Top Remote Software Engineer Jobs in Buffalo, NY

Build and scale ML-optimized HPC infrastructure, manage Kubernetes-based GPU/TPU superclusters, optimize for AI/ML training, and mentor teams while innovating in ML infrastructure.

Build and maintain reliable, secure, scalable backend systems for Lithic’s product platform. Own projects end to end across API key management, reliability, audit logging, search, and API infrastructure. Improve system reliability, reduce technical debt, participate in on-call rotations, and lead team process improvements while collaborating asynchronously across time zones.

Build and operate highly scalable storage infrastructure supporting petabyte-scale imagery data. Responsibilities include developing backend services and APIs, managing object storage and metadata indexing, tuning Elasticsearch, improving disaster recovery, monitoring performance, responding to incidents, contributing to architecture and roadmaps, and advising engineers. The role requires strong production software engineering experience with Go or Python, cloud-native systems, relational and non-relational databases, and highly available services.

Build and deploy integrations between the Bayesian platform and large EHR systems, implement automated integration and end-to-end tests, support production deployments and go-lives, develop tooling and automation (including LLMs), and collaborate with implementation and clinical teams to deliver clinician-facing workflows.

Lead technical strategy and architecture for Affirm Bank's cloud, data, vendor integrations, and operational tooling. Design, build, and operate high-stakes systems end-to-end, own incident response, vendor selection, and the Bank↔Affirm Inc integration boundary. Ensure examiner-ready documentation, compliance, reliability, and observability while mentoring engineers and pushing AI-assisted engineering practices to increase velocity and product safety.

As a Staff Frontend Software Engineer, you'll lead the frontend architecture using React and TypeScript, manage code releases, and integrate AI tools to enhance efficiency while ensuring high performance and system reliability.

Build and improve frontend interfaces for DogByte and other internal products used by veterinary hospitals. Own projects from problem framing through production release, collaborate with Design and Product, uphold accessibility and performance standards, evolve shared components and design systems, review technical work, and contribute to backend or full-stack development as needed. Apply AI tools thoughtfully across development workflows while maintaining quality and reliability.

Lead architecture and implementation of software for autonomous UAS systems; mentor engineers; ensure compliance with aerospace standards; optimize CI/CD pipelines.

Develop and enhance the new Stores platform while supporting various e-commerce tools to improve seller success online.

As a Software Engineer at Realm, you will develop backend services, create web and mobile UIs, and deploy tech at industrial sites. You will solve real-world challenges using various technologies and work with top leadership to build a stellar engineering team.

As a Front-End Engineer, you'll create intuitive UIs for AI tools, collaborating with design and backend teams, focusing on performance and user experience.

As a Senior Fullstack Software Engineer at Vanta, you will lead complex projects, set technical direction, design and develop new functionalities, and contribute to the engineering culture while mentoring other engineers.

The Software Engineer will develop and support the MEMX Trading system, focusing on high throughput event-sourcing applications and resolving production issues.

The role involves designing authentication and authorization solutions, integrating applications with identity platforms, and maintaining security practices within identity services. A focus on collaboration with Security and Product teams is important.

As a Software Engineer III, you'll develop custom software for government clients, teaching Agile practices, delivering software solutions, and ensuring client satisfaction through collaboration and feedback.

Seeking experienced Senior Backend Engineers to join a collaborative team, focusing on backend systems, shared services, and product features aimed at improving user experiences and monetization.

Design and implement DataPath on silicon. Write efficient, modular code with thorough testing. Requires experience in packet forwarding and virtualized Linux environments.

The Senior Full Stack Software Engineer will oversee technical development in a B2B SaaS healthcare environment, mentor junior engineers, and lead product features.

Design, develop, and maintain backend services and APIs for Speechify, focusing on performance, scalability, and user experience while collaborating with cross-functional teams.

The Senior Web Software Engineer will build and maintain web components, own features from inception to production, implement designs, partner with teams, and impact product evolution.

As a Senior Backend Software Engineer at Step, you'll own features from inception to production, improve Kotlin services, ensure code quality, and work collaboratively in a small team.

The Senior Mobile Software Engineer will develop user-facing features for a cross-platform app, ensuring code quality and functionality throughout the entire lifecycle of features.

Lead the bioinformatics pipeline team, setting technical strategy and architecture. Ensure engineering best practices, mentor staff, and oversee DevOps strategy for reliable software delivery in a regulated environment.

As a System Software Engineer, you will enhance GCC/LLVM toolchains for Ubuntu, ensuring modern C/C++ features and improving developer experiences through collaboration and high-quality coding.

Design, build, and operate highly available, high-throughput backend services for Twilio SendGrid. Modernize Go-based microservices, manage dual-cloud AWS/Azure infrastructure with Terraform, improve observability and reliability, mentor engineers, and balance feature delivery with platform refactoring.