Top Remote Python Jobs in San Diego, CA

Lead enterprise EKS consolidation and architecture: assess 20+ clusters, design a multi-tenant golden-cluster standard, define CNI/service-mesh strategy, enforce zero-trust IAM, implement IaC with Terraform, enable resilient ingress and storage patterns, validate via pilot Python workloads, and define lifecycle, DR (Velero/S3), and CI/CD (GitHub Actions runners) governance.

Own architecture, development, and reliability of ecommerce web applications (Symfony storefront and Laravel back-office). Lead front-end JavaScript/CSS direction, optimize SQL schemas/queries, improve observability and incident response, reduce legacy technical debt, establish AI-assisted development workflows, mentor engineers, and drive end-to-end delivery of scalable customer-facing features.

Build and ship full‑stack product features on a Python/Flask backend and React frontend. Design REST/GraphQL APIs, work with SQLAlchemy and relational data models, integrate LLM/AI features, use async task queues (Celery), and collaborate with product, design, and engineers to deliver reliable, well-tested features end-to-end.

Design, build, and architect stablecoin and crypto infrastructure; integrate DEXs, DeFi protocols, and wallet providers; develop smart contract interactions; expand crypto product functionality and asset selection; collaborate cross-functionally; establish crypto development standards and ensure security and reliability for large-scale user experiences.

Technical lead for public-facing gRPC APIs and SDKs powering provider search, ranking, and dynamic copay lookups. Own API design, versioning, ranking/steerage logic, and reliability at scale. Write and review code and designs, mentor engineers, drive technical direction, partner with product and partner engineering, and support production operations and scaling decisions.

Design, build, and operate enterprise-scale multi-cloud infrastructure (primarily Azure, also AWS). Implement IaC (Terraform, ARM/Bicep, CloudFormation), CI/CD (GitHub Actions), monitoring, security/compliance, FinOps, automation scripting, and platform engineering to support reliability, performance, and AI/ML workloads.

Support environmental and laboratory testing of sensor systems: create qualification test procedures/reports to MIL-STD/RTCA standards, perform test setups, develop/maintain automated test software (LabVIEW/Python), integrate lab equipment, coordinate with program managers, customers, and cross-functional teams, and occasionally travel to external test labs.

The Lead Technology Engineer will lead IT systems implementation, ensure network security, manage integrations, and enhance operational efficiency through automation.

Lead backend development and operate services end-to-end: design, implement, deploy, monitor, and troubleshoot cloud-based back-end systems. Participate in on-call rotation, collaborate with frontend, CloudEng, and product teams, conduct code and security/privacy reviews, and mentor junior engineers.

Lead and grow a DevOps team responsible for AWS/Azure infrastructure, CI/CD, reliability, observability, incident response, and FinOps. Set technical direction for IaC, pipelines, and service management while partnering with Product, Engineering, and Security and participating in on-call rotation.

Build full‑stack web features from zero to one, integrate with third‑party APIs, design and manage state machines for financial workflows, own features through launch and post‑launch customer iteration, and maintain high code quality and accountability.

Lead end-to-end delivery of 2-3 large SaaS customer implementations, triage cross-functional issues, build repeatable tooling and processes, mentor teammates, and feed implementation learnings into Product and Engineering while advancing AI-enabled workflows.

Senior iOS developer responsible for implementing native iOS features, improving user experience, participating in agile squads, conducting code reviews, troubleshooting customer issues, and helping modernize backend services on AWS. Collaborates with product and UI teams and documents technical knowledge while following best practices.

Design and implement durable, fault-tolerant AI orchestration and backend systems using Temporal and agentic ReAct patterns. Deliver features end-to-end with testing, CI/CD, monitoring, and observability; mentor engineers and collaborate with cross-functional teams to translate legal workflows into reliable AI-powered features.

Develop, test, and maintain production-quality C++ software implementing Government Reference Architectures for mission-critical defense systems. Translate MBSE (SysML/Cameo) artifacts into interoperable components, implement APIs/ICDs, integrate distributed messaging frameworks (ActiveMQ/DDS/ZeroMQ), and maintain CI/CD, automated testing, containerized builds, and static analysis. Collaborate with systems engineers, architects, autonomy engineers, and government stakeholders to validate interoperability and performance.

Improve, modernize, and sustain complex, distributed defense software by debugging production issues, performing root-cause analysis, refactoring legacy code, reducing technical debt, enhancing CI/CD and automated testing, and collaborating with engineers, architects, and government stakeholders to maintain performance, interoperability, and delivery schedules.

Develop systems software to parse, reverse-engineer, and deterministically generate complex engineering data. Build tooling for schema translation, compiler/transpiler solutions, reproducible CI/CD pipelines, and automated document generation. Collaborate with multidisciplinary teams, support verification/validation, and apply MBSE concepts for engineering integration.

Build and maintain Python tools for web scraping, automation, integrations (Airbnb, marketplaces), ad automation, chatbots (Chatwoot), workflow automation (Spiffworkflow), automated tests, and data analysis.

Work with senior engineers to develop, test, and maintain full-stack web applications. Build front-end interfaces, implement back-end APIs, write clean code, assist with testing and code reviews, participate in Agile ceremonies, and continuously learn new tools and best practices.

Design, build, and maintain scalable full-stack web applications. Implement backend APIs and responsive frontends, deploy to cloud, ensure security/performance, write tests, debug issues, participate in reviews, and mentor junior developers.

Lead cloud-native platform engineering initiatives: migrate Jenkins pipelines to Harness, move GCVE/on‑prem workloads to GKE, implement GitOps, IaC (Terraform/Ansible), enforce cloud governance and security, build observability and scalable GKE infrastructure, and coach teams on agile and best practices to improve developer productivity.

Build and ship end-to-end product features, debug and resolve production issues, partner with Product on UX and direction, use AI heavily for development and prototyping, and iterate quickly across the stack to improve quality and speed.

Lead technical execution across backend, frontend, mobile, AI, and data. Translate ambiguous product goals into technical plans, unblock hard engineering problems, coordinate cross-domain work, raise engineering quality, define hiring needs and technical evaluation standards, and build internal AI workflows to foster an AI-native engineering culture.

Build and enhance full-stack web applications and APIs using React/TypeScript and Python. Work with PostgreSQL, DynamoDB, AWS, event-driven architectures, CI/CD, and AI-assisted development tools to prototype and improve AI-native engineering workflows.

Lead the design and optimization of scalable data ingestion pipelines, develop reusable ETL components, and mentor junior engineers while leveraging expertise in Python and AWS for the Arine platform.