Top Senior Machine Learning Jobs in Charleston, SC

Reposted 4 Days AgoSaved
In-Office or Remote
Charleston, SC
Senior level
Senior level
Fintech • Financial Services
Lead credit analytics for the Send Now Pay Later product: build and optimize valuation, vintage and NPV models; manage credit policies, portfolio monitoring, and NPL reporting; integrate and test scoring models with engineering/data science; and research alternative data to improve predictive performance.
Top Skills: AIBlockchainDbtMachine LearningPythonRSQLStablecoinsWhatsapp
Reposted 4 Days AgoSaved
In-Office or Remote
Charleston, SC
Senior level
Senior level
Fintech • Financial Services
Lead fraud detection and mitigation for a conversational BNPL product: define fraud typologies, analyze repayment/chargeback trends, own fraud KPIs, design policies, collaborate on ML models and decisioning workflows, and coordinate SARs with Compliance.
Top Skills: AIBi Visualization ToolsBlockchainMachine LearningProvenirPythonRSQLStablecoinsTaktileWhatsapp
Reposted 4 Days AgoSaved
In-Office or Remote
Charleston, SC
Senior level
Senior level
Fintech • Financial Services
Lead fraud risk for a conversational lending product (SNPL): define first-party fraud typologies, analyze repayment and chargeback trends, own fraud KPIs, design automated/manual blocking policies, coordinate ML/rules with central Fraud and Data teams, and liaise with Compliance on SARs and loan abuse.
Top Skills: AIBi Visualization ToolsBlockchainMachine LearningProvenirPythonRSQLStablecoinsTaktileWhatsapp
Reposted 4 Days AgoSaved
In-Office or Remote
Charleston, SC
Senior level
Senior level
Fintech • Financial Services
Lead quantitative credit analytics for a Send Now Pay Later (SNPL) product: build and maintain credit policies, pricing and NPV models, vintage analysis, portfolio monitoring, model integration/testing, and alternative data evaluation to optimize approval rates and manage portfolio health.
Top Skills: DbtMachine LearningPythonRSQL
Reposted 4 Days AgoSaved
Remote
Charleston, SC
165K-185K Annually
Senior level
165K-185K Annually
Senior level
Cloud • Software
The Engineering Manager will oversee a team managing cloud data engineering projects, client engagement, and technical leadership, ensuring successful delivery and mentorship.
Top Skills: Amazon Web Services (Aws)EmrHadoopMachine LearningSpark
Reposted 4 Days AgoSaved
Remote
Charleston, SC
159K-215K Annually
Senior level
159K-215K Annually
Senior level
Information Technology • Security • Software • Cybersecurity
The Engineering Manager for Smart Signals leads a team, manages execution, and maintains technical depth in backend systems for fraud detection. They shape strategy and coordinate across teams to enhance product quality.
Top Skills: Backend SystemsFraud DetectionMachine LearningSecurity Signals
Reposted 4 Days AgoSaved
Remote
Charleston, SC
150K-240K Annually
Senior level
150K-240K Annually
Senior level
Artificial Intelligence • Information Technology • Machine Learning
The Senior Backend Data Engineer will extend data ingestion and processing pipelines, build APIs and backend services, and provide technical leadership.
Top Skills: Api GatewayAWSCognitoDynamoDBGoLambdaMachine LearningPythonRust
Reposted 4 Days AgoSaved
Remote or Hybrid
Charleston, SC
250K-300K Annually
Senior level
250K-300K Annually
Senior level
Cloud • Digital Media • Enterprise Web • Marketing Tech • Software
Design, optimize, and scale ClickUp's search infrastructure using OpenSearch/ElasticSearch. Improve relevance, speed, and real-time indexing; build vector/semantic search capabilities; create measurement frameworks; integrate search with AI and product features; troubleshoot at scale; and mentor junior engineers to maintain high search quality under heavy load.
