Top Senior IT Jobs in Charleston, SC

Serve as first-line IT support for hardware, software, networking, and enterprise applications. Triage and resolve support tickets, manage onboarding/offboarding, administer Okta and endpoint management (Intune, Jamf), maintain device health and access controls, collaborate with Security and Engineering, document processes, and improve support workflows to ensure a secure, compliant, and user-friendly hybrid work environment.

The role involves designing and developing enterprise-grade software solutions, integrating AI tools, collaborating with teams, and maintaining documentation while enhancing productivity for Yahoo personnel.

Support global infrastructure as an SME across databases, servers, networks, storage, and application platforms. Provide medium-to-high complexity run-the-business support, incident resolution, project resources, requirements gathering, solution implementation, knowledge articles, and mentoring. Cover 24/7 shifts as required.

Provide administration, maintenance, development, and troubleshooting for Oracle IAM (OAM, OIG, OID, OIM) including provisioning, authentication, RBAC/ABAC controls, custom Java/REST integrations, BI Publisher reporting, and IAM continuous monitoring. Produce SOPs, coordinate with SMEs, and apply secure coding and audit practices to support production and non-production environments.

Design and guide secure, scalable enterprise and cloud architectures (DNS, Azure, AWS, on-prem). Lead cloud migrations, implement monitoring, integrate hybrid environments, present technical briefings, and mentor staff while ensuring security and performance for a mission-focused government client.

Lead Data QA for the Enterprise Data Warehouse: define QA strategy, design and execute source-to-target validations, CDC and ETL checks, data masking verification, build quality dashboards and automations, mentor QA analysts, manage defects and release readiness, and collaborate with Data Engineering, BI, Product, and stakeholders to ensure data is accurate, complete, and audit-ready.

Senior IT leader partnering with Commercial leadership to define and deliver pharma commercial technology strategy, oversee Veeva and digital platforms, lead product launch technology readiness, manage vendors/agencies, ensure compliance and governance, and lead IT teams to deliver scalable, secure commercial applications and digital experiences.

Lead enterprise IT sourcing and software procurement for complex renewals and strategic sourcing initiatives. Drive savings, establish governance, create vendor strategies and KPIs, partner with IT and stakeholders, mentor procurement staff, and manage contract negotiations and renewals.

Lead and mentor the Infrastructure team and deliver the enterprise infrastructure roadmap. Design and maintain resilient on-prem and cloud (Azure) network and server environments, oversee capacity planning, monitoring, backup/recovery, disaster recovery, vendor management, and infrastructure automation. Support ERP/Sage X3 infrastructure, collaborate with InfoSec on vulnerability remediation and OT teams for manufacturing environments, and manage infrastructure projects and on-call escalations.

Lead front-end development using React and JavaScript to build responsive, high-performance web applications. Collaborate with UX designers, build reusable components, implement dynamic forms and drag-and-drop features, optimize for cloud deployment and security, mentor junior developers, and maintain design standards and testable, maintainable code.

Design, deploy, and maintain enterprise Identity Provider (IdP) and ADFS services for DoD-scale authentication. Implement and troubleshoot SAML/OAuth/OIDC federation, MFA, PKI/CAC authentication, claims/policy mappings, SSO, and high-availability architectures. Integrate applications, manage federation trusts, produce documentation, and collaborate with cybersecurity, AD, cloud, and application teams to support Zero Trust and identity modernization.

Design, deploy, and sustain enterprise Identity Provider (IdP) services and ADFS infrastructure for DoD-scale authentication. Implement and troubleshoot SAML/OAuth/OIDC/WS-Fed, PKI and certificate-based/MFA authentication, manage federation trusts, support SSO and onboarding, and produce technical documentation while collaborating with cybersecurity, AD, cloud, and application teams to ensure highly available, secure authentication services.

Lead end-to-end deployments of Medicaid MMIS/MES and related Health IT systems. Plan, schedule, and manage go-lives, deployment readiness, integrations, and installation of network equipment. Maintain implementation plans, coordinate cross-functional teams and stakeholders, ensure CMS/state compliance, and provide status reporting. Remote role with 25–50% travel.

Serve as embedded IT risk partner for engineering and technology teams, owning IT SOX readiness, control design, testing coordination, remediation oversight and auditor liaison. Assess ITGCs and application controls across cloud, DevOps, CI/CD, IAM and Kubernetes environments. Drive control automation, continuous monitoring, evidence quality, and translate technical risks into practical guidance for engineers, Finance, and external auditors.

Hunt and close net-new enterprise and mid-market US-headquartered clients with European operations for multi-country IT hardware procurement. Build pipeline via outbound prospecting, qualify opportunities, create proposals, manage CRM and forecasts, collaborate with regional teams and vendors, represent Presidio at events, and meet revenue and margin targets.

Lead and govern global IT change management lifecycle: intake, risk-based assessment, approvals, execution, validation, post-change review, reporting, and continuous improvement. Coordinate across IT teams, vendors, MSPs, and regions to minimize service disruption, maintain audit-ready records, deliver training, and drive tooling and process automation opportunities to support high-availability and data center operations.

Lead and sustain large-scale HPC systems supporting NOAA/NWS forecasting. Manage scheduler/software stack (PBS Pro/Slurm), optimize performance and throughput, troubleshoot multi-node Linux clusters, develop scripts, and support 24/7 operations with occasional travel and on-call duties.

Perform risk-based IT security and compliance audits (policy, general controls, firewall) against FFIEC/GLBA and other guidelines; coordinate assessments, report findings, assist sales, and perform onsite testing with up to 25% travel.

Lead integration of technology into information systems, design data warehouse and BI capabilities, define data architecture and dictionaries, centralize disparate data, design dashboards, document system architecture, perform data quality and management, and provide solution engineering, pilots, and enablement for analytics and resource management.

Responsible for IT support and administration for Commercial systems. Partners with business owners to ensure system performance, compliance, and operational excellence across various business functions.

Own vendor procurement, contracts, provisioning, and IT strategy for employee hardware/software. Manage SSO/onboarding/offboarding, device management, SOC2 audit evidence, vendor negotiations, cost audits, and automation of provisioning processes.

Lead IT SOX controls testing for ITGCs (access, change, operations) across blockchain-native and enterprise systems. Build testing programs, validate remediation, perform root-cause analysis, report to Audit Committee, and collaborate with Engineering, Security, and external auditors to ensure SOX compliance and scalable audit processes.