Top Remote Software Engineer Jobs in St. Louis, MO

Senior Java engineer delivering AI-augmented production features and modernizations across a Java/Python/AWS stack. Pair with engineers to embed agentic practices, own systems end-to-end, participate in AI-augmented reviews, and judge agent use versus human intervention.

Senior Java engineer delivering AI-augmented production features and modernizations across a Java/Python/AWS stack. Own systems end-to-end, pair with engineers to transfer agentic practices, perform AI-augmented code reviews, and judge when to trust or intervene with agent outputs.

Build and scale backend systems for a high-traffic donor CRM and payments platform. Own performant SQL and realtime querying, optimize payment flows, implement AI agents, and collaborate across product and design to ship resilient, production-grade features at scale.

Develop distributed, production-grade microservice systems and scalable data-processing infrastructure on Linux. Lead service mesh, contract-first API, gRPC, and Protocol Buffers initiatives; design fault-tolerant architectures and observability systems; operate containerized distributed platforms; and mentor junior and mid-level engineers. The role also emphasizes AI-assisted development, technical communication, and documentation, with preferred experience in industrial automation, monorepos, real-time processing, edge computing, and infrastructure as code.

Lead architecture and hands-on implementation of a full-stack platform and production AI systems (LLM integration, RAG, agentic workflows). Ship user-facing features across frontend, backend, data pipelines, infrastructure, testing, and monitoring. Set technical direction, tooling, and engineering practices while partnering with product and program teams.

Design, build, and operate scalable, highly concurrent backend services in Go. Architect distributed, fault-tolerant systems, optimize performance and reliability, define APIs and service boundaries, improve observability and operational readiness, and collaborate cross-functionally to support mission-critical autonomous deployments.

Design, build, and maintain automated migration workflows to onboard dental practices. Implement C#, .NET, and PowerShell scripts, manage ETL processes and SQL data transformations, troubleshoot live routines, leverage AI tools to speed development, and produce technical documentation to ensure secure, reliable migrations.

Lead design and implementation of core platform infrastructure for an Agentic AI platform. Build high-performance Rust systems, support production deployments, collaborate with ML engineers, design scalable data architectures, troubleshoot performance and scalability issues, and cultivate a collaborative, inclusive engineering culture.

Own and advance Chainguard’s internal Developer Platform, including monorepo CI/CD, shared build infrastructure, and Agentic AI tooling. Improve developer experience, build reliability, change throughput, observability, and secure software delivery. Design scalable platform architecture, consolidate build systems, establish standardized delivery blueprints, automate developer toil, partner with engineering teams, and mentor engineers while contributing to technical direction and DORA-aligned outcomes.

Lead the migration of Vanta’s resource data platform from MongoDB to schema-aware PostgreSQL while maintaining API compatibility and data integrity. Design high-throughput Kafka and S3 ingestion pipelines, eventual-consistency strategies, query infrastructure, tenant isolation, and reliable distributed systems. Set architectural direction across storage, caching, and streaming technologies; mentor engineers; drive cross-team technical roadmaps; and improve reliability, observability, and operational excellence.

Design and build cloud cost-management capabilities, including forecasting, anomaly alerts, cost allocation, data pipelines, transformation models, visualizations, and reusable UI components. Own features end to end from planning through release while improving application reliability and performance. Collaborate closely with engineers and founding team members, contribute to technical design and roadmap decisions, and work pragmatically in a fast-moving distributed startup environment.

Design, build, and operate shared cloud infrastructure across AWS, Kubernetes, Terraform, Databricks, and Cloudflare. Lead SRE and DevOps initiatives involving reliability, observability, CI/CD, incident response, disaster recovery, cost optimization, and developer self-service. Partner with application and data engineering teams to improve workload operations, deployment safety, and infrastructure scalability. Participate in on-call rotations and contribute to technical standards, architecture, documentation, and sustainable 24/7 operations.

Design, build, and maintain secure, performant browser extensions for Chrome, Edge, and other browsers using Manifest V3 and modern APIs. Develop features integrating with web content, backend services, and endpoint agents; optimize reliability; monitor evolving browser standards; and participate in testing, code reviews, and process improvement. The role requires investigating third-party web applications, understanding extension security models, and coordinating effectively with backend and non-browser engineering teams.

Define architecture and technical direction for Catalyst’s distributed data platform, including messaging, state management, reconciliation, streaming, storage, CI/CD, and Kubernetes operations. Build Go and Python frameworks, improve reliability and SLOs, lead incident response, maintain secure dependency and artifact delivery, and develop infrastructure automation. Collaborate across teams and with customers, review designs and code, establish engineering standards, and travel internationally up to 25% to support mission-critical deployments.

Owns the architecture and implementation of high-performance real-time streaming systems, including media ingestion, buffering, relay, packetization, telemetry synchronization, and distribution. Designs protocol modules, resolves interoperability challenges, improves latency and throughput, and maintains production reliability through testing, observability, incident response, and automated deployments. Partners with stakeholders, documents architectural trade-offs, mentors engineers, leads technical rituals, and travels internationally up to 25% to support customer and mission requirements.

Design, implement, and support high-performance storage and query infrastructure handling billions of events. Independently scope and deliver complex projects, optimize query performance, improve reliability, participate in on-call rotations, define KPIs and SLOs, reduce operational toil, debug production issues, collaborate cross-functionally, and mentor engineers.

Technical leader designing and implementing backend features for a FHIR-based healthcare data platform. Owns high-level design, microservices, data pipelines, CI/CD, cloud deployments, and clinical reasoning components (dQM/CQL). Guides customer implementations, resolves complex technical challenges, and mentors junior developers to uphold coding and architecture standards.

Design, develop, and maintain scalable web and backend applications, public REST APIs, automated testing frameworks, and cloud-native services. Improve scalability, stability, monitoring, auto-scaling, CI/CD, security, and reliability. Conduct code reviews, troubleshoot production issues, document root causes and operational procedures, and collaborate with distributed engineering teams to deliver fleet-management platforms.

Design, build, and optimize scalable cloud and web software with focus on infrastructure, performance, and hardware integration for IoT devices. Collaborate with hardware teams to ensure connectivity and high availability, implement new features, and improve system efficiency.

Develop open source SDKs, enterprise APIs, UIs, and backend systems supporting large-scale computer vision datasets. Build scalable, maintainable, performant, and well-tested software for unstructured data and AI workflows. Contribute to enterprise deployments across customer clouds and on-premises environments, while improving tooling, automation, engineering practices, and open source community initiatives in a remote-first team.

Develop custom ServiceNow applications for work order management, scheduling, and dispatch. Collaborate with stakeholders and technical SMEs, enhance event rules and CMDB binding, build REST integrations and user interfaces, and configure Discovery, Service Mapping, MID Servers, Service Graph Connectors, and multisource CMDB. The role also involves creating discovery patterns, preventing duplicate CIs, configuring identification rules, migrating patterns across environments, and supporting multi-tier service discovery.

The Staff SDET will design and implement automated test frameworks using TypeScript, collaborate with developers, and enhance testing processes within CI/CD pipelines.

Provide technical and architectural leadership to the software development team, design software solutions, mentor team members, and drive projects to completion.

The Senior Software Engineer will modernize USPS shipping technology, refactor legacy systems for cloud integration, and develop high-performance services using Go, while collaborating with teams and addressing production challenges.

Design, build, and operate high-performance Places/Search API services; drive architecture and scalability decisions; improve code quality and operational standards; mentor engineers; run experiments and telemetry-driven analysis; participate in feature delivery, on-call rotation, and customer-facing collaboration with automotive and mapping partners.