Top Skills: Distributed Data ProcessingElasticsearchMachine LearningNlpOpensearchSemantic SearchTypescriptVector EmbeddingsVector Search
Reposted 4 Days AgoSaved
Remote or Hybrid
Charleston, SC
200K-250K Annually
Senior level
200K-250K Annually
Senior level
Cloud • Digital Media • Enterprise Web • Marketing Tech • Software
Design, scale, and optimize ClickUp's search infrastructure using OpenSearch/Elasticsearch. Improve relevance, speed, and real-time indexing, build vector search capabilities, create evaluation frameworks, and collaborate with AI/backend/product teams to integrate and troubleshoot search at scale.
Top Skills: ElasticsearchMachine LearningNlpOpensearchTypescriptVector EmbeddingsVector Search
Reposted 4 Days AgoSaved
Remote
Charleston, SC
155K-185K Annually
Senior level
155K-185K Annually
Senior level
AdTech
The Senior AI Data Engineer will design and build scalable data pipelines, ensure data quality, and support AI product development through a unified analytical data framework.
Top Skills: AIAirflowSparkAzure SynapseBigQueryClickhouseDatabricksDbtDelta LakeMachine LearningPrefectPythonSnowflakeSQL
Reposted 4 Days AgoSaved
Remote
Charleston, SC
183K-224K Annually
Senior level
183K-224K Annually
Senior level
Fintech
The Principal Data Scientist will design, develop, and deploy machine learning models, innovating methodologies and collaborating across teams to enhance financial decision-making and risk management.
Top Skills: AirflowBentomlChalkDvcKubernetesMachine LearningMlflowNumpyPandasPydata StackScikit-LearnSpark
Reposted 4 Days AgoSaved
Remote
Charleston, SC
183K-224K Annually
Senior level
183K-224K Annually
Senior level
Fintech
As a Principal Data Scientist, you'll design and deploy cutting-edge machine learning models to drive financial success for customers and guide technical teams.
Top Skills: AirflowKubernetesMachine LearningMlflowNumpyPandasScikit-LearnSpark
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Reposted 4 Days AgoSaved
In-Office or Remote
Charleston, SC
140K-180K Annually
Senior level
140K-180K Annually
Senior level
Artificial Intelligence • Legal Tech • Natural Language Processing • Generative AI
Lead technical pre-sales and enterprise rollouts by owning infrastructure strategy, PoCs, migrations (on‑prem to cloud), DMS/CRM integrations, InfoSec discussions, and stakeholder engagement with C-level sponsors to enable scalable deployments and upsell opportunities.
Top Skills: Cloud InfrastructureCRMDevsecopsDocument Management SystemsGenerative AiImanageLarge Language ModelsMachine LearningMicrosoft Word
Reposted 4 Days AgoSaved
Remote
Charleston, SC
137K-152K Annually
Senior level
137K-152K Annually
Senior level
Healthtech • HR Tech • Sales • Social Impact • Software
As a Senior Data Scientist, you will identify business opportunities, build machine learning solutions, partner cross-functionally, and translate analyses into actionable insights.
Top Skills: Business Intelligence ToolsMachine LearningPythonRSQL
Reposted 4 Days AgoSaved
Remote
Charleston, SC
Senior level
Senior level
Defense
The Solutions Architect will bridge customers and sales, ensuring the technical fit of software solutions, leading demos, and managing deployments effectively.
Top Skills: AIEdge ComputingMachine Learning
Reposted 4 Days AgoSaved
Remote or Hybrid
Charleston, SC
104K-154K Annually
Senior level
104K-154K Annually
Senior level
Consumer Web • eCommerce • Fashion • Retail
The Senior Manager will oversee the fraud lifecycle, optimize detection strategies, conduct fraud reviews, collaborate with teams, and manage risk reporting.
Top Skills: AIMachine LearningSnowflakeSQL
Reposted 4 Days AgoSaved
Remote
Charleston, SC
200K-225K Annually
Senior level
200K-225K Annually
Senior level
Artificial Intelligence • eCommerce • Software
Design and build backend systems and APIs for AI-driven products, ensuring scalability, reliability, and integration of ML models while collaborating with engineering and product teams.
