Top Senior Machine Learning Jobs in Charleston, SC

7 Days AgoSaved
In-Office or Remote
Charleston, SC
130K-170K Annually
Senior level
130K-170K Annually
Senior level
Aerospace • Security • Energy • Industrial
Lead product strategy, requirements, and roadmap development for Honeywell Forge cloud applications serving utilities. Own AI and analytics capabilities for grid operations, DER management, rate design, and utility programs. Conduct customer and market discovery, competitive analysis, and voice-of-customer research. Partner with solution architects, sales, customers, and engineering to prioritize and deliver B2B SaaS products that generate measurable utility operational value.
Top Skills: AICisCloud ArchitectureCloud-Native SoftwareData LakesData PlatformsDermsGisMachine LearningMdmSaaSUtility Analytics
7 Days AgoSaved
Remote
Charleston, SC
130K-170K Annually
Senior level
130K-170K Annually
Senior level
Aerospace
Lead product strategy, requirements, roadmap, and AI capabilities for Honeywell Forge cloud applications serving utilities. Conduct customer and competitive discovery, translate utility workflows into product investments, define commercial opportunities, and partner with engineering to prioritize and deliver cloud-native B2B software. The role focuses on AI for grid operations, DER management, rate design, and utility program performance while ensuring measurable operational value.
Top Skills: AICisCloud ArchitectureCloud-Native SoftwareData LakesDermsGisHead-End SystemsHoneywell ForgeMachine LearningMdmMdmsSaaSUtility Analytics
7 Days AgoSaved
Remote or Hybrid
Charleston, SC
147K-240K Annually
Senior level
147K-240K Annually
Senior level
eCommerce • Fashion • Retail
Own the global consumer engagement and personalization domain across digital channels. Assess current capabilities, define multi-year strategy and roadmap, recommend personalization infrastructure investments, and translate priorities into shipped products. Partner with engineering, data science, design, marketing, legal, and regional teams to deliver scalable experiences. Establish metrics, run cross-market experiments, optimize performance, and make global versus localized decisions. Influence executives, mentor product managers, and apply AI, identity resolution, and generative AI to personalization.
Top Skills: Communications PlatformsCustomer Data PlatformsDashboardsData Clean RoomsDecisioning EnginesGenerative AiMachine LearningOrchestration ToolingRecommendation EnginesSQL
7 Days AgoSaved
Remote
Charleston, SC
85K-108K Annually
Senior level
85K-108K Annually
Senior level
Fintech • Payments • Financial Services
Manage the AI opportunity roadmap for Risk Services, prioritizing use cases, coordinating internal data science teams and external vendors, translating business needs into requirements, and supporting AI governance, compliance, explainability, auditability, implementation, adoption, and benefits realization. The role focuses on business outcomes and solution delivery rather than hands-on model development.
Top Skills: Artificial IntelligenceData GovernanceData ScienceGenerative AiMachine Learning
7 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Information Technology • Professional Services
Designs, develops, deploys, maintains, and optimizes ETL processes and cloud-based system integrations for healthcare data warehousing and business intelligence. Works with DHA and Cerner inpatient and outpatient data, develops database procedures, validates migrations, performs data mapping and modeling, and supports data science and machine learning teams. The role also documents processes, tunes performance, captures client requirements, and manages data transformation initiatives.
Top Skills: Amazon RedshiftAnacondaAWSAzureCernerInformaticaMachine LearningMicrosoft Office SuiteMySQLOpenshiftPl/SqlPostgresPowerpivotPythonRSQLSQL ServerSsasSsisSsrsT-SqlTalendZeppelin
7 Days AgoSaved
Remote
Charleston, SC
182K-342K Annually
Senior level
182K-342K Annually
Senior level
Artificial Intelligence • Software
Own and develop SandboxAQ’s intellectual property function, including patent portfolio strategy, invention harvesting, prosecution, lifecycle management, outside counsel oversight, freedom-to-operate analyses, trademark clearance, and trade secret programs. Partner with scientists, engineers, and business teams to protect innovations, inform product strategy, support transactions, and build scalable IP processes in a fast-growing AI-focused company.
Top Skills: Artificial IntelligenceMachine Learning
Reposted 12 Days AgoSaved
Remote
Charleston, SC
210K-260K Annually
Senior level
210K-260K Annually
Senior level
Fintech • Information Technology • Software
Manage a team of data scientists to develop fraud detection models, lead planning and collaboration with leadership, and communicate outcomes effectively while maintaining strong business intuition and technical leadership.
