Top IT Jobs in Charleston, SC

The Senior IT Security Engineer strengthens cybersecurity across architecture reviews, AI and emerging technology assessments, IAM governance, vulnerability management, third-party risk, security assurance, incident response, phishing simulations, automation, and regulatory compliance. The role validates security controls, supports remediation, develops risk metrics and reporting, oversees identity platforms, and partners with technology, business, audit, compliance, procurement, and vendors in a regulated banking environment.

Leads secure, reliable IT infrastructure supporting distributed clinical research sites and remote employees. Manages enterprise networking, Azure and Microsoft 365 services, endpoint platforms, automation, AI-enabled operations, vendors, budgets, and technology projects. Oversees site deployments, security and compliance initiatives, service delivery, and operational improvements while recruiting, coaching, and developing technical teams.

Evaluates IT infrastructure, applications, cybersecurity, compliance, costs, scalability, and compatibility during mergers and acquisitions. Leads technology integration and separation planning, identifies modernization and consolidation opportunities, conducts IT capability and maturity assessments, recommends governance frameworks, and aligns technology strategy with business objectives. The role also prepares diligence reports and executive presentations while collaborating with internal and external stakeholders in fast-paced transaction environments.

Provides application and system support, troubleshoots issues, manages testing and deployments, develops ETL tools and reports, and conducts business analysis. The role defines requirements, identifies IT solutions, supports system integrations, documents procedures, guides team members, and communicates with stakeholders. It also applies agile practices and supports process improvements within a financial services environment.

Leads IT governance, risk, and compliance activities, including SOC 2 readiness, audit planning and execution, policy development, control assessments, evidence gathering, remediation tracking, and regulatory research. Partners with auditors, control owners, IT leadership, and GRC team members to maintain compliance with NIST CSF and financial services regulations. Provides guidance on audit and policy matters while improving GRC processes and tooling.

Monitors and triages security alerts, investigates and documents incidents, supports identity and access management, vulnerability remediation, security awareness, phishing simulations, incident response, and security control checks. Collaborates with IT teams and an MSSP to resolve security issues, tune security tools, maintain documentation, and escalate threats. Requires availability for identity and access management, incident response, and escalation outside standard business hours.

Designs and manages AWS cloud infrastructure and Amazon EKS platforms using GitLab CI/CD and Infrastructure as Code. Builds ETL workflows and scalable data pipelines for analytics and AI workloads, supports MLOps/AIOps and FinOps capabilities, troubleshoots Linux systems, and improves platform performance, security, scalability, and availability.

Designs and maintains secure AWS cloud infrastructure, Amazon EKS clusters, and GitLab CI/CD pipelines. Integrates vulnerability scanning, compliance controls, secrets management, and container security into DevSecOps workflows. Supports MLOps/AIOps platforms, AI model deployment, data pipelines, monitoring, and automation. Ensures FedRAMP, NIST, audit, and internal security compliance while collaborating across engineering teams.

Lead and grow Proof’s IT Engineering team while transforming corporate IT from reactive help desk support into an engineering-first function. Own the strategy and roadmap for identity, access, endpoints, SaaS, vendors, procurement, and budgeting. Mentor engineers, implement infrastructure-as-code, CI/CD, GitOps, automation, and AI-driven operations, reduce ticket volume through root-cause fixes, and partner with InfoSec on security and compliance.

Lead life sciences IT compliance and quality consulting projects, including CSV, CSA, risk-based validation, regulatory assessments, audits, data integrity reviews, and compliance modernization. Develop validation plans, requirements, risk assessments, test plans, trace matrices, policies, and client presentations. Evaluate regulated systems and infrastructure, support technology implementations, communicate with technical and executive stakeholders, and contribute to proposals, business development, and client relationship growth.

Provides enterprise technical leadership for cloud and network modernization across DoD environments. Engineers multi-cloud integrations, secure connectivity, cloud access points, routing and switching, data center technologies, F5 ADC solutions, and Zero Trust architectures. Leads migration planning, compliance with DoD security frameworks, Tier 3/4 troubleshooting, technical documentation, executive recommendations, and cross-disciplinary initiatives. The hybrid role supports DLA and requires periodic onsite work for NIPR/SIPR operations.

Owns enterprise ITSM and related platforms in a secure environment. Configures, maintains, troubleshoots, and extends COTS applications; builds API, webhook, middleware, directory, and scripting-based integrations; develops workflows, automations, utilities, and lightweight applications; and resolves authentication, plugin, and configuration issues. The role translates operational needs into maintainable technical solutions, documents implementations, improves reliability, and works independently with stakeholders and adjacent technical teams.