Top Skills: APIsAWSAzureDockerGCPKubernetesLlmsMachine LearningNoSQLPythonSQL
4 Days AgoSaved
Remote
Charleston, SC
150K-195K Annually
Senior level
150K-195K Annually
Senior level
Software • Cryptocurrency • Web3
Lead product analytics to improve user growth, engagement, retention, and revenue. Design and analyze A/B and multivariate experiments, perform funnel/cohort analyses, maintain KPIs and dashboards, ensure event tracking, leverage ML and AI tools for advanced analyses, and translate insights into product recommendations across cross-functional teams.
Top Skills: A/B TestingAi-Assisted ToolsMachine LearningMultivariate TestingPropensity ScoringPythonRSegmentationSQLTableau
4 Days AgoSaved
Remote or Hybrid
Charleston, SC
Senior level
Senior level
Fintech • Financial Services
Lead design and scaling of a unified fraud and risk platform. Own roadmap, fraud metrics, SQL-based analysis, A/B testing, real-time detection models, and cross-functional delivery to balance customer experience and risk mitigation.
Top Skills: A/B TestingAPIsArtificial IntelligenceBlockchainData PipelinesMachine LearningRiskifiedSardineSQL
4 Days AgoSaved
Remote
Charleston, SC
85K-110K Annually
Senior level
85K-110K Annually
Senior level
AdTech • Agency • Marketing Tech • Social Media
Lead analyses measuring campaign impact, build tagging models (prompt engineering and ML), synthesize insights across programs, analyze experiments including RCTs, and produce presentations and post-campaign reports for internal teams and clients.
Top Skills: BigQueryGCPMachine LearningNatural Language ProcessingPrompt EngineeringPythonRSQL
4 Days AgoSaved
Remote
Charleston, SC
180K-200K Annually
Senior level
180K-200K Annually
Senior level
Cloud • Software • Transportation
Lead North America revenue growth by building relationships, managing pipeline, responding to RFPs/RFIs, coordinating cross-functional teams, tracking activity in Salesforce, representing Optibus at industry events, and delivering data-driven sales forecasts.
Top Skills: AIMachine LearningOptimization AlgorithmsSalesforce
Reposted 4 Days AgoSaved
Remote
Charleston, SC
175K-190K Annually
Senior level
175K-190K Annually
Senior level
Healthtech • Biotech
The role oversees analytical characterization and comparability studies for biologics, ensuring regulatory compliance and leadership in product development.
Top Skills: Artificial IntelligenceBiophysical AssaysChromatographic MethodsFunctional AssaysMachine LearningMass Spectrometry
Reposted 4 Days AgoSaved
Remote
Charleston, SC
100K-150K Annually
Senior level
100K-150K Annually
Senior level
Digital Media
The Customer Solutions Manager will engage customers, lead solution adoption, coordinate with internal teams, and ensure customer success in telecom solutions.
Top Skills: Machine LearningPythonSQLTableauTelecom Rf
Reposted 4 Days AgoSaved
Remote
Charleston, SC
5-10 Annually
Senior level
5-10 Annually
Senior level
Artificial Intelligence • Information Technology • Cybersecurity
The role involves developing and improving TTS/Voice Generation models, training, fine-tuning, evaluating speech models, and collaborating across research, engineering, and product teams in a fast-paced startup environment.
Top Skills: Computer VisionGenerative AiMachine LearningNatural Language UnderstandingSpeech AiTtsVoice Generation
Reposted 4 Days AgoSaved
Remote
Charleston, SC
195K-235K Annually
Senior level
195K-235K Annually
Senior level
Hospitality
As a Staff Data Scientist, you will lead product strategy by building predictive models, optimizing matching algorithms, and guiding product innovations in a consumer tech environment.
Top Skills: Data WarehousingMachine LearningPythonRSQL
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