Top Skills: Aws Ec2Aws RdsAws RedshiftAws S3PostgresPython 3
7 Days AgoSaved
In-Office or Remote
Charleston, SC
105K-192K Annually
Senior level
105K-192K Annually
Senior level
Information Technology • Legal Tech • Professional Services • Analytics • Business Intelligence
Develop and deploy NLP and machine learning models for classification, sentiment analysis, entity extraction, information retrieval, and user intent detection across large-scale legal, financial, news, and business datasets. Design scalable data science pipelines, evaluate modern AI algorithms and tools, translate business needs into technical solutions, and collaborate with product and engineering teams. Mentor junior scientists and contribute to model deployment, monitoring, maintenance, and development best practices.
Top Skills: Aws Ec2Aws LambdaCaffeCaffe2Deep LearningElasticsearchGensimInformation RetrievalJanusgraphJavaKerasLarge Language ModelsLdaMachine LearningMlopsMxnetNeptuneNlpNumpyOpennlpPandasPythonPyTorchScalaScikit-LearnSolrSpacySparkSQLStanford NlpTensorFlow
7 Days AgoSaved
Remote
Charleston, SC
80K-100K Annually
Senior level
80K-100K Annually
Senior level
Agency • Digital Media • Analytics • Consulting
Manage paid media strategies and campaigns across search, social, display, and programmatic channels. Advise clients using integrated paid, organic, and analytics data; oversee campaign performance, keyword research, ad copy, landing page recommendations, and presentations. Build client relationships, mentor account associates, collaborate with SEO and data teams, and use AI to improve workflows and outcomes.
Top Skills: Artificial IntelligenceData VisualizationDisplay AdvertisingExcelGoogle SuiteMachine LearningPaid SearchPaid SocialProgrammatic AdvertisingSeo
7 Days AgoSaved
Remote
Charleston, SC
80K-100K Annually
Senior level
80K-100K Annually
Senior level
Agency • Digital Media • Analytics • Consulting
Develop and lead paid media strategies across search, social, display, and programmatic channels. Manage campaign strategy, performance analysis, testing, optimization, and integrated paid and organic recommendations. Consult with clients, present results, build relationships, mentor account associates, and identify data-driven growth opportunities. Use AI tools to improve workflows and contribute insights across the team.
Top Skills: Artificial IntelligenceData Visualization ToolsDisplay AdvertisingExcelGoogle WorkspaceMachine LearningPaid SearchPaid SocialProgrammatic Advertising
8 Days AgoSaved
Remote
Charleston, SC
124K-198K Annually
Senior level
124K-198K Annually
Senior level
Software
Leads AI-enabled Finance transformation initiatives from roadmap development through implementation and adoption. The role analyzes Finance processes, identifies automation opportunities, documents requirements, coordinates cross-functional Technology and Finance teams, manages change and training, tracks ROI and KPIs, and supports governance, compliance, SOX controls, and system integration across enterprise applications.
Top Skills: Ai AgentsAnaplanBotsCoupaFloqastIntelligent Workflow AutomationMachine LearningNetSuiteRobotic Process AutomationServicenowWorkato Agentic AiWorkday
8 Days AgoSaved
In-Office or Remote
Charleston, SC
219K-301K Annually
Senior level
219K-301K Annually
Senior level
Big Data • Machine Learning • Software • Analytics • Big Data Analytics
Leads technical strategy and product adoption for major Retail and CPG enterprise accounts as Databricks’ primary technical voice. Partners with account executives, guides customers through data and AI transformations, builds technical champions, aligns solutions to business strategies, and mentors team members. Requires extensive pre-sales, big data, cloud, data science, programming, and production data systems experience.
Top Skills: Artificial IntelligenceCloud ComputingDatabricksHadoopJavaMachine LearningMppNoSQLOlapOltpPythonRScala
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8 Days AgoSaved
Remote
Charleston, SC
94K-165K Annually
Senior level
94K-165K Annually
Senior level
Healthtech • Insurance
Owns CareSource’s EDI platform vision, roadmap, backlog, and delivery. Translates healthcare, regulatory, and integration requirements into technical specifications; partners with engineering, architecture, QA, DevOps, trading partners, and business teams; coordinates releases and Agile delivery; monitors transaction performance, defects, SLAs, and platform telemetry; drives data quality, observability, automation, compliance, documentation, and continuous improvement across EDI capabilities.
