Top Remote IT Jobs in St. Louis, MO

Supports a six-month Epic Gallery implementation, including build, configuration, workflow design, document management migration, validation, and knowledge transfer. Acts as the Gallery subject matter expert while training an OnBase administrator and collaborating with HIM staff. Documents configuration decisions, provides best-practice guidance, and ensures workflows align with operational requirements. The role is part-time, primarily remote, and requires minimal onsite travel.

Designs and supports scalable cloud data warehouses for CMS healthcare fraud, waste, and abuse analytics. Responsibilities include data modeling, healthcare interoperability, secure HIPAA-compliant governance, lineage, testing, CI/CD, automation, workflow scheduling, and technical architecture. The role integrates claims and healthcare domains using Snowflake and industry standards while collaborating with stakeholders, documenting solutions, and leading warehouse project delivery.

Principal frontend-focused software engineer responsible for leading frontend architecture, standards, tooling, accessibility, performance, testing, and deployment practices. The role delivers scalable customer-facing web applications, component libraries, and design systems using React or Angular. It includes cross-functional product collaboration, technical decision-making, mentoring, modernization initiatives, and occasional full-stack work. The position is remote, requires U.S. citizenship, Public Trust 6C eligibility, and approximately 0–10% business travel.

Owns the vision, strategy, roadmap, feature definition, release planning, and performance measurement for IT clinical solution products. Partners with business and technical stakeholders on build-versus-buy decisions, architecture, licensing, change management, KPIs, ROI, migration, risk mitigation, and product adoption. Coordinates cross-functional delivery and vendor relationships while adapting product direction to changing business needs.

Leads complex enterprise technology projects across business, product, and engineering teams. Responsibilities include project planning, roadmap development, risk and dependency management, delivery governance, release coordination, stakeholder communication, KPI tracking, resource and budget management, process improvement, and team coaching. The role promotes Agile and modern delivery practices while ensuring quality, execution accountability, and alignment with strategic business objectives.

Develop and configure ServiceNow applications, workflows, scripts, and custom solutions to automate business processes. The role involves collaborating with customers, troubleshooting applications and integrations, supporting deployments, ensuring software compliance, evaluating system interfaces, and documenting testing and maintenance. Candidates should have a bachelor’s degree and relevant ServiceNow development experience. The position is fully remote, requires U.S. citizenship, and involves no travel or security clearance.

Owns IT systems administration and security operations for a fully remote workforce. Responsibilities include managing Microsoft 365 and Google Workspace, endpoint and identity platforms, security tools, access controls, threat monitoring, incident response, vulnerability management, compliance evidence, disaster recovery, vendor relationships, reporting, and operational roadmaps.

Leads the strategic direction of backend and full-stack engineering, architects scalable distributed systems and microservices, and drives modernization, reliability, security, and performance initiatives. Designs APIs, data architectures, pipelines, infrastructure, and observability practices; delivers customer-facing service improvements; establishes engineering standards; and mentors engineers. Collaborates across product and technical teams to make architecture and business trade-offs and lead large-scale initiatives from vision through production.

The Lead Technical Support Engineer resolves complex technical issues, provides mentorship, collaborates with teams, and improves support systems.

Own FAR.AI’s internal IT and security function, including accounts, devices, identity and access management, onboarding, offboarding, office networking, support, endpoint hardening, data protection, governance, and vendor risk. The role will remediate security gaps using threat modeling, automate self-service infrastructure, partner across teams, communicate and manage change, and hire and lead an IT Coordinator.

Own Flex’s IT and corporate security function as a hands-on senior individual contributor. Responsibilities include identity and access management, joiner-mover-leaver processes, Okta and Google Workspace administration, endpoint and MDM programs, SaaS governance, access reviews, security policies, awareness training, MSP management, and automation using scripts and internal tooling. The role partners with security, People, Finance, and Legal while maintaining corporate security posture across a distributed workforce.

Leads enterprise IT strategy, portfolio management, AI governance and enablement, cybersecurity initiatives, change management, communications, GxP validation and audit readiness. Oversees IT governance, operating-model improvements, budgeting, forecasting, vendor relationships, and cross-functional coordination. Partners with executives and business system owners to prioritize initiatives, manage risks, support regulated systems, and drive digital transformation across the biotechnology organization.

Identify and qualify potential clients through online research, databases, social media, email, cold calls, and social messaging. Maintain accurate CRM records, nurture early-stage opportunities, pass qualified prospects to sales, collaborate with sales and marketing, and monitor lead-generation metrics and campaign effectiveness. Fluency in English and Vietnamese is required for this SaaS or technology-focused sales development role.

