Top Remote Python Jobs in Houston, TX

Reposted 7 Days AgoSaved
In-Office or Remote
Remote Houston, TX
Expert/Leader
Expert/Leader
Fintech • Financial Services
Lead and modernize global endpoint engineering across Windows, macOS, ChromeOS and VDI/DaaS platforms. Own OS/image lifecycle, endpoint configuration/hardening, Intune/Autopilot and SCCM co-management, VDI performance, and endpoint security controls. Partner with Security, Risk, and Desktop Operations for audit readiness, telemetry-driven improvements, and scalable production rollout.
Top Skills: Asr (Attack Surface Reduction)AutopilotAws AppstreamAws WorkspacesAzure AdBitlockerChromeosCitrixCitrix CloudCloud PcConditional AccessGoogle Admin ConsoleHorizonIvantiJAMFmacOSMicrosoft DefenderMicrosoft IntuneNexthinkPowershellPythonSccmTaniumWindows 10Windows 11
Reposted 7 Days AgoSaved
Remote
Remote Houston, TX
165K-180K Annually
Senior level
165K-180K Annually
Senior level
Healthtech • Software
Lead design, architecture, and hands-on implementation of scalable healthcare SaaS systems. Drive interoperability (HL7, FHIR, EDI), mentor engineers, liaise with stakeholders, manage technical risk, and ensure quality, performance, security, and innovation.
Top Skills: AgileAWSC#DevOpsEdiFhirHl7JavaMicroservicesMirth ConnectNoSQLPostgresPythonSaaSServerlessSQL Server
7 Days AgoSaved
Remote
Remote Houston, TX
Senior level
Senior level
Pharmaceutical
Lead test strategy within sprint teams, design and maintain automated API and UI tests and frameworks, create test plans and metrics, find and track defects, and improve CI/CD, security, and performance testing using automation and AI tools.
Top Skills: APIsCircleCIClaudeCopilotCypressGithub ActionsJavaJavaScriptJenkinsPage Object ModelPlaywrightPlaywright McpPytestPythonRest AssuredSeleniumTypescript
7 Days AgoSaved
Remote
Remote Houston, TX
1M-2M Annually
Senior level
1M-2M Annually
Senior level
Agency • Information Technology • Software • App development
Design, develop, and maintain scalable Python applications and cloud-native solutions. Architect microservices, containerized deployments (Docker/Kubernetes), optimize cloud infrastructure, build CI/CD pipelines, integrate messaging systems, ensure security and high code quality, and mentor junior developers. Generative AI/ML experience is a plus.
Top Skills: AWSAzureAzure PipelinesCi/CdCosmosdbDjangoDockerFastapiFlaskGenerative AiGitlab CiGCPHugging FaceJenkinsKafkaKubernetesPythonPyTorchRabbitMQRdsRest ApisServerlessTensorFlowWebsockets
7 Days AgoSaved
In-Office or Remote
Remote Houston, TX
Senior level
Senior level
Artificial Intelligence • Healthtech • Insurance • Software
Build and maintain scalable backend systems and data pipelines for healthcare workflows. Collaborate cross-functionally to automate provider and patient workflows, prototype features, ship production-ready code, and ensure systems are maintainable and scalable.
Top Skills: APIsEhrETLFastapiFlaskNext.JsPostgresPythonReactSqlalchemy
7 Days AgoSaved
Remote
Remote Houston, TX
30K-80K Annually
Senior level
30K-80K Annually
Senior level
Artificial Intelligence • Software • Consulting • Cybersecurity
Design and build scalable backend systems, data pipelines, and cloud infrastructure. Own CI/CD, containerization, databases, and reliability; collaborate with tech leads to deliver secure, production-grade solutions for startups in a fully remote environment.