Top Skills: AgileAIAPIsCloudEdiEdifecsFacetsFhirMachine LearningX12
8 Days AgoSaved
Remote
Charleston, SC
150K-188K Annually
Senior level
150K-188K Annually
Senior level
Artificial Intelligence • Information Technology • Consulting
Build and lead Nebius’s federal affairs function in Washington, D.C. Develop policy strategy across AI regulation, trade, energy, infrastructure, and national security; establish bipartisan relationships with Congress and executive agencies; represent the company in federal initiatives and coalitions; assess regulatory risks; coordinate with legal, communications, and infrastructure teams; manage outside lobbying partners; and hire staff as the function scales.
Top Skills: Artificial IntelligenceCloud InfrastructureMachine Learning
8 Days AgoSaved
Remote
Charleston, SC
161K-350K Annually
Senior level
161K-350K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
Lead research, architecture, and production deployment of large-scale algorithms for budget pacing, bid optimization, and marketplace balancing in Yahoo’s DSP. Apply control theory, optimization, and machine learning to real-time systems, while establishing AI-augmented research and engineering workflows. Own multi-quarter initiatives, define evaluation frameworks, guide technical strategy, collaborate with product and engineering leadership, mentor scientists and engineers, and communicate complex research and architectural decisions to executives.
Top Skills: Agentic Orchestration FrameworksAISparkC++ChatgptClaude CodeCodexControl TheoryConvex OptimizationCursorDistributed Data ArchitecturesGeminiGithub CopilotJavaMachine LearningPythonReal-Time BiddingRtb AuctionsSQLStochastic Optimization
8 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Information Technology • Professional Services • Security • Cybersecurity
Lead the definition and evolution of cybersecurity technology platform and service offerings for cyber defenders and CISOs. Drive requirements through software and service lifecycles, deliver differentiated offerings to market, and guide cross-functional teams toward consistent, high-quality execution. The role requires deep expertise in at least two cybersecurity domains, managed services experience, strong communication skills, executive presentation ability, and awareness of AI’s impact on cyber defense.
Top Skills: Application SecurityArtificial IntelligenceCloud SecurityCnappContinuous Controls MonitoringCspmCybersecurityEndpoint Detection And ResponseMachine LearningManaged Detection And ResponseNetwork Detection And ResponseSecurity Data LakesSIEMThreat Exposure ManagementVulnerability Management
8 Days AgoSaved
In-Office or Remote
Charleston, SC
142K-185K Annually
Senior level
142K-185K Annually
Senior level
Digital Media • Fintech • Information Technology • Machine Learning • Financial Services • Cybersecurity • Automation
Lead the vision, strategy, roadmap, backlog, delivery, adoption, and lifecycle management of an enterprise AI platform. Manage three direct reports and collaborate across technology, cybersecurity, risk, legal, compliance, data, and analytics. Ensure secure, scalable, governed, and responsible AI capabilities while translating business and technical priorities into measurable product outcomes. Drive stakeholder alignment, platform adoption, continuous improvement, executive communication, and team development in a highly regulated environment.
Top Skills: APIsArtificial IntelligenceCloud PlatformsGenerative AiIdentity And Access ManagementKanbanLarge Language ModelsLlmopsMachine LearningMlopsObservabilityScrum
8 Days AgoSaved
Remote
Charleston, SC
80K-100K Annually
Senior level
80K-100K Annually
Senior level
Agency • Digital Media • Analytics • Consulting
Manage paid social campaigns and full-funnel strategies across Meta, LinkedIn, TikTok, Pinterest, Snapchat, and other paid channels. Oversee client accounts, analyze performance, identify growth opportunities, build client relationships, and collaborate with SEO, creative, and analytics teams. Contribute to thought leadership, coach associates, maintain quality standards, and explore automation, AI, and LLM search visibility initiatives.
Top Skills: Artificial IntelligenceData Visualization ToolsExcelGoogle SuiteLinkedInMachine LearningMetaPinterestSnapchatSQLTiktok
13 Days AgoSaved
Remote
Charleston, SC
200K-250K Annually
Senior level
200K-250K Annually
Senior level
Fintech • Information Technology • Software
Leads and manages an applied machine learning team developing fraud detection and identity verification models. Responsibilities include people management, coaching, code review, production ML systems, model lifecycle ownership, experimentation, deployment, monitoring, fraud research, cross-functional prioritization, and communicating results. The role remains hands-on while partnering with Product, Engineering, Risk, and leadership to drive measurable business impact and shape future product strategy using machine learning and AI.