Partners with IT hiring managers to develop talent acquisition strategies, source and screen candidates, build diverse pipelines, and present qualified talent. Provides recruiting consultation, interview guidance, offer support, vendor coordination, TA systems maintenance, reporting, and special-project leadership. Helps maintain recruiting policies, procedures, communications, and organizational talent acquisition programs while mentoring colleagues and promoting Navitus’ employment brand.

Lead the design and operation of a cloud-first IT environment, including SaaS administration, endpoint management, security, automation, email platforms, and AI-powered workflow agents. The role drives cross-functional IT projects, mentors team members, maintains standards and documentation, resolves complex escalations, and supports onboarding and escalated tickets. Key responsibilities include managing Google Workspace, Proofpoint, Slack, Okta, Jamf, Intune, and related systems while improving reliability, security, and operational efficiency.

Manages and optimizes procurement operations, Coupa workflows, supplier onboarding, purchase orders, invoices, and procurement integrations. Maps and improves business processes, implements ITGC-compliant changes, leads testing and sign-off, develops spend and supplier performance reporting, and resolves invoice and purchase order discrepancies. Drives Coupa Supplier Portal, CXML onboarding, and e-invoicing adoption while partnering with finance, accounts payable, stakeholders, suppliers, and Coupa support.

The IT Systems Engineer will architect and maintain Tempo's IT infrastructure, focusing on identity management, endpoint security, and automation, ensuring efficient provisioning and compliance.

Assesses segregation of duties, access controls, user entitlements, privileged access, and governance processes across enterprise applications. Supports audits, control testing, risk assessments, remediation, access certifications, and audit readiness for federal and DoD stakeholders. Develops workpapers, findings, corrective action plans, reports, and compliance documentation while collaborating with application owners, auditors, cybersecurity teams, and governance personnel.

Leads secure, reliable IT infrastructure supporting distributed clinical research sites and remote employees. Manages enterprise networking, Azure and Microsoft 365 services, endpoint platforms, automation, AI-enabled operations, vendors, budgets, and technology projects. Oversees site deployments, security and compliance initiatives, service delivery, and operational improvements while recruiting, coaching, and developing technical teams.

Evaluates IT infrastructure, applications, cybersecurity, compliance, costs, scalability, and compatibility during mergers and acquisitions. Leads technology integration and separation planning, identifies modernization and consolidation opportunities, conducts IT capability and maturity assessments, recommends governance frameworks, and aligns technology strategy with business objectives. The role also prepares diligence reports and executive presentations while collaborating with internal and external stakeholders in fast-paced transaction environments.

Provides application and system support, troubleshoots issues, manages testing and deployments, develops ETL tools and reports, and conducts business analysis. The role defines requirements, identifies IT solutions, supports system integrations, documents procedures, guides team members, and communicates with stakeholders. It also applies agile practices and supports process improvements within a financial services environment.

Designs and manages AWS cloud infrastructure and Amazon EKS platforms using GitLab CI/CD and Infrastructure as Code. Builds ETL workflows and scalable data pipelines for analytics and AI workloads, supports MLOps/AIOps and FinOps capabilities, troubleshoots Linux systems, and improves platform performance, security, scalability, and availability.

Provides enterprise technical leadership for cloud and network modernization across DoD environments. Engineers multi-cloud integrations, secure connectivity, cloud access points, routing and switching, data center technologies, F5 ADC solutions, and Zero Trust architectures. Leads migration planning, compliance with DoD security frameworks, Tier 3/4 troubleshooting, technical documentation, executive recommendations, and cross-disciplinary initiatives. The hybrid role supports DLA and requires periodic onsite work for NIPR/SIPR operations.

Build and evolve scalable generative AI software, including an agentic framework powering Atom AI and an AI asset portal. Develop production-ready web, data, and AI solutions; evaluate emerging models and frameworks; promote responsible AI practices; and ensure solutions are maintainable, cost-effective, and scalable. Partner with stakeholders, lead complex projects, demonstrate solutions, participate in strategy and ideation, and mentor other developers.

Build integrations, automation, analytics pipelines, dashboards, and self-service tools for enterprise workforce AI platforms including Microsoft Copilot, Claude, and Glean. Develop adoption and usage reporting, automate platform administration and licensing governance, support AI enablement programs, and integrate privacy, security, and responsible AI practices. Lead complex projects, mentor developers, collaborate with stakeholders, demonstrate solutions, and recommend technology and process improvements.