Top Remote Python Jobs in San Luis Obispo, CA

4 Days AgoSaved
Remote
Remote San Luis Obispo, CA
120K-140K Annually
Senior level
120K-140K Annually
Senior level
Artificial Intelligence • Big Data • Cloud • Information Technology • Machine Learning
Design and build full-stack applications that expose AI/ML insights. Develop backend services in Python, RESTful APIs, and containerized microservices. Build high-performance front-end interfaces with React/Vue/Angular. Implement cloud-native solutions on Google Cloud or Azure, manage relational and NoSQL databases, apply testing and CI/CD, and participate in Agile development and architecture sessions.
Top Skills: AngularAzureCi/CdDockerGCPJavaScriptKubernetesMongoDBMySQLPostgresPythonReactRestful ApisSQL ServerTypescriptVue
Reposted 6 Days AgoSaved
Remote or Hybrid
Remote San Luis Obispo, CA
Senior level
Senior level
Digital Media • Social Media • Software • Design
Design, develop, and maintain scalable Python applications; collaborate with cross-functional teams to deliver features; ensure performance and quality; identify and fix bugs; maintain code quality and automation; lead and mentor team members using agile practices.
Top Skills: Python
Reposted 6 Days AgoSaved
In-Office or Remote
Remote San Luis Obispo, CA
Mid level
Mid level
Healthtech
Own end-to-end product features for a SaaS platform serving HR, therapists, and employees. Build, scale, and evolve frontend and backend components, lead architecture and standards, collaborate with design and product, and incorporate customer feedback and QA. Work in an early-stage startup environment with product-focused ownership.
Top Skills: Next.JsPythonReact
Reposted 6 Days AgoSaved
In-Office or Remote
Remote San Luis Obispo, CA
Senior level
Senior level
Agency • Information Technology
Design, build, test, and maintain backend applications using FastAPI and SQLAlchemy. Implement database schemas, integrate front-end components, optimize for performance and scalability, debug issues, participate in code reviews, and collaborate on feature design. Maintain clean, testable code and stay current with best practices.
Top Skills: FastapiGitMySQLOraclePytestPythonSQLSqlalchemy
Reposted 8 Days AgoSaved
Remote
Remote San Luis Obispo, CA
Expert/Leader
Expert/Leader
Artificial Intelligence • Information Technology • Machine Learning • Software • Virtual Reality • Analytics
Nagarro seeks an Associate Principal Engineer with extensive IT experience in Python to drive strategic value and innovation in product engineering.
Top Skills: Python
Reposted 9 Days AgoSaved
Remote
Remote San Luis Obispo, CA
200K-225K Annually
Senior level
200K-225K Annually
Senior level
Artificial Intelligence • eCommerce • Software
Design and build backend systems and APIs for AI-driven products, ensuring scalability, reliability, and integration of ML models while collaborating with engineering and product teams.
Top Skills: APIsAWSAzureDockerGCPKubernetesLlmsMachine LearningNoSQLPythonSQL
Reposted 9 Days AgoSaved
Remote
Remote San Luis Obispo, CA
165K-215K Annually
Senior level
165K-215K Annually
Senior level
Legal Tech • Software
Design and implement durable, fault-tolerant AI orchestration and backend systems using Temporal and agentic ReAct patterns. Deliver features end-to-end with testing, CI/CD, monitoring, and observability; mentor engineers and collaborate with cross-functional teams to translate legal workflows into reliable AI-powered features.
Top Skills: Async/AwaitClaude (Llm)Event-Driven ArchitectureFastapiGitlab Ci/CdMessage QueuesNew Relic ApmOctopus DeployPlaywrightPydantic V2Pydantic-AiPytestPython 3.12+ReactStructlogSyrupyTemporal
Reposted 12 Days AgoSaved
Remote
Remote San Luis Obispo, CA
100K-200K Annually
Senior level
100K-200K Annually
Senior level
Artificial Intelligence • HR Tech • Information Technology • Software
As a Founding Staff Software Engineer, you will lead the design and development of robust backend systems and APIs, optimize large-scale data workflows, and mentor a growing engineering team.
Top Skills: AWSCeleryFastapiOpensearchPostgresPythonRedisTemporal
Reposted 13 Days AgoSaved
Remote
Remote San Luis Obispo, CA
Mid level
Mid level
Artificial Intelligence
Join Cerebras Systems to optimize and develop frontend compiler infrastructure for PyTorch models on their unique wafer-scale AI platform, focusing on model representation and optimization.
Top Skills: C++FxHuggingface TransformersLlvmMlirPythonPyTorchTorchdynamoTorchscript
14 Days AgoSaved
In-Office or Remote
Remote San Luis Obispo, CA
150K-200K Annually
Mid level
150K-200K Annually
Mid level
Artificial Intelligence • Food • Software • Hospitality
Build and maintain Python backend services and serverless architectures for a restaurant operations platform. Ship end-to-end features, design robust systems, and help define product roadmap. Implement CI/CD and productionization, collaborate with product and GTM teams, and contribute to team culture and technical execution.
Top Skills: Aws LambdaAws ServerlessAws Step FunctionsCi/CdGoJavaJavaScriptPythonReactTypescript
Reposted 14 Days AgoSaved
Remote
Remote San Luis Obispo, CA
125K-200K Annually
Senior level
125K-200K Annually
Senior level
Software • Cybersecurity
The Forward Deployed Engineer will serve as a technical bridge between clients and engineering teams, writing custom code and integrations, while ensuring customer success with Socket's security platform through strong relationships and expert technical guidance.