Top Skills: AWSElasticsearchFlyteLlmsMlflowNeo4JOpensearchPandasPostgresPython 3Scikit-LearnXgboost
8 Days AgoSaved
In-Office or Remote
Charleston, SC
1-4 Hourly
Senior level
1-4 Hourly
Senior level
HR Tech • Software
Lead the strategy, design, deployment, and scale-up of AI-powered health products across the Global South. Own product roadmaps, execution, government-system integration, stakeholder adoption, partnerships, grant development, and portfolio expansion. Collaborate with engineering, machine learning, program, and domain teams to deliver sustainable, measurable public-health impact.
Top Skills: AIData SystemsDigital PlatformsMachine Learning
Reposted 9 Days AgoSaved
Remote
Charleston, SC
130K-155K Annually
Senior level
130K-155K Annually
Senior level
Artificial Intelligence • Mobile • Software
Lead post-sales success for enterprise SaaS customers, drive adoption, monitor account health and model performance, manage escalations, run QBRs, partner cross-functionally to ensure renewals and expansions, and deliver measurable business outcomes while advising on identity verification and fraud detection solutions.
Top Skills: AIAPIsBehavioral Risk SignalsBi ToolsBiometric MatchingChurnzeroComputer VisionDocument AuthenticationGainsightIdentity Verification PlatformsLiveness DetectionMachine LearningTableauTotango
9 Days AgoSaved
Remote
Charleston, SC
60K-90K Hourly
Senior level
60K-90K Hourly
Senior level
Information Technology • Database • Consulting
Performs advanced physical and remote insurance premium audits for business clients. Reviews business records, interviews owners and managers, investigates exposures, documents findings, prepares written audit reports, schedules assignments, communicates results, and submits completed work for quality review. The auditor must manage deadlines independently, correct returned audits, maintain accurate records, and use Microsoft Office applications. This remote role requires reliable transportation, a valid driver’s license, strong analytical and communication skills, and at least five years of premium insurance auditing experience.
Top Skills: ExcelMachine LearningMicrosoft Office SuiteOutlookWord
9 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Information Technology • Transportation • Travel
Leads the company’s adoption of AI, analytics, automation, and business intelligence. Builds AI-powered workflows, Excel solutions, natural-language data interfaces, dashboards, forecasts, predictive analytics, and automated reporting using Snowflake, SQL, Tableau, and related tools. Partners across business functions to identify opportunities, improve data quality, automate repetitive processes, and deliver scalable decision-support solutions. Establishes responsible AI practices and advances an AI-first analytics culture.
Top Skills: APIsChatgptClaudeData PipelinesDbtETLExcelGeminiGenerative AiLlmsMachine LearningMicrosoft CopilotOffice ScriptsOpenai ApiPower PivotPower QueryPredictive AnalyticsSnowflakeSQLTableauVBA
9 Days AgoSaved
Remote
Charleston, SC
140K-190K Annually
Senior level
140K-190K Annually
Senior level
Artificial Intelligence • Big Data • Cloud • Information Technology • Machine Learning
Lead data engineering and machine learning initiatives by designing, architecting, developing, and supporting GCP data pipelines. Create information architecture documentation, estimate and plan technical work, collaborate with project teams and business analysts, and translate requirements into technical designs. Develop Python-based ELT pipelines, optimize BigQuery SQL, support CI/CD, and provide technical leadership to projects and teams.
Top Skills: Apache AirflowSparkBigQueryBusiness Intelligence (Bi)Ci/CdCloud ComposerDataprocDbtEltGoogle Cloud Platform (Gcp)Google Cloud Storage (Gcs)Machine LearningPythonSQLUnix/Linux Shell Scripting
9 Days AgoSaved
Remote
Charleston, SC
120K-240K Annually
Senior level
120K-240K Annually
Senior level
Cloud • Enterprise Web • Internet of Things • Mobile • Software
Own strategic enterprise accounts across expansion and new-logo sales motions. Build executive relationships, develop account plans, run account-based outbound, navigate complex buying committees, deliver consultative demonstrations, negotiate contracts, and close high-value SaaS deals. Partner with Customer Success, Business Development, and Marketing while maintaining Salesforce pipeline and forecasts. Success requires consistently meeting quota through longer-cycle, multi-stakeholder deals and contributing to the evolving enterprise sales playbook.
Top Skills: Artificial IntelligenceCmmsGongMachine LearningOutreachPredictive AnalyticsSaaSSalesforceZoominfo
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