Top Remote Python Jobs in Houston, TX

Design, build, ship, and support backend services and end-to-end features focused on reliability, scalability, and performance. Debug production issues, write and debug SQL, follow testing best practices, collaborate in a remote team, participate in on-call, and contribute to architecture and roadmap decisions.

Design, build, ship, and maintain end-to-end product features across frontend, backend, and data layers. Own projects from definition through production, improve reliability and scalability, collaborate with product and design, mentor engineers, and engage with customers to solve real user problems.

Design, develop, and maintain scalable, secure backend services and APIs for a healthcare caregiver platform. Drive cloud-native modernization (microservices, serverless), ensure compliance (HIPAA, OWASP), troubleshoot production issues, optimize performance, mentor junior engineers, and collaborate with product and architecture teams to deliver reliable, high-performing solutions.

Lead and grow a payments engineering team responsible for payment platforms, integrations, tokenization, fraud signals, and reconciliation. Own delivery, production stability, on-call, PCI DSS compliance, vendor relationships, budget, and cross-functional coordination. Drive reliability, incident response, roadmap execution, and measurable improvements in transaction success, latency, and error budgets.

Design, build, scale, and operate a Kafka-compatible, object-storage-backed streaming platform. Own backend services, storage engine, multi-tenant control plane, transactions and multi-region features. Troubleshoot complex distributed systems, ensure operational readiness and SLAs, participate in on-call rotation, and contribute across the full stack including developer console UI.

Lead architecture and roadmap for a company-wide data lakehouse platform. Build platform-as-product components (SDKs, CLIs, control planes), optimize distributed compute/storage, prototype performance R&D, ensure compliance-by-design (lineage, PII masking, access control), enable real-time AI data ingestion, drive engineering standards, and mentor cross-functional teams.

Build and evolve APIs and frontend surfaces for data products. Translate business requirements into scalable systems, ensure data integrity, design frontend and backend architecture, improve developer self-serve tooling, collaborate with stakeholders, and mentor engineers while maintaining strong code quality and delivery practices.

The GTM Engineer will enhance and manage enrichment infrastructure, scoring pipelines, and event tooling while writing production code and ensuring data accuracy within GTM operations.

As a Full-Stack Software Engineer, you'll build user-facing features, optimize GraphQL backend, and develop scalable systems, contributing significantly to the company's growth.

The Staff Integrations Engineer will lead the development and delivery of healthcare data integrations across various systems, ensuring performance and reliability while acting as a technical advisor for customers.

Design and build platforms for new products, develop generative AI features, ensure system reliability, and foster a collaborative culture in a startup environment.

As a Founding Software Engineer, you'll design, develop, and maintain robust backend systems, create user-facing AI features, and collaborate with teams to enhance healthcare tools.

The Founding Product Engineer will build and scale product features, enhance engineering productivity, and collaborate with a diverse team to improve healthcare using AI.

As a Founding AI/Data Engineer, you'll design and build AI-driven products, collaborate across teams, and ensure system reliability while enhancing user experiences.

The role involves designing and advancing infrastructure for the engineering team, ensuring the reliability of Kubernetes clusters, automating operations, and building machine learning infrastructure.

The Senior Software Engineer II at Freenome will design and develop reliable backend services, mentor junior engineers, and collaborate with cross-disciplinary teams in a remote setting.

Lead development and optimization of fabrication processes for integrated photonic devices (electro-optic materials). Design experiments, own wafer lots at foundries, define metrology and failure analysis, improve yields, collaborate with internal and external photonics engineers, and implement process improvements to reduce loss and scale production.

Lead and support design, deployment, administration, and Tier-2/3 support of AWS and hybrid-cloud systems. Maintain Linux/Windows servers, IP networking, automate operations with IaC/configuration management, produce documentation, and troubleshoot mission-critical infrastructure in a secured, fast-paced environment.

Build and maintain the core backend product: design and implement features, take ownership of end-to-end outcomes, iterate and fix bugs without a QA team, collaborate with product on scoping, and contribute to company culture and hiring.

Lead 24x7 application support for external web applications: manage incidents, perform RCA, implement preventative fixes, build monitoring/alerts, expand Splunk functionality, create dashboards, collaborate with development and platform teams, and participate in on-call rotation.

Lead technical direction for a major product domain, reduce architectural debt, mentor engineers, standardize AI-agent workflows, and design scalable backend solutions integrating LLMs and cloud services. Drive cross-team RFCs, cookbook standards, and adopt agentic AI tooling while balancing security, quality, and delivery.

The role involves designing and maintaining scalable cloud infrastructure, optimizing CI/CD pipelines, and mentoring junior engineers while focusing on improving developer experience.

The Energy Engineer will integrate building automation systems data into Ameresco's platform, support on-site gateways, and ensure data quality while collaborating with stakeholders and customers.

Support integration of a hybrid mainframe-to-cloud prototype by implementing secure network connectivity, Kubernetes container platforms, CI/CD and IaC automation, system integrations (APIs, messaging), DevSecOps security controls, and environment operations. Assist troubleshooting, testing, documentation, and knowledge transfer while aligning deployments with DoD security requirements.

Design, develop, and maintain automated functional, performance, and security test scripts for the GEOMAP platform. Integrate tests into CI/CD using government-approved tools, convert manual tests to automation, perform regression/performance/interoperability testing, maintain traceability and test artifacts, collaborate with Scrum teams, support government third-party testing, and participate in defect triage and root cause analysis.