Top Senior IT Jobs in Charleston, SC

2 Days AgoSaved
Remote
Charleston, SC
75K-94K Annually
Senior level
75K-94K Annually
Senior level
Big Data • Cloud • Hardware • Software • App development
Develop and support Oracle EBS R12 and Oracle Cloud ERP finance modules. Build PL/SQL packages, reports, data models, and integrations; perform root-cause analysis, testing, patching, documentation, and collaborate with stakeholders to deliver scalable technical solutions.
Top Skills: Bi PublisherJavaJavaScriptOracle Cloud ErpOracle Data Integrator (Odi)Oracle Ebs R12Oracle FormsOracle ReportsOracle Soa SuitePl/SqlPythonSQLSql LoaderUnix Shell ScriptingWeb AdiWebmethodsWorkflows
2 Days AgoSaved
Remote
Charleston, SC
136K-203K Annually
Senior level
136K-203K Annually
Senior level
Fintech • Insurance • Financial Services
Manage and mentor multiple software development teams to deliver complex, high-quality applications. Oversee planning, execution, budgets, risks, and technical direction. Drive adoption of best practices, CI/CD, DevOps, cloud architectures (Azure), microservices, and scaled agile delivery. Collaborate with senior leadership, product owners, and vendors to align development with business goals, and lead performance management, career development, and process improvements.
Top Skills: AzureC#Ci/CdDevOpsJavaMicroservicesPythonRestful ApisScaled AgileVersion Control (Git)
Reposted 3 Days AgoSaved
Remote
Charleston, SC
68K-80K Annually
Senior level
68K-80K Annually
Senior level
Social Impact
The Project & IT Budget Analyst manages project coordination and IT budget oversight, supporting strategic initiatives and ensuring financial accuracy.
Top Skills: MS OfficeSmartsheet
Reposted 3 Days AgoSaved
Remote
Charleston, SC
222K-266K Annually
Senior level
222K-266K Annually
Senior level
Big Data • Information Technology • Software • Database • Analytics • Infrastructure as a Service (IaaS) • Big Data Analytics
As Director of IT, you'll lead IT services including Helpdesk, identity, and corporate infrastructure, focusing on automation, user experience, and team growth.
Top Skills: AWSAzureGCPGoogle WorkspaceIntuneJAMFMerakiOktaSd-WanSlackZoomZtna
Reposted 3 Days AgoSaved
Remote
Charleston, SC
78K-120K Annually
Senior level
78K-120K Annually
Senior level
Consulting
The IT Project Manager will oversee large-scale IT projects for public sector clients, ensuring deliverables meet project goals, timelines, and budgets while applying project management best practices.
Top Skills: AgileMS OfficeMs ProjectSoftware Development Life CycleWaterfall
Reposted 4 Days AgoSaved
Remote
Charleston, SC
104K-150K Annually
Senior level
104K-150K Annually
Senior level
Artificial Intelligence • Healthtech • Software
Serve as first-line IT support for hardware, software, networking, and enterprise applications. Triage and resolve support tickets, manage onboarding/offboarding, administer Okta and endpoint management (Intune, Jamf), maintain device health and access controls, collaborate with Security and Engineering, document processes, and improve support workflows to ensure a secure, compliant, and user-friendly hybrid work environment.
Top Skills: Infrastructure As CodeIntuneJAMFmacOSOktaSaaSWindows
Reposted 4 Days AgoSaved
Remote
Charleston, SC
100K-120K Annually
Senior level
100K-120K Annually
Senior level
Information Technology • Software • Analytics
The Senior IT Engineer will lead IT architecture and security processes, manage identity and access, and mentor team members while ensuring compliance and operational efficiency.
Top Skills: EdrGoogle WorkspaceMdmOidcOktaSAMLScim
Reposted 4 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Healthtech
The Senior IT Program Manager leads program development and implementation, ensuring projects align with business needs and are delivered on time and budget. They manage stakeholder relationships and facilitate communication with senior leadership, oversee financial management, and develop risk management strategies.