Lead and execute remote technical implementations for dental practices from signing through go-live. Configure PMS integrations, set up remote access and network configurations, manage AWS-hosted Windows VMs/ETL, handle support volume, liaise with MSPs, and improve onboarding processes and automation while partnering with cross-functional teams.

Manages corporate AMEX cards, reconciles event and travel expenses, supports financial and administrative operations, and ensures accurate, compliant, timely processing of expenditures. Collaborates with finance, events, and task order teams to validate travel requirements and maintain documentation. Requires strong organization, prioritization, spreadsheet, and financial reporting skills, plus proficiency with Microsoft Office, Excel, expense management systems, and card platforms.

Design, administer, optimize, and govern an enterprise Databricks Lakehouse Platform. Responsibilities include managing workspaces, Unity Catalog, compute, workflows, data pipelines, security controls, observability, performance, cost optimization, CI/CD, infrastructure automation, disaster recovery, and platform upgrades. The role also supports audits, compliance, troubleshooting, documentation, technical standards, and mentorship while integrating Databricks with enterprise data, business intelligence, and AI/ML environments.

Leads enterprise strategy, architecture, delivery, governance, and operations across data, analytics, information management, automation, AI, and GenAI. Drives transformation toward governed data foundations, reusable data products, data marketplaces, self-service analytics, and responsible AI. Oversees platforms, pipelines, dashboards, automation initiatives, budgets, vendors, and senior technical teams while partnering with business, Legal, Compliance, Quality, and Security. Builds training, adoption, stewardship, and change-management programs across a global life sciences organization.

Supports information technology audit and advisory engagements by documenting systems, risks, and controls; testing IT general, automated, and SOX controls; reviewing evidence; preparing workpapers and reports; identifying control gaps; communicating with clients; and managing assignments across multiple engagements. The role focuses on developing expertise in IT audit, banking regulatory guidance, internal controls, and emerging technology risks.

Build and enhance scalable full-stack applications and microservices using React and Java or Python. Diagnose performance and architectural issues, develop production-grade user interfaces, collaborate in Agile environments, and deliver cloud-based solutions. The role includes end-to-end implementation ownership, technical decision-making, team leadership, mentoring, and applying AI-assisted development tools. Work is remote eligible and supports mission-critical customer systems.

Owns the lifecycle, security, and administration of company devices, Mac MDM, user accounts, endpoint controls, networks, servers, backups, logging, and vulnerability remediation. Supports field deployments and customer-site infrastructure, maintains IT policies and documentation, coordinates shared services with parent-company IT, evaluates new tools, and communicates project risks and tradeoffs to leadership.

Leads enterprise IT and cybersecurity strategy, teams, budgets, service delivery, infrastructure reliability, security governance, incident response, compliance, audits, vendor relationships, and operational resilience. Advises executives and boards on technology risk, investments, material incidents, and risk acceptance while establishing standards, metrics, roadmaps, and continuous improvement practices.

Provides advanced helpdesk support, serves as an escalation point, troubleshoots Windows and Mac hardware and software, manages endpoint and mobile devices, supports identity and SaaS access, documents solutions, assists with onboarding and offboarding, and improves IT processes. The role also supports office technology and workplace-related IT needs while mentoring junior technicians and communicating technical concepts clearly to employees.

Manage enterprise metadata, business glossaries, data catalogs, and end-to-end data lineage for a federal case management modernization program. Configure governance and metadata platforms, integrate data sources and pipelines, establish standards and workflows, monitor metadata quality, support compliant data sharing, develop governance metrics, document procedures, and train data stewards and business users.

Design, build, and run cloud-based automated test frameworks and scripts for React/Node applications. Configure CI/CD pipelines, test environments, and data sets; validate APIs and containerized apps; collaborate with manual testers and development teams using Agile/DevSecOps practices.

Leads data operations and governance for a large cloud modernization program. Oversees data platforms, pipelines, integrations, analytics environments, incidents, service requests, releases, performance, resilience, and data quality. Coordinates cloud, engineering, application, cybersecurity, and infrastructure teams; maintains operational documentation, dashboards, metrics, and risk logs. Partners with governance and engineering teams to implement metadata, lineage, stewardship, automation, CI/CD, observability, and SRE practices. Leads personnel, manages escalations, briefs executives, and drives continuous operational improvement.

Governs enterprise change enablement and release management processes to support stable, compliant technology delivery. Responsibilities include risk-based change approvals, CAB facilitation, release planning, deployment coordination, audit readiness, rollback and testing oversight, CI/CD integration, production support readiness, KPI reporting, stakeholder communications, and continuous process improvement. The role also manages ITSM and release tooling, supports major incidents and emergency changes, and collaborates with engineering, QA, operations, security, business stakeholders, and auditors.