Top Remote Python Jobs in San Diego, CA

Reposted 8 Days AgoSaved
Remote
Remote San Diego, CA
120K-261K Annually
Senior level
120K-261K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Design, build, and operate infrastructure for Azure Red Hat OpenShift's Hosted Control Plane. Manage and automate hundreds of AKS clusters, automate regional buildouts and CI/CD, monitor and release microservices, improve product integration with AKS, and collaborate with Microsoft and Red Hat to ensure scalable, secure, and resilient cloud-native infrastructure.
Top Skills: AksAzureAzure DevopsBsdC#C++Ci/CdCloud NativeContainersGitGitlabGoJavaJavaScriptKubernetesLinuxMicroservicesOpenshiftPythonRed Hat OpenshiftRust
Reposted 8 Days AgoSaved
Remote
Remote San Diego, CA
140K-165K Annually
Senior level
140K-165K Annually
Senior level
eCommerce
Design, build, and optimize AWS/Kubernetes infrastructure and CI/CD pipelines; troubleshoot production incidents; lead end-to-end infrastructure projects; establish deployment standards and operational procedures; mentor engineers; monitor observability, security, and access controls to reduce risk and improve developer productivity.
Top Skills: AWSBashCi/CdCloudFormationDockerEksGoKubernetesNew RelicOpentelemetryOtelPrometheusPythonTerraform
8 Days AgoSaved
Remote
Remote San Diego, CA
80K-100K Annually
Senior level
80K-100K Annually
Senior level
Blockchain • Software • Financial Services • Cryptocurrency
Design, build, and scale distributed backend services supporting hundreds of thousands of users. Develop efficient Golang and Python code, optimize infrastructure, make architectural decisions, conduct code reviews, and collaborate with frontend and mobile engineers. The role also involves technical planning, platform innovation, and contributing to product evolution in an autonomous startup environment.
Top Skills: AWSBlockchainCassandraClickhouseDappsDockerGoGrafanaKubernetesMongoDBPostgresPrometheusPythonSentrySmart ContractsTimescaledb
8 Days AgoSaved
Remote
Remote San Diego, CA
Mid level
Mid level
Blockchain • Software • Financial Services • Cryptocurrency
Lead engineering as CTO or founding engineer for an early-stage crypto company. Own browser extension and backend development, smart contract integrations, cross-chain capabilities, DeFi and wallet primitives, and transaction frameworks. Collaborate on product planning and iterative feature development while providing technical leadership, autonomy, and ownership in a remote team.
Top Skills: Account AbstractionAWSBrowser ExtensionsEthers.JsGoIntent-Based Transaction FrameworksJavaScriptMevPythonReactRustSmart ContractsSolidityTypescriptWagmiWeb3.Js
8 Days AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Blockchain • Software • Financial Services • Cryptocurrency
Design blockchain architecture and modular node components, develop blockchain and DeFi protocols, operate servers and blockchain nodes at scale, and modify node software. The role requires proficiency in two specified programming languages, experience with cloud infrastructure and blockchain systems, meaningful open-source contributions, strong self-direction, and availability to work Pacific Time hours.
Top Skills: AWSAzureEthereumGethGoJavaScriptOp StackOvhPythonRustTypescriptZk-Rollups
8 Days AgoSaved
Remote
Remote San Diego, CA
150K-180K Annually
Mid level
150K-180K Annually
Mid level
Blockchain • Software • Financial Services • Cryptocurrency
Leads a distributed, cross-functional engineering team; establishes development, testing, and deployment practices; partners with leadership and product on roadmaps and prioritization; coaches, evaluates, and develops engineers; supports hiring, performance management, culture building, and delivery of reliable, high-quality systems.
Top Skills: CryptocurrencyDistributed SystemsGoNftsPythonWeb3
Reposted 17 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
90K-124K Annually
Mid level
90K-124K Annually
Mid level
Aerospace • Robotics • Software • Defense
Develop and maintain C/C++ swarm autonomy code for ground stations and drones, implement swarming algorithms and communications protocols, extend Python web services, collaborate on architecture, and support field testing and demonstrations.
