Staff Software Engineer - Experience

Posted 8 Hours Ago
2 Locations
Remote or Hybrid
173K-235K Annually
Expert/Leader
Healthtech • Biotech
The Role
Sets technical direction for Helix’s Experience platform and broader engineering organization. Designs and implements distributed, full-stack genomic software systems focused on patient and provider experiences. Leads complex projects from scoping through production, advances AI-assisted engineering practices, establishes quality and delivery standards, mentors technical leaders, and drives cross-functional collaboration with product, design, research, scientific, and business teams.
Summary Generated by Built In
Who We Are & What We Do 
At Helix, our mission is simple: to help everyone improve their lives through their DNA.

Ready to make a real-world impact with your skills? At Helix, we're transforming healthcare by making genomics a standard of care. We partner with health systems and life science companies to accelerate the integration of genomic data into clinical practice. Join us in building a future where healthcare is personalized, proactive, and powered by genomics. 

What is special about this role?
The Helix Experience Team builds the software platform and user experiences that guide patients and providers through their entire genetics journey, from enrollment through results delivery. As a Staff Software Engineer, you will set the technical direction for this platform and shape engineering standards across the organization.

As a Staff Software Engineer - Experience, you will:
  • Guide and define the strategic technical direction for the Experience platform and wider Engineering organization.
  • Shape how Helix Engineering utilizes AI and advance our AI development best practices.
  • Direct AI agents to automate entire engineering workflows, including codifying our prompt libraries and context frameworks.
  • Design, architect, and implement software systems for our genomic applications and services, with a focus on the patient and provider experience.
  • Drive complex, ambiguous projects from scoping to production with autonomy, owning the design, architecture and implementation strategy. 
  • Collaborate and lead cross-functional work with product managers, designers, user experience researchers, scientists, and our business leaders to drive meaningful outcomes to the business.
  • Shape the engineering standards, delivery practices, and quality bars within all of Engineering.
  • Serve as a dedicated technical mentor, helping grow our next generation of technical leaders.
  • Champion durable solutions that eliminate entire categories of technical debt and raise reliability.

About you:
  • 10+ years of equivalent professional experience as a Software Engineer, with a track record of impact at scale.
  • A strong product engineering mindset, with technical decisions anchored in customer and business outcomes.
  • Operates with a high degree of autonomy, identifies problems before they're escalated and drives them to resolution proactively.
  • Experience implementing and a passion for driving AI adoption in engineering workflows, with a proven ability to build automated safeguards and evaluations that validate AI-generated code at scale.
  • Proficiency with distributed systems built on cloud infrastructure such as AWS, GCP, or Azure.
  • Deep full-stack expertise, proficient in a backend language such as Go, Java, Python, Scala, or Rust.
  • Familiarity and experience developing and maintaining SPA’s on frameworks such as React, Next.js, Vue.js or similar using TypeScript/JavaScript.
  • A track record of raising the technical standards and practices of engineers beyond your immediate team or department.
  • Adaptable in a fast-paced startup environment where priorities may change quickly and frequently.

Pluses:
  • Bachelor’s or Master’s degree in Computer Science or a related field.
  • Familiarity with regulated software systems in any industry, such as HIPAA, ISO, or FDA.
  • Experience designing and architecting event-driven architectures.
  • Experience with AWS serverless infrastructure.
  • Experience in the life sciences, healthcare, or genomics domain.

Expected Interview Process:
1) Initial Screen 2) Technical Interviews 3) Leadership Interviews 4) Offer 

Expected Pay For This Role:
There are 3 distinct parts to your Helix offer: 1) Base Salary 2) Annual Bonus 3) Equity 
  • Expected Helix Base:
    • US: $173,000 - $234,500 USD
    • CA: $173,000 - $218,000 CAD
  • Expected Helix Discretionary Annual Bonus: 15% of your annual salary
  • Equity: We offer generous equity at Helix. If you receive a Helix offer your recruiter will book dedicated time with you to educate you on our equity model.

