Top Remote Python Jobs in Houston, TX

Build and operate Origin’s AI observability platform across data-collection agents, backend services, infrastructure, inference pipelines, APIs, and React interfaces. Design distributed systems using AWS, EKS, ClickHouse, and Kafka for high-throughput, multi-tenant production workloads. Develop internal coding agents and define AI-native engineering practices while making decisions around storage, APIs, performance, and reliability.

Define architecture and metrics for autonomous driving evaluation, lead cross-functional integration across autonomy and simulation teams, develop statistical and machine learning methods, analyze large-scale time-series data, manage evaluation KPIs and release gates, and communicate safety and readiness insights through dashboards and stakeholder presentations.

Develop and maintain Xactly Connect integration pipelines, transformations, schedules, and data exchanges. Partner with finance, sales compensation, accounting, sales, and IT stakeholders to define requirements. Troubleshoot data quality issues, failed jobs, mismatches, and pipeline errors before commission runs. Document configurations, mappings, and transformation logic while supporting continuous improvement.

Lead and grow a software engineering team responsible for CUDA Math Libraries platform expansion and readiness. Own integration, qualification, compliance, validation, performance testing, defect triage, and technical roadmaps across specialized platforms. Collaborate with library, DevOps, QA, compiler, CUDA, release, and platform teams. The role requires hands-on high-performance numerical software development using C++ and Python, parallel computing, performance optimization, and software engineering leadership.

Serve as a technical partner for utility customers across pre-sales discovery, implementation scoping, pilots, and end-to-end deployments. Build integrations with asset management, GIS, inspection, and reporting systems; develop reusable deployment tooling and AI agents; address security and architecture concerns; identify expansion opportunities; and translate recurring field needs into product improvements. The role is approximately 80% customer-facing and requires close collaboration with Sales, Product, Solutions, and Engineering.

Reviews and audits high-definition map datasets for accuracy, completeness, and safety-critical defects. Performs quality control on geospatial data derived from LiDAR, imagery, and vehicle sensors; documents and triages issues; defines QC metrics, sampling strategies, and repeatable workflows; collaborates with mapping engineers, autonomy teams, and vendors; analyzes defect trends; maintains procedures; and supports launch readiness for new corridors and operational domains.

Designs, develops, and leads scalable healthcare software solutions involving transaction processing, interoperability standards, integrations, and data platforms. Provides hands-on engineering, architectural leadership, quality ownership, risk management, technical mentorship, and cross-functional collaboration. The role requires building high-performance cloud-based SaaS solutions using microservices and serverless architectures, while guiding engineering strategy and ensuring secure, reliable delivery.

Build and maintain full-stack components for a maritime domain awareness platform supporting sonar and sonobuoy data. Responsibilities include developing frontend pages and real-time data feeds, designing PostgreSQL and Apache Iceberg data models, modifying MQTT and Redpanda pipelines, managing Dagster batch workflows, integrating machine learning algorithms, and improving development and CI/CD tooling. The role is remote and involves mission-critical defense technology.

Build and maintain full-stack applications for a maritime data management and AI platform. Responsibilities include developing frontend components, real-time WebGPU data feeds, PostgreSQL and Apache Iceberg data models, MQTT and Redpanda pipelines, Dagster batch workflows, machine learning integrations, and CI/CD tooling. The role supports mission-critical products used with U.S. Navy sonar and sonobuoy data.

Design, build and maintain Microsoft Cloud applications using Power Apps/Pages and Azure services. Implement Entra ID authentication, Azure Functions/App Services, Logic Apps and Blob storage. Create Azure Data Factory pipelines and APIs (REST/GraphQL), integrate external services and LLM data pipelines, and ensure performance, security, and scalability while collaborating with customers to turn requirements into streamlined apps.

Build and scale full-stack applications using Ruby on Rails, React, PostgreSQL, Docker, Kubernetes, and Terraform. Design APIs, data architectures, synchronization systems, infrastructure, and CI/CD pipelines for secure, reliable operation in disconnected and low-bandwidth environments. Collaborate across engineering, business development, and mission teams while supporting critical defense and public safety operations.

Support and evolve development, production, and non-production infrastructure. Maintain GitLab CI/CD pipelines, automate operational tasks with Python and Bash, manage cloud and virtualized environments, troubleshoot incidents, perform root cause analysis, support vulnerability remediation using Tenable Nessus and Wiz, and maintain technical documentation in Jira and Confluence.

Design and optimize large-scale GPU clusters spanning compute, networking, storage, and control planes. Model AI workload performance, architect InfiniBand and RoCEv2 interconnects, integrate high-performance storage, assess reliability and monitoring signals, and collaborate with infrastructure teams to operationalize architectures across data centers.

