Top Remote Python Jobs in San Diego, CA

One Month AgoSaved
Remote
Remote San Diego, CA
185K-215K Annually
Senior level
185K-215K Annually
Senior level
Digital Media • Professional Services • Consulting • Financial Services
Leads and mentors an engineering team building scalable web applications for fintech and media products. Responsibilities include setting technical architecture, guiding engineering decisions, partnering with product and design stakeholders, maintaining modern web applications, improving reliability and performance, supporting delivery planning, and adopting AI-assisted development and automation. The role combines hands-on software engineering, people management, technical strategy, and cross-functional collaboration.
Top Skills: Apollo ClientAWSCi/CdDjangoDockerGraphQLJIRANext.JsPythonReactReduxRest ApisSlackTypescriptZoom
One Month AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Financial Services • Metaverse
Administer and optimize Azure Databricks environments across development, staging, and production. Manage workspaces, clusters, jobs, SQL warehouses, Unity Catalog, permissions, identity integrations, security controls, monitoring, troubleshooting, disaster recovery, and cost efficiency. Partner with data engineering, cybersecurity, compliance, and governance teams to maintain reliable, secure, auditable, and well-documented data analytics infrastructure in a regulated financial services environment.
Top Skills: SparkAzure DatabricksAzure Key VaultAzure MonitorAzure StorageDatabricks CliDelta LakeLog AnalyticsMicrosoft Entra IdPowershellPythonRest ApisScimSQLTerraformUnity Catalog
One Month AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Cryptocurrency
Build and operate Conduit's control plane services for provisioning, updating, repairing, and retiring customer infrastructure. Design schema-driven lifecycle systems, usage metering, APIs, contracts, internal tooling, and integrations with billing and partner systems. Ensure reliability through reconciliation, event-driven workflows, idempotency, retries, and eventual consistency. Own cross-team interfaces, improve maintainability, participate in on-call, and debug complex production issues across networking, performance, data integrity, and security boundaries.
Top Skills: ArgocdCueGcp Pub/SubGoGoogle Cloud PlatformGoogle Cloud StorageGrpcKubernetesPostgresProtocol BuffersPythonRedisRiverYaml
One Month AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
AdTech • Fintech • Gaming • Mobile • Software • App development
Own and operate a globally distributed VPN network, AWS control plane, backend infrastructure, and infrastructure-as-code tooling. Improve reliability, security, automation, observability, CI/CD, deployment safety, and cost efficiency across multiple providers. Troubleshoot production incidents, participate in 24/7 on-call, manage networking and VPN technologies, and replace manual operational processes with tested automation. Partner with engineering and product teams while ensuring high uptime, connection success, performance, and compliance.
Top Skills: AnsibleAWSAws Secrets ManagerAws SsmBashBitriseCloudflareCloudwatchDatadogDigitaloceanDnsDockerEc2FastlaneGithub ActionsGoGrafanaGvisor NetstackHetznerIamIkev2/IpsecIptablesKubernetesLambdaLinodeLinuxLwipMongoDBNftablesNode.jsNomadObfs4OpenvpnPackerPostgresPrometheusPythonRdsRedisRoute 53S3ShadowsocksTerraformTlsV2RayVaultVpcVultrWireguardWireguard-GoXcode CloudXray
One Month AgoSaved
Remote or Hybrid
Remote San Diego, CA
79K-105K Annually
Mid level
79K-105K Annually
Mid level
Healthtech
Leads complex healthcare IT implementations for Intelerad’s InteleShare platform. Designs and deploys HL7/DICOM integrations, configures and validates enterprise systems, resolves advanced application and infrastructure issues, supports go-lives, delivers end-user training, and documents workflows and architecture changes. Partners with project managers, clients, and vendors to meet integration milestones. Also supports custom reports, SQL queries, migrations, workflow improvements, and post-implementation reviews. Travel up to 10% may be required.
Top Skills: Api ArchitectureAWSAws SagemakerDicomGitHl7InteleshareJSONLinuxMicrosoft Sql ServerPostgresPythonSQLSybaseVisual Studio Code
One Month AgoSaved
Remote or Hybrid
Remote San Diego, CA
160K-180K Annually
Senior level
160K-180K Annually
Senior level
Healthtech • Software
Own production reliability across cloud environments by defining SLOs, SLIs, error budgets, observability practices, and actionable dashboards. Troubleshoot incidents, perform root cause analysis, manage capacity planning, and improve service performance and availability. Build automation to reduce toil, support release management, maintain runbooks, and collaborate with engineering teams on operational readiness. Manage tools including Datadog, Prometheus, and Grafana while advancing monitoring, logging, metrics, tracing, and reliability practices.
