Top System Engineer Jobs

Operate and maintain high-throughput sequencing platforms; design and execute microfluidic device and sequencing experiments; analyze sequencing and process data to produce actionable insights; troubleshoot device, instrument, and software issues; apply DOE, process control, and data analytics; maintain experimental records and prepare technical reports while collaborating across biochemistry, electrochemistry, and materials science teams.

Operate and maintain a high-throughput single-molecule sequencing platform; design and run experiments on microfluidic devices; analyze sequencing and process data to generate actionable insights; apply DOE and process control methods; troubleshoot device, instrument, and software issues; maintain records and prepare technical reports.

Senior Systems Test Automation Engineer responsible for designing test plans and strategies, building and maintaining test automation and build/release systems, executing hardware and software validation tests, triaging and resolving issues with engineering teams, and delivering test reports to engineering, operations, and management.

Support NGS and sample-prep platforms by troubleshooting hardware, software, and assays; perform failure analysis, testing, validation, and reliability improvements; analyze data with JMP or R; maintain technical documentation and collaborate with cross-functional teams in a lab environment.

Lead and execute verification & validation for electro-mechanical medical devices, drive requirements engineering, risk management and FMEA, perform root cause analysis and DOE, lead cross-functional teams for design reviews and troubleshooting, and manage engineering projects to deliver product improvements.

Hands-on systems engineer to support product development and on-market support for electro-mechanical diagnostic devices. Develop and execute V&V test strategies, analyze data, troubleshoot and perform root cause analysis, support requirements and risk management (FMEA), and drive product/process improvements.

Design custom robotic systems for pharmaceutical/biotech customers; collaborate with electrical and robotics engineers, manufacturing, vendors, and customers; produce detailed drawings, organize BOMs, and manage engineering change orders through the product lifecycle.

Design Release Engineer responsible for end-to-end development, validation, and launch of heated and ventilated seat systems. Owns technical definitions, specifications, packaging, supplier coordination, validation testing, issue resolution, and change management. Collaborates with cross-functional teams (Electrical, HVAC, HMI, Body) to ensure thermal performance, safety, manufacturability, and system integration across vehicle programs.

Implement, maintain, and support enterprise messaging platforms including Microsoft Exchange 2010/2013 and Lync 2010/2013. Manage high-availability Exchange features (DAG, CAS arrays, load balancers, UM, BES), enterprise archiving (Symantec Enterprise Vault), and email protection/management tools (Proofpoint, Mimecast). Collaborate with stakeholders and apply messaging best practices; relevant certifications are a plus.

Senior Solutions/System Engineer for pre-sales and consulting: perform technical scoping, proposal development, requirements gathering and infrastructure design. Must have deep knowledge of Active Directory, Microsoft servers, virtualization, and networking. Expertise in Exchange, SCCM, Office 365/Azure, or Lync Server 2013 is required; multiple technology proficiencies preferred.

Design and implement customer infrastructure solutions, assist in pre-sales technical scoping and proposal development, and provide technical support to colleagues. Prefer experience with requirements gathering and infrastructure design and deep familiarity with Microsoft and Citrix technologies.

Provide systems architecture, integration, deployment, and operations support for server- and web-based applications. Design and operate multi-tier Windows Server environments, implement security and monitoring, perform troubleshooting, deployments, stress testing, documentation, and collaborate with architects and project managers to deliver infrastructure solutions.

Lead system architect responsible for designing and delivering complex SQL Server 2008 R2/SSIS solutions. Author and review design documents, model systems, perform coding and code reviews, tune environments, write queries and ad-hoc reports, and collaborate with management, business SMEs, and development teams across project lifecycles.

Provide SME-level support for VMware and Linux rollouts, ensure build compliance, design and implement high-availability infrastructure, troubleshoot complex multi-platform issues, produce documentation, coach junior admins, and coordinate with teams to deliver and support production hosting environments.

Deploy and manage applications across staging and production using ITIL change control. Implement and tune monitoring, troubleshoot hardware/application incidents, participate in on-call rotation, support escalations, collaborate with development to resolve issues, and improve operations via automation and scripting. Work with SQL Server, IIS, Windows Servers, SAN/HBA, replication and clustering.

Build and maintain scalable deployment, orchestration, data pipelines, and observability tooling for agentic AI frameworks. Integrate and evaluate AI agents and model-serving systems, automate evaluation pipelines, produce dashboards and reports, and collaborate with global engineering teams to ensure reliable, tested deployments and evaluations.

Lead maintenance, troubleshooting, programming, and optimization of the plant DCS, PLCs, turbine controls, HMIs, historians, CEMS, and industrial networks. Provide technical leadership for system upgrades, cybersecurity, commissioning, outages, root cause analyses, and operator support. Develop control logic, interfaces, and documentation while collaborating with Operations, Maintenance, Engineering, OEMs, and contractors to improve reliability, performance, compliance, and asset availability.

The role involves researching AI system architecture, developing performance models, analyzing AI workloads, and guiding design decisions while collaborating across teams.

The role involves researching AI system architecture, developing performance models, making design decisions, and leading architecture strategies. It requires collaboration across teams to evaluate AI workloads and scalability issues.

Responsible for the design, integration, and management of complex nuclear systems using systems engineering processes and frameworks, ensuring project requirements are met.

The System Support Engineer investigates and resolves in-service hardware/software issues, conducts testing in the lab, performs root cause analysis, and coordinates issue resolution with teams.

The Staff Systems Test Engineer will ensure the quality and reliability of integrated solutions through systematic testing, collaboration with teams, and development of automated tests.

The System Engineer will support the modernization of SharePoint architecture and provide engineering support for various systems while ensuring compliance with industry standards.

The role involves designing and implementing conversational AI systems, managing prompt orchestration, and ensuring conversational quality through advanced evaluation frameworks.

The System Integration Engineer will develop cybersecurity platforms, manage integrations, oversee simulations, and ensure operational readiness in healthcare IT environments.