Top Remote IT Jobs in St. Louis, MO

Operate and scale endpoint and identity systems for a distributed Mac fleet; automate IAM and cross-functional workflows (Okta Workflows, RPA); implement PAM and Device Trust; ensure Zero Trust, DLP, and compliance (SOC2, HIPAA, HITRUST); serve as tier-2 on-call escalation and drive cost and operational efficiencies.

Lead end-to-end deployments of Medicaid MMIS/MES and related Health IT systems. Plan, schedule, and manage go-lives, deployment readiness, integrations, and installation of network equipment. Maintain implementation plans, coordinate cross-functional teams and stakeholders, ensure CMS/state compliance, and provide status reporting. Remote role with 25–50% travel.

Build and operate an AWS-native data lake and AI gateway. Implement and maintain lakehouse architecture (Iceberg) using Glue, Athena, and S3; manage infrastructure as code (Terraform); run reliable data pipelines; operate LLM gateway/Bedrock; enforce security, IAM, networking, and secrets controls; partner with IT and Security.

Serve as embedded IT risk partner for engineering and technology teams, owning IT SOX readiness, control design, testing coordination, remediation oversight and auditor liaison. Assess ITGCs and application controls across cloud, DevOps, CI/CD, IAM and Kubernetes environments. Drive control automation, continuous monitoring, evidence quality, and translate technical risks into practical guidance for engineers, Finance, and external auditors.

Provide Level II help desk support for managed services clients: resolve phone and ticketed issues, escalate and assist Level I, maintain KB and documentation, configure endpoints, troubleshoot networks, security, printers and mobile devices, and communicate SLA status.

Hunt and close net-new enterprise and mid-market US-headquartered clients with European operations for multi-country IT hardware procurement. Build pipeline via outbound prospecting, qualify opportunities, create proposals, manage CRM and forecasts, collaborate with regional teams and vendors, represent Presidio at events, and meet revenue and margin targets.

Sell IT staffing solutions into life sciences clients by developing new business, managing client relationships, creating account strategies, collaborating with recruiting teams, and providing market intelligence on talent and compensation. Focus areas include data engineering, cybersecurity, cloud, automation, and R&D IT to support regulated environments and accelerate project delivery.

Lead and govern global IT change management lifecycle: intake, risk-based assessment, approvals, execution, validation, post-change review, reporting, and continuous improvement. Coordinate across IT teams, vendors, MSPs, and regions to minimize service disruption, maintain audit-ready records, deliver training, and drive tooling and process automation opportunities to support high-availability and data center operations.

Lead and sustain large-scale HPC systems supporting NOAA/NWS forecasting. Manage scheduler/software stack (PBS Pro/Slurm), optimize performance and throughput, troubleshoot multi-node Linux clusters, develop scripts, and support 24/7 operations with occasional travel and on-call duties.

Perform risk-based IT security and compliance audits (policy, general controls, firewall) against FFIEC/GLBA and other guidelines; coordinate assessments, report findings, assist sales, and perform onsite testing with up to 25% travel.

The DoD SkillBridge Internship offers active-duty military members IT and cybersecurity training, certifications, and networking opportunities to prepare for civilian careers in IT.

Lead integration of technology into information systems, design data warehouse and BI capabilities, define data architecture and dictionaries, centralize disparate data, design dashboards, document system architecture, perform data quality and management, and provide solution engineering, pilots, and enablement for analytics and resource management.

Source and qualify leads on Upwork, respond to inbound inquiries, write tailored proposals, provide initial consultations and rough estimates, negotiate and upsell, and maintain clear communication between clients and technical teams.

Responsible for IT support and administration for Commercial systems. Partners with business owners to ensure system performance, compliance, and operational excellence across various business functions.

Lead the design and execution of Grafana's IT SOX program: scope, risk assessment, control design, testing, documentation, deficiency remediation, and external auditor coordination. Assess ITGCs and application controls across cloud/SaaS and ERP systems, leverage AI/automation, manage co-source partners, and report risks and remediation to senior leadership.

Drive B2B IT sales by prospecting, qualifying leads, delivering demos and presentations, responding to RFPs, building pipelines and partnerships, and closing deals for IT services (ServiceNow, application development, cloud, cybersecurity) across onshore/offshore/hybrid delivery models.

Provide remote technical support for hardware, software, and network issues; install, configure, and maintain computer systems and LAN/WAN; troubleshoot system and network problems; assist with VPN setup; use Remedy, Jira, and other IT management tools; collaborate with IT team.

The IT Recruiter will manage the recruitment lifecycle, source IT talent, conduct interviews, and ensure smooth integration of new hires.

Lead IT operations for a multi-site ambulatory surgery network, managing infrastructure, clinical and business systems, security and compliance, service desk, vendor relationships, and IT budgeting. Ensure uptime, drive integrations and migrations, execute DR/BC plans, and report operational metrics while partnering with the CIO on strategy and roadmaps.

Lead and evolve secure, automated cloud platforms and CI/CD pipelines using IaC, containers, and Kubernetes. Integrate security tooling, mentor engineers, optimize cloud cost and reliability, and produce technical documentation while supporting Generative AI development workflows.

Lead a 5–8 person Data Science team to develop and operationalize FWA detection models using SAS and Python on multi‑payer healthcare claims. Oversee model development, data pipelines, quality reviews, stakeholder presentations, and collaboration with SMEs and BI developers. Split role ~40% management, 60% hands-on coding/analysis.

Administer and secure enterprise IT and OT environments across sites, supporting Windows Server, virtualization, networking, cloud (Azure/M365), PLC/SCADA integrations, backups, DR, segmentation and Zero Trust initiatives. Provide Tier 2/3 escalation, network/OT troubleshooting, monitoring, documentation, compliance support, and collaborate with infrastructure, security, and manufacturing teams to maintain production uptime.

Lead a small infrastructure engineering team to own cloud infrastructure, backend services, website, CI/CD, observability, and developer tooling. Set technical direction, improve reliability, scalability, security, and engineering effectiveness, drive incident readiness and operational practices, partner with product and business stakeholders, hire and mentor engineers, and balance long-term investments with fast-moving product needs.

Lead Net at Work's internal IT organization, ensuring reliability, security, scalability, and performance across applications, infrastructure, cloud, and cybersecurity. Oversee application rollouts, SDLC practices, operations, vendor relationships, budgeting, and acquisition due diligence. Partner with executives and business leaders to align technology roadmaps, governance, and service delivery while building a service-oriented, high-performing IT team.

Lead and manage mid-to-low risk IT projects affecting multiple departments. Develop and maintain project plans, scope, schedules, budgets, risk and issue logs. Coordinate resources, vendors, and stakeholders; ensure communication, change control, transitions to support, and project delivery within PMO standards.