Top Remote Software Engineer Jobs in St. Louis, MO

Build and scale full-stack healthcare applications using TypeScript, React, and/or .NET on Azure. Design event-driven integrations, translate complex requirements into technical solutions, support production systems, and contribute to planning and design reviews. Lead through mentoring, code reviews, pairing, and technical problem-solving while delivering software predictably. Preferred experience includes healthcare applications, EHR and FHIR integrations, RPA, CI/CD, automated testing, and open-source contributions.

Build and operate product and technical initiatives across Boulevard’s event-driven platform, including scheduling, booking, marketing automation, and business tools. Partner with Product and Design, contribute to architecture, develop frontend or backend systems, maintain software quality through testing and observability, support production systems, mentor engineers, and improve delivery practices using AI-assisted development tools.

Lead design and implementation of high-throughput, low-latency programmatic bidding systems. Collaborate with ML engineers to deploy real-time inference, optimize distributed microservices, run experiments and quantitative analysis, and partner with product to ship scalable features. Foster operational excellence, mentor engineers, and continuously improve performance and reliability.

Architects and develops secure, high-performance distributed applications, APIs, microservices, and data pipelines on AWS. Leads application architecture, cloud infrastructure, data governance, testing automation, CI/CD, security, performance optimization, and technical modernization. Coordinates complex project lifecycles, manages risks and schedules, advises management, resolves cross-functional technology issues, documents systems, and mentors junior engineers in a financial services environment.

Design and build scalable distributed backend systems in Golang using PostgreSQL and Redis. Architect highly available services across microservices, networking, and cloud platforms; prototype and productionize platform capabilities and internal tooling; collaborate with CTO leadership on strategic initiatives; and influence engineering standards. The role focuses on greenfield AI infrastructure, developer tooling, performance, reliability, and systems operating at scale.

Build and maintain full-stack software products across frontend, backend, data, and AI layers. Own product architecture, deployment, observability, reliability, and maintenance; establish unified data models, secure access controls, AI guardrails, and engineering standards. Collaborate directly with non-engineering users to create self-service workflows and translate ambiguous needs into practical solutions. Ship production LLM-powered systems and support governed data transformation, quality, lineage, and testing.

Lead the design, development, testing, deployment, and optimization of scalable distributed applications and web services. Build Python/FastAPI backend services, ReactJS interfaces, and PostgreSQL data systems. Deploy and monitor cloud-native applications on GCP, collaborate on AI/ML integrations, contribute to architecture and SDLC practices, and mentor junior developers through code reviews and technical leadership.

Own complex trading-platform escalations from reproduction through permanent resolution. Build production fixes, internal admin tools, automation, and observability improvements using C#/.NET and React. Investigate distributed systems, database state, race conditions, and integrations; participate in on-call and production incident response; lead post-incident reviews; and collaborate with engineering, QA, Cloud Ops, Product, and support stakeholders.

Lead the technical vision and development of Elasticsearch’s core search infrastructure, including indexing, retrieval, query execution, and relevance. Research advances in search systems and algorithms, guide long-term technical roadmaps, collaborate across teams, mentor expert engineers, and contribute hands-on to high-performance distributed software. Serve as a subject-matter authority while driving projects from concept through completion.

Build, test, deploy, and maintain accounting software for transaction categorization, revenue recognition, and accurate financial reporting. Own projects end to end, create technical designs and rollout plans, conduct code reviews, collaborate cross-functionally, investigate production issues, improve reliability, and mentor teammates. The role involves working with typed Python, JavaScript, TypeScript, Vue.js, Terraform, AWS, and PostgreSQL in a remote environment.

Lead ambiguous, multi-team software projects for core accounting systems. Set technical direction, make architectural decisions, build and deploy reliable software, review technical specifications, investigate production issues, and improve system reliability. Collaborate with product and cross-functional stakeholders, mentor and sponsor engineers, and maintain high standards for clean, tested code. The role focuses on typed Python backend services, financial systems, integrations, and cloud infrastructure.

Design and implement scalable, secure cloud-native microservices and data platforms. Collaborate with product and stakeholders, mentor junior engineers, build CI/CD pipelines, and translate business needs into developer-ready stories.

As a Unity Engineer, you'll implement features, ensure performance optimization, debug issues, and collaborate with the team to enhance gameplay for mobile titles.

Lead platform reliability: define SLOs/error budgets, own observability and deploy pipelines, harden integrations with dental systems, operate LLM-driven workflows safely, build incident practices, and raise engineering reliability across the company.

Design and implement automated tests, frameworks, and fixtures for embedded hardware and software. Execute regression, performance, stress, and reliability tests. Build and maintain R&D and production test environments, collaborate to debug firmware and hardware, define testability in design reviews, support manufacturing partners, and enable customers onsite (10-20% travel).

As a Full Stack Developer at Nurture, you'll design scalable APIs, develop user interfaces, and ensure data flow across systems in a collaborative environment.

Lead technical delivery of Enterprise Content Management (ECM) solutions, guiding design, development, integrations, CI/CD, automated testing, and cloud modernization. Provide hands-on .NET development, incident resolution, operational readiness, and coach engineering teams while ensuring security, retention, and governance for content services.

Lead design and implementation of Pinterest Edge systems (CDN, TLS, DNS, proxies) to manage automation traffic and rate limiting at scale. Develop request-processing logic in Envoy, collaborate with vendors and platform teams, mentor engineers, use AI to accelerate workflows, and participate in on-call incident response and reliability improvements.

Lead implementation of software safety programs for underwater robotic/autonomous vehicles per MIL-STD-882. Produce safety plans and assessments, perform hazard analyses, track coverage metrics, catalog safety artifacts, review software independently, and present findings at reviews and customer meetings. Coordinate across programs and support demanding schedules with occasional travel.

The role involves building decision science libraries and tools for mineral exploration, collaborating with teams to improve decision-making processes.

The Embedded Software Engineer will analyze and develop embedded software systems, provide customer support, and apply software engineering and cybersecurity methods.

Improve performance and scalability of web applications by identifying and resolving front-end and back-end bottlenecks. Optimize load times, API responses, and database queries; develop scalable features across the stack, monitor performance, conduct code reviews, troubleshoot production issues, and collaborate with product, design, and engineering teams.

Design, build, and maintain large-scale, resilient systems; develop features and automated tests; mentor engineers; implement CI/CD and cloud-native infrastructure; integrate AI tools; lead projects, code reviews, and cross-team initiatives while improving engineering practices and documentation.

Lead design and delivery of platform capabilities that power a Federated GraphQL API and event-driven systems. Build and optimize gRPC endpoints, GraphQL APIs, and SQL for scale; own observability (DataDog, Bugsnag), mentor engineers, drive integrations, improve performance and reliability, and support customer-facing product teams across the organization.

Own the technical direction of a core Helius backend system, including architecture, reliability, performance, roadmap, and production operations. Design scalable distributed systems, storage, streaming, or edge infrastructure; drive profiling and performance improvements; establish operational excellence; partner with founders on strategy; mentor engineers; and lead ambiguous cross-team initiatives.