Top Remote Python Jobs in San Diego, CA

Lead and mentor a distributed infrastructure team to maintain and scale Airship's GCP cloud environment. Drive CI/CD, observability, automation, cost optimization, security, incident response, and infrastructure projects while collaborating cross-functionally and participating in hiring.

The Solutions Operations Lead manages AWS cloud operations, overseeing deployment automation, DevSecOps practices, and infrastructure reliability while mentoring engineering teams and ensuring compliance and security.

Run and improve Buffer's production platform: keep EKS, ArgoCD, and AWS reliable; implement progressive delivery (Argo Rollouts); build developer-facing tools and per-PR environments; reduce toil with AI automation; manage observability and cloud cost; drive lifecycle upgrades and security; partner with engineering teams and participate in on-call rotations.

Responsible for designing, deploying, and supporting enterprise file storage solutions in Azure, focusing on Qumulo file storage and Azure services, ensuring security, performance, and cost-effectiveness.

As a Senior Implementation Engineer, you will design and implement DevSecOps and CI/CD solutions for enterprise customers, optimizing their Harness setups for efficiency and scalability while engaging with technical teams and leadership.

Design, build, and maintain scalable, secure cloud infrastructure and SRE practices. Implement IaC, Kubernetes/Helm deployments, CI/CD pipelines, monitoring/observability, automation, security/compliance, capacity planning, and mentor junior engineers to ensure reliability and performance.

Design, build, and maintain scalable end-to-end systems and APIs/SDKs for an enterprise custody platform. Work full-stack across databases, cloud deployments, CI/CD, and security; troubleshoot issues, integrate emerging technologies, and mentor junior engineers.

Design, build, and operate Azure foundational components (network, security, identity, governance). Automate deployments (IaC), monitor and scale production SaaS, troubleshoot incidents, define cloud best practices, and collaborate across teams to improve reliability, performance, and cost-efficiency.

Lead and guide development teams, ensure successful project delivery, translate business requirements into applications, uphold best practices in software development and DevOps.

As an AWS Technical Architect, you will ensure customer success with Amazon Connect solutions, conduct technology assessments, educate clients on AWS, and manage technical teams. You'll translate customer needs into effective designs, oversee project deliverables, and provide training while driving best practices in contact center design.

The Principal Software Research Engineer will lead research in distributed systems, develop innovative solutions, interface with sponsors, and transition research to product development while managing project proposals and reports.

Lead architecture and hands-on development of cloud-native, microservices-based systems and company-wide integrations (AWS and MuleSoft) using Python. Own provisioning, billing, telemetry, and integration landscapes; define AI-SDLC and AI tooling; implement infrastructure-as-code and CI/CD; ensure observability, testing, security, and operational readiness; translate architecture into Jira work and mentor engineering teams.

The Senior Software Engineer will design and develop backend systems and APIs, mentor other engineers, and resolve complex integration challenges in healthcare technology.

Design, implement, and support Kubernetes and compute platforms in a private cloud. Oversee architecture and standardization across hardware, OS, and cloud orchestration.

The role involves designing CLI and backend services, maintaining code quality, collaborating on technical issues, and writing documentation.

Design and govern large-scale Elasticsearch architectures and migrations. Build high-throughput indexing and semantic vector search (kNN, ANN, ELSER) and RAG pipelines. Optimize performance, capacity, and cluster topology across cloud platforms, influence product roadmap, publish best practices, and mentor engineering teams and enterprise customers.

As a Senior Software Engineer at Ayama, you will build and improve AI-based systems, design data pipelines, and develop full-stack product features. This role requires strong architectural judgment and hands-on experience with optimization problems and large-scale data processing.

We are seeking a software engineer to build and validate resilient distributed systems, enhance CI pipelines, and improve testing strategies for cloud applications.

Maintain availability, monitoring, and incident response for BeyondTrust Cloud Service. Troubleshoot distributed systems, implement fixes and preventive measures, collaborate across teams to meet SLAs, document work, follow risk/compliance, and drive automation and continuous improvement.

Lead post-sales integrations and implementation projects for software partners, translating business needs into technical solutions, managing project plans, documentation, KPIs, and cross-functional coordination while providing ongoing integration support and product expertise for Payabli's payments platform.

The Senior Software Engineer will develop backend systems, mentor engineers, and collaborate with cross-functional teams while contributing to product features and roadmaps.

Lead development and enhancement of mathematical optimization algorithms and APIs (LP, MIP, QP, etc.). Implement, benchmark, and document new solver features, support product releases, present at conferences, and collaborate with global teams to improve performance and numerical robustness.

The Mongo Database Engineer will design and implement database solutions, enhance security, lead automation processes, and optimize database structures, contributing to national security initiatives.

The Web3 / Full-stack Software Engineer will design, develop, and deploy software solutions for staking products, collaborating with engineers and UX designers to enhance UI and ensure security of blockchain networks.

Implement, automate, and maintain multi-cloud infrastructure and services. Build CI/CD pipelines and infrastructure-as-code, develop automation scripts and tooling, monitor performance and cost, troubleshoot issues, and document architecture and operational decisions while partnering with product and engineering teams to improve scalability, reliability, and security.