Top Skills: Ai Coding Assistance ToolsAndroidCC++CSSEmbedded LinuxFlutterHTMLJavaJavaScriptKotlinLinuxMvcMvpMvvmPosixPub/SubPythonReact NativeRtosSitlStandard Template LibraryStm32XamarinYocto
Reposted 17 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
120K-200K Annually
Senior level
120K-200K Annually
Senior level
Aerospace • Robotics • Software • Defense
Maintain and extend C++ swarm code for ground stations and drones, develop swarming algorithms and communication protocols, improve software architecture and engineering processes, and support Python-based ground station web services.
Top Skills: Ai Coding Assistance ToolsAndroidCC++CSSEmbedded LinuxFlutterHTMLJavaJavaScriptKotlinLinuxPosixPub/SubPythonReact NativeRtosSitlStlStm32XamarinYocto
Reposted 8 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
Expert/Leader
Expert/Leader
Manufacturing
The CAD/Flow Methodology Development leader will define and scale EDA infrastructure, automate design flows, debug issues, and establish metrics for silicon delivery efficiency in cross-functional environments.
Top Skills: CmakeEda CadGitKubernetesLsfMakePythonShellSlurmTcl
Reposted 8 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
120K-304K Annually
Senior level
120K-304K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead end-to-end design and delivery of AI-infused, enterprise full-stack applications on Azure. Architect resilient solutions, build Copilot/agentic features, enforce engineering best practices, mentor engineers, collaborate with PM/UX teams, ensure quality/reliability, and support production services and integrations.
Top Skills: .NetAksAsp.NetAzureAzure Container AppsAzure Event HubAzure Function AppsAzure Service BusAzure SqlAzure SynapseAzure Web AppsCC#C++Claude CliCopilot Cli/SdkCosmos DbDataverseDynamics 365Github CopilotJavaJavaScriptMicroservicesNoSQLPower AppsPower AutomatePower PlatformPowerfxPythonReactRest ApisSQLTypescript
Reposted 8 Days AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Information Technology • Consulting
The Senior Software Engineer will develop reliable systems for IoT fleet management, create user interfaces, and support data engineering tasks.
Top Skills: Asp.Net CoreAWSAzureC#HTTPMvcPythonRest ApiSQLTcp/IpUdp
Reposted 8 Days AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Artificial Intelligence • Blockchain • Software • Web3
As an AI Applications Engineer, you will bridge AI research and implementation, driving experiments, building infrastructure, and releasing products to improve user experience and metrics.
Top Skills: A/B TestingAIApi IntegrationsMachine LearningPython
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Reposted 8 Days AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Security • Software
The Senior Platform Engineer designs and operates Kubernetes infrastructure, automates tasks, enforces platform standards, and collaborates across teams to improve engineering velocity and scalability.
Top Skills: ArgocdAWSElkFalconFluxGitGrafanaGrypeHelmIstioKubernetesKyvernoOpaOpensearchOpentofuPrometheusPythonSyftTerraform
Reposted 8 Days AgoSaved
Remote
Remote San Diego, CA
88K-147K Annually
Junior
88K-147K Annually
Junior
Fashion
Build and improve Stitch Fix's cloud-native platform and developer tooling. Develop IaC, CI/CD, containerized workflows, and automation to improve deployment reliability and developer experience. Collaborate with engineers, debug systems, and explore LLM-powered tooling under mentorship.
Top Skills: AWSCircleCIDockerEcsEksGoPulumiPythonRubyTerraform
Reposted 8 Days AgoSaved
Remote
Remote San Diego, CA
70K-121K Annually
Mid level
70K-121K Annually
Mid level
Insurance
Design, build, and support cloud-native full stack or backend Java products using TDD, CI/CD, microservices and event-driven patterns. Collaborate with product teams, provide production support, implement monitoring and ensure secure, performant systems.
Top Skills: AngularjsAvscDatadogDockerGithub ActionsJava 17JenkinsJSONKafkaKubernetesMongoDBOpenapiPythonReactRedux ToolkitRest ApisSpring Boot 3.XTypescript
Reposted 8 Days AgoSaved
Remote
Remote San Diego, CA
180K-222K Annually
Senior level
180K-222K Annually
Senior level
Information Technology
The Engineering Manager will lead teams building a scalable device passport platform, mentor engineers, manage backlog, and contribute coding while ensuring quality and documentation standards.