Top Skills: Apache KafkaAWSAzureCi/CdConfluent CloudDockerGCPKubernetesMlopsNode.jsNoSQLPulumiPythonSQLTerraformTypescript
7 Days AgoSaved
Remote
Remote Houston, TX
135K-150K Annually
Mid level
135K-150K Annually
Mid level
Artificial Intelligence • Big Data • Healthtech • Analytics
Build and optimize high-throughput de-identification pipelines for large clinical datasets, execute QA, run and tune pipelines in health system cloud environments, reduce errors and costs, and collaborate with privacy and clinical informatics stakeholders.
Top Skills: AWSAzureBashDockerPandasParquetPythonRedshiftSnowflakeSQLVMware
7 Days AgoSaved
Remote or Hybrid
Remote Houston, TX
Mid level
Mid level
Artificial Intelligence • Edtech • Enterprise Web • Software
Join as a full-stack software engineer to design, develop, and maintain web applications and services. Collaborate cross-functionally, write clean code, perform code reviews, debug issues, and stay current with industry trends.
Top Skills: CSSHTMLJavaJavaScriptPythonTypescript
Reposted 7 Days AgoSaved
Remote
Remote Houston, TX
Junior
Junior
Information Technology • Professional Services • Software • Consulting
We are seeking a Software Engineer with 1-3 years of experience to join our technology enablement program and focus on Zoho technologies. The role involves designing and implementing digital transformation solutions, requires technical and soft skills, and offers hands-on training and client-facing work.
Top Skills: AngularCSSHTMLJavaJavaScriptMySQLNode.jsPHPPostgresPythonReactRestful ApisVueZoho AnalyticsZoho CreatorZoho Crm
7 Days AgoSaved
Remote
Remote Houston, TX
Senior level
Senior level
Information Technology • Consulting
Manage and optimize large-scale Ubuntu and RHEL servers, perform upgrades, patching, performance tuning, security hardening, backups and disaster recovery. Maintain configuration management and deployment pipelines (Ansible/Puppet/Terraform), monitor system health, troubleshoot OS/hardware/network issues, collaborate with DevOps/Cloud teams for provisioning, and produce documentation, SOPs, and audit reports.
Top Skills: AnsibleAWSAzureBashCi/CdDhcpDnsDockerFirewallsGCPGitHigh-Availability ClustersKvmLinuxLoad BalancingNagiosNfsPrometheusPuppetPythonRaidRed Hat Enterprise Linux (Rhel)Server HardeningShellSshSsl CertificatesTerraformUbuntuVMwareZabbix
Reposted 7 Days AgoSaved
Remote
Remote Houston, TX
Mid level
Mid level
Industrial
As a Backend Engineer, design and manage backend infrastructure, develop microservices, optimize data systems, collaborate with teams, and participate in on-call rotations.
Top Skills: Api GatewayAws LambdaMySQLPythonTerraform
Reposted 7 Days AgoSaved
Remote
Remote Houston, TX
180K-200K Annually
Senior level
180K-200K Annually
Senior level
Artificial Intelligence • Software
Design high-performance C++ libraries for automated PCB design challenges, mentoring peers and shaping technical direction while collaborating with experts in various fields.
Top Skills: C++CudaPython
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Reposted 7 Days AgoSaved
Remote
Remote Houston, TX
Senior level
Senior level
Artificial Intelligence • Fintech • Software • Financial Services
Design and build AI-powered backend services, optimizing performance and scalability while collaborating with cross-functional teams to integrate generative AI models.
Top Skills: AWSClickhouseDockerGitGradleJavaJenkinsKafkaKubernetesMavenPython
Reposted 7 Days AgoSaved
Remote
Remote Houston, TX
Senior level
Senior level
Artificial Intelligence
The Senior Backend Engineer will design and implement infrastructure for an AI system, solve complex data-related problems, and ensure system scalability and security.
Top Skills: Cloud InfrastructureGoObservability ToolingPostgresPython
Reposted 7 Days AgoSaved
Remote
Remote Houston, TX
128K-267K Annually
Senior level
128K-267K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
Design and optimize storage systems at scale, implementing caching strategies and ensuring data availability and performance for a large user base.
