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Top Python Jobs in Charleston, SC
Big Data • Cloud • Software • Database
The Senior Python Engineer will develop and support MongoDB Python drivers, enhance library quality, and collaborate on product features.
Top Skills:
Ai/Ml FrameworksMongoDBPypiPython
Artificial Intelligence • Blockchain • Digital Media • Information Technology
Develop and maintain Python applications focusing on iterators/generators/streams, concurrency (multithreading, non-blocking I/O), and high-precision numeric handling. Work with JSON/XML, REST and SOAP APIs, ACID-compliant databases, message brokers/queues, and produce clean, SOLID code. Unit and integration testing experience is beneficial.
Top Skills:
Acid-Compliant DatabasesDecimal ModuleFractions ModuleGeneratorsIntegration TestingIteratorsJSONMessage BrokersMessage QueuesMulti-ThreadingNon-Blocking I/OParallelismPythonRegular ExpressionsRestSoapStreamsUnit TestingXML
Artificial Intelligence • Software • Consulting • Automation
Work as a Python development intern building applications and APIs, processing and analyzing data, working with databases and data pipelines, contributing to system architecture, writing clean documented code, and collaborating with the team. Strong emphasis on backend development, SQL, ORMs, and REST API design with potential conversion to full-time.
Top Skills:
DjangoDjango OrmFastapiFlaskGitGitHTTPJSONMySQLNumpyPandasPostgresPythonRest ApiSQLSqlalchemySqlite
Information Technology
Concept Plus seeks a Junior Python Developer to enhance enterprise-scale applications, focusing on backend development, DevSecOps practices, and secure coding under senior guidance.
Top Skills:
Ci/CdGitPyodidePythonRest ApisWebassembly
Agency • Information Technology • Software • App development
Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.
Top Skills:
AWSAzureAzure PipelinesCi/CdCosmosdbDjangoDockerFastapiFlaskGenerative AiGitlab CiGCPHugging FaceJenkinsKafkaKubernetesPythonPyTorchRabbitMQRdsRest ApisServerlessTensorFlowWebsockets
Artificial Intelligence • Information Technology • Professional Services • Software
The Senior Full Stack Developer will design, develop, test, and debug software solutions, collaborating with teams and optimizing applications. Responsibilities include user interaction design, back-end functionality, and ensuring software scalability and security.
Top Skills:
CSSDjangoDockerFastapiFlaskGitGnu/LinuxHTMLJavaScriptMongoDBMySQLNode.jsOraclePostgresPythonReactSvnVue
Logistics • Software • Transportation
The Principal Python Engineer will design, build, and maintain backend services and APIs, focusing on system reliability and engineering quality. The role involves working with databases, applying DevOps practices, and leveraging AI for development efficiency.
Top Skills:
DockerFastapiKubernetesPostgresPulumiPythonTemporalVue
Cloud • Software
The Python Engineer will write maintainable Python software, lead technical initiatives, collaborate globally, and contribute to community engagement at Canonical.
Top Skills:
CC++DockerGoKubernetesLinuxNoSQLPythonRustSQL
Artificial Intelligence • Information Technology • Machine Learning • Software • Virtual Reality • Analytics
Nagarro seeks an Associate Principal Engineer with extensive IT experience in Python to drive strategic value and innovation in product engineering.
Top Skills:
Python
Reposted YesterdaySaved
Big Data • Machine Learning • Software • Analytics
The Software Engineer will develop and maintain Alteryx's Intelligent Services cloud and on-prem product suite, focusing on design, development, and quality assurance.
Top Skills:
AIPythonReactTypescript
Legal Tech • Software
Design and implement durable, fault-tolerant AI orchestration and backend systems using Temporal and agentic ReAct patterns. Deliver features end-to-end with testing, CI/CD, monitoring, and observability; mentor engineers and collaborate with cross-functional teams to translate legal workflows into reliable AI-powered features.
Top Skills:
Async/AwaitClaude (Llm)Event-Driven ArchitectureFastapiGitlab Ci/CdMessage QueuesNew Relic ApmOctopus DeployPlaywrightPydantic V2Pydantic-AiPytestPython 3.12+ReactStructlogSyrupyTemporal
Artificial Intelligence • eCommerce • Software
Design and build backend systems and APIs for AI-driven products, ensuring scalability, reliability, and integration of ML models while collaborating with engineering and product teams.
Top Skills:
APIsAWSAzureDockerGCPKubernetesLlmsMachine LearningNoSQLPythonSQL
New
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Database • Analytics
As a Senior Software Engineer, you'll enhance ClickHouse's Python integrations, drive AI integration strategies, and collaborate with open-source communities, requiring deep expertise in data engineering and AI applications.
