Top Remote Python Jobs in San Diego, CA

Senior DevOps Engineer/Consultant role focusing on DevOps transformations, coaching clients, managing infrastructure, and automating software delivery processes.

The Senior Research Engineer designs and builds data-intensive systems and tooling, mentoring the team and enhancing project efficiency across research and civic technology.

As a Staff SDET, you'll design and implement automated integration testing strategies for our data platform, ensuring data quality and influencing overall testing standards while mentoring other engineers.

The Software Engineer will build scalable backend systems, integrate third party software, and optimize performance, aiming to enhance efficiency in the moving industry.

The Staff Machine Learning Engineer will develop and maintain MLOps tools, optimize model performance, and collaborate on ML system architecture with a focus on enhancing developer experience.

The role involves leading technical teams to develop high-quality software, mentoring engineers, and contributing to open source projects. Responsibilities include planning, execution, and enhancing the Linux user experience across various teams and technologies.

Design and architect scalable backend services, develop robust governance systems, build SaaS solutions, and mentor junior engineers to enhance IoT platform capabilities.

The role involves developing cloud-native database solutions, particularly focusing on autoscaling functionality, and collaborating with various teams to enhance cloud infrastructure and performance.

Lead the design and optimization of scalable data ingestion pipelines, develop reusable ETL components, and mentor junior engineers while leveraging expertise in Python and AWS for the Arine platform.

Design, develop, and maintain scalable software solutions, collaborating with cross-functional teams and mentoring junior developers to enhance Arine's web applications and APIs.

Lead and mentor engineering teams to deliver high-quality, AI-driven software, ensuring accountability and continuous improvement in development processes.

The Research Engineer will develop automated security analysis solutions for mobile applications and conduct research to identify security issues.

Lead development and maintenance of large-scale distributed systems and software platforms; design, test, deploy, and optimize applications used by physicians and patients; manage EDI analysts; collaborate with cross-functional teams to deliver technical solutions, monitor reliability, and drive system scalability and performance.

Perform manual and automated testing across web, mobile, APIs, backend services, and blockchain integrations. Build and maintain Python-based test frameworks, investigate issues across distributed systems, analyze logs/metrics/network traffic, contribute to release validation and automation, and collaborate with product, engineering, and DevOps. Use AI tools to accelerate testing, support incident analysis, and proactively improve testing coverage and product reliability.

Lead design, build, and maintenance of scalable, secure blockchain participation and custody infrastructure. Improve automation, monitoring, incident response, and observability; debug distributed protocols; inform leadership strategy; scope product opportunities; and support on-call reliability and deployment automation.

Build and maintain end-to-end product features across frontend, backend, and databases. Design APIs, authentication, data models, integrations, and AI-assisted workflows. Ship production-ready SaaS components, debug across the stack, improve reliability and performance, and collaborate on product and architecture decisions in an early-stage startup.

Design, implement, and manage scalable AWS infrastructure (EC2, S3, RDS, VPC, EKS) using IaC (Terraform/CloudFormation), automation, containerization (Docker, Kubernetes), and CI/CD (GitHub Actions). Enforce cloud security (IAM, encryption, network segmentation), monitor and optimize performance/cost, troubleshoot infrastructure and deployment issues, and collaborate with development teams. Support VA project requirements, undergo background checks, and complete fingerprinting.

Develop and maintain high-performance, scalable web applications using React/Next.js and TypeScript. Collaborate across design, product, and engineering, provide technical feedback, use GraphQL/REST, manage complex client state, and support backend Python and AWS infrastructure. Emphasize scalability, performance, security, and CI/CD containerized deployments while adopting AI-driven automation and agentic workflows.

Lead a hands-on engineering team building shared backend and cloud platform services. Architect, code, and ship high-volume REST APIs and reusable libraries, drive secure SDLC and CI/CD, mentor engineers, and promote AI-augmented delivery practices.

Build information-rich legal data visualizations using JavaScript, React, D3, and SVG. Use Python and Pyramid to retrieve and prepare data. Design for accessibility and usability, integrate new legal content with subject-matter experts, collaborate with frontend/back-end and NLP engineers, and participate in code reviews. Provide a portfolio of reviewable code samples.

Lead design, reliability, and evolution of hybrid-cloud and workplace infrastructure. Own domain architecture, drive migrations and reliability improvements, define SLIs/SLOs, automate with IaC, mentor engineers, collaborate across IT/SRE/Security, and maintain operational documentation and runbooks.

Lead design, reliability, and evolution of hybrid-cloud and workplace infrastructure. Architect scalable systems, drive complex migrations and performance improvements, improve reliability through monitoring and automation, collaborate across teams, mentor engineers, and maintain documentation and runbooks.

Lead design and delivery of end-to-end integrations between C2, communications, and commercial systems. Build backend services, APIs, SDKs, and front-end interfaces. Mentor engineers, shape integration architecture, engage open-source developer community, and own implementation, deployment, validation, and support for production integration solutions.

Owner of full-stack features and platform reliability: build scalable web applications, optimize PostgreSQL performance, maintain asynchronous infrastructure (Celery), migrate frontend to server-side HTMX, ship revenue-driving features, ensure observability and SLO-driven reliability, collaborate cross-functionally, write testable code, and participate in architecture and code reviews.

Lead enterprise cloud architecture engagements, define target-state AWS architecture and roadmaps, establish standards and governance, design scalable multi-account and hybrid infrastructures, implement IaC (Terraform/CloudFormation), build automation and CI/CD pipelines, mentor client teams, optimize cost/performance/security, and lead architecture reviews and workshops.