Top Skills: AWSCloud SpannerGCPGoJavaMemcachedPythonRedisSQLValkey
Reposted 7 Days AgoSaved
Remote
Remote Houston, TX
140K-160K Annually
Senior level
140K-160K Annually
Senior level
Artificial Intelligence • Software
As a Solutions Engineer, you will troubleshoot and resolve complex technical issues, advise enterprise customers, and influence product direction while collaborating with technical and sales teams.
Top Skills: 802.11APIsCloud-Managed IotDhcpDnsFirewallsLinuxNatNetworkingPythonTcp/IpTls/HttpsVlans
Reposted 7 Days AgoSaved
Remote
Remote Houston, TX
Senior level
Senior level
Artificial Intelligence • Insurance
The Software Engineer will build features across the stack, design AI/LLM-driven workflows, translate requirements, and collaborate closely with the founding team and customers.
Top Skills: Amazon DynamodbAmazon EcsAWSAws LambdaFastapiNextjsPostgresPythonReactS3Typescript
Reposted 7 Days AgoSaved
Remote
Remote Houston, TX
230K-280K Annually
Senior level
230K-280K Annually
Senior level
Artificial Intelligence • Information Technology • Software
The role involves building and scaling platform components, collaborating with product teams, and setting technical direction for features. Requires experience in backend engineering.
Top Skills: Frontend FrameworksGoKubectlPythonReactRest ApisTerraform
Reposted 7 Days AgoSaved
Remote or Hybrid
Remote Houston, TX
Mid level
Mid level
Digital Media • Software
You will design and implement scalable backend systems integrating August infrastructure with third-party DeFi protocols while collaborating with engineering teams.
Top Skills: MongoDBPostgresPython
Reposted 7 Days AgoSaved
Remote
Remote Houston, TX
175K-230K Annually
Senior level
175K-230K Annually
Senior level
Fintech • Software • Financial Services
The Senior Full-Stack Software Engineer will design, build, and scale backend services and APIs for financial transactions while collaborating with frontend engineers and contributing to technical design.
Top Skills: AWSDjangoPostgresPythonReactTypescript
Reposted 7 Days AgoSaved
Remote
Remote Houston, TX
Senior level
Senior level
Information Technology • Financial Services
The Backend Engineer will design, build, and scale Veda's backend systems, ensuring reliability and performance for DeFi applications.
Top Skills: AWSAzureC++DockerGCPGoJavaKubernetesMySQLPostgresPythonRust
Reposted 7 Days AgoSaved
Remote
Remote Houston, TX
Senior level
Senior level
Information Technology • Software • Consulting
As a Contract Senior Web Services Engineer, you will design APIs, implement databases, and develop solutions while collaborating with cross-functional teams to solve complex technical problems.
Top Skills: DjangoGinGoGraphQLNestjsNode.jsOpenaiPythonRestful ApisSalesforceShopifySQLStripe
Reposted 7 Days AgoSaved
Remote
Remote Houston, TX
150K-210K Annually
Senior level
150K-210K Annually
Senior level
Big Data • Cybersecurity
The Senior Software Engineer will enhance AI system reliability, performance, and scalability, focusing on distributed services and collaborating with ML researchers.
Top Skills: JavaKotlinKubernetesLoggingMetricsPythonRelational DatabasesScalaTracing
Reposted 7 Days AgoSaved
Remote
Remote Houston, TX
Mid level
Mid level
Information Technology • Consulting
The Cloud Administrator manages cloud infrastructure and services, ensuring their performance, security, and reliability while troubleshooting issues and optimizing costs.
Top Skills: AWSAzureBashGCPPythonTerraform
Reposted 7 Days AgoSaved
Remote
Remote Houston, TX
156K-209K Annually
Mid level
156K-209K Annually
Mid level
Insurance • Software
As an SDET, you'll develop and maintain test automation frameworks, ensure API quality, collaborate with teams, and mentor others in testing practices.
Top Skills: Bdd FrameworksCi/CdGoPostgresPytestPythonSQLTestrail
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