Top Skills: Automation ScriptsCi/CdDevOpsPythonSastWebhook Implementations
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Reposted 14 Days AgoSaved
Remote
Remote San Luis Obispo, CA
Senior level
Senior level
Artificial Intelligence • Logistics • Software • Transportation
Design, develop, deploy, monitor, and support APIs and system integrations (Salesforce, REST, third-party). Work directly with clients to gather requirements, troubleshoot and optimize integrations, operate solutions in AWS, collaborate with teams, and mentor junior developers.
Top Skills: Aws Api GatewayAws EcsAws LambdaAws RdsPythonRest ApiSalesforceSnsSqsTerraform
Reposted 14 Days AgoSaved
Remote
Remote San Luis Obispo, CA
Senior level
Senior level
Information Technology • Logistics • Transportation • Consulting
Build and ship full‑stack features for transportation management and other client products. Design and implement APIs and UIs, collaborate with product and design, own delivery, write modular testable code, troubleshoot and iterate quickly, and mentor peers.
Top Skills: .NetC#Ci/CdDevOpsDockerElectronFastapiGraphQLJavaJavaScriptLlmsLookmlMlMongoDBMySQLNode.jsPythonReact NativeReactRestSpringTypescriptVue
Reposted 17 Days AgoSaved
Remote
Remote San Luis Obispo, CA
130K-170K Annually
Mid level
130K-170K Annually
Mid level
eCommerce
As a Software Engineer III, you will design, develop, and maintain high-quality software solutions, collaborating with cross-functional teams to ensure scalability and performance.
Top Skills: AngularConfluenceDjangoJIRANode.jsNoSQLPythonReactSpringSQL
Reposted 17 Days AgoSaved
Remote
Remote San Luis Obispo, CA
Senior level
Senior level
Automotive
The Senior Software Engineer will build a large-scale data ingestion and classification system using web scraping, data processing, and search technologies, overseeing data extraction from various sources and developing search capabilities.
Top Skills: AirflowAWSElasticsearchKubernetesOcrOpensearchPythonScrapySpark
18 Days AgoSaved
Remote
Remote San Luis Obispo, CA
141K-208K Annually
Senior level
141K-208K Annually
Senior level
Database • Analytics
Own and evolve ClickHouse's Python connector and SDKs; build and maintain integrations with orchestration and transformation tools; design AI/LLM integration patterns (RAG, embeddings, feature stores); engage with open-source community; collaborate with Product and Cloud teams to prioritize and ship production-grade data integrations.
Top Skills: Apache AirflowApache FlinkSparkAsyncClickhouseDagsterDbtFivetranKafka ConnectLangchainLlamaindexMultiprocessingN8NNumpyPandasPrefectPydanticPythonSQLSqlmeshThreading
Reposted 18 Days AgoSaved
Remote
Remote San Luis Obispo, CA
Senior level
Senior level
Travel
As a Staff Software Engineer, you’ll lead the design and reliability of Duetto's data lakehouse, evolving data systems using Python and AWS, ensuring data quality, and implementing AI-driven solutions.
Top Skills: AirflowAWSDatadogDockerGithub ActionsGlueIcebergPysparkPythonSagemakerSentrySumo LogicTerraform
Reposted 20 Days AgoSaved
Remote
Remote San Luis Obispo, CA
139K-203K Annually
Senior level
139K-203K Annually
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Marketing Tech • Software • Biotech • Design
Develop and maintain backend solutions, ensuring performance, security, and regulatory compliance, while collaborating in cross-functional teams.
Top Skills: AWSFastapiPython
Reposted 20 Days AgoSaved
Remote
Remote San Luis Obispo, CA
Mid level
Mid level
Agency • Artificial Intelligence • Blockchain • Web3
Build and maintain API services for a decentralized exchange, design and implement trade routing logic for optimized cross-chain swaps, integrate features with cross-functional teams, monitor system performance and reliability, and troubleshoot trade execution and API issues.
Top Skills: Node.jsPythonRedisSQL
Reposted 21 Days AgoSaved
Remote
Remote San Luis Obispo, CA
Senior level
Senior level
Information Technology • Consulting
Design and build applications using Python, manage component design, optimize performance, and collaborate with clients on innovative products.
Top Skills: Ai ToolsCi/CdGitGoKubernetesPythonReact
Reposted 24 Days AgoSaved
In-Office or Remote
Remote San Luis Obispo, CA
Mid level
Mid level
Cloud • Software
We are seeking a software engineer to build and validate resilient distributed systems, enhance CI pipelines, and improve testing strategies for cloud applications.
Top Skills: AWSCircleCIGithub CiGoJenkinsKubernetesOpenstackPythonTerraform
Reposted 24 Days AgoSaved
In-Office or Remote
Remote San Luis Obispo, CA
135K-155K Annually
Senior level
135K-155K Annually
Senior level
Machine Learning • Other
The Backend Software Engineer will develop and maintain backend systems for data processing related to coffee farming, utilizing Python and PostgreSQL. Responsibilities include feature development, problem-solving, and adapting systems to regulatory changes while ensuring system resilience.
Top Skills: AWSCi/CdDockerPostgresPostgresql/PostgisPythonTerraform
Reposted 25 Days AgoSaved
Remote
Remote San Luis Obispo, CA
Senior level
Senior level
Software
Lead the design and development of scalable Python backend services and APIs on AWS, mentor engineers, and manage PostgreSQL databases in a healthcare technology environment.
Top Skills: Api GatewayAWSBitbucketDockerGitJIRAKubernetesLambdaOauth 2PostgresPythonRest ApiSlackTeams
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