Top Skills:
Apache AirflowDagsterDbtLangchainLlamaindexN8NNumpyPandasPrefectPydanticPython
Digital Media • Professional Services • Consulting • Financial Services
The Senior Python Developer will enhance commerce and communication infrastructure by developing features, collaborating with stakeholders, ensuring system reliability, and integrating with third-party tools, while maintaining high-performance standards.
Top Skills:
Ci/CdDockerFastapiPostgresPythonRabbitMQRedisStripe
Artificial Intelligence • HR Tech • Information Technology • Software
As a Founding Staff Software Engineer, you will lead the design and development of robust backend systems and APIs, optimize large-scale data workflows, and mentor a growing engineering team.
Top Skills:
AWSCeleryFastapiOpensearchPostgresPythonRedisTemporal
Software • Cybersecurity
The Forward Deployed Engineer will serve as a technical bridge between clients and engineering teams, writing custom code and integrations, while ensuring customer success with Socket's security platform through strong relationships and expert technical guidance.
Top Skills:
Automation ScriptsCi/CdDevOpsPythonSastWebhook Implementations
Big Data • Machine Learning • Software • Analytics
The Staff Python Software Engineer will modernize legacy systems, design backend services, mentor engineers, and drive technical improvements in a remote role.
Top Skills:
AWSAzureC++DockerGCPKubernetesPython
Artificial Intelligence • Logistics • Software • Transportation
Design, develop, deploy, monitor, and support APIs and system integrations (Salesforce, REST, third-party). Work directly with clients to gather requirements, troubleshoot and optimize integrations, operate solutions in AWS, collaborate with teams, and mentor junior developers.
Top Skills:
Aws Api GatewayAws EcsAws LambdaAws RdsPythonRest ApiSalesforceSnsSqsTerraform
Information Technology • Logistics • Transportation • Consulting
Build and ship full‑stack features for transportation management and other client products. Design and implement APIs and UIs, collaborate with product and design, own delivery, write modular testable code, troubleshoot and iterate quickly, and mentor peers.
Top Skills:
.NetC#Ci/CdDevOpsDockerElectronFastapiGraphQLJavaJavaScriptLlmsLookmlMlMongoDBMySQLNode.jsPythonReact NativeReactRestSpringTypescriptVue
Software
Design, build, and maintain enterprise-quality Python serverless applications on AWS; integrate services and external APIs, implement state machines and CI/CD, write automated integration tests, troubleshoot and support production systems, and advise stakeholders on solutions.
Top Skills:
AutomationAWSCi/CdCloudFormationEcs FargateEsbIntegration TestingPostgresPythonRest ApisServerlessSQLState MachinesWorkflow Engine
Artificial Intelligence • Information Technology • Software • Consulting
Build and maintain full-stack product features alongside cross-functional teams, contribute across architecture tiers, write tested maintainable code, collaborate with product managers, participate in re-architecture and technical design, and use logging and performance techniques to ensure low-latency, reliable user experiences.
Top Skills:
AWSBigQueryDynamoDBGraphQLHTTPKafkaMySQLNeo4JNext.JsNode.jsOauthPostgresPythonRdsReactRestSnowflakeTypescriptVercel
Artificial Intelligence • Computer Vision • Machine Learning • Software
Build and maintain Django-based web applications, design RESTful APIs, implement frontend features (HTML/CSS/JS), optimize performance and security, collaborate with cross-functional teams throughout the development lifecycle.
Top Skills:
CSSDjangoGitHTMLJavaScriptMySQLPostgresPythonRestful Apis
Automotive
The Senior Software Engineer will build a large-scale data ingestion and classification system using web scraping, data processing, and search technologies, overseeing data extraction from various sources and developing search capabilities.
Top Skills:
AirflowAWSElasticsearchKubernetesOcrOpensearchPythonScrapySpark
Information Technology
The Senior Python Developer will design and implement secure backend systems using Python and Pyodide, ensuring compliance with DoD cybersecurity requirements and cloud deployment practices. Responsibilities include leading Python code optimization, supporting CI/CD pipelines, and participating in Agile sprint cycles, all while collaborating with cross-functional teams and ensuring secure coding standards.
Top Skills:
800-171APIsCi/CdCloud OneCmmcDevsecopsDisa StigsNist Sp 800-53PyodidePythonWebassemblyZero Trust
Travel
As a Staff Software Engineer, you’ll lead the design and reliability of Duetto's data lakehouse, evolving data systems using Python and AWS, ensuring data quality, and implementing AI-driven solutions.
Top Skills:
AirflowAWSDatadogDockerGithub ActionsGlueIcebergPysparkPythonSagemakerSentrySumo LogicTerraform
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