Top Remote Python Jobs in San Diego, CA

Design, implement, and maintain Plume's core blockchain node and validator software; develop scalable, secure protocol features across the full crypto/DeFi stack; tackle distributed-systems and networking challenges; integrate backend services and on-chain UX; and iterate on protocol design to improve performance and reliability.

Define technical vision and implement scalable microservices and core platform features. Lead API and data-model design, develop backend solutions with automated tests, drive CI/CD and migration from monolith to microservices, collaborate cross-functionally, and mentor engineers.

Build front-end or back-end features across the full SDLC, collaborate with product and engineering teams, design scalable solutions, contribute to CI/CD and data modeling best practices, and deliver high-quality, production-ready code with automated tests.

Lead design, implement, and maintain cloud-native microservices and platform services for high-throughput supply chain systems. Own architecture, reliability, CI/CD, monitoring, and incident response. Mentor engineers, establish engineering standards, and collaborate with product, data science, and customer teams to deliver scalable API and data solutions.

Design, implement, and maintain Python backend services and scalable data pipelines using dataframes, Parquet, and Databricks. Optimize distributed processing, build APIs, ensure data quality and observability, and mentor engineers.

As a Solutions Architect at phData, you'll lead the design and implementation of cloud-native data platforms, driving optimization and automation for clients using AWS, Azure, and Snowflake.

Lead and manage the core engineering team for Family History Trees, delivering high-throughput, scalable, near-zero-downtime systems. Collaborate with product, design, QA, DBAs, and operations; architect, implement, deploy, and document services; mentor and recruit talent; establish quality metrics and remove project blockers.

As a Principal Software Dev Engineer, lead full-stack engineering, oversee complex initiatives, mentor engineers, and align technical strategies with business goals to enhance content management systems.

Lead and mentor a software engineering team to deliver scalable production systems. Provide technical leadership, manage people processes (1:1s, reviews, hiring), collaborate with Product and Design, drive sprint planning, and champion engineering best practices including testing, observability, and incident management.

Build and maintain production-grade Python APIs and data processing systems, design EHR integrations (HL7/FHIR), lead AWS-based feature development, troubleshoot production issues, enforce testing standards, refactor and optimize systems, mentor junior engineers, and collaborate cross-functionally.

Lead architecture and delivery for document generation systems, mentor engineers, build greenfield internal tooling, enforce shift-left quality practices, and ensure HIPAA-compliant, secure integrations with data science and clinical platforms.

Build and operate the Internal Engineering Platform: automate CSP resource provisioning, manage Kubernetes clusters, networking, scheduling/autoscaling, maintain Crossplane and Terraform modules, partner with application teams, and participate in on-call rotations to ensure reliability and scalability.

Lead and grow an SRE team for FedRAMP/DoD-compliant government cloud environments. Ensure availability, performance, capacity, incident response, automation, and Continuous Monitoring (ConMon) to maintain ATOs and regulatory evidence for audits.

Design, build, and operate high-performance distributed authentication and real-time inference services. Implement scalable cloud APIs, distributed training and deployment pipelines, CI/CD, observability, and reliability practices. Lead incident response, on-call rotations, staged rollouts, and post-incident improvements while managing model lifecycle, data quality, and production monitoring.

Serve as the technical contact for strategic partners to integrate Transmit Security's CIAM, authentication, and fraud APIs. Provide code samples, reference architectures, integration reviews, troubleshooting, and partner-facing assets. Support enablement via workshops, solution design, and pre-sales engineering while feeding partner feedback into product roadmap.

The Senior QA Automation Engineer will develop and execute test automation strategies, collaborate with teams, analyze software, and ensure quality in mortgage technology systems.

The Senior Software Engineer will modernize the USPS shipping technology by refactoring legacy services and designing cloud-native solutions in Go, while ensuring high-performance and reliability for users.

The GCP Cloud Infrastructure Architect will design and develop cloud-native infrastructure for Ford utilizing GCP and ensure optimal performance, security, and compliance while collaborating with teams and maintaining documentation.

The Deployment Engineer will manage the full deployment lifecycle for retail locations, coordinate installations, troubleshoot issues, and develop automation tools to enhance deployment efficiency.

The Robot Operations Analyst monitors the Tally robot fleet, troubleshoots issues, automates detection and remediation tasks, and collaborates with cross-functional teams to ensure operational reliability and service quality.

The Forward Deployed Engineer collaborates with customer teams to design, prototype, and troubleshoot real-time communication and voice AI applications on the LiveKit platform.

The role involves developing scalable solutions using cloud-native technologies, focusing on cloud networking, writing efficient code, and enhancing network infrastructure at Netflix.

Lead engineering organization for Weave’s platform services, set technical strategy, ensure secure and scalable systems, mentor engineering managers, and drive cross-functional initiatives.

As a Senior Software Engineer, you will develop and optimize high-performance APIs, ensuring reliable, low-latency access to user data and collaborating closely with various teams on essential API infrastructure.

The AWS DevOps Data Engineer will build AWS infrastructure, create implementations, manage GitLab and transition to GitHub Actions, develop ETL scripts, and improve CI/CD pipelines in a collaborative environment.