Aside from working alongside brilliant, dedicated, passionate, down-to-earth, curious, warm, and thoughtful people, we also provide great benefits:
  • Comprehensive Health Insurance with Date of Hire eligibility 
    • Above average employer paid premium coverage 
  • 12 weeks Helix Paid Parental Leave option 
  • 401(k) with employer matching of up to 3% and 100% Vesting on the Date of Hire
  • Comprehensive Well-Being Benefits 
  • Flexible PTO
  • Remote options for many roles and a home office stipend 

What To Expect During Your First 90 days:
  • First 5 days: You’ll spend time learning the Helix way, completing training and onboarding for your roles, and getting introduced to your team and relevant stakeholders. You’ll also gain a deeper understanding of our customers, our products, the impact we make in the lives of our communities, and how to thrive at Helix through participation in Helix U.  
  • Day 5 - 30: You’ll spend time contributing to projects, deeply familiarizing yourself with team and company processes, and developing a deeper understanding of Helix’s products, services and capabilities. 
  • Day 30 - 90: You’ll build your OKRs with your manager, start to take ownership of projects and initiatives on your team, and begin to demonstrate your impact on the Helix mission.

To learn how Helix collects, uses, and protects your personal information during the recruitment process, please review our Privacy Notice.

Helix is proud to be an equal opportunity employer, and committed to providing employment opportunities regardless of race, religious creed, color, national origin, ancestry, physical disability, mental disability, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, pregnancy, childbirth and breastfeeding, age, sexual orientation, military or veteran status, or any other protected classification, in accordance with applicable federal, state, and local laws.

 #LI-Remote
Compensation
The base pay range for this role is $173,000 – $234,500 per year.

Skills Required

  • 10+ years of equivalent professional experience as a Software Engineer
  • Track record of impact at scale
  • Strong product engineering mindset focused on customer and business outcomes
  • Ability to operate autonomously and proactively resolve problems
  • Experience implementing AI adoption in engineering workflows
  • Ability to build automated safeguards and evaluations for AI-generated code at scale
  • Proficiency with distributed systems on cloud infrastructure such as AWS, GCP, or Azure
  • Deep full-stack expertise
  • Proficiency in a backend language such as Go, Java, Python, Scala, or Rust
  • Experience developing and maintaining single-page applications using React, Next.js, Vue.js, or similar frameworks
  • Proficiency with TypeScript or JavaScript
  • Track record of raising technical standards beyond an immediate team or department
  • Adaptability in a fast-paced startup environment
  • Bachelor’s or Master’s degree in Computer Science or a related field
  • Familiarity with regulated software systems, including HIPAA, ISO, or FDA environments
  • Experience designing and architecting event-driven architectures
  • Experience with AWS serverless infrastructure
  • Experience in life sciences, healthcare, or genomics

Helix Compensation & Benefits Highlights

The following summarizes recurring compensation and benefits themes identified from responses generated by popular LLMs to common candidate questions about Helix and has not been reviewed or approved by Helix.

  • Leave & Time Off Breadth Feedback suggests generous PTO, flexible time away, unlimited vacation, paid sick days, and paid parental leave support work–life balance. These policies are frequently highlighted alongside flexible scheduling.
  • Healthcare Strength Feedback suggests medical, dental, and vision coverage are complemented by a wellness program. Access to health-focused initiatives contributes to a comprehensive core benefits package.
  • Wellbeing & Lifestyle Benefits Feedback suggests commuter benefits, free daily meals, and onsite parking enhance day‑to‑day experience. Such perks, combined with flexible work arrangements, add lifestyle value beyond base pay.

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The Company
HQ: San Mateo, CA
200 Employees
Year Founded: 2015

What We Do

Helix is a rapidly growing startup focused on personal genomics. Helix has a simple but powerful mission: to empower every person to improve their life through DNA. We’re creating an ecosystem where people can explore diverse and uniquely personalized applications provided by high-quality partners.

Why Work With Us

We are collaborators—scientists, engineers, designers, marketers, and more—working across four offices to solve complex challenges locked within the human genome. We are biased toward action as we strive to uphold integrity in sequencing, science, and communication. At Helix, transparency, collaboration, and empowerment drive us in all that we do.

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