Develops automated hardware and software test solutions for photonic integrated circuits and subassemblies. Responsibilities include designing validation plans, characterizing semiconductor optoelectronic devices, controlling instruments and data acquisition, qualifying production test stations, applying Gage R&R and SPC, documenting solutions, and tracking project milestones. The role requires collaboration across engineering teams and troubleshooting of complex test systems.

Build and operate Helius’s bare-metal infrastructure platform. Responsibilities include automating server provisioning and lifecycle management, developing fleet tooling, standardizing CI/CD and deployment processes, implementing security controls, analyzing infrastructure costs, improving observability, participating in on-call response, and documenting operational procedures.

Lead design and implementation of Pinterest Edge systems (CDN, TLS, DNS, proxies) to manage automation traffic and rate limiting at scale. Develop request-processing logic in Envoy, collaborate with vendors and platform teams, mentor engineers, use AI to accelerate workflows, and participate in on-call incident response and reliability improvements.

Owns external partner and merchant integrations from discovery through launch and production support. Designs integration paths, guides partner developers, validates implementations, troubleshoots issues using observability and technical tools, and coordinates with Engineering, Product, and Sales. The role also improves integration processes, documentation, ticketing, partner communications, and automation opportunities while translating complex technical concepts for external partners.

Design, build, and maintain software using Domain-Driven Design, event-driven architecture, CQRS, and Event Sourcing. Use Cursor and Claude to plan, write, refactor, and test code. Collaborate with small teams, product owners, clients, and engineers to solve business problems, translate requirements into maintainable systems, and mentor teammates on architecture and agentic development workflows.

Leads architecture and development of Trellix’s high-throughput cloud threat detection platform. Designs microservices, asynchronous submission pipelines, sandbox execution systems, full-stack analyst interfaces, secure AWS infrastructure, identity integrations, telemetry pipelines, and compliant multi-region architectures. Owns infrastructure as code, observability, production reliability, security practices, technical documentation, incident response, and SLA commitments while integrating AI-assisted development tools.

Designs, operates, and improves scalable cloud and on-premise infrastructure, CI/CD pipelines, Kubernetes platforms, data streaming systems, and observability tooling. Owns AWS reliability, security, cost efficiency, automation, progressive deployments, incident response, and production troubleshooting. Partners with software engineering teams to integrate services and drive continuous improvements in system performance, scalability, and uptime.

Build and scale reliable software systems supporting donor platforms, cash payments, and rapid-response programs. Own features end to end from architecture through deployment and monitoring, improve CI/CD and testing, troubleshoot production issues, and collaborate with product, operations, and data teams. The role also contributes to technical roadmaps and sustainable engineering practices in a mission-driven, fully remote organization.

Executes systems engineering across R&D platforms, hybrid cloud, SaaS, HPC, containers, integrations, data pipelines, observability, and AI architectures. Coordinates Enterprise IT, vendors, cybersecurity, compliance, and scientific stakeholders to deliver secure, scalable, validated, and supportable solutions. Develops technical documentation, deployment plans, runbooks, monitoring, lifecycle artifacts, risk logs, and operational handoffs. Implements RAG, vector database, AI gateway, agentic workflow, and multimodal integration patterns while supporting cloud migration, change management, governance, and technical issue resolution.

Owns end-to-end QA coverage across firmware, cloud services, and mobile applications for IoT products. Tests device-to-cloud communication, APIs, business logic, connectivity failures, offline operation, OTA updates, and rollback scenarios. Analyzes device and cloud logs, develops test data strategies, prioritizes automation scenarios, and maintains smoke and regression testing processes. Requires systems thinking, embedded and mobile testing experience, API testing, Agile QA processes, and familiarity with relevant test management tools.

Own and evolve scalable distributed systems, REST APIs, backend services, and core product areas. Design solutions, improve resilience, reduce technical debt, and drive modularization. Use AI-first and agentic development practices, evaluate emerging AI tools, and help integrate AI across engineering workflows. Collaborate asynchronously with product, data, and go-to-market teams while improving engineering tools, processes, and system reliability.

Build and operate AWS GovCloud data infrastructure across development, preproduction, and production environments. Establish PostgreSQL platforms, infrastructure-as-code with Chef, BI infrastructure, identity integrations, monitoring, observability, CI/CD, and disaster recovery. Support data pipelines, troubleshoot incidents, optimize databases, and ensure FedRAMP and FISMA compliance. Collaborate with security, compliance, DevOps, and data engineering teams while delivering greenfield infrastructure from architecture through production.