Top Skills: ConfluenceJIRAMicrosoft ProjectMS OfficeSnow Spm
Reposted 4 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Marketing Tech • Consulting
The IT IMO Program Manager will lead IT and Cyber integration activities for a business acquisition, ensuring governance, coordination, and successful delivery across multiple workstreams.
Top Skills: CybersecurityIntegration ManagementIt GovernanceSmartsheet
Reposted 4 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Fintech • Software • Financial Services
The Manager of Internal Audit (IT) leads audit engagements, supervises staff, and develops risk-based audit schedules while ensuring compliance with regulatory standards.
Top Skills: Bank AuditCobitComputer Assisted Audit TechniquesData AnalyticsIt AuditIt General ControlsNist
Reposted 4 Days AgoSaved
Remote
Charleston, SC
140K-150K Annually
Senior level
140K-150K Annually
Senior level
Healthtech • Pharmaceutical
The IT Systems Engineer III will improve Ophelia's IT systems through integration, automation, and security while managing IT projects, overseeing service providers, and ensuring compliance.
Top Skills: AIDlpDns AdministrationEdrGoogle Cloud PlatformIdp/IamItsmMdmSAMLScimZtna
Reposted 4 Days AgoSaved
Remote
Charleston, SC
190K-215K Annually
Senior level
190K-215K Annually
Senior level
Biotech
The Director of IT Business Enablement will lead partnerships with manufacturing leaders to drive technology strategies, optimize processes, and promote operational excellence across the organization.
Top Skills: ErpLimsManufacturing Execution Systems
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Reposted 4 Days AgoSaved
Remote
Charleston, SC
190K-215K Annually
Senior level
190K-215K Annually
Senior level
Healthtech
Lead global IT business enablement for Manufacturing and Quality, forging partnerships, driving innovation, and ensuring operational excellence through technology.
Top Skills: Advanced AnalyticsAutomationDigital TechnologiesErpLimsManufacturing Execution Systems
Reposted 4 Days AgoSaved
Remote
Charleston, SC
190K-215K Annually
Senior level
190K-215K Annually
Senior level
Healthtech • Other • Software • Biotech
The role leads IT Business Enablement, partnering with senior leaders to drive operational excellence in Manufacturing and Quality through technology and agile practices.
Top Skills: ErpLimsManufacturing Execution Systems
Reposted 4 Days AgoSaved
Remote
Charleston, SC
161K-350K Annually
Senior level
161K-350K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
The role involves designing and developing enterprise-grade software solutions, integrating AI tools, collaborating with teams, and maintaining documentation while enhancing productivity for Yahoo personnel.
Top Skills: AWSDockerGCPJavaKubernetesPython
Reposted 5 Days AgoSaved
Remote
Charleston, SC
125K-175K Annually
Senior level
125K-175K Annually
Senior level
Insurance
The Director of IT Applications leads the delivery of enterprise applications, ensuring that business systems effectively support operations across Finance, Sales, Marketing, HR, and more while driving automation and system improvements.
Top Skills: ConfluenceJIRAOracle NetsuiteSalesforceServicenow
Reposted 5 Days AgoSaved
Remote or Hybrid
Charleston, SC
130K-180K Annually
Senior level
130K-180K Annually
Senior level
Aerospace
The Senior Network Engineer will design, implement, and secure global networking infrastructure, ensuring resilience and security across various environments. They will collaborate with IT, Security, and Engineering to support mission-critical operations and compliance with relevant frameworks.
Top Skills: AWSCloudFormationDnsMdmTerraformVpcVpnZero TrustZscaler
Reposted 5 Days AgoSaved
In-Office or Remote
Charleston, SC
Senior level
Senior level
Blockchain • Fintech • Software • Financial Services • Cryptocurrency
Lead IT support operations, ensuring high-quality technical support, vendor management, and IT processes for a remote workforce while improving contributor experience.