Top Skills: .NetArgoAWSDatadogGithub ActionsGitlabGoGrafanaHelmJavaJenkinsKargoKubernetesLinuxOpentelemetryPrometheusPythonSplunkWindows
One Month AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Artificial Intelligence • Cloud • Software
Leads large-scale cluster deployment from rack delivery through production acceptance, including network bring-up, cabling verification, GPU-fabric integration, validation, burn-in, and RCCL performance testing. Manages deployment engineers across concurrent builds, improves deployment velocity, establishes operational playbooks and acceptance gates, coordinates with data center teams and vendors, and drives defect resolution across network, cabling, and hardware partners.
Top Skills: AnsibleGpu ClustersNcclNetwork FabricsOptical NetworkingPythonRccl
One Month AgoSaved
Remote
Remote San Diego, CA
225K-275K Annually
Senior level
225K-275K Annually
Senior level
Healthtech
Lead a multi-team engineering organization responsible for delivery, technical quality, production reliability, security, privacy, and AI-native development practices. Build scalable teams and managers, establish cross-team delivery systems, partner with Product and Design, oversee observability and incident response, use engineering metrics to guide improvements, and shape hiring, leveling, and talent development.
Top Skills: Ai AgentsAWSAzureC#JavaPython
One Month AgoSaved
Remote
Remote San Diego, CA
180K-220K Annually
Senior level
180K-220K Annually
Senior level
Healthtech
Designs and operates secure, scalable Azure cloud infrastructure supporting AI initiatives. Builds Infrastructure as Code, CI/CD pipelines, self-service provisioning, containerized environments, observability, monitoring, and reliability practices. Establishes platform standards, evaluates emerging technologies, drives cross-team architecture decisions, mentors engineers, and ensures governance, security, compliance, data quality, and auditability. The role is fully remote with up to 10% travel.
Top Skills: AlertingAWSAzureBashCi/CdCloud InfrastructureDockerGithub ActionsGitlab CiGoIncident ResponseInfrastructure As CodeKubernetesMonitoringMulti-CloudObservabilityPulumiPythonTerraform
One Month AgoSaved
Remote
Remote San Diego, CA
Entry level
Entry level
Information Technology • Security • Software
Lead an engineering team building endpoint configuration management capabilities, including policies, baselines, drift detection, remediation, staged rollouts, reporting, and audit trails. Provide technical direction, manage delivery and capacity, guide architecture, coordinate with product and core engineering teams, and operate automated build, test, validation, and deployment pipelines. The role requires expertise in Node.js, JavaScript, TypeScript, Python, AWS, endpoint management, desired-state systems, intermittent connectivity, and safe configuration changes.
Top Skills: AWSCis BenchmarksJavaScriptNode.jsPowershellPythonSQLTypescriptWindows
One Month AgoSaved
Remote
Remote San Diego, CA
150K-200K Annually
Senior level
150K-200K Annually
Senior level
Artificial Intelligence • Cybersecurity • Quantum Computing • Defense
Build and maintain secure, full-stack cybersecurity and compliance applications for cloud and on-premise environments. Develop APIs, integrations, data ingestion and normalization, risk analytics, relationship models, role-based access, CI/CD pipelines, and containerized deployments. Support post-quantum cryptography and compliance workflows while troubleshooting production issues and applying DevSecOps practices. Collaborate across engineering, cloud, cybersecurity, and compliance teams in a highly regulated, ambiguous product environment.
Top Skills: Apache AgeCi/CdClaude CodeCursorDjangoDockerFedrampFismaGitGithub ActionsGithub CopilotGitlab CiGoInfrastructure As CodeJavaScriptKubernetesNeo4JNetworkxNist CsfNist RmfNist Sp 800-53Openai CodexPkiPostgresPythonRelational DatabasesRest ApisServicenowSIEMTenableTypescript
One Month AgoSaved
Remote
Remote San Diego, CA
130K-160K Annually
Senior level
130K-160K Annually
Senior level
Fintech • Financial Services
Design, implement, and maintain MEMX’s low-latency trading network infrastructure. Configure network devices using Ansible and Python, monitor alerts, resolve incidents, perform root-cause analysis, and support customer connectivity turn-ups and tickets. Analyze and validate new products, implement secure end-user solutions with security teams, and coordinate with data center and circuit providers. The role requires expertise in distributed systems, routing protocols, multicast, network operating systems, timing protocols, packet analysis, firewalls, and optical networking.
