Top Remote Software Engineer Jobs in St. Louis, MO

Design and modernize scalable distributed systems for insurance eligibility, claims, and remittance workflows. Develop full-stack applications using React or Angular and .NET, optimize SQL Server databases, and lead end-to-end Epic delivery. Champion AI-assisted engineering, automated testing, CI/CD, code quality, system reliability, and technical mentorship while managing dependencies, DORA KPIs, and stakeholder communication.

Build and own Pepper’s regulated audit platform across internal auditor tools, client and partner portals, data models, integrations, security, and reliability. Develop end-to-end features using TypeScript, React, Node.js, PostgreSQL, and Supabase. Design secure multi-tenant data isolation, authentication, audit logging, evidence integrity, integrations, observability, CI/CD, and deployment workflows. Partner with founders, auditors, CPAs, engineers, and external partners in a high-autonomy environment.

Design and implement high-performance distributed Rust systems for autonomous, human-machine-AI teaming in constrained and contested environments. Responsibilities include architecture, hardware and microcontroller integration, networking, deterministic build infrastructure, OTA updates, simulation and field testing, performance optimization, and deployment of reliable edge systems. The role supports mission-critical defense applications and requires collaboration across engineering, research, and operational teams.

Lead design and delivery of scalable, secure full-stack systems; mentor engineers; integrate AI-driven and agent-based workflows; ensure cloud-native, containerized deployments and secure SDLC practices.

Lead Software Engineer responsible for designing, developing, testing, and maintaining a distributed processing application using Python and Java. Collaborate with product owners, data coaches, analysts, DBAs, and Agile teams to meet backend/frontend requirements, implement cloud and big-data solutions (Spark/Hadoop), and ensure program standards and reliable delivery.

As a Senior Software Engineer (Backend), you will design and implement scalable applications, collaborate with agile teams, and mentor junior members while ensuring high code quality and performance.

The Staff Software Engineer will lead technical vision and execution, drive architectural decisions, mentor engineers, and ensure code quality and scalability.

Design and develop scalable backend services and APIs, building frontend applications, collaborating on features, and ensuring system reliability. Lead technical projects and improve engineering practices.

The Principal Software Engineer leads the design and development of scalable software solutions, mentors engineers, and drives architectural decisions while collaborating with cross-functional teams.

Build and operate full-stack, production-ready systems: design and ship AI-native mortgage automation, integrate third-party lending APIs, and architect scalable AWS infrastructure and job processing. Mentor engineers and ensure security, observability, and high reliability.

The Staff Software Engineer will lead technical projects, develop full-stack software, mentor teams, and drive product direction at Propel, focusing on impactful solutions.

As a Senior Software Engineer, you will design and optimize APIs, develop cloud functions, and collaborate with product teams to enhance user experiences at Speechify.

The Senior Software Engineer will build and maintain foundational services and SDKs, optimize functionality, and collaborate on product solutions using Kotlin.

Design, build, and maintain CRM+ features using C#, .NET, Vue, and SQL Server on Azure. Architect scalable services, use AI tools (Claude Code) in development, write well-tested code, mentor engineers, influence product and technical strategy, operate CI/CD, troubleshoot production issues, and collaborate cross-functionally.

Develop user interface components for ArcGIS Pro using C# and WPF, work in an agile team, and design software solutions for raster and imagery processing.

Design and build scalable web applications, collaborate on product direction, and implement complex systems using ML techniques, ensuring software quality.

Lead full lifecycle development of high-volume enterprise web applications using C#/.NET and AngularJS. Contribute to architecture and design, develop and test scalable solutions, troubleshoot production issues, mentor developers, and collaborate with analysts and business stakeholders in an Agile/Scrum environment.

Lead design and delivery of cloud-native .NET services for a high-throughput trading platform. Own end-to-end systems, drive architecture and reliability, mentor engineers, participate in on-call and incident response, and occasionally contribute to React/TypeScript frontend work while establishing engineering standards and observability.

The Senior Software Engineer will enhance patient experiences by developing modern software for doctor's offices, contributing to product features, and participating in client feedback.

The Staff Software Engineer will upgrade patient experience by developing features for a healthcare software platform, leading the product development throughout the process.

As a Senior Software Engineer, you will develop efficient systems to enhance healthcare delivery and collaborate with various teams to innovate features for patient care tools.

Design and build core systems for a new application using Solana's infrastructure. Focus on low-latency, reliable services, and implement security measures.

Lead the development of Runware's serverless platform by building core systems for AI workload management and providing technical guidance to the team.

The Senior Software Engineer will design and implement systems for AI integration, build scalable backend services, and mentor team members, ensuring high-quality systems that meet user needs.

As a Junior Software Engineer, you will develop applications, participate in a team environment, and leverage software development for better results.