Top Senior IT Jobs in Charleston, SC

The Senior Technology Specialist oversees the design and support of technology solutions, ensuring they meet business needs and compliance standards, while mentoring junior staff and optimizing operations.

The Business Development Manager will focus on acquiring new clients and expanding accounts within the IT staffing sector, managing the full sales cycle and meeting revenue targets.

Lead design, implementation, and optimization of ServiceNow ITOM (Discovery, Service Mapping, Event Management) and CMDB governance. Configure MID Servers, patterns, probes, and integrations; manage cloud discovery across AWS/Azure/GCP; build automations with Flow Designer and APIs; perform performance and root-cause analysis; liaise with vendors; produce technical strategy, capacity planning, and translate technical solutions for business stakeholders.

Remote IT Manager responsible for analyzing, upgrading, and administering IT systems (networks, servers, email, backups), evaluating vendors and technologies, managing projects, tracking inventory, training staff, and providing technical support to improve operational efficiency.

Lead strategy and execution of IT Computer System Validation and QA for GxP-regulated IT systems. Develop CSV strategy, SOPs, risk management, change control, and training. Oversee validation, vendor qualification, audits/inspections, and compliance of ERP and lab systems throughout the system lifecycle.

The Enterprise Architect leads architectural strategy and integration for technology and processes while aligning IT investments with business goals. Responsibilities include overseeing cloud modernization, governance, and communication with stakeholders.

The Senior Clinical Trials IT Business Analyst bridges Clinical Development and IT, optimizing clinical trial technologies and managing system implementations, validations, and stakeholder engagement.

The Senior IT Systems Administrator oversees the administration, security, and optimization of financial systems, ensuring reliability and compliance while leading system enhancements and integrations.

The IT Category Manager, Biomed manages IT suppliers and oversees procurement strategies, aligning with IT and business needs while ensuring compliance and cost control.

Provide remote technical support, troubleshoot issues, design security solutions, manage cloud and virtualization environments, and communicate with clients. Requires strong IT skills and customer service.

Manage full project lifecycle for IT Operations and Services, including enterprise applications, security, network/systems infrastructure, and process improvements. Create plans, governance, change management, vendor onboarding, KPIs, roadmaps, and transition projects to operations while communicating status and driving cross-team collaboration.

Lead and manage Level 1-3 Service Desk analysts supporting external clients, oversee daily operations, escalations, SLAs, and reporting. Improve service management, automation, and first-call resolution; partner with Engineering and Incident/Problem/Change Management to resolve production issues. Provide hands-on technical leadership across Splunk, Datadog, MuleSoft, SQL, and ServiceNow while managing client communications and operational metrics.

The IT Operations Director leads Service Desk and Infrastructure teams, overseeing IT operations lifecycle, managing metrics, enforcing security, and enhancing service quality through automation and ITIL processes.

The Enterprise Architect defines technology strategies, aligns investments with company goals, and leads cloud modernization and data analytics initiatives while ensuring compliance and governance.

Manage SAP ERP solutions for finance, design and implement configurations, provide user support, and ensure integration across relevant business areas.

The Senior Director Analyst at Gartner leads research initiatives, providing thought leadership, actionable insights, and market analysis to clients and organizations, while mentoring junior team members.

The role involves leading and improving IT operations, focusing on proactive service organization, process design, and team development while managing IT projects and vendor relationships.

Hands-on senior IT systems administrator responsible for administering Google Workspace and Microsoft 365 environments, endpoint and MDM support across ChromeOS/Windows/macOS, SaaS administration, help desk support, and executing compliance controls (CMMC/NIST800-171/ISO27001/SOC2). Uses AI tools to automate IT workflows, supports engineering teams' toolchains, and assists in audit readiness and evidence collection.

The IT Operations Manager will oversee day-to-day IT operations, including managing MSP, network and cloud infrastructure, identity management, systems administration, and user support, while ensuring security and optimal performance across all platforms.

The Senior IT Project Manager will lead client-facing IT infrastructure projects, manage timelines and expectations, and coordinate engineering teams while ensuring high-quality delivery of services.

Responsible for IT support and administration for Commercial systems. Partners with business owners to ensure system performance, compliance, and operational excellence across various business functions.

The Senior IT Engineer will provide advanced technical support, manage IT infrastructures, ensure security, and lead incident response efforts in a remote environment.

The IT Support Lead oversees L1/L2 IT support operations, leading a team, ensuring effective issue resolution, and managing IT support functions.

Lead and manage a remote US IT support team to deliver high-quality technical support. Oversee daily operations, SLAs, ticket triage, knowledge base, training, metrics reporting, and escalation for complex issues while coordinating cross-functional initiatives and adopting industry best practices to improve customer satisfaction.

Lead and grow a product support team for a live digital court reporting product (Maggie). Supervise analysts, triage and lead incident response for P0/P1 events, coordinate escalations to IT and engineering, run on-call rotations, develop runbooks/KB/training, track support metrics, provision hardware kits, and hire and train support staff.