Top Chief of Staff Jobs

Serve as strategic partner to the President & CEO, oversee programmatic operations across youth development, reentry, wellness, and workforce initiatives; supervise program leaders; ensure compliance with funder requirements; coordinate cross-functional projects, performance management, and community partnerships to advance organizational priorities and program outcomes.

The Chief of Staff will manage various projects, support the CEO in company operations, and ensure the team achieves objectives across departments.

The Chief of Staff will support the CEO and leadership team, manage stakeholder relationships, build content and communicate data-driven insights, and drive organization within the team. They will also lead special projects and help in recruiting and team culture initiatives.

The Chief of Staff at UpEquity will drive strategic initiatives, improve organizational effectiveness, and support the executive team in decision-making while managing cross-functional projects and operational improvements.

Operate the CEO's operating system: set and own measurable company goals, run weekly leadership meetings, maintain company-level reporting sourced from the data warehouse, manage high-stakes cross-functional projects, prep executive and investor materials, and pressure-test decisions to ensure follow-through and outcomes.

The Chief of Staff will work closely with the CEO in key business functions such as strategy, recruiting, and operations. The role requires exceptional interpersonal skills, strategic thinking, and a passion for health. Responsibilities include recruiting, investor relations, internal communications, brand management, and special projects, adapting to the needs of the company.

Serve as a scientific and strategic partner to the Executive Director, synthesizing technical information, owning the directors operating rhythm, driving cross-disciplinary scientific programs from inception to execution, facilitating collaborations, preparing high-quality meeting materials and external communications, and handling confidential organizational and scientific matters with discretion.

Own the company's operating cadence, accelerate decision-making, lead high-priority cross-functional projects, and manage OKRs to ensure strategic accountability and scalable operations.

Partner with the CEO to drive enterprise strategy and execution, lead cross-functional initiatives, optimize CEO time and executive team operations, manage board and investor relations, establish KPIs, identify process improvements, and represent the CEO in select meetings.

Serve as strategic partner and proxy to the Co‑Heads of Global Investments, driving alignment across stakeholders, shaping leadership meetings, prioritizing HOI time, reviewing executive materials, and enabling cross‑functional initiatives. Act as a trusted advisor, influence without authority, and ensure decision‑ready communications while coordinating logistics, briefings, and events to advance investment priorities and executive objectives.

As Chief of Staff, coordinate strategic initiatives, advise the CEO, manage operations, and represent leadership in communications. Requires strong organizational and executive communication skills.

Serves as a strategic operating partner to the CEO and COO, translating priorities into action plans, tracking cross-functional deliverables, and improving business workflows. The role coordinates departments, analyzes sales and operational data, maintains executive reporting and trackers, supports sales collateral and field teams, and manages events, tastings, sponsorships, and trade shows. It also identifies process gaps, facilitates accountability, and supports basic HR coordination and special projects across the organization.

Partner with the founders and leadership team to operate Holly’s next growth phase. Own financial planning, forecasts, cash management, SaaS metrics, board reporting, company-wide KPIs, and planning cadences. Lead ambiguous, cross-functional initiatives from definition through execution, build new business functions, improve processes, support fundraising and external relationships, oversee People Operations, and strengthen company culture through events and initiatives.

The Chief of Staff will support the Managing Director of AI, driving AI transformation, designing automated systems, managing client engagements, and ensuring effective delivery and operational strategies within the organization.

The Chief of Staff for Operations will support the COO by driving execution, establishing priorities, and leading cross-functional initiatives to enhance organizational performance.

Support the executive by cutting administrative workload 50% within 30 days, convert tribal knowledge into SOPs, manage weekly/6-month/2-year OKRs and org chart, configure productivity tools, proactively solve problems, and ensure clear, error-free communication across teams.

Serve as a strategic operator and force multiplier for the CEO and leadership team. Drive cross-functional initiatives, prepare Board and investor materials, enable AI adoption and build workflows, support finance and revenue analytics, coordinate leadership rhythms and company offsites, and translate executive priorities into measurable plans and follow-through.

The Chief of Staff will support the COO by managing operations, driving performance culture through data, and overseeing partnerships. Responsibilities include leading operational rollouts and defining KPIs.

The Chief of Staff will assist the CEO across product, marketing, and operations by handling various responsibilities as needed, including customer support and data analysis.

The Chief of Staff will work closely with the President & CEO to drive strategic initiatives, enhance organizational effectiveness, and represent the leadership in key discussions, ensuring alignment across the enterprise.

Serve as Chief of Staff to the CEO/CBO and lead the Strategy & Operations team, driving enterprise strategy, cross-functional initiatives, executive communications, and high-priority projects. Build and scale a high-performing S&O team, set operating standards, recruit and develop talent, and ensure follow-through on critical decisions. Act as a trusted advisor, translating strategy into execution and improving organizational effectiveness.

Support the CEO and President by coordinating executive priorities, preparing board and executive materials, driving cross-functional strategic initiatives, improving operating rhythms, and tracking progress on company priorities. Act as a central coordinator for communication, decision-support, and follow-through across leadership teams to scale organizational effectiveness during the companys transition to commercial-stage.

The Chief of Staff will drive project execution, manage leadership schedules, provide strategic insights, and enhance operational efficiency while facilitating team collaboration.

The Chief of Staff will assist the CEO by executing growth initiatives, managing projects, and fostering cross-departmental alignment in a dynamic environment.

The Chief of Staff to the CEO will manage the company's operating system, drive strategic projects, facilitate communication, and align leadership priorities with a strong commitment to healthcare access.