSAzureGCPPythonPyTorchSQLTensorFlow
eCommerce • Insurance • Software
Lead end-to-end development of fraud and risk ML systems: define problems, engineer features, build and evaluate models, collaborate with product and engineering, deploy with ML engineers, and monitor production performance to detect drift and trigger retraining.
Top Skills:
PythonPyTorchScikit-LearnSQLXgboost
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Agency • Information Technology
Design, build, evaluate, and deploy predictive ML models across regression, classification, NLP, computer vision, and time-series problems. Perform data cleaning, feature engineering, EDA, model selection, tuning, explanation (SHAP, feature importance), and collaborate with engineers and stakeholders to operationalize and monitor models in production.
Top Skills:
AirflowAWSAzureCi/CdCnnComputer VisionDockerGitGCPGruKubeflowLstmMatplotlibMlflowNlpNumpyPandasPythonPyTorchRnnScikit-LearnScipySeabornShapSparkSQLTensorFlowTransformer
Insurance
As a Data Scientist III, you'll build customer identity systems, develop recommendation models, predictive analytics for customer behavior, and collaborate with ML Ops and Data Engineering.
Top Skills:
AirflowAws RdsDockerFastapiMetaflowPythonSagemakerScikit-LearnSnowflakeSQLSQL ServerXgboost
Machine Learning • Software
As a Staff Data Scientist, you will lead initiatives to build and optimize machine learning models, collaborate across departments, and solve complex business problems using data.
Top Skills:
LlmMlSQL
Greentech
As a Data Scientist, you will build predictive models, develop software tools, and analyze geoscientific data to support mineral exploration and discovery.
Top Skills:
Cicd PipelinesCloud ComputingCollaborative Software DevelopmentData Science PackagesGeospatial AnalysesGitMachine LearningPythonVisualizations
Greentech
The Data Scientist will develop predictive models, analyze geophysical data, and collaborate with geoscientists to enhance exploration programs, focusing on mineral deposits.
Top Skills:
Cicd PipelinesCloud ComputingData Science PackagesGeospatial AnalysesMachine LearningPython
Greentech
As a Data Scientist, you will develop predictive models, analyze geoscientific data, and collaborate with geoscientists to improve mineral exploration efforts.
Top Skills:
Cloud ComputingGeospatial AnalysisPythonSoftware Engineering
AdTech • Marketing Tech
Design, build, and deploy production-grade machine learning models and analytical solutions. Work end-to-end from problem definition to production, write performant Python and SQL, resolve data quality issues, collaborate with product and engineering, support on-call, automate reporting, mentor junior teammates, and improve model reliability and workflows.
Top Skills:
PythonSQL
Healthtech
Develop autonomous AI agents capable of goal setting, decomposition, planning, tool use, memory, and long-horizon execution. Build evaluation frameworks for alignment, reliability, and safety; identify goal misalignment and undesirable behaviors; and integrate agent systems with APIs, databases, search engines, and other tools. Responsibilities include designing production-ready machine learning systems, collaborating across teams, and advancing agent autonomy through planning, causal reasoning, model-based reinforcement learning, and language modeling.
Top Skills:
APIsAutogenCausal ReasoningDatabasesETLJaxLangchainLanggraphMcp ServersModel-Based Reinforcement LearningPythonPyTorchSearch EnginesSQLSymbolic PlanningTransformers
Cybersecurity
Owns the end-to-end development of cybersecurity vulnerability and exploit prediction models, including problem framing, feature engineering, training, evaluation, deployment, calibration, monitoring, and drift detection. The role addresses extreme class imbalance, hierarchical modeling, cold-start customers, and uncertainty quantification. It also requires explaining model outputs to security executives, publishing methodologies and benchmarks, and partnering with engineering to deploy reliable production systems.
Top Skills:
PythonSQL
Biotech • Pharmaceutical
Provides biostatistical data science and analytics support for clinical development and evidence generation. Collaborates with biostatistics, data management, clinical development, and medical affairs teams; applies statistics, mathematics, AI, and innovative technologies to clinical trial and real-world data. Contributes to clinical trial design, statistical analysis plans, clinical study reports, publications, and protocol development while following ICH and FDA guidelines.
Top Skills:
Generative Ai ToolsGitPythonRSAS
AdTech • Big Data • Consumer Web • Digital Media • Marketing Tech
Own end-to-end data science for a priority vertical (starting with Insurance): frame business problems, build and validate models, partner with ML engineering for deployment, monitor live ROAS performance, and drive measurable revenue and lead quality improvements.
Top Skills:
AWSCollaborative FilteringDeep LearningEmbeddingsGoogle AdsLlmsLookerLtv ModelingMeta AdsMulti-Armed BanditPythonRanking AlgorithmsRecommendation SystemsReinforcement LearningSQL
Big Data • Machine Learning • Social Impact • Software
Lead end-to-end data science projects including predictive modeling, algorithm design, and data pipelines. Build campaign-focused models (turnout, partisanship), perform exploration and visualization, translate insights into memos/presentations, collaborate with engineering to productionize models, mentor junior data scientists, and prototype emerging AI solutions for product impact.
Top Skills:
GitPythonSQL
Artificial Intelligence • Big Data • Internet of Things • Software
The Senior Data Scientist will lead innovative data science efforts, leveraging advanced analytics, visualization, and insights from complex datasets to boost productivity.
Top Skills:
PythonRScalaSQL
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