Top Skills: APIsDnsIt Administration ToolsSaas SolutionsVpns
Reposted 5 Days AgoSaved
Remote
Charleston, SC
135K-165K Annually
Senior level
135K-165K Annually
Senior level
Machine Learning • Productivity • Sales • Software
The Senior Manager of Corporate Operations will lead technical strategy for internal systems, focusing on IAM, MDM, and corporate infrastructure, ensuring security and operational excellence across environments.
Top Skills: APIsBashGoogle WorkspaceIntuneJAMFMerakiMicrosoft O365Mobile Device ManagementOktaPythonVerkada
Reposted 6 Days AgoSaved
Remote
Charleston, SC
105K-179K Annually
Senior level
105K-179K Annually
Senior level
Healthtech • Pharmaceutical
The Lead IT Telecom Architect designs and optimizes Telecom and Contact Center architecture to meet business goals, ensuring security and performance. Responsibilities include strategy development, technology evaluation, system implementation oversight, and stakeholder collaboration.
Top Skills: AWSCcaasCloud ServicesUcaasVoip
17 Days AgoSaved
In-Office
Charleston, SC
Senior level
Senior level
Professional Services • Retail • Industrial • Manufacturing
Lead large-scale IT initiatives for Carrier Enterprise Canada, managing full project lifecycle, roadmaps, budgets, vendors, risk, and stakeholder communication. Drive ERP migrations, digital transformation, automation, analytics and AI adoption, ensure compliance and cybersecurity, and champion change management across a country-wide distribution environment.
Top Skills: Business IntelligenceErpGenerative AiInfor Cloudsuite Distribution (Csd)SalesforceService CloudTransportation Management SystemsWarehouse Management Systems
7 Days AgoSaved
Remote
Charleston, SC
137K-171K Annually
Senior level
137K-171K Annually
Senior level
Marketing Tech
Lead design, implementation, and administration of enterprise IT infrastructure with a strong focus on identity and access management across GCP, AWS, and GitHub. Build Okta-driven provisioning workflows, automate processes, manage IAM governance and compliance, support IT support escalations, and evolve security policies including PAM and EDR controls.
Top Skills: Aws IamBashBeyondtrustCloudFormationCyberarkEdrExcelFederated AccessGcp Iam (Cloud Identity)Github EnterpriseGoogle SheetsIam Identity CenterIntuneJAMFOktaOkta WorkflowsPythonSAMLScimSsoTerraformWorkato
7 Days AgoSaved
Remote
Charleston, SC
135K-140K Annually
Senior level
135K-140K Annually
Senior level
Healthtech
Lead and operate Vynca's IT function for a fully remote, HIPAA-regulated healthcare organization. Manage a distributed IT team, own day-to-day operations (hardware lifecycle, provisioning, identity and access), enforce security and compliance (HIPAA, SOC 2), administer MDM/SSO/endpoint tools, support audits, and drive operational improvements while mentoring staff.
Top Skills: Cloud Collaboration ToolsE-VerifyEndpoint SecurityHipaaHitrustIdentity And Access ManagementMdmMobile Device ManagementSingle Sign-OnSoc 2Sso
Reposted 7 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Financial Services
The Senior Technology Specialist oversees the design and support of technology solutions, ensuring they meet business needs and compliance standards, while mentoring junior staff and optimizing operations.
Top Skills: AutomationAWSEnterprise ApplicationsMicrosoft 365AzureScriptingSecurity TechnologiesVirtualization
Reposted 8 Days AgoSaved
Remote
Charleston, SC
80K-120K Annually
Senior level
80K-120K Annually
Senior level
Artificial Intelligence • Information Technology • Consulting
The Business Development Manager will focus on acquiring new clients and expanding accounts within the IT staffing sector, managing the full sales cycle and meeting revenue targets.
Top Skills: It StaffingMspVms
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