Top Skills: AnsibleArpBgpEosFirewallsIgmpiOSIp MulticastLinuxmacOSMlagNatNetwork TransceiversNtpOptical FiberPan-OsPimPim-BidirPim-SmPtpPythonTcpdumpWireshark
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One Month AgoSaved
Remote
Remote San Diego, CA
180K-225K Annually
Expert/Leader
180K-225K Annually
Expert/Leader
Real Estate • Travel • PropTech
Own Airbnb’s Workday integration architecture, technical strategy, and production reliability across global HR, payroll, benefits, and employee systems. Build complex Workday integrations, payroll interfaces, Extend applications, and AI-enabled MCP tooling. Establish security, observability, governance, deployment, and compliance standards while managing release cycles and technical debt. Serve as the technical authority, mentor engineers, lead architectural decisions, and partner with HR, security, privacy, finance, enterprise architecture, and vendors.
Top Skills: Agile/ScrumBoomiGitJavaJSONLlmsMcp ServersMulesoftNode.jsOauth 2.0PgpPythonRest ApisSAMLSftpSoapSQLTypescriptWorkatoWorkday Core ConnectorsWorkday Document TransformsWorkday EibsWorkday ExtendWorkday OrchestrateWorkday RaasWorkday StudioWorkday Web ServicesXMLXslt
One Month AgoSaved
Remote or Hybrid
Remote San Diego, CA
Entry level
Entry level
Software
Develop and prototype 5G network solutions, automate and improve software development tools and environments, and help design, build, and maintain development verification labs. The role requires programming across Python, JavaScript, Bash, C/C++, and Go, along with Git, Linux, debugging, and Agile/Scrum knowledge. Work supports Nokia’s satellite-based LTE and 5G networking products.
Top Skills: 5GAgileBashCC++CloudCore NetworksGitGoJavaScriptLinuxLtePythonRanScrum
One Month AgoSaved
Remote
Remote San Diego, CA
105K-120K Annually
Senior level
105K-120K Annually
Senior level
Information Technology • Software
Develop and maintain secure, highly available public and private cloud infrastructure using automation, Infrastructure as Code, Kubernetes, Puppet, and deployment pipelines. Responsibilities include cloud architecture, IAM, networking, scripting, containerization, monitoring, troubleshooting, disaster recovery, security collaboration, and on-call support. The role also mentors engineers, researches emerging technologies, and partners with DevOps and Basis teams to support cloud-based applications.
Top Skills: Amazon Web ServicesAnsibleBashDhcpDnsDockerGCPIcmpKubernetesLinuxAzureMicrosoft Sql ServerOpenstackPostgresPowershellPuppetPythonTcp/IpTerraformVlansVpcVpnVxlansWindows
One Month AgoSaved
Remote
Remote San Diego, CA
Expert/Leader
Expert/Leader
Fintech • Analytics • Financial Services
Lead and grow a backend and full-stack engineering team responsible for Tradeify’s live trading platform. Partner with Product and Engineering teams on platform integrations, architecture, delivery, code quality, CI/CD, reliability, observability, and incident response. Remain hands-on through code reviews, design guidance, and technical problem solving while managing performance, hiring, onboarding, and cross-functional communication.
Top Skills: AWSAzureC#ClickhouseDockerGCPGoKafkaKubernetesMongoDBMySQLNatsNext.JsNinjatraderNode.jsPostgresPulsarPythonReactRedisRest ApisTimescaledbTradovateVueWebsocket
One Month AgoSaved
Remote
Remote San Diego, CA
Entry level
Entry level
Fintech • Analytics • Financial Services
Lead the engineering team building Arcnine, Tradeify’s real-time trading platform from development through launch. Hire and develop engineers, guide architecture, partner with Product and Design, remain hands-on with code, establish quality and delivery practices, and own reliability, observability, and incident response. The role also contributes to company-wide engineering standards and communicates progress, risks, and needs to founders and cross-functional stakeholders.
Top Skills: AWSAzureC#Ci/CdClickhouseDockerGCPGoKafkaKubernetesMongoDBMySQLNatsNext.JsNode.jsPostgresPulsarPythonReactRedisRest ApisTimescaledbVueWebsockets
One Month AgoSaved
Remote
Remote San Diego, CA
100K-171K Annually
Senior level
100K-171K Annually
Senior level
Insurance
Designs, develops, tests, documents, and operates large-scale distributed software products for Allstate’s Enterprise Payments organization. Responsibilities include building Java and Spring Boot REST APIs, designing microservices, collaborating on system architecture, practicing paired programming and test-driven development, establishing CI/CD pipelines, improving performance, securing APIs, supporting production applications, and contributing to Agile planning, retrospectives, and knowledge sharing.