Top Skills: AWSPostgresPythonSQL
Reposted 8 Days AgoSaved
Remote
Remote San Diego, CA
150K-175K Annually
Senior level
150K-175K Annually
Senior level
Information Technology
As a Senior Software Engineer, you will architect and implement Python-based systems, lead feature design and delivery, ensure scalability and reliability, and mentor junior engineers.
Top Skills: Aws CloudPostgresPythonRestful Apis
Reposted 8 Days AgoSaved
Remote
Remote San Diego, CA
120K-135K Annually
Senior level
120K-135K Annually
Senior level
Information Technology
As a mid-level Software Engineer, you'll deliver Python-based platform features, collaborate with teams, and maintain system reliability and scalability.
Top Skills: Aws CloudPostgresPythonUbuntu/Linux
Reposted 8 Days AgoSaved
Remote
Remote San Diego, CA
Mid level
Mid level
Fintech • Software • Financial Services
Responsible for maintaining and enhancing data warehouses and pipelines, developing scalable ETL processes, data analysis, and reporting through visualization tools like PowerBI.
Top Skills: AWSAzureBigQueryDatabricksGitGoogle Cloud PlatformPower BIPysparkPythonSnowflakeSQL
Reposted 8 Days AgoSaved
Remote
Remote San Diego, CA
190K-270K Annually
Senior level
190K-270K Annually
Senior level
Artificial Intelligence
Design and build scalable backend components and indexing pipelines for semantic and hybrid retrieval, build retrieval orchestration and knowledge-graph services, improve retrieval quality via evaluation and observability, design APIs, and optimize latency, throughput, cost, reliability, and security for large-scale AI inference and retrieval workloads.
Top Skills: C++ElasticEmbeddingsGoHybrid RetrievalJavaKnowledge GraphKubernetesLlmsObservability FrameworksOpensearchPineconePulumiPythonRagRustSemantic SearchTerraformVector Databases
Reposted 8 Days AgoSaved
In-Office or Remote
Remote San Diego, CA
40K-76K Annually
Mid level
40K-76K Annually
Mid level
Healthtech
Develop and enhance GIS capabilities within a core C++ OMS application, configure map services, design cartography, integrate spatial databases, resolve spatial data issues, and collaborate with product teams using Jira and GitHub.
Top Skills: C#C++GitJavaJIRAOracle SpatialPostgisPythonSQL
Reposted 8 Days AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Edtech
The Senior DevOps Engineer manages cloud infrastructure using IaC, enhances CI/CD pipelines, mentors teams, and drives automation initiatives for improved developer experience.
Top Skills: AWSC#ChefDockerGithub ActionsGoPHPPythonTerraform
Reposted 8 Days AgoSaved
Remote
Remote San Diego, CA
Senior level
Senior level
Edtech
Seeking a Senior DevOps Engineer for OpenSesame, focusing on CI/CD pipelines, cloud infrastructure, and automation. Responsibilities include improving developer experience and mentoring teams.
Top Skills: AWSC#ChefDockerGithub ActionsGoPHPPythonTerraform
Reposted 8 Days AgoSaved
Remote
Remote San Diego, CA
120K-165K Annually
Senior level
120K-165K Annually
Senior level
Fitness • Healthtech • Software
Own reliability and security of CI/CD and production services: define SLI/SLOs, lead incident response and postmortems, build observability (Datadog), operate Kubernetes and IaC (Terraform), harden pipelines with SAST/DAST/SCA and policy-as-code, and coach teams on reliability and operational best practices.
Top Skills: AWSCi/CdConftestDastDatadogDockerGithub ActionsGoInfrastructure As CodeKubernetesKyvernoOpa/RegoPythonSastScaTerraformTypescript
9 Days AgoSaved
Remote
Remote San Diego, CA
163K-264K Annually
Senior level
163K-264K Annually
Senior level
Information Technology • Software
Design, build, and operate scalable backend services and APIs for LaunchDarkly’s experimentation platform. Own systems supporting experiment setup, event ingestion, metric computation, and results processing. Contribute to architecture, reliability, observability, deployment safety, incident response, and technical direction. Collaborate with product, design, data science, and engineering teams, investigate production issues, participate in on-call, and mentor teammates through reviews and knowledge sharing.
Top Skills: Amazon RedshiftC++ClickhouseDatabricksGoGoogle BigqueryInfrastructure As CodePostgresPythonRustSnowflake
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