Top Chief of Staff Jobs

Partners with the EVP of Revenue to define go-to-market priorities, manage operating cadences, align Sales, Marketing, RevOps, Finance, and Product, and drive strategic initiatives. Tracks pipeline, conversion, quota attainment, and capacity signals; identifies risks and corrective actions; prepares board and QBR materials; facilitates leadership meetings; and ensures execution of high-impact revenue projects.

The Chief of Staff will support the CEO in GTM operations, enhance cross-functional clarity, and act as an external representative for Onehouse, driving company growth through strategic execution and operations management.

The Chief of Staff partners with the CEO and senior leadership to translate strategy into execution, manage operating rhythms, drive cross-functional initiatives, track accountability, and improve organizational clarity. Responsibilities include executive communications, strategic program delivery, research and due diligence, leadership and culture support, event coordination, process scaling, and daily use of AI tools for analysis, drafting, automation, and productivity.

Serve as the CEO’s commercial and execution partner, owning ambiguous special projects across acquisitions, fundraising, executive hiring, partnerships, GTM initiatives, communications, and new business lines. Scope initiatives rapidly, coordinate cross-functional teams, remove blockers, and deliver results end-to-end. The role requires founder-level ownership, strong commercial judgment, crisp communication, discretion, and experience operating in high-growth startup or scale-up environments.

The Chief of Staff will support the executive team by managing schedules, facilitating communication, and overseeing internal operations to enhance productivity.

Serve as a strategic partner to the CEO and executive team by coordinating company priorities, OKRs, QBRs, executive meetings, strategic initiatives, and cross-functional projects. Develop business cases and transition plans, lead high-impact execution, support board preparation, and create organizational structure and operating cadence. The role requires strong judgment, communication, confidentiality, emotional intelligence, and project leadership.

Chief of Staff will work directly with the founders to translate priorities into execution, manage cross-functional workstreams, strengthen operating systems, and ensure commitments are completed. Responsibilities include customer success coordination, pipeline management, market and policy research, investor and board support, internal communications, hiring coordination, and preparation for external meetings. The role requires strong organization, judgment, discretion, communication, project management, and comfort operating in a fast-paced, in-person startup environment.

Partners with the CEO to drive strategic execution, cross-functional alignment, business operations, and executive leverage. Translates company priorities into action plans, tracks progress, prepares decision materials, analyzes financial and operational performance, coordinates communications, and manages high-priority initiatives. The role requires strong organization, judgment, discretion, analytical ability, and communication skills while operating across functions including Finance, Product, Engineering, GTM, and Operations.

The Chief of Staff supports Financial Advisors by managing business operations, overseeing support professionals, and enhancing client relationships. Key responsibilities include coordinating strategic initiatives, managing client communications, and leading team performance efforts.

Serve as the right hand to the Head of Sales, running sales cadence, driving pipeline visibility and forecasting, enabling reps with materials, coordinating cross-functional GTM work, structuring strategic problems, supporting hiring/onboarding, and preparing executive-level communications to improve sales execution and accountability.

Partner with the CFO to prioritize and advance high-impact finance, people, operations, and strategy work. Shape operating cadence, prepare executive materials, track CFO-owned projects to closure, coordinate cross-functional stakeholders, resolve stalled work, and draft decision notes and executive communications to maintain momentum and clarity across the CFO portfolio.

Support the CEO and executive team with admin, sales/marketing, finance, and logistics. Manage and execute special projects, coordinate cross-functional meetings, prepare reports and presentations, act as liaison between leadership and departments, monitor progress, and research opportunities to align company strategy and improve performance.

Work directly with the founders to drive high-priority, cross-functional initiatives end-to-end. Manage operating rhythm (OKRs, leadership meetings), coordinate demos, manufacturing, fundraising, government relations, and hiring. Represent founders to defense stakeholders, organize high-urgency field missions and events, and streamline processes while operating in extreme ambiguity with frequent travel.

Leads multidisciplinary engineering teams developing and transitioning advanced autonomy, JADC2, and battle management technologies. Serves as technical authority, directs requirements and cross-project integration, interfaces with customers and senior leadership, chairs technical reviews, manages technical risks and performance, and mentors engineering staff. Requires extensive STEM experience, active Secret clearance, and eligibility for SAP and TS/SCI access.

Serve as Chief of Staff to Senior Private Wealth Advisors, managing stakeholder communications, calendar and travel logistics, expense processing, meeting preparation, and leading client events and digital marketing. Drive operational excellence, project management, and high-touch client service while supporting principals and coordinating internal partners.

Serve as strategic partner to the President & CEO, oversee programmatic operations across youth development, reentry, wellness, and workforce initiatives; supervise program leaders; ensure compliance with funder requirements; coordinate cross-functional projects, performance management, and community partnerships to advance organizational priorities and program outcomes.

The Chief of Staff will manage various projects, support the CEO in company operations, and ensure the team achieves objectives across departments.

The Chief of Staff will support the CEO and leadership team, manage stakeholder relationships, build content and communicate data-driven insights, and drive organization within the team. They will also lead special projects and help in recruiting and team culture initiatives.

Serve as Chief of Staff to the VP of Neuroscience Discovery Research, translating strategy into action by coordinating cross-functional initiatives, tracking progress, identifying risks, and enabling decision-making. Drive operational excellence, support leadership effectiveness, develop executive communications, and partner with Finance and Business Management to prioritize resources and improve processes. Facilitate external collaborations and capture organizational learnings to strengthen alignment and execution across discovery research teams.

The Chief of Staff at UpEquity will drive strategic initiatives, improve organizational effectiveness, and support the executive team in decision-making while managing cross-functional projects and operational improvements.

Operate the CEO's operating system: set and own measurable company goals, run weekly leadership meetings, maintain company-level reporting sourced from the data warehouse, manage high-stakes cross-functional projects, prep executive and investor materials, and pressure-test decisions to ensure follow-through and outcomes.

The Chief of Staff will work closely with the CEO in key business functions such as strategy, recruiting, and operations. The role requires exceptional interpersonal skills, strategic thinking, and a passion for health. Responsibilities include recruiting, investor relations, internal communications, brand management, and special projects, adapting to the needs of the company.

Serve as a scientific and strategic partner to the Executive Director, synthesizing technical information, owning the directors operating rhythm, driving cross-disciplinary scientific programs from inception to execution, facilitating collaborations, preparing high-quality meeting materials and external communications, and handling confidential organizational and scientific matters with discretion.

Own the company's operating cadence, accelerate decision-making, lead high-priority cross-functional projects, and manage OKRs to ensure strategic accountability and scalable operations.

Partner with the CEO to drive enterprise strategy and execution, lead cross-functional initiatives, optimize CEO time and executive team operations, manage board and investor relations, establish KPIs, identify process improvements, and represent the CEO in select meetings.