Top Skills: Api GatewaysArtifactoryCachingCloud ComputingContinuous DeliveryContinuous DeploymentContinuous IntegrationGitGradleJavaJenkinsKafkaMavenMicroservicesNpmOauthOpenapiOpenidOwaspPythonReactRest ApisRest-DocsSAMLSpring BootSQLSwaggerTest-Driven Development
One Month AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Artificial Intelligence • Big Data • Machine Learning • Software
Own the direction and execution of critical AI development products. Build AI-assisted annotation tools, data exploration and visualization interfaces, RLHF workflow products, large-scale data processing systems, and tools for communicating complex instructions. Make autonomous technical and product decisions, lead ambiguous projects, ship rapidly, and collaborate with engineering and research leaders to support AI training and evaluation.
Top Skills: PythonReactRuby On RailsTypescript
One Month AgoSaved
Remote
Remote San Diego, CA
Entry level
Entry level
Artificial Intelligence • Big Data • Machine Learning • Software
Build scalable data pipelines, automation workflows, internal tools, and AI-powered quality-control systems. Lead data collection projects for frontier AI labs, establish quality frameworks, improve customer support processes, and manage cross-functional execution. Collaborate with technical and non-technical stakeholders to solve ambiguous operational challenges and deliver datasets and systems that improve advanced AI models.
Top Skills: Python
One Month AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Artificial Intelligence • Big Data • Machine Learning • Software
Design and build core fullstack systems powering Surge’s AI platform. Own frontend product decisions, backend architecture, and high-impact workflows for data collection, labeling, and evaluation. Ship scalable, reliable, intuitive tools while making autonomous technical decisions, collaborating with engineering and machine learning leaders, and maintaining high standards for usability, performance, and maintainability.
Top Skills: PythonReactRuby On RailsTypescript
One Month AgoSaved
Remote
Remote San Diego, CA
160K-180K Annually
Senior level
160K-180K Annually
Senior level
Artificial Intelligence • Machine Learning • Software
Own enterprise deployments of Qodo’s Kubernetes-based platform in customer-managed AWS, GCP, and Azure environments. Install, configure, upgrade, troubleshoot, and optimize infrastructure, writing Python or Bash diagnostics and codifying repeatable processes with Terraform and Helm. Partner directly with customer engineering teams, resolve complex networking and access issues, maintain PostgreSQL and Redis infrastructure, and improve deployment reliability through automation and documentation.
Top Skills: AWSAzureBashDockerGCPHelmIamKubernetesLinuxPostgresPythonRedisTerraform
One Month AgoSaved
Remote
Remote San Diego, CA
Mid level
Mid level
Artificial Intelligence • Information Technology • Consulting
Forward Deployed Engineers embed with customers to identify operational problems, analyze imperfect data, rapidly prototype and deploy AI-powered solutions, and drive adoption. Responsibilities include building pipelines, models, dashboards, optimizers, agents, and operational applications; collaborating with stakeholders; training users; improving platform capabilities; and supporting follow-on customer opportunities. The role requires technical execution, product thinking, client partnership, commercial awareness, and significant travel.
Top Skills: Ai AgentsAPIsCloud EnvironmentsData PipelinesData VisualizationEnterprise Data ArchitecturesLlm ApplicationsMachine LearningOperations ResearchOptimizationPythonRapid Application FrameworksRetrieval SystemsSimulationSQLTypescript
Reposted 2 Months AgoSaved
Easy Apply
Remote
Remote San Diego, CA
Easy Apply
205K-240K Annually
Senior level
205K-240K Annually
Senior level
Healthtech • Insurance • Sales • Software
Lead full‑stack development and architecture for Spark’s broker platform. Deliver customer‑facing features, partner with product/design, mentor engineers, resolve technical debt, and set engineering standards while using AI developer tools.
Top Skills: AWSDjangoJavaScriptPythonReactVue
Reposted 2 Months AgoSaved
Easy Apply
Remote
Remote San Diego, CA
Easy Apply
169K-240K Annually
Senior level
169K-240K Annually
Senior level
Big Data • Fintech • Mobile • Payments • Financial Services
Responsible for leading a team of engineers, supporting product development, identifying technical issues, and ensuring high-quality code delivery in backend systems at scale.
Top Skills: AWSJavaScriptKotlinKubernetesMySQLPythonReact NativeSwiftTypescript
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