Top Senior IT Jobs in Charleston, SC

The Director of IT Applications leads the delivery of enterprise applications, ensuring that business systems effectively support operations across Finance, Sales, Marketing, HR, and more while driving automation and system improvements.

The Senior Network Engineer will design, implement, and secure global networking infrastructure, ensuring resilience and security across various environments. They will collaborate with IT, Security, and Engineering to support mission-critical operations and compliance with relevant frameworks.

Lead IT support operations, ensuring high-quality technical support, vendor management, and IT processes for a remote workforce while improving contributor experience.

The Senior Manager of Corporate Operations will lead technical strategy for internal systems, focusing on IAM, MDM, and corporate infrastructure, ensuring security and operational excellence across environments.

The Lead IT Telecom Architect designs and optimizes Telecom and Contact Center architecture to meet business goals, ensuring security and performance. Responsibilities include strategy development, technology evaluation, system implementation oversight, and stakeholder collaboration.

Lead large-scale IT initiatives for Carrier Enterprise Canada, managing full project lifecycle, roadmaps, budgets, vendors, risk, and stakeholder communication. Drive ERP migrations, digital transformation, automation, analytics and AI adoption, ensure compliance and cybersecurity, and champion change management across a country-wide distribution environment.

Lead design, implementation, and administration of enterprise IT infrastructure with a strong focus on identity and access management across GCP, AWS, and GitHub. Build Okta-driven provisioning workflows, automate processes, manage IAM governance and compliance, support IT support escalations, and evolve security policies including PAM and EDR controls.

Lead and operate Vynca's IT function for a fully remote, HIPAA-regulated healthcare organization. Manage a distributed IT team, own day-to-day operations (hardware lifecycle, provisioning, identity and access), enforce security and compliance (HIPAA, SOC 2), administer MDM/SSO/endpoint tools, support audits, and drive operational improvements while mentoring staff.

The Senior Technology Specialist oversees the design and support of technology solutions, ensuring they meet business needs and compliance standards, while mentoring junior staff and optimizing operations.

The Business Development Manager will focus on acquiring new clients and expanding accounts within the IT staffing sector, managing the full sales cycle and meeting revenue targets.

Lead design, implementation, and optimization of ServiceNow ITOM (Discovery, Service Mapping, Event Management) and CMDB governance. Configure MID Servers, patterns, probes, and integrations; manage cloud discovery across AWS/Azure/GCP; build automations with Flow Designer and APIs; perform performance and root-cause analysis; liaise with vendors; produce technical strategy, capacity planning, and translate technical solutions for business stakeholders.

Remote IT Manager responsible for analyzing, upgrading, and administering IT systems (networks, servers, email, backups), evaluating vendors and technologies, managing projects, tracking inventory, training staff, and providing technical support to improve operational efficiency.

Lead strategy and execution of IT Computer System Validation and QA for GxP-regulated IT systems. Develop CSV strategy, SOPs, risk management, change control, and training. Oversee validation, vendor qualification, audits/inspections, and compliance of ERP and lab systems throughout the system lifecycle.

The Enterprise Architect leads architectural strategy and integration for technology and processes while aligning IT investments with business goals. Responsibilities include overseeing cloud modernization, governance, and communication with stakeholders.

The Senior Clinical Trials IT Business Analyst bridges Clinical Development and IT, optimizing clinical trial technologies and managing system implementations, validations, and stakeholder engagement.

The Senior IT Systems Administrator oversees the administration, security, and optimization of financial systems, ensuring reliability and compliance while leading system enhancements and integrations.

The IT Category Manager, Biomed manages IT suppliers and oversees procurement strategies, aligning with IT and business needs while ensuring compliance and cost control.

Provide remote technical support, troubleshoot issues, design security solutions, manage cloud and virtualization environments, and communicate with clients. Requires strong IT skills and customer service.

Manage full project lifecycle for IT Operations and Services, including enterprise applications, security, network/systems infrastructure, and process improvements. Create plans, governance, change management, vendor onboarding, KPIs, roadmaps, and transition projects to operations while communicating status and driving cross-team collaboration.

Lead and manage Level 1-3 Service Desk analysts supporting external clients, oversee daily operations, escalations, SLAs, and reporting. Improve service management, automation, and first-call resolution; partner with Engineering and Incident/Problem/Change Management to resolve production issues. Provide hands-on technical leadership across Splunk, Datadog, MuleSoft, SQL, and ServiceNow while managing client communications and operational metrics.

The IT Operations Director leads Service Desk and Infrastructure teams, overseeing IT operations lifecycle, managing metrics, enforcing security, and enhancing service quality through automation and ITIL processes.

The Enterprise Architect defines technology strategies, aligns investments with company goals, and leads cloud modernization and data analytics initiatives while ensuring compliance and governance.

Manage SAP ERP solutions for finance, design and implement configurations, provide user support, and ensure integration across relevant business areas.

The Senior Director Analyst at Gartner leads research initiatives, providing thought leadership, actionable insights, and market analysis to clients and organizations, while mentoring junior team members.

The role involves leading and improving IT operations, focusing on proactive service organization, process design, and team development while managing